• Clinical and Experimental Pediatrics
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• v.48 no.4
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• pp.369-375
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• 2005

Purpose : Many inborn errors of metabolism can be completely cured with early detection and early treatment. This is why neonatal screening on inborn errors of metabolism is implemented worldwide. In this study, a cost-benefit analysis was performed on the neonatal screening of phenylketonuria and congenital hypothyroidism in Korea. Methods : This study included 2,908,231 neonates who took the neonatal screening on phenylketonuria and congenital hypothyroidism in Korea from January 1991 to December 2003. From those neonates, the incidence rates of phenylketonuria and congenital hypothyroidism were measured. Furthermore, based on 495,000 babies born in 2002, were calculated and compared the total costs in case when neonatal screening on phenylketonuria and congenital hypothyroidism is implemented, and when not. Results : If the neonatal screening on phenylketonuria and congenital hypothyroidism is implemented, benefits far exceed costs at a ratio of 1.77 : 1 in phenylketonuria, and 11.11 : 1 in congenital hypothyroidism. In terms of wons, the present neonatal screening on phenylketonuria and congenital hypothyroidism will gain us more than 29 billion wons every year. Conclusion : This study only concerns the monetary aspects of the neonatal screening. Therefore, the benefits of the neonatal screening is underestimated by ignoring precious but not measurable values such as quality of life. However, the present neonatal screening on phenylketonuria and congenital hypothyroidism is found to be beneficial and should continue for the good of the nation as well as that of the patients.

• Journal of the Korean Society for information Management
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• v.33 no.4
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• pp.175-199
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• 2016

We analyzed the relationships between the co-authorship network centralities and the research performance indicators with the authors and the number of citations of the papers published for 10 years in Korean library and information science journals. In particular, the research performance indicators were calculated with normal counting and with fractional counting also. As a result of correlation analysis between the variables by setting the different ranges of the author groups to be analyzed according to the number of articles, it was possible to explain the inconsistent results of the previous studies on the correlations between the researchers' citation indicators and their co-authorship network centralities. Overall, the degree of co-authorship activities measured by collaboration coefficient showed no or negatively correlated with research performance. There were statistically significant positive correlations between the centralities and the research performance indicators, but the correlation was not significant in the analysis of the top 30 authors by number of articles.

• The Journal of the Korea Contents Association
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• v.15 no.10
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• pp.387-399
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• 2015

Recently collaboration network is generated to find out experts in their field as potential collaborators in health care sector. In this paper, the co-author network of a National Cancer Center researcher was generated for identifying each researcher's role and collaborative research pattern. The co-author network of 2,437 authors was extracted from 1,194 SCI(E) publications from 2000 to 2010 and author's role was analyzed by author's centrality value. Centrality reflecting only the number of papers and centrality weighted by the paper number, impact factor, and authorship contribution was evaluated. On the comparison with simple degree centrality value and the weighted degree centrality, difference of value was statistically significant(t=11.66, p=0.00). Co-author network considering various variables of the paper provides more objective figure of researcher's role. This suggests that co-author network could be more effective in identifying potential collaborators.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.9 no.1
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• pp.98-104
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• 1998

A 12-year-old girl with a 6 year history of childhood-onset schizophrenia required 2 hospitalizations and long-term clozapine trial due to inadequate responses to combinations of typical neuroleptics and traditional treatments of schizophrenic disorder. On admission, she had continuous auditory and visual hallucinations, persecutory delusion, emotional instability, regression of behaviors including temper tantrums as well as specific developmental delays in learning, language, and motor coordination. The clozapine trial significantly reduced most of the positive symptoms, and facilitated in successful discharge from the hospital. During the 4 year clozapine treatment, no significant adverse reactions were noted, and she returned to a structured school setting with minimal degrees of schizophrenic symptoms. From this clinical experience, we suggest that clozapine might be safe and effective in treating treatment-refractory schizophrenic children.

• Clinical and Experimental Pediatrics
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• v.49 no.2
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• pp.150-156
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• 2006

Purpose : The aims of this study included assessment of molecular-epidemiologic features during an outbreak of colonization of extended spectrum ${\beta}$-lactamase producing Klebsiella pneumoniae(ESBL-KPN) and re-evaluation of their colonized status one year later. Methods : Rectal swab cultures for ESBL-KPN from all hospitalized infants and newly admitted infants were obtained during the outbreak of colonization from July to December, 2000. The pattern of XbaI-digested chromosomal DNA of isolates were analyzed by pulsed-field gel electrophoresis. Weekly rectal swab cultures were obtained during the outbreak until patients were either discharged or decolonized. Patients discharged after being colonized had follow up stool cultures a year later. Results : A total of 80 patients(28.5 percent) were colonized. Of those, 53 whose pulsed-field gel electrophoresis(PFGE) was possible only once, were ESBL-KPN grouped into six cluster clones and 10 single clones : 28 patients(52.8 percent) were colonized with type A, the most common clone, followed by type B in 11 patients(20.8 percent). Of those 12 patients in whom serial PFGE was done more than twice, type A was predominant. Narrowed-down in strains occurred from types A, B, C, D and three single clones at initiation of the study into types A and type B after three months of strict infection control. Among 75 patients(93.7 percent) who were sent home after being colonized, 30 patients were re-called for stool cultures a year later : All of them were decolonized. Conclusion : This study demonstrates the importance of infection control as the diversity of ESBL-KPN strains could be narrowed into fewer strains. Colonization of ESBL-KPN could be reversed upon return to the community.

