• Journal of Periodontal and Implant Science
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• v.31 no.4
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• pp.651-659
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• 2001

후박추출물은 치주병인균에는 항균효과가 있고, 치은섬유아세포에는 세포독성이 적은 것으로 알려져 있으며 홍아씨 추출물은 골아세포를 활성화시키는 효과가 있어 골조직재생에 효과가 있는 것으로 알려져 있다. 이 실험의 목적은 비글견에 인위적으로 치주염을 유도하고 후박추출물과 홍화씨추출물의 혼합물을 투여함으로써, 이 두 가지 혼합물이 치주염 진행에 예방효과가 잇는지, 또, 치료효과가 있는지 알아보는 것이다. 후박과 홍화씨를 구입하여 에탄올에서 추출하여 정제하고 진공상태에서 건조시켜 농축하였다. 후박추출물과 홍화씨 추출물을 1:5의 질량비로 혼합하고 250㎎씩 캡슐에 넣었다. 비글견의 상하악 소구치와 하악 제1대구치를 8주 동안 철사와 견사로 결찰하여 치주염을 유발하였다. 8주 후에, 실험군 비글견에게는 미리 후박추출물과 홍화씨추출물 혼합물을 매 12시간마다 하루에 1,500㎎ 씩 12주 동안 투약하였다. 대조군 비글견에는 투약을 하지 않았다. 투약을 시작한 후에 치은지수, 부착수준을 매 4주마다 측정하였다. 매 4주마다 치주낭에서 페이퍼포인트를 이용하여 혐기성세균과 호기성세균을 채취, 배양하여 각각의 집락 수를 세었다. 그 결과 실험군의 치은지수는 8주, 12주에서 대조군보다 유의하게 낮았고(p<0.05)), 임상적으로도 상당한 치은염의 개선을 보였다. 실험군의 혐기성세균 집락수는 감소하여 4, 8, 및 12주에서 대조군에 비해 유의하게 낮았고(p<0.001), 호기성 세균 집락수는 4, 8, 및 12주에서 대조군에 비해 유의하게 낮았다.(p<0.05)이 실험 결과, 후박 추출물과 홍화씨 추출물 혼합물이 치주질환의 예방 및 치료에 이용되어질 수 있을 것으로 생각된다.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.4
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• pp.657-661
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• 2005

Various chemotherapeutic agents have been recommended for pulpotomy of primary teeth, and there are formocresol, ferric sulfate, and calcium hydroxide. Of those, formocresol has fixation effect of pulp tissue and high clinical success rate, so it is most commonly used agent. But formocresol has strong cytotoxic effects, thus many articles reported displacement and loss of permanent successor, amelogenesis imperfecta, mutation by general absorption, possibility of cancer induction. Recently, it has been reported that leakage by imperfect temporary sealing when FC-soaked cotton was inserted into the root canal caused necrosis of surrounding tissues. and that necrosis of alveolar bone related to the use of excessive formocresol. In this case, 2nd primary molar of upper left jaw was treated using formocresol in local clinic, but extracted because of lasting pain. Furthermore, symptoms didn't disappear so patient was refered to us. The patient was 8-year-old male, had foul odor from oral cavity and circular alveolar bone necrosis around the permanent successor' crown. Thus sequestrectomy was operated and observed through 19 months after operation, we found normal root development of permanent successor but no complete regeneration of alveolar bone defect and attached gingiva. Lesion of periodontal tissues by formocresol is irreversible, so we have to confirm the indication in using formocresol and pay attention to complete temporary sealing.

