• Journal of the Korea Convergence Society
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• v.12 no.6
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• pp.39-47
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• 2021

The purpose of this study is to analyze the differences among short statured children with growth hormone deficiency, idiopathic, and normal children in order to find the effect of growth hormone deficiency on tooth developmental stage. We classified children diagnosed with short stature at the Pediatrics in Yeungnam University Hospital as subjects due to idiopathic and growth hormone deficiency. We analyzed the relationship between short stature and tooth development through the measuring of oral panorama and body index. Only the eruption of lateral incisors showed significant difference between short statured with growth hormone deficiency and idiopathic. Almost all tooth eruption was significantly delayed on short statured children with growth hormone deficiency compared to average group. In conclusion, short stature children with either growth hormone deficiency or idiopathic were affected not only in their somatic stature but also dental maturity. We look forward to this study presenting basic data for orthodontic therapy.

• Journal of the Korea Convergence Society
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• v.12 no.10
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• pp.89-96
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• 2021

This study is aimed to establish the direction of orthodontic treatment by analyzing the differences in the dental arch development due to the cause of short stature. Dental diagnostic tests were conducted on patients who were diagnosed with short stature. Idiopathic short statured children were classified through the paired sampling based on the age and gender of a short statured children with growth hormone shortage. Control groups were classified using same method as above, after selecting candidates with an arch length of less than 3mm and malocclusion. In conclusion, short statured children with growth hormone shortage or idiopathic had the higher rate of crowding and the small value of overbite compared to normal children. Therefore orthodontic treatment for short statured children needs treatment plan included evaluation for Arch length discrepancy to treat a crowding early. This study will provide important data for successful orthodontic treatment according to the characteristics of dental occlusion of short statured children.

• The korean journal of orthodontics
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• v.40 no.4
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• pp.227-238
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• 2010

Objective: The purpose of this study was to analyze the effect of growth hormone treatment (GHT) on craniofacial growth in children of short stature. Methods: Nineteen untreated children of short stature were referred from the Pediatric Department, Yeungnam University Hospital as a subject group. All subjects had lateral cephalograms taken before, after 1 year and after 2 years of growth hormone treatment. As a reference group, we selected 19 normal children with paired sampling who matched the subjects' age and sex, from the Department of Orthodontics, Kyungpook National University Hospital. Results: Before GHT, anterior cranial base length and upper posterior facial height, posterior total facial height, mandibular ramus length, and mandibular corpus length were significantly smaller in the reference group. In angular craniofacial measurements, saddle angle and mandibular plane angle were larger. SNA and SNB were smaller in the reference group. After two years of GHT, growth hormone accelerated growth in several craniofacial components. The posterior total facial height, the anterior, posterior cranial base length, and the mandibular ramus length were increased. And the difference in mandibular plane angle and ANB values compared with the reference group was decreased. Conclusions: GHT over 2 years leads to a craniofacial catch-up growth tendency, which is pronounced in interstitial cartilage and condylar cartilage.

• Clinical and Experimental Pediatrics
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• v.46 no.4
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• pp.363-369
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• 2003

Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly understood. The aim of this study is to determine whether there are differences in sleep patterns and nocturnal GH secretory profiles between idiopathic short stature children and a normal stature group. Methods : Spontaneous nocturnal GH secretions and sleep patterns were evaluated in 12 prepubertal idiopathic short stature children with normal responses to provocation tests and 9 normal stature controls. Blood samples were taken every 30 minutes from 22:00-06:30 and sleep patterns were analyzed by polysomnography. Results : The mean GH level during sleep was significantly lower in short stature children than in controls. The peak GH level after sleep, coincident with the first slow wave sleep, was lower in the short stature group. The slow wave sleep times of short stature children were decreased compared with those of normal subjects. Conclusion : These results suggest that overnight serial GH sampling is helpful to identify short stature children with subnormal GH secretions, and sleep structure differences may be associated with decreased overnight GH secretions in short stature children.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2006.11a
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• pp.295-298
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• 2006

Experiments in methane-air low strain rate counterflow diffusion flames diluted with nitrogen have been conducted to study the behavior of flame extinction and edge flame oscillation in which lateral conduction heat loss in addition to radiative heat loss could be remarkable at low global strain rates. Onset conditions of edge flame oscillation and flame oscillation modes are also provided with global strain rate. It is seen that flame length is closely relevant to lateral heat loss, and this affects flame extinction and edge flame oscillation. Edge flame oscillations in low strain rate flames are categorized into three: a growing oscillation mode, a decaying oscillation mode, and a harmonic oscillation mode. The regime of flame oscillation is also provided at low strain rate flames.