• Journal of Korean Library and Information Science Society
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• v.42 no.2
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• pp.105-125
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• 2011

This paper grasps about various features of the coauthorship network based on the co-author frequency in the Korean LIS Research Community. This issue includes many topics such as changable aspects of coauthorship network, properties of higher cooperative authors groups. This work is mostly analyzed through a bibliographic analysis of articles which is published from 2000 to 2009(10 years) in Korean Library & Information Science major four journals. The results show three major implications. 1) There is a various structural changes of coauthorship network on the change of the co-author frequency. 2) There are 21 research pairs in the higher cooperative authors groups with the co-author frequency more than five. 3) There seems that any subjective relations between the articles which is produced by 21 research pairs were not clearly presents.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.8 no.1
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• pp.91-95
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• 2005

The familial environment may also play an important role in the epidemiology of HCV infection through vertical and horizontal transmission by infected household members. However, it is still controversial whether familial clustering of HCV occurs. We experienced a case of familial clustering of hepatitis C virus. A 10-year old girl presented with nausea, vomiting and anorexia for a month was diagnosed as hepatitis C. Her mother, grandmother, a maternal aunt and her daughter had contracted with HCV. Her laboratory findings showed AST/ALT 63/122 IU/L, positive anti-HCV Ab and HCV RNA ($3.54{\times}10^5copies/mL$). Pathologic findings of the liver biopsy revealed chronic hepatitis with minimal lobular activity, mild porto-periportal activity and mild portal fibrosis. After treatment with interferon-${\alpha}$ 2b for 6 months, the clinical symptoms and laboratory findings were normalized.

• Journal of Music and Human Behavior
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• v.14 no.1
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• pp.85-108
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• 2017

The purpose of this study was to examine how a therapeutic drumming intervention would impact middle school students with regard to school violence prevention. Participants were all in the third-year class of a middle school in Korea. A school music teacher and a music therapist designed and implemented the program collaboratively, and mainly used dyadic, synchronized, and improvisational drumming based on the Social Emotional Learning core competencies. A total of 65 students participated in a weekly 45-minute program for 10 weeks. Ten participants out of 65 were selected for interviews and the rest of the 55 participants were asked to fill out an open-ended survey. Content analysis of the survey and interviews produced 492 meaningful statements, which were categorized into seven themes: somatic responses to drumming, emotional processing, group cohesion, empathy, relationship with peers, self-esteem, and self-regulation. The findings indicated that dyadic, synchronized, and improvisational drumming may promote prosocial behaviors in students of this age. The author discussed that drumming produces physical input directly from the instruments, which prompts students to identify and empathize with their own or others' emotions. This study therefore suggests that collaborative work between school music teachers and music therapists may positively impact middle school students' prosocial behaviors, as they pertain to school violence in Korea.

• Proceedings of the Korean Society for Information Management Conference
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• 1997.08a
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• pp.75-78
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• 1997

메타데이터 요소집합이란 다양한 형식의 전자문헌 중에서 필요한 정보원을 찾아내는 데 도움이 되는 전자문헌의 가장 기본적인 특징을 기술하기 위한 것이며, 색인보다는 정보량이 많고 공식적인 목록레코드보다는 덜 완전한 레코드를 만들어 이 양극을 조정하려는 것이다. 이의 이점은 다음과 같다. 자동정보원탐색기가 데이터를 수집할 수 있는 형식으로 저자나 출판자가 메타데이터를 만들도록 장려할 수 있으며, 메타데이터레코드의 작성업무를 단순화함으로써 메타데이터요소의 템플릿을 갖는 네트워크출판도구의 개발을 장려할 것이다. 또한 만들어진 메타레코드는 필요하다면 보다 상세한 목록레코드의 바탕이 될 수 있을 것이며, 표준이 된다면 메타데이터레코드는 모든 이용자 집단에게 이해될 수 있을 것이다. 현재 이와 같은 관점에서 활발히 논의되고 있는 Dublin Core 메타데이터 형식을 중심으로 그 현황에 대하여 논한다.

• Journal of Korean Ophthalmic Optics Society
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• v.9 no.1
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• pp.75-79
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• 2004

Some ocular complications were connected to the contamination by the contact lens related. Especially the most cause of ocular complications was a microorganism from several processing of infections. Therefore the patients stopped the contact lens wear immediately by the side effects of ocular pathology. We had analyzed the microorganism from the laboratory. It was identified as mixed growth of the Chryseamonas meningosepticum and Enterobacter sp.