• Title/Summary/Keyword: 장기 추적연구

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Cohort Study for the Effect of Chronic Noise Exposure on Blood Pressure among Male Workers (만성적 소음노출이 혈압에 미치는 영향에 대한 코호트연구)

  • Cha, Tae-Joon;Kim, Jang-Rak;Kang, Wee-Chang;Yaang, Seung-Rim;Lee, Choong-Ryeol;Yoo, Cheol-In;Lee, Ji-Ho
    • Journal of Preventive Medicine and Public Health
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    • v.35 no.3
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    • pp.205-213
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    • 2002
  • Objective : Whether exposure to chronic noise induces an increase in blood pressure, or the development of hypertension, has not been established. A cohort study was performed to identify the effects of chronic noise exposure on blood pressure. Methods : 530 males working at a metal manufacturing factory in Busan, Korea were enrolled for the study. They were monitored for 9 consecutive years, from 1991 to 1999, with an annual health check-up. The subjects were divided into 4 groups, which were determines by noise level categories(NLC) according to noise intensity ; NLC-I: office workers, exposed to noise a level below 60dB(A) ; NLC-II: field technical supporters or supervisors, frequently exposed to workplace noise, wearing no hearing protection device; NLC-III: workers, exposed to workplace noise below 85dB(A), wearing ear plugs or muffs; NLC-IV: workers, exposed to workplace noise over 85 dB(A), wearing both ear plugs and muffs. Results : After controlling possible confoundens, such as baseline age, smoking, alcohol intake, exercise, family history of hypertension, systolic(SBP) of diastolic blood pressure(DBP) and changes in BMI (body mass index), the pooled mean for the systolic blood pressures, over the duration of the study period, were 3.8mmHg, 2.0mmHg and 1.7mmHg higher in NLC-IV, NLC-III NLC-II groups, respectively, than in the NLC-I group. There were no significant differences in the diastolic blood pressures between the groups. Conclusion : This study suggests that chronic noise exposure increases systolic blood pressure independently, among male workers.

A Study on the establishment of Korean maritime boundaries (입체시를 활용한 변화지역 자동 추적 알고리즘 개발)

  • Kim, Kam-Lae;Lee, Ho-Nam;Cheong, Hae-Jin;Cho, Won-Woo
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2007.04a
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    • pp.115-119
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    • 2007
  • 종중복도 60%이상, 횡중복도 30%이상 촬영되어지는 항공영상과 스테레오 촬영이 가능한 위성영상은 도화에 사용되는 입체시를 이용하여 영상(Stereo Aerial Image) 자체를 화면상에 입체적으로 구현하여 건물의 높이 정보 판독 및 해당 지역상에서 년도별 변화지역을 판독하는 일련의 업무 수행에 있어 중요한 자료로 활용하고 있지만 장기간의 작업시간, 작업에 대한 정확성에 취약점을 나타내고 있으며, 이는 행정업무의 효율성 저하요인을 발생하고 있다. 이에 본 연구에서는 이러한 항공사진 및 위성영성의 촬영상의 특성을 활용하여 영상 매칭 DEM을 활용한 높이정보의 변화와 영상 정합을 통한 변화지역 판독을 자동화 하는 시스템을 구현하였다. 시스템 구현을 위해서 개발 언어로 Visual C++을 사용하였으며, 개발된 알고리즘에 대한 평가 수행을 위해 사용자가 직접 입체 판독 및 분석을 수행할 수 있도록 편광 모니터를 사용하여 판독 시스템을 추가적으로 개발하였다.

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Estimation of evapotranspiration of groundwater using isotope tracer(${\delta}^{18}O,\;{\delta}D$) in Yuseong spar district, Daejeon (동위원소(${\delta}^{18}O,\;{\delta}D$)를 이용한 유성지구에서의 증발산량 추정)

  • Jo Seong-Hyeon;Mun Sang-Ho;Yun Uk
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2006.04a
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    • pp.360-364
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    • 2006
  • 물수지 분석을 통해서 유역의 수문순화 체계를 이해하기 위해서는 무엇보다 필요한 인자가 증발산량이다. 장기간에 걸쳐 연구유역에서 수소와 산소 동위원소를 이용하여 증발산량을 산정하였다. 물 분자를 이루는 이상적인 추적자인 수소와 산소 강우를 풍수기($4{\sim}10$월)와 갈수기(11월$\sim$3월)로 나누어 수소와 산소 동위원소 조성을 강수량 가중 평균치를 구하고 이 값을 지하수의 수소와 산소 동위원소 조성 값과 비교하여 증발산량을 산정한 것이다. 이러한 시도는 증발산량의 산정이 단순한 경험식이나 열전도 가정식이 아닌 실측했다는데 의의가 있다.