• Clean Technology
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• v.18 no.3
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• pp.229-249
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• 2012

At present, global warming and depletion of fossil fuels have been one of the big issues which should be solved for sustainable development in the future. CCS (carbon capture and sequestration) technology as the post $CO_2$ reduction technology has been considered as a promising solution for global warming due to increased carbon emission. However, the environmental and ecological effects of CCS have drawn concerns. There are needs for noble post reduction technology. More recently, CCU (carbon capture and utilization) Technology, which emphasizes transforming carbon dioxide into value-added chemicals rather than storing it, has been attracted attentions in terms of preventing global warming and recycling the renewable carbon source. In this paper, various technologies developed for carbon dioxide conversion both in gas and liquid phase have been reviewed. For the thermochemical catalysis in gas phase, the development of the catalytic system which can be performed at mild condition and the separation and purification technology with low energy supply is required. For the photochemical conversion in liquid phase, efficient photosensitizers and photocatalysts should be developed, and the photoelectrochemical systems which can utilize solar and electric energy simultaneously are also in development for more efficient carbon dioxide conversion. The energy needed in CCU must be renewable or unutilized one. CCU will be a key connection technology between renewable energy and bio industry development.

• Korean Journal of Optics and Photonics
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• v.17 no.6
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• pp.507-513
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• 2006

In this paper, we propose an improved image encryption and fault-tolerance decryption method using phase wrapping and phase encoding in the frequency domain. To generate an encrypted image, an encrypting key which denotes the product of a phase-encoded virtual image, not an original image, and a random phase image is zero-padded and Fourier transformed and its real-valued data is phase-encoded. The decryption process is simply performed by performing the inverse Fourier transform for multiplication of the encrypted key with the decrypting key, made of the proposed phase wrapping method, in the output plane with a spatial filter. This process has the advantages of solving optical alignment and pixel-to-pixel mapping problems. The proposed method using the virtual image, which does not contain any information from the original image, prevents the possibility of counterfeiting from unauthorized people and also can be used as a current spatial light modulator technology by phase encoding of the real-valued data. Computer simulations show the validity of the encryption scheme and the robustness to noise of the encrypted key or the decryption key in the proposed technique.

• Journal of Marine Bioscience and Biotechnology
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• v.1 no.3
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• pp.213-217
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• 2006

We evaluated the potential of major components of Phellodendri cortex to inhibit the activities of CYP2D6 and p-glycoprotein. The abilities of berberine, palmatine, limonin, and rutaecarpine to inhibit CYP2D6-mediated dextromethorphan O-demethylation and calcein AM accumulation were tested using human liver microsomes and L-MDR1 cell, respectively. Berberine strongly inhibited CYP2D6 isoform activity, whereas limonin and reuaecarpine did not. The $IC_{50}$ value of berberine was reduced after preincubation with microsomes in the presence of NADPH generating system, suggesting that berberine is a mechanism based inhibitor. In addition, all chemicals tested, didn't show inhibitory effect on p-glycoprotein activity. These results suggest that berberine has potential to inhibit CYP2D6 activity in vitro. Therefore, in vivo studies investigating the interactions between berberine and CYP2D6 substrates are necessary to determine whether inhibition of CYP2D6 activity by berberine is clinically relevant.

• Nuclear industry
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• v.37 no.9
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• pp.58-90
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• 2017

