• Journal of the korean veterinary medical association
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• v.45 no.8
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• pp.746-757
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• 2009

국립수의과학검역원과의 공동연구과제(소 아까바네병, 츄잔병, 아이노 바이러스혼합불활화 예방약 산업화)에 의해 실시한 시험을 통하여 소 아까바네병, 츄잔병, 아이노 바이러스병에 대한 예방약인(소 츄잔병, 아까바네병, 아이노병 불활화 혼합오일백신) 면역원성 시험 및 야외에서의 적용시험 등을 실시한 결과를 요약하면 다음과 같다. 1. 혼합오일백신의 기니픽에 대한 면역원성 시험에서 아까바네 바이러스, 아이노 바이러스 및 츄잔 바이러스에 대한 중화항체가는 시험백신을 3주 간격 2회 접종한 시험구가 무접종 대조구에 비하여 높게 나타났다. 2. 혼합오일백신의 야외농장 3곳의 육성우에 대한 면역원성 시험에서 시험백신을 2회 접종 후 아까바네 바이러스의 항체가는 평균 102배, 115배 및 134배이였으며, 아이노 바이러스의 항체가는 평균 8배, 24배 및 27배로 나타났고, 츄잔 바이러스의 경우에는 3곳의 농장에서 평균 30배, 46배 및 172배로 나타났다. 3. 야외농장 2곳에서 혼합오일백신을 임신우에 2회 접종하였을 때, 중화항체가는 아까바네 바이러스가 평균 64배와 93배를 나타내었고, 아이노 바이러스의 중화항체가는 평균 70배와 96배, 츄잔 바이러스의 중화항체가는 평균 20배와 20배로 나타났다. 4. 혼합오일백신은 임신우에 대한 공격접종시험에서 시험백신을 3주 간격으로 2회 접종 후 3주째의 중화항체가는 아까바네 바이러스가 128$\sim$256배이었고, 아이노 바이러스는 64$\sim$256배로 나타났고, 츄잔 바이러스는 8$\sim$32배이었다. 공격 접종 후 부검 전의 중화항체가는 아까바네 바이러스가 16$\sim$128배로 나타났고, 아이노 바이러스는 32$\sim$128배였으며, 츄잔 바이러스는 4$\sim$16배였다. 혼합오일백신을 임신우에 3주 간격 2회 접종한 뒤 공격접종하여 채혈한 혈청의 면역원성이 무접종 대조군에 비하여 방어효과가 우수하였다. 5. 3롯트의 시험백신을 선정하여 2$\sim$7$^{\circ}C$의 냉암소에 보존하면서 보존 기간별(제조당시, 6개월, 12개월, 15개월, 18개월)로 특성시험, 무균시험 및 안전시험을 실시한 결과, 전 보존기간에 마우스 및 기니픽에 대한 안전성이 인정되었으며, 보존기간별로 시험백신의 기니픽에 대한 면역원성 시험을 실시한 결과, 기니픽의 중화항체가는 15개월까지 지속되는 것으로 나타났다.

• Journal of Digital Convergence
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• v.11 no.6
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• pp.235-244
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• 2013

This research was performed to investigate the effects of participation in aqua exercise on blood composition and vascular compliance of mentally retarded persons. The targets of this research consisted of a control group of 12 people and an aqua exercise group of 12 people after selecting 24 mentally retarded males and aqua exercise group carried out an exercise program for 60 minutes per day and five days a week for 9 weeks. Weight, body fat percentage, blood composition and vascular compliance were measured in a preliminary inspection and the same items were measured in a post-inspection. The results of this measurement were as follows. Firstly, aqua exercise group showed a significant decrease in weight and body fat percentage (p<.05). Secondly, for blood composition, aqua exercise group showed a notable decrease in Total-Cholesterol, Triglyceride, and LDL-Cholesterol (p<.05) and a significant increase in HDL-Cholesterol (p<.05). Thirdly, aqua exercise group showed a notable increase in blood composition for both upper limbs and lower limbs (p<.05). Taken these results together, it was considered that a participation of mentally retarded persons in aqua exercise would prevent adult diseases and would have an affirmative influence on improvement of the quality of life.

• Journal of Digital Contents Society
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• v.12 no.2
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• pp.253-262
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• 2011

IT skills might be just a product for people without disabilities; however it can be "another sense" that is able to give the disabled the same social abilities as non-disabled people. Library services are necessary to help disabled people have access to information. The effectiveness of the library services for the disabled depends on the level and the size of library. If 10% of the total domestic population couldn't participate in their social activities, it must be a huge individual at the same time national loss. This paper will look into supporting technologies and services for the reading disabled through literature researches and visiting domestic and international libraries. Based on this analysis, this paper suggests development plans for enhancing domestic situation. We are sure that our suggestions can contribute to give a long-term service development strategy for improving the reading disabled people's information accessibility.

