• Applied Biological Chemistry
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• v.27 no.3
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• pp.146-150
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• 1984

Changes of weight loss and quality in 3 different apple cultivars and four storage conditions were investigated for 6 month storage. Weight loss changes in the pilot scale low temperature storage $(^{\circ}C)$ could be predicted with linear equations. Quality defects were remarkably increased at 5% of weight loss in all cultivars and storage conditions. It was possible to predict by linear equations the quality of apples by measuring acidity and texture highly correlated to the sensory scores.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.40 no.7
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• pp.590-600
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• 2012

In this research, generalized sizing methods were studied that can be applied to an aircraft which uses solar cell or fuel cell as energy sources. To consider multiple propulsion systems and energy resources, multiple power paths were modeled and the weight of consumable and non-consumable energy was reflected in the weight change calculation for each mission segments. In the constraint analysis, power to weight ratio was selected instead of thrust to weight ratio and used in the sizing process of balancing power and energy.

• Journal of Ginseng Research
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• v.30 no.4
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• pp.199-205
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• 2006

It was investigated that how the periodic exposure to heat environment, and the treatment of korean white and red ginseng extracts had effects on the weight, diet uptake, blood components, organ weight, and the lipid peroxidation of liver in male S.D. rats. In the result of experiments using rats, chronic heat environment for 7 days at $38^{\circ}C$, 5 hrs per day, induced significant decrease of an average increase rate of body weight, but diet uptake was not affected clearly. In heat environment, the number of red blood cells and hemoglobin were not changed, but the number of white blood cells was significantly increased. The liver weight against body weight was decreased in rats. Also, MDA contents, related to lipid peroxidation, were remarkably increased in rat liver by heat environment. These physiological changes were attenuated by treatments of white and red ginseng extracts before and after exposure to heat environment, particularly in growth rate and lipid peroxidation of liver in rats. Also, red ginseng extracts had a better effect, though it was not that significant, than the white ginseng on the inhibition of lipid peroxidation and the weight change of liver. Although the investigation on the effective components and the study on the activity changes of associated materials are needed to perform, these present results imply that Korean ginseng may contribute to protection of body homeostasis against drastic climate changes.

• Journal of Life Science
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• v.9 no.2
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• pp.182-193
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• 1999

In order to establish basic data of SAMP6 as an animal model for osteoporosis, present study has been designed to concentrate on the various biological aspects of SAMP6 such as growth index, hematology, blood biochemistry, biochemical characteristics, and bone and cortical thickness. Investigation period was for 15 months (3 months to 18 months of age) and biological characteristics have been examined throughout the study period. The results were summarized as follows : Decreased body weight of male SAMP6 was noticed from 7 months of age compared to from 18 months of age in female. Although there were no significant differences in organ weights, generally those of male mice were greater than those of females, especially in liver, kidney and lung. According to the analysis of blood biochemistry and hematology, the number of leukocytes in male mice was greater than that of female mice. There was a decrease in bone thickness in both male and female mice starting around from 7 months of age. Peak cortical thickness index was noticed at 5 months of age in both sexes. In femur, the highest $Ca^{2+}$ content for both sexes was noticed at 5 months of age, whereas the highest P$^{3+}$ content was noted at the age of 5 and 7 months in male and female mice, respectively. The contents of both elements were gradually decreased with age after peaks for both sexes. In summary, SAMP6 mice in KRICT colony show osteoporotic characteristics starting from 5 to 7 months of age, suggesting that at least 5 months of old animals should be used for studying the mechanism of osteoporosis or screening anti-osteoporosis drugs. This study also suggests that the cortical index thickness, $Ca^{2+}$ and P$^{3+}$ contents, and alkaline phosphatase activities can be used as indexes for drug screening.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.168-168
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• 1993

신의약품의 생식독성 평가를 위해서는 타독성시험의 경우와 마찬가지로 NOEL (no observed effect level) 의 범위를 확립하는 일이 매우 중요한데, 이것은 정상치(control values), 자연발생소견 (spontaneous findings)등과 비교함으로서 가능하다. SPF 동물을 이용한 독성실험은 선진국에 비해 역사가 짧을 뿐만 아니라 아직 풍부한 기초자료가 확립되지 않아 외국의 자료들을 인용하고 있는 실정이다. 본 연구에서는 랫트를 이용한 최기형 시험결과의 효율적인 평가를 위해 생식독성 검사항목의 기초 데이타를 확립하였다. 이를 위해 화학연구소 실험동물육종실에서 입수한 SPF: Sprague- Dawley 랫트를 이용해 1989년부터 1991년까지 실시한 생식독성 시험의 대조준 데이타 (체중, 사료소비량, 장기중량, 제왕절개성적, 외표, 내부장기 및 골격검사성적, 자연분만군 시험성적 등)를 분석하였다. 요늑의 발현율, 견인력 시험결과 및 피모발생 일평이 외국의 타 연구기판 데이타와 다소 차이를 나타냈을 뿐 기타 항목들은 거의 일치하는 정상치를 보였다. 아울러 기형, 변이, 골화지연 등으로 구분되는 골격소견의 합리적인 평가를 위해 랫트 골격소견 평가기준을 정했고 최기형 시험에서 얻어지는 데이터의 통계처리 방법을 보완, 체계화하였다. 본 연구결과는 Sprague-Dawley 계통 랫트외 생물학적 정외는 물론 효율적인 생식독성 평가를 위한 소중한 기초 자료가 될 것으로 사료된다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.17 no.2
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• pp.77-84
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• 1988