'공포의 값비싼 대가(The High Cost of Fear)'는 공개된 자료 중 동료 평가를 마친 최신의 자료와 간단한 계산 방법을 통해 한국의 탈원전 정책이 가져올 경제적, 환경적 영향을 분석한 보고서이다. 우리는 탈원전 정책이 다음과 같은 영향을 미칠 것으로 예측한다. ${\cdot}$천연가스 구매에만 최소 매년 100억 달러의 비용이 들 것이다. 이는 한국 평균임금인 연소득 29,125달러를 받는 일자리 343,000개에 해당하는 금액이다. ${\cdot}$비용의 대부분은 연료 수입에 사용될 것이며, 한국의 무역 수지가 악화될 것이다. ${\cdot}$한국의 부족한 재생에너지 자원을 고려할 때, 상당한 양의 화석 연료를 추가로 사용하게 될 것이다. ${\cdot}$LNG 발전소가 석탄 발전소를 대체하지 못하고 원자력발전소를 대체하면서 대기 오염으로 인한 조기 사망자 수가 증가할 것이다. ${\cdot}$한국의 전도유망한 원전 수출 산업이 아예 붕괴되거나 큰 타격을 입을 것이다. ${\cdot}$평균적 미국 자동차의 연간 주행거리를 기준으로 150만대에서 270만대의 미국 자동차가 배출하는 배기가스의 양만큼 연간 탄소 배출이 증가할 것이고, 한국은 파리기후협정에서 약속한 탄소 배출 감축 목표를 달성할 수 없게 된다. 본 보고서는 현재 계획된 탈원전 정책의 역사적 사회적 배경을 분석하여 다음과 같은 결론을 도출하였다. ${\cdot}$'그린피스(Greenpeace)', '지구의 친구들(Friends for the Earth)' 등 막대한 자금 지원을 받는 해외 환경단체들은 탈원전 거짓 정보의 근원이며, 이들은 저렴하고 풍부한 에너지라는 개념을 반대한다. ${\cdot}$후쿠시마 원전 사고와 그 여파의 주된 원인은 일본 원자력산업계의 오만과 원자력에 대한 과장된 집단 공포이다. ${\cdot}$반핵 진영의 논리에는 산업계와 정부에 대한 불신과 원자력, 방사선에 대한 몰이해가 반영되어 있다. ${\cdot}$반핵 진영은 후쿠시마 사고를 2014년 한수원 납품 비리 사태의 심각성을 과장하는 데 사용하고 있다. 2014년의 비리 사태는 한국 원자력 규제기관의 독립성을 증명했으며, 2016년의 경주 지진은 2011년 후쿠시마에서 쓰나미와 노심 용융을 초래한 동일본 대지진의 1/350,000의 크기밖에 되지 않는다. 본 보고서는 한국과 타국가의 반핵 운동이 주는 교훈을 다음과 같이 정리하였다. ${\cdot}$어떠한 국가도 에너지 자원 최빈국인 프랑스나 한국 같은 국가조차도 탈원전 '전쟁'에서 자유롭지 않으며, 이는 전 세계적으로 원자력산업이 쇠퇴하는 원인이다. ${\cdot}$원자력산업계, 정부, IAEA 등은 한국과 세계 여러 국가에서- 문화적, 제도적, 재정적 원인으로 원자력산업의 보호와 확대라는 목표를 달성할 수 없다. ${\cdot}$원자력산업을 구하기 위해서는 새로운 비전과 새로운 제도, 그리고 새로운 리더십이 필요하다. ${\cdot}$원자력의 근원적이고 혁신적인 비전 원자력 인본주의(atomic humanism)에 대한 재조명이 필요하다. ${\cdot}$원자력을 지키고 대중과 소통하기 위해 과학 연구단체, 대학교, 사단법인, NGO 등의 새로운 기관들을 후원해야 한다. ${\cdot}$공포를 조장하는 반원전 세력에 맞서 공포를 극복해야 하고, 대중의 공포를 극복해왔던 다른 기술들의 사례에서 교훈을 얻어야 한다.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.18 no.1
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• pp.135-143
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• 1996

The aim of this study was to evaluate bone promotion of bioreabsorbable guided tissue regeneration for generating new bone adjacent to osseointegrated implants in dogs. Third premolars were extracted in dgo mandibles. Cylindrical HA-coated implants were placed into extracted sockets in dogs. And test sites were protected by $GUIDOR^{(R)}$ matrix barrier. But control sites were not protected by membrances. The sites were examined clinically, radiologically, and histologically after 1, 2, and 4 months to assess bone regeneration. The results obtained were as foolows : 1. There were the good healing and the stability of $GUIDOR^{(R)}$ matrix barrier in experimental site during the healing period. 2. Complete resorption of $GUIDOR^{(R)}$ matrix barrier was clinically observed about 4 months postoperatively. 3. The woven bone changed to mature bone with a normal cortical plate and mature, resting periosteum after 4 months. 4. In experimental site, there was a significantly greater bone promtion than observed in control site. 5. $GUIDOR^{(R)}$ matrix barrier was useful for the preparation of immediate dental implants.