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Cryotherapy for Two Cases of Recurrent Laryngeal Papillomas (재발성 성문부 유두종 환자의 냉동치료)

  • Lee, Joon-Kyoo;Lee, Dong-Hoon
    • Korean Journal of Head & Neck Oncology
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    • v.28 no.1
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    • pp.19-23
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    • 2012
  • 목 적 : 액체 질소를 이용한 냉동 치료는 피부 사마귀 치료에 널리 사용되어왔다. 본 연구에서는 재발성 성문부 유두종 환자에 대해 냉동 치료를 시행하여 그 치료 결과를 알아보고자 하였다. 방 법 : 냉동치료 전에 재발성 유두종으로 확진 되었고, 다른 호흡기에는 병변이 없었던 환자를 대상으로 하였다. 결 과 : 냉동 치료의 국소적, 전신적 합병증 및 부작용은 없었다. 그러나, 성문부 유두종은 냉동 치료 후 각각 3개월과 2년 후에 재발하였다. 결 론 : 냉동치료는 초기에는 성문부 유두종 병변의 치료에 효과가 있으나, 장기적인 효과는 떨어졌다. 향후 더 많은 증례와 추적관찰이 필요할 것으로 생각된다.

위성자료를 이용한 미계측 유역의 장기유출모의 평가 -임진강 유역을 중심으로

  • Kang, Keon Kuk;Jeung, Se Jin;Lee, Suk Ho;Kim, Byung Sik
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.453-453
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    • 2015
  • 미계측 유역에서의 수문 예측은 유역의 다차원 시공간에서 일어나고 있는 수문학적 기능에 대한 깊은 이해와 성찰을 요구한다. 유역면적의 2/3가 미계측 지역인 임진강 유역은 북한지역과 중첩하고 있어 관측자료가 불충분 하고 소량의 관측자료가 존재하더라도 기후변화로 인해 환경이 변화하기 때문에 미계측 지역 연구에 적당하다. 이에 따라 수문학적 반응을 예측할 수 있도록 비접촉 비파괴적인 도구를 이용하여 수집된 자료를 통해 미계측 유역에 대한 정확한 신뢰성 구축을 마련할 필요가 있다고 판단된다. 신뢰성 구축을 위한 방법으로는 현장답사 및 항공사진에 비하여 넓은 지역을 한번에 관측할 수 있는 Landsat TM 영상을 이용하여 북한의 지형과 토지피복특성 등을 구축하고, 준분포형 모형인 SLURP를 이용하여 소유역으로 구분 된 ASA의 하도 추적을 통해 전체유역의 출구지점 유출량을 산정하였다. 또한 예측 불확실성을 감소시키기 위해 wamis에서 제공하는 GIS Data와 위성영상의 Data를 비교하여 분석하였다. 그 결과 미계측 지역의 불확실성을 최소화 시킬 수 있는 비교 분석이 가능하였다.

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Effectiveness of the Assessment of the Depressive Symptomatology and Social Functioning as Rated by the Client's Significant Other (친지에 의한 클라이언트의 우울증상 및 사회기능 측정의 유효성 연구)