• Journal of KIISE:Computing Practices and Letters
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• v.14 no.3
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• pp.321-325
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• 2008

Void areas(holes) as an inevitable phenomenon exist in geographic routing of wireless sensor networks, because the unpredictable and harsh nature application environment or uneven energy consumption. Most of the existing schemes for the issue tend to construct a static detour path to bypass a hole. The static detour path may lead to uneven energy consumption of the nodes on the perimeter of the hole; thus it may enlarge the hole. At the same time, traffic would concentrate on the peripheral node of the hole; thus the nodes on the perimeter of the hole tend to be depleted quietly. In previous work, we have proposed a hole geometric model to reduce the energy consumption and packet collisions of the nodes on the hole boundary. This scheme, however, still has the static detour path problem. Therefore, we extend the previous work by constructing a dynamic detour path hole geometric model for wireless sensor networks in this paper. The location of hole detour anchors is dynamically shifted according to Gaussian function, just generating dynamic hole detour paths.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1983.05a
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• pp.18.1-18
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• 1983

In 1923 Pierre-Robin first described the triad of micrognathia, glossptosis and high-arched or cleft palate. Respiratory distress is not an uncommon occurrence and requires prompt and appropriate treatment. The syndrome occurs once in approximately 50,000 births. Although the etiology of the syndrome is obscure, it is known that the syndrome probably results from a primary deficiency early in fetal life of mandibular development. The symptoms of airway obstruction develop as the base of the tongue falls posteriorly and approximates the posterior pharyngeal wall because of micrognathia, and is aggravated when the infant is in the supine position. The problems of mild airway obstruction can be solved by keeping the infant in the prone position. In case there are feeding difficulties, prompt glossopexy should be preformed as airway is aggravated, but tracheostomy is best avoided. There is some forms of glossopexy including Douglas operation, the insertion of Kirschner wire and Duhamel suture. We identified micrognathia, glossoptosis and high-arched palate in a 2-month-old infant who was brought to our hospital with complaints of dyspnea and feeding difficulties, and we reports this case, since we think this infant whom we observe after tracheostomy because we found Duhamel suture could not relieve the symptoms of airway obstruction as Pierre-Robin syndrome.

• Anxiety and mood
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• v.7 no.1
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• pp.16-21
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• 2011

Objective : Depressive symptoms often coexist with other anxiety disorder symptoms. Furthermore, an anxiety disorder that is comorbid with a depressive disorder results in more severe symptoms and a poorer outcome prognosis. To understand the construct of depressive symptoms in anxiety disorder, this study investigated the factor structure of the Beck Depression Inventory among outpatients with anxiety disorders. Methods : All data were from psychiatric department outpatients at a university-affiliated hospital. We conducted a principal component analysis using data from 194 outpatients with DSM-IV anxiety disorders and calculated goodness-of-fit-indices. Results : Exploratory factor analysis revealed a four factor structure--Cognitive-affective symptoms (Factor 1), Somatic symptoms (Factor 2), Self-reproach (Factor 3), and Hypochondriasis/indecisiveness (Factor 4)--and a 57% total variance. This four-factor model demonstrated an acceptable level of model fit, and it fit better than did a three-factor solution from the literature on depressive disorder. Conclusion : This study's results suggest a difference in the construct of self-reported depressive symptoms in anxiety disorders. These findings also support a dimensional approach to studying anxiety and depression. Further studies may benefit from including comorbid depressive disorder and its influence on anxiety disorders.

• Journal of Oriental Neuropsychiatry
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• v.33 no.4
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• pp.453-462
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• 2022

Objectives: The purpose of this clinical case study was to report the effect of Korean medicine treatment on a stroke patient with cognitive impairment, dysuria, and gait disturbance. Methods: The patient was treated with Korean medicine, including herbal medicine, acupuncture, moxibustion, and cupping. We administered the Korean version of the Mini-Mental Status Examination (MMSE-K) Global Deterioration Scale (GDS) and Manual Muscle Test (MMT) and investigated the frequency of nocturia to evaluate the effectiveness of the treatment and improvement in symptoms. Results: After Korean medicine treatment, the patient's symptoms were significantly improved. according to the MMSE-K, frequency of nocturia, and MMT results. Conclusions: This clinical case study suggests that Korean medicine treatment, including Wuchasinkihwan-gagam could be an effective treatment for stroke patients with symptoms of cognitive impairment, dysuria, and gait disturbance.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.174-176
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• 2022