• The Journal of the Convergence on Culture Technology
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• v.6 no.4
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• pp.385-389
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• 2020

The medical drama has developed into a story centered on 'people', raising viewers' sympathy. The story of the drama is the true life story of doctors, patients and families. It is also a story that reminds me of 'a little special day of our ordinary people'. And the song played and sung by five characters in the drama became a factor that stimulates nostalgia and increases immersion. The highest viewer rating was 14.1%, and 51,584 blogs alone were registered. According to the big data analysis, the related words were 'Wise OST', 'Album Name', 'Artist Name', 'Two Hours in a row', 'Record', 'Remake', 'OST Revealed', 'Advertisement Revenue', 'Playlist', 'Aroha' and 'Cho Jung-seok'. The commercialization of medical dramas includes 'Sales of Drama OST Albums', 'Organizing Online Live Concerts (PPL in Advertising)', 'Publishing Piano Music', 'Picture of People-Oriented Photography', 'Making Music Video Editing Drama Highlight', 'YouTube Upload Profits', 'Mask' and 'Disinfectant'. it is predicted that the touching story of Corona 19 and the charming humanity will unfold. The limitations of the research will require analysis of various works by genre and attempts to analyze consumer values by industry.

• Journal of Dental Rehabilitation and Applied Science
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• v.34 no.1
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• pp.32-38
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• 2018

Purpose: The purpose of present study was to retrospectively analyze the survival rate of narrow diameter implant less than 3.6 mm by initial stability and radiographic measurements. Materials and Methods: In total, 24 patients who received 38 narrow diameter implants (${\leq}3.6mm$ in diameter, ${\geq}7mm$ in length) were enrolled in this retrospective study. The cumulative survival rate was calculated and various factors were investigated according to the implant platform diameter, body diameter, length, position, concomitant use of guided bone regeneration in implant placement and final prosthesis type. Initial stability was investigated with implant stability quotient (ISQ) value. The mesial and distal marginal bone level (MBL) change was calculated with radiography. Results: The overall survival rate was 92.11%. Mean ISQ value and MBL change of survival implants was 66.26 and $0.14{\pm}0.31mm$, respectively. None of the implants with platform diameters larger than the body diameter failed. Conclusion: In conclusion, the findings of present study suggest that narrow diameter implant could be predictable treatment in narrow alveolar ridge.

• Journal of The Korean Society of Grassland and Forage Science
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• v.24 no.1
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• pp.21-24
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• 2004

To determine lethal temperature of alfalfa (Medicago sativa L. cv Vernal) at heat-stressed conditions, seedlings grown in a small pots for 4 weeks were subjected to different temperature regimes of heat treatment. No apparent demage was observed when the plants were treated at 45, 50 or $60^{\circ}C$ for 1 h. Heat treatments at 60 and $65^{\circ}C$ for 1 h, several plants were withered and showed damage symptom on their leaves. When the plants were exposed to $70^{\circ}C$ for 1 h, most of leaves were severely withered, but it was not lethal conditions for the whole plants. By contrast, most of plants were died within one day after heat treatment at $80^{\circ}C$ for 1h. Furthermore, plants exposed to $80^{\circ}C$ for 50 min were also died within 7 days. It was found that new shoots were regenerated from the plants that had been treated at $80^{\circ}C$ within 45 min. These results indicate that heat treatment at $80^{\circ}C$ for 50 min is an optimum condition to distinguish the lethality of alfalfa plants. Simple viability assay system established in this study will be useful fer selection and characterization of heat-tolerant transgenic alfalfa plants.