  • Park, Sun-Young
    • Korean Journal of Social Welfare
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    • v.52
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    • pp.143-170
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    • 2003
  • This study investigated the effectiveness of the assessment of psychosocial treatment outcome in symptomatology and social functioning as rated by the depressed client's significant other in explaining the client's symptomatology and social adjustment at 6 and 12 month follow-up period after the 16-week psychosocial treatment was terminated. The data were drawn from the National Institute of Mental Health Treatment of Depression Collaborative Research Program of the U.S. Significant others of depressed clients have rarely participated in the assessment of treatment outcome, although they are major participants of the clients' daily life and have meaningful opportunities to observe the clients' functioning in different social situations. Thus, this study aimed to examine the explanatory power of the significant others' outcome assessment in depressive symptomatology and social functioning for the long-term outcome in symptomatology and social adjustment. The outcome measures used by the significant others were actual performance, expected performance, gap between actual and expected performance, and symptomatology drawn from the Katz Adjustment Scale-Relatives Form. Three major findings were: (1) in general, the posttreatment assessment by the significant other demonstrated stronger explanatory power of the follow-up status than the assessment rated at pretreatment in all of the four outcome domains; (2) the significant other's assessment of actual and expected performance at both pre- and posttreatment demonstrated significant explanatory power of the follow-up status in symptomatology and social/leisure and work adjustment; and (3) the significant other's assessment of social functioning at pretreatment improved the explanatory power over and above the explanation by symptomatology in the follow-up status of social/leisure and work adjustment; however, at posttreatment, symptomatology improved the explanation over and above social functioning more frequently in predicting both symptomatology and social/leisure and work adjustment. These findings suggest the effectiveness of the measures of symptomatology and actual and expected performance as assessed by significant others. The results imply that mental health professionals and researchers need to involve the depressed client's significant other in the treatment and make good use of their contribution in treatment planning and further intervention in the follow-up period to prevent relapse.

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Effectiveness of Sensory-Feedback Ankle Training on Motor Functions in Hemiparetic Patients (시지각을 이용한 발의 감각되먹임 적용이 편마비 환자의 운동기능에 미치는 영향)

  • Seo, Dong-Kwon;Lee, Dong-Yeop
    • Proceedings of the KAIS Fall Conference
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    • 2010.11b
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    • pp.595-598
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    • 2010
  • 본 연구의 목적은 뇌졸중으로 인한 만성 편마비 환자를 대상으로 발에 시지각 자극을 적용하여 균형과 보행에 관한 운동기능에 미치는 효과를 알아보고자 하였다. 6개월 이상 된 편마비 환자 16명이 연구에 참여하였고, 무작위로 실험군(EG) 10명과 대조군(CG) 10명으로 구분하였다. 두 군 모두 기본적인 물리치료를 적용하였고 실험군은 정적균형도구인 Tetrax Multiple System을 이용하여 발목에 감각되먹임 시지각 자극을 매회 30분, 4주간 주 3회 실시하였다. 운동 중재 전과 후의 운동기능에 해당하는 균형(TUG), 보행(DGI)을 측적하여 본 연구의 효과를 비교하였다. 실험군에서 정적 균형, TUG, 그리고 동적 균형지수(DGI) 지수는 중재 전후 통계적으로 유의한 차이를 나타냈고(p<.05), 실험, 대조군간 전후의 변화율에서도 유의한 차이가 나타났다(p<.05). 대조군에서는 DGI 만 중재 전후 통계적으로 유의한 차이가 나타났다. 순수하게 유산소 운동만을 실시하였다. 통계처리 방법으로 전 후 차이를 검증하기 위하여 대응표본 t 검정을 실시하였고 대조군과의 차이 검증을 위하여 독립표본 t 검정을 실시하였다. 모든 통계적 유의수준은 0.05로 하였다. 본 연구에서는 편마비 환자에게 흥미를 촉진하고 운동 기능 회복의 효과를 강화할 수 있는 감각 되먹임이 동반된 시지각 자극을 적용하여 균형 및 보행기능의 향상을 얻을 수 있었고, 차후 연구는 장기간의 추적 관찰 연구가 지속되어야 하고 발목 뿐만 아니라 다른 관절에서의 비교연구가 필요할 것이다.

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A Clinical Analysis on the Restoration of Sinus Rhythm Following Mitral Valve Surgery (승모판 수술 후 동율동 회복에 관한 임상분석)