• Clinical and Experimental Pediatrics
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• v.48 no.8
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• pp.865-870
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• 2005

Purpose : The use of growth hormone(GH) to promote growth in normal short children without classical GH deficiency is controversial. Numerous foreign studies have shown the effects of GH therapy in children with idiopathic short stature(ISS) whereas few has been interested in Korea. Therefore, this study is designed to investigate the effects of GH therapy on ISS by observing correlations and changes among various growth parameters such as, insulin-like growth factor-I(IGF-I) and insulin-like growth factor binding protein-3(IGFBP-3). Methods : This study was conducted retrospectively with 15 children with ISS in Chungbuk National University Hospital in Korea. Mean age was $11.44{\pm}2.81$ and the children were treated with 0.66 IU/kg/wk dosage of GH for 1 or 2 years. Also, the growth parameters before and after the GH therapy were observed. Results : Height standard deviation score(HT-SDS) was increased from $-1.85{\pm}0.70$ to $-1.58{\pm}0.56$ at 1 year and to $-1.21{\pm}0.37$ at 2 years after GH therapy. Predicted adult height standard deviation score(PAH-SDS) was also increased from $-2.10{\pm}0.52$ to $-1.67{\pm}0.59$ at 1 year, and to $-0.96{\pm}0.60$ at 2 years. Serum IGF-I and IGFBP-3 levels were significantly increased after 1 year and marginally increased after 2 years of GH therapy. Conclusion : It is concluded that GH therapy has growth promoting effect. The significant increase in IGF-I and IGFBP-3 levels during the GH therapy suggests that IGF-I and IGFBP-3 are useful predictors of response to the use of GH therapy. It is expected that larger patient samples would provide more reliable information about the effect of GH therapy.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.1
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• pp.117-124
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• 2021

Among growth disorders, 'Short Stature' can be improved through rapid diagnosis and treatment, and for that, it is important to detect early'Short Stature'. It is recommended to measure the height steadily for early detection of 'Short Stature' and checking the kid's growth process, but existing height measurement methods have problems such as time and space limitations, cost occurrence, and difficulty in keeping records. So in this paper, we proposed an 'Development of Kid Height Measurement Application based on Image using computer vision' method using smart phones, a medium that is highly accessible to people. In images taken through a smartphone camera, the kid's height is measured using algorithms from OpenCV, a computer vision library, and the measured heights were printed on the screen through 'a comparison graph with the standard height by gender and age' and 'list by date', made possible to check the kid's growth process. It is expected to measure height anytime, anywhere without time and space limitations and costs through this proposed method, and it is expected to help early detection of 'Short Stature' and other disorder through steady height measurement and confirmation of growth process.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.52-52
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• 1992

cisplatin 자체는 용혈작용이 고농도에서 얼었는데 반하여 호중구 자극상등액에서는 저농도에서 높은 용혈작용을 나타내 신장독성이 호중구 활성화에 기인할 것이라는 가능성을 시사하였다. In vitro에서 대부분의 활성산소 제거제는 세포독성 억제효과가 있었으며 in vivo 투여시에도 합성 항산화제인 BHA 등은 혈청 BUN, creatinine치의 현저한 감소를 나타내 좋은 신장독성억제 효과를 보여주었다.

• 한국정보교육학회:학술대회논문집
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• 2004.01a
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• pp.513-521
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• 2004

현재 초등학생용 컴퓨터 수업에서 그래픽 수업을 위한 초등학생 교육용 소프트웨어와 컨텐츠가 부족한 것이 현실이다. 매주 컴퓨터 수업을 하고 있으나 교과서에서 그래픽 관련 단원 수업은 거의 미미한 수준이다. 또한 초등학교 저학년 아동들의 발달단계 및 흥미를 고려한 그래픽 프로그램의 부재로 아동들이 학습을 하는데 어려움을 겪고 있다. 저학년 아동들을 위한 컴퓨터 그래픽 에디터가 필요하며 컴퓨터 그래픽에 관련된 단원을 아동들에게 가르치고 있으나 단순한 흥미수준의 몇 시간의 수업으로 끝나고 있는 실정이다. 본 연구에서는 초등학교 저학년을 위한 그래픽 에디터의 개발과 이러한 단편적인 지도를 보다 체계적인 지도 내용을 마련하여 초등학교 저학년 컴퓨터 그래픽 활용능력을 신장시키고자 한다.

• The Korean Journal of Rheology
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• v.5 no.1
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• pp.23-33
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• 1993

저밀도폴리에틸렌과 나일론6의 블렌드가 용융압출기의 사용에 의해 제조되었다. 제 조된 비상용 블랜드의 유변학적, 형태학적 분석을 통하여 이들사이의 상관관계를 조사하였 다. 전단속도, 계면장력, 용융점도, 분산상의 농도들에 대한 분산상의 크기의 의존성을 평가 하였다. 한편 신장유동에 의한 모폴로지 변화를 조사하기 위하여 기제조된 블렌드를 사용하 여 용융방사를 하였다. 이러한 방식실험으로부터 본연구에 사용된 저밀도 폴리에틸렌과 나 일론6는 분산상과 연속상의 신장점도의 상대적 크기에 무관하게 피브릴화가 되어 방사 연신 비의 증가에 의해 매우 가는 분산된 피브릴을 얻을수 있었다.