The effect of chronic ethanol consumption on the concentration of minerals in tissues and serum was studied in growing broiler chicks. Four different groups of the chicks were fed mixtures of 0(control), 1,2 and 3% ethanol and water respectively for 7 weeks. Body weight gain in 1% ethanol group and liver weight in 3% ethanol group were significantly higher than those of control. Mg, K, Mn, and Zn concentrations in liver were higher in ethanol groups than those in control. In ethanol groups, femoral muscle Mg level was increased while its Na concentration was decreased. The concentrations of Ca, Mg and Na in serum were higher in 3% ethanol group than those in control, 1 or 2% ethanol groups. In femur, Zn and Fe levels in 1% ethanol group and Mn concentration in 2 or 3% ethanol groups were increased. But its weight, length, and ash content were not affected by ethanol intake.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.42 no.1
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• pp.47-58
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• 2014

In this research, the initial sizing of a HALE(High Altitude Long Endurance) UAV which uses solar power and hydrogen fuel cell as an alternative energy was performed. Instead of a wing box type, a glider type was chosen since it is relatively easy to get a data thanks to many researches abroad. Maximum takeoff weight is around 150Kg and the propulsion system is composed of motor, propeller, solar cell, and hydrogen fuel cell which can be recharged through electrolysis. Maximum takeoff weight was estimated as aspect ratio, wing span, wing area change while considering energy balance of required energy which is necessary for flight during the entire day and available energy which can be taken from the solar cell.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.253-253
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• 1994

영지와 구름버섯의 원형질체 융합 균주 F-1의 배양 균사체로 부터 열수추출한 분획 Fr.I을 DEAE-cellulose ion chromatography와 gel filtration chromatography를 통하여 분획 Fr.II, III, IV,로 분리 정제하였다. Sarcoma 180에 대한 종양억제율을 검사한 결과 Fr.IV는 68.73%로 가장 우수하였으며 동계 복수암에 대한 수명 연장 효과도 140 %의 유의적인 결과를 얻었다. 면역 관련 장기의 중량에 대한 영향을 실험한 결과 정상군에 비해 간, 비장 및 흉선의 중량을 증가시켰고, 마우스 암세포에 대한 직접적인 세포독성 작용을 보이지 않았으나 면역 실험을 실시한 결과, 마우스에서 용혈반 형성세포수를 1,36배 증가시켰으며 암이식군에서 감소된 T lymphocyte활성을 정상수준까지 회복시켰고 또, macrophage의 superoxide anion 분비를 2.25배 증가시켰다. 이로써 이 항암 성분은 면역세포를 활성화시켜 항암 효과를 나타냄을 의미한다. Fr.IV히 분자량은 7.9$\times$$10^4$ dalton이고 75,57%의 다당체와 4.47%의 단백질로 이루어졌으며 그 다당체는 주로 glucase, xylose와 mannose로 구성된 heteropolysaccharide이었으며 그 단백질은 Alanine과 Valine을 위시한 15종의 아미노산을 함유하고 있음이 확인되었다.

• Magazine of the Korean Society of Agricultural Engineers
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• v.42 no.6
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• pp.90-97
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• 2000

In this study, the variation of unit weight and unconfined compressive strength were investigated, calcium carbonate, quicklime, portland cement, 19mm length monofilaments and fibrillated fiber were used as reinforcement materials. And calcium chloride was added to cement and calcium carbonate reinforced soil mixture in order to accelerate setting and hardening speed. It appears that unit weight is highest in calcium carbonate reinforced soil mixture with mixing rate of 9%. According to increasing the amount of fiber in soil mixture, the unit weight decreased. It shows that the more the amount of monofilament fiber is added in soil mixture, the higher the compressive strength is, but the compressive strength is decreased in fibrillated fibrillated fiber added soil mixture with more than 1.0% of mixing rate.

• Journal of KSNVE
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• v.14 no.2
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• pp.26-34
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• 2004

현재 철도는 기술의 발전과 함께 초고속 대량수송, 정시성, 안전성, 에너지효율성 및 친환경성 등의 장점을 가지는 새로운 교통수단으로 재조명되고 있다. 국내에서도 고속철도 개통과 G7고속열차의 개발 등으로 철도기술은 제 2의 도약기에 들어서고 있으며, 특히 도로교통망의 포화로 인해 철도건설수요가 계속적으로 증가할 것으로 기대되는데, 기존 수송량의 흡수 및 장기적인 관점에서 철도교통망의 확장을 도모하기 위해서는 열차의 중량화와 고속화가 제반기술의 발전과 함께 지속적으로 추진될 것으로 판단된다. 그러나 이러한 차량의 중량화와 고속화는 실질적으로 선로 주변에 발생되는 소음 및 진동의 크기를 증가시키게 되는데, 최근 들어 소음 및 진동관련 환경기준의 강화와 민원의 증가 등으로 인해 친환경적인 측면에서 적극적인 소음 진동 저감대책의 수립과 관련 기술의 적용이 요구되고 있는 상황이다.(중략)