  • 백완기;심상석;김현태;조상록;진성훈
    • Journal of Chest Surgery
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    • v.32 no.4
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    • pp.347-352
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    • 1999
  • Background: The atrial fibrillation in patients with mitral valvular heart disease is frequently converted to sinus rhythm after the mitral valve surgery. This sinus restoration implies an important meaning in that it not only helps postoperative convalescence in patients with unstable hemodynamics but also reduces the rate of postoperative thromboembolism. Material and Method: We retrospectively analyzed 184 patients who received mitral valve surgery from June 1986 to December 1996 to investigate the trend of rhythm change following mitral valve surgery and thus to clarify the predisposing factors of postoperative sinus rhythm conversion and its maintenance. Result: The sinus rhythm was restored after the operation in 54 out of 139 patients with atrial fibrillation preoperatively(38.8%). However, the atrial fibrillation recurred in 41 patients at the time of discharge showing a recurrence rate of 75.9 percent. The mean duration of sinus rhythm in patients with eventual atrial fibrillation recurrence was 8.2${\pm}$5.9 days. Only 15 patients were in sinus rhythm at the time of late follow-up with the mean follow-up period of 84.4${\pm}$34.7 months. While the age, duration of symptoms, duration of atrial fibrillation, left atral size, and pulmonary artery pressure were thought to be the predisposing factors for sinus conversion after the operation, only the duration of atrial fibrillation and ejection fraction were considered risk factors for the recurrence of the atrial fibrillation following sinus conversion. Conclusion: This study suggests that the early operation is mandatory for the satisfactory result regarding postoperative rhythm. Moreover, additional operative measure in adjunct to the intervention of mitral valve should be considered for the maintenance of restored sinus rhythm as reflected by high postoperative recurrence rate of atrial fibrillation.

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Development of Biotelemetry Method by Combining the SSBL Method and the Pinger Synchronizing Method (1) - Design and production of system - (SSBL 방식과 핑거동기 방식을 조합한 바이오텔레메터리 방식의 개발 (1) -시스템의 설계 및 제작 -)

  • 박주삼;고탁창언
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.39 no.3
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    • pp.218-229
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    • 2003
  • A new biotelemetry method that the installation and the treatment of equipment is convenient and the instantaneously detailed location of the fish attached the pinger is able to track comparatively easily was developed. The receiving system in this biotelemetry method was advanced for track the detailed behavior of the fish by the miniature tracking pinger, because it was a burden to fish to add the pinger with the water temperature and the pressure sensor. By combining of the super short base line (SSBL) method to detect the direction of pinger and the pinger synchronizing method to measure the range from receiving transducer to pinger, the three dimensional locations of fish to the receiving transducer is gotten instantaneously. The receiving system is devised to realize the high precision or wide detection range by application of the basic design method for receiving system of biotelemetry developed by the present authors and the hydrophone array configuration. The measurement distance error in the pinger synchronizing method is minimized through the correction of which the deviation of transmission pluse period of pinger is caused by changing water temperature. A prototype system which is able to track the instantaneously detailed location of the fish by the SSBL and pinger synchronizing biotelemetry (SPB) method was produced.

Diamond-Blackfan anemia: long-term follow-up of six cases (Diamond-Blackfan 빈혈: 6예 장기간 추적관찰보고)

  • Son, Young Jun;Baek, Hee Jo;Kook, Hoon
    • Clinical and Experimental Pediatrics
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    • v.51 no.11
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    • pp.1211-1216
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    • 2008
  • Purpose : Diamond-Blackfan anemia (DBA) is a rare heterogeneous genetic disorder of infancy and early childhood. It is characterized by red cell aplasia, congenital anomalies, and a predisposition to cancer. Corticosteroids and red cell transfusions are the mainstays of therapy. We describe our experience of 6 cases of DBA that were encountered over a period of 16 years. Methods : Medical records of 6 patients diagnosed to have DBA and admitted to the Chonnam National University Hospital between 1992 and 2008 were retrospectively reviewed. Results : Three patients were males. The age at diagnosis ranged from 3 to 18 months (median, 5.5 months). Heart defects were observed in 4, polydactyly in 2, and strabismus in 1 patient. The median number of transfusions was 3 (range, 2-8). All patients responded to initial treatment with steroids and had a hemoglobin level ${\geq}9g/dL$ with a median of 12.5 days (range, 7-22 days). Three patients are currently not receiving steroid therapy. A minimum dose of oral prednisolone (<5 mg per day) was required to maintain hemoglobin ${\geq}9mg/dL$ in 3 cases. Red cell transfusion was infrequently required in 1 patient. In the median follow-up of 14 years, there was no development of malignancy. No significant side effects of steroids were found, except for short stature in 2. Conclusion : The majority of DBA patients achieved complete response and under maintenance therapy with low dose of steroids. Close observation is needed to monitor steroid side effects, cardiac function, and development of malignancy. A nation-wide survey is necessary to further characterize this rare disease in Korean children.