• Title/Summary/Keyword: 저선량방사선

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Usefulness Evaluation of Low-dose CT for Emphysema : Compared with High-resolution CT (폐기종에 대한 저선량 CT의 유용성 평가: 고해상도 CT와 비교)

  • Lee, Won-Jeong
    • Journal of radiological science and technology
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    • v.39 no.3
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    • pp.329-336
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    • 2016
  • The purpose of this study was to evaluate the usefulness of low-dose CT (LDCT) for emphysema compared with high-resolution CT (HRCT). Measurements of radiation dose and noise were repeated 3 times in same exposure condition which was similar with obtaining HRCT and LDCT images. We analysed reading results of 146 subjects. Six images per participants selected for emphysema grading. Emphysema was graded for all 6 zones on the left and right sides of the lungs by the consensus reading of two chest radiologists using a 4-point scale. Between the HRCT and LDCT images, diagnostic differences and agreements for emphysema were analyzed by McNemar's and unweighted kappa tests, and radiation doses and noise by a Mann-Whitney U-test, using the SPSS 19.0 program. Radiation dose from HRCT was significantly higher than that of LDCT, but the noise was significantly lower in HRCT than in LDCT. Diagnostic agreement for emphysema between HRCT and LDCT images was excellent (k-value=0.88). Emphysema grading scores were not significantly different between HRCT and LDCT images for all six lung zones. Emphysema grading scores from LDCT images were significantly correlated with increased scores on HRCT images (r=0.599, p < 0.001). Considering the tradeoff between radiation dose and image noise, LDCT could be used as the gold standard method instead of HRCT for emphysema detection and grading.

Hematological Change in Mice Injected with Radiosensitizer and Irradiated with High-dose Radiation (방사선 증감제를 투여한 마우스에 고 에너지 방사선 조사 후 혈액학적 변화에 관한 연구)

  • Ji, Yeon-Sang;Dong, Kyung-Rae;Jung, Myo-Young;Park, Yong-Soon;Dong, Cha-Bun;Ryu, Young-Hwan
    • The Journal of the Korea Contents Association
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    • v.9 no.12
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    • pp.357-363
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    • 2009
  • The current population of elderly is increasing and the with an extended average lifespan, the frequency of cancerous occurrences have also increased, with these increases and the increase in radiotherapy for cancer patients, recognitions of harm and importance have become known. This article was known tumor treatment of patients with hematopoietic disorder by doing a comparative study on the changes in blood cells caused by the acute effects of trace dose to high dose of radiation exposed to mice. According to the sensitizer injection may give rise to harm to the components of peripheral blood. This material needs to be considered when for treating tumor patients and the risks of hematopoietic harm and believe that radiation therapy will be reasonable.

Application of Low-Dose CT for Screening of Lung Disease (폐질환의 선별검사를 위한 저선량 전산화 단층촬영의 적용)

  • Lee, Won-Jeong;Choi, Byung-Soon;Park, Young-Sun;Seon, Jong-Ryul;Bae, Seok-Hwan
    • Journal of radiological science and technology
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    • v.32 no.2
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    • pp.129-140
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    • 2009
  • As CT has been increasingly used as an accurate screening tool for lung disease, radiation dose becomes an important issue for both radiographers and patients. Many researches have been done for a low-dose CT as a screening tool for early detection of asymptomatic lung diseases. From those studies, it has been reported that chest dose rate from the low-dose CT is considerably lower than from standard CT. The patient dose is determined by scanning parameters such as kVp, mAs, pitch, scan time and the radiation risk of lung in screening examination may not be negligible. Herein, we suggest that Low-dose CT is useful as a screening tool in routine clinical practice on the basis of published articles, but further study is necessary because Low-dose CT has poor sensitivity and specificity for screening early stage of lung cancer according to the results of the studies. This article is to provide a brief overview of the screening examinations by Low-dose CT.

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A Study on Mice Exposure Dose for Low-dose Gamma-irradiation Using Glass Dosimeter (유리선량계를 이용한 저선량 방사선의 마우스 피폭선량 연구)

  • Noh, Sung Jin;Kim, Hyo Jin;Kim, Hyun;Jeong, Dong Hyeok;Son, Tae Gen;Kim, Jung Ki;Yang, Kwangmo;Nam, Sang-Hee;Kang, Yeong-Rok
    • Journal of Radiation Protection and Research
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    • v.40 no.4
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    • pp.202-210
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    • 2015
  • The low dose radiation is done for a long period, thus researchers have to know the exact dose distribution for the irradiated mouse. This research has been conducted in order to find out methods in transmitting an exact dose to mouse in a mouse irradiation experiment carried out using $^{137}Cs$ irradiation equipment installed in the DIRAMS (Dongnam Institution of Radiological & Medical Sciences) research center. We developed a single mouse housing cage and shelf with adjustable geometric factors such as distance and angle from collimator. The measurement of irradiated dose showed a maximal 42% difference of absorbed dose from the desired dose in the conventional irradiation system, whereas only 6% difference of the absorbed dose was measured in the self-developed mouse apartment system. In addition, multi mice housing showed much difference of the absorbed dose in between head and body, compared to single mouse housing in the conventional irradiation system. This research may allow further research about biological effect assessment for the low dose irradiation using the self-developed mouse apartment to provide more exact doses which it tries to transmit, and to have more reliability for the biological analysis results.