In this paper, we present a mobile application for 'personalized customized learning' for children with articulation disorders using an artificial intelligence (AI) algorithm. A dataset (Data Set) to analyze, judge, and predict the learner's articulation situation and degree. In particular, we designed a prototype model by looking at how AI can be improved and advanced compared to existing applications from the UX/UI (GUI) aspect. So far, the focus has been on visual experience, but now it is an important time to process data and provide a UX/UI (GUI) experience to users. The UX/UI (GUI) of the proposed mobile application was to be provided according to the learner's articulation level and situation by using CRNN (Convolution Recurrent Neural Network) of DeepLearning and Auto Encoder GPT-3 (Generative Pretrained Transformer). The use of artificial intelligence algorithms will provide a learning environment with a high degree of perfection to children with articulation disorders, thereby enhancing the learning effect. I hope that you do not have any fear or discomfort in conversation by improving the perfection of articulation with 'personalized and customized learning'.

• The Korean Journal of Nuclear Medicine
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• v.28 no.1
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• pp.44-51
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• 1994

It is known that the normal His-Purkinje system provides for nearly synchronous activation of right (RV) and left (LV) ventricles. When His-Purkinje conduction is abnormal, the resulting sequence of ventricular contraction must be correspondingly abnormal. These abnormal mechanical consequences were difficult to demonstrate because of the complexity and the rapidity of it's events. To determine the relationship of the phase changes and the abnormalities of ventricular conduction, we performed phase image analysis of $^{99m}Tc$-RBC gated blood pool scintigrams in patients with intraventricular conduction disturbances (24 complete left bundle branch block (C-LBBB), 15 complete right bundle branch block (C-RBBB), 13 Wolff-Parkinson-White syndrome (WPW), 10 controls). The results were as follows; 1) The ejection fraction (EF), peak ejection rate (PER), and peak filling rate (PFR) of LV in gated blood pool scintigraphy (GBPS) were significantly lower in patients with C-LBBB than in controls ($44.4{\pm}13.9%$ vs $69.9{\pm}4.2%,\;2.48{\pm}0.98$ vs $3.51{\pm}0.62,\;1.76{\pm}0.71$ vs $3.38{\pm}0.92$, respectively, p<0.05). 2) In the phase angle analysis of LV, Standard deviation (SD), width of half maximum of phase angle (FWHM), and range of phase angle were significantly increased in patients with C-LBBB than in controls ($20.6{\pm}18.1$ vs $8.6{\pm}1.8,\;22.5{\pm}9.2$ vs $16.0{\pm}3.9,\;95.7{\pm}31.7$ vs $51.3{\pm}5.4$, respectively, p<0.05). 3) There was no significant difference in EF, PER, PFR between patients with the Wolff-parkinson-White syndrome and controls. 4) Standard deviation and range of phase angle were significantly higher in patients with WPW syndrome than in controls ($10.6{\pm}2.6$ vs $8.6{\pm}1.8$, p<0.05, $69.8{\pm}11.7$ vs $51.3{\pm}5.4$, p<0.001, respectively), however, there was no difference between the two groups in full width of half maximum. 5) Phase image analysis revealed relatively uniform phase across the both ventricles in patients with normal conduction, but markedly delayed phase in the left ventricle of patients with LBBB. 6) In 13 cases of WPW syndrome, the site of preexcitation could be localized in 10 cases (77%) by phase image analysis. Therefore, it can be concluded that phase image analysis can provide an accurate noninvasive method to detect the mechanical consequences of a wide variety of abnormal electrical activation in ventricles.

• Journal of Oral Medicine and Pain
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• v.31 no.4
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• pp.365-373
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• 2006

This study suggested correction of excessive mouth opening or maximum occlusal contact to analyse occlusal contact time, occlusal contact number and force through evaluation of occlusal pattern in policemen with temporomandibular disorders. The community of policemen influence on temporomandibular disorder's development and progress due to other condition of mouth opening and maximal occlusal contact. Repeated training or changes of usual life style may cause imbalance of stomatognathic system including the masticatory muscle, then develop or aggravate pain of temporomandibular joints and associated structures. This study uses T-scan II system(Tekscan Co., USA) for evaluation on occlusal pattern may influence temporomandibular disorders, and then the subjects take a sensor at 20 mm opening for maximal occlusal contact force. The policemen with temporomandibualr disorders get more long time on maximum contact timing, more short on end contact timing, and more force on end contact force than general society's. So they get closure of mouth with more short time and more force, then transfer remaining load to temporomandibular joint. There are no statistically significances between affected side and occlusal pattern of occlusal contact time and force. There are Left -right dental arch imbalances seems on Rt. dental arch if affected side is right and Lt. dental arch if affected side is left. In above results, It's worth due consideration that policemen with temporomandibular disorders get more smooth mandibualr movement and less force on maximal occlusal contact position.