A Study on Characteristic of Glass Dosimeter According to Graded Change of Tube Current (유리선량계의 단계별 관전류량 변화에 따른 특성연구)

  • Son, Jin-Hyun;Kim, Seong-Ho;Mun, Hyun-Jun;Kim, Lyun-Kyun;Son, In-Hwa;Kim, Young-Jun;Min, Jung-Whan;Kim, Ki-Won
    • Journal of radiological science and technology
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    • v.37 no.2
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    • pp.135-141
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    • 2014
  • This study was evaluated the linearity and reproducibility according to dose, and reproducibility according to delay time by changing tube current amount (5 mAs, 10 mAs, 16 mAs, 20 mAs, 25 mAs, 32 mAs respectively, which are low energy radiations) using Glass Dosimeter (GD) and piranha semiconductor dosimeter which are used for measuring exposure dose. Measurements of radiation dose were performed using external detector of piranha 657 which is multi-function QA device (RTI Electronic, Sweden). Conditions of measurement were 80 kVp, SSD 100 cm and exposure region is $10cm{\times}10cm$. Glass dosimeter was exposed to radiation. Twenty-four glass dosimeters were divided into six groups (5 mAs, 10 mAs, 16 mAs, 20 mAs, 25 mAs, 32 mAs respectively), then measured. This study was resulted by measuring the linearity and reproducibility according to change of tube current in low energy field. In dose characteristic of GD, this study could be useful as previous study with regard to dose characteristic according to change of tube voltage in low energy field.

Endobronchial Brachytherapy for Malignant Airway Obstruction: Low Dose Rate Versus High Dose Rate (악성 종양에 의한 기도폐쇄시 내기관지 근접치료 : 저선량 치료 대 고선량 치료의 비교)

  • Cho, Young-Kap
    • Radiation Oncology Journal
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    • v.14 no.2
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    • pp.123-128
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    • 1996
  • Purpose : This is a retrospective study to compare the Palliation rates, survival rates and complications of low dose rate and high dose rate endobronchial brachytherapy in the management of malignant airway obstruction. Materials and methods : Forty three consecutive patients with malignant airway compromise from primary or metastatic lung tumors were treated with low dose rate(LDR) endobronchial Iridium-192 insertion(21 patients) between October 1988 and June 1992, and high dose rate(HDR) endobronchial brachytherapy(22 patients) between August 1992 and April 1994 with palliative aim Flexible fiberoptic bronchoscopy under fluoroscopic control was utilized in all 91 procedures. Twenty seven LDR Procedures delivered a dose of 5-7.5 Gy to a 1.0 cm radius respectively. Results : Subjective and objective responses to treatments were evaluated on follow-up examinations by clinical examination, chest x-rays and CT scan of the chest on some patients. Fifteen of 21 LDR patients and 19 of 22 HDR Patients showed subjective improvement in terms of better breathing and less Productive cough as well as complete disappearance of hemoptysis. Objective improvement on chest x-rays and CT scan of the chest had been demonstrated on 8 LDR Patients and 10 HDR patients. Conclusion : The technique of LDR and HDR endobronchial brachytherapy is simple and well tolerated procedure with minimal morbidity It Provides excellent palliation by keeping airway Patent in these short life-spanned patients.

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저선량 방사선 영향과 발현암의 인과성 문제

  • Lee, Jae-Gi
    • Radioisotope journal
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    • v.15 no.3
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    • pp.78-92
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    • 2000
  • 낮은 선량의 방사선피폭으로 인한 건강 위해의 여부에 대하여 과학적 현황을 고찰하였다. 선량과 영향 사이에 문턱 없는 선형비례 모델(LN-T모델)에 대해 역학적, 수학적, 방사선생물학적 측면의 긍정적 논리와 호메시스, 적응반응, 통계적 관점의 비판적 논거를 대비하여 평가하였다. 방사선 피폭이력자에게 발현한 확률적 영향 특히 백혈병을 포함한 암에 대해 그 질환의 방사선 인과성 판단에 대한 애로와 접근 방향을 논의하였다. 객관적인 평가 지표의 하나로 기인확률(PC)을 적용하되 근로자에 대한 제도적 배려 등 고려할 사항을 논의하였다.

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