• The Korean Journal of Applied Statistics
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• v.31 no.4
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• pp.517-528
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• 2018

We provide R scripts to detect outliers in multivariate data and visualization. Detecting outliers is provided using three approaches 1) Robust Mahalanobis distance, 2) High Dimensional data, 3) density-based approach methods. We use the following techniques to visualize detected potential outliers 1) multidimensional scaling (MDS) and minimal spanning tree (MST) with k-means clustering, 2) MDS with fviz cluster, 3) principal component analysis (PCA) with fviz cluster. For real data sets, we use MLB pitching data including Ryu, Hyun-jin in 2013 and 2014. The developed R scripts can be downloaded at "http://www.knou.ac.kr/~sskim/ddpoutlier.html" (R scripts and also R package can be downloaded here).

• Journal of the Korean Geotechnical Society
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• v.17 no.3
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• pp.15-23
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• 2001

탄소성 캡 모델의 중요한 장점은 여러 가지 다공체의 전체적인 축차 및 체적의 비선형 상호거동을 동시에 다룰 수 있음에 있다. 그러나 대부분의 캡 모델이 가진 문제점중의 하나는 세 개의 독립적인 항복면이 불연속으로 연결되어 있음으로부터 기인된다. 본 연구에서는 이러한 항복면 사이의 연결점에서의 탄소성 접선 계수는 특이점이 되고 수치해석상 잠재적인 어려움을 내재하고 있음을 나타내고 이러한 문제의 해결방안의 하나로 세 개의 항복면이 연속적으로 만나는 새로운 탄소성 캡 모델을 제시하였다. 본 논문에서는 모델의 증분형태의 구성식 및 새로운 응력을 구하기 위한 활동 항복면의 결정을 판단하는 알고리즘이 제시되었다. 동반 논문에서는 내재적인 응력적분 및 일관적인 접선계수를 유도하였고 예제계산들을 수행하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2020.05a
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• pp.107-108
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• 2020

최근 센서데이터 활용 영역이 넓어지면서 데이터 분석 서비스가 활성화되고, 분석을 용이하게 할 수 있는 환경으로 진화하고 있다. 이에 따라 센서데이터의 신뢰성 보장이 필요하다. 신뢰성을 갖는 환경모니터링을 위해서는 센서로부터 수집된 환경 데이터의 분포 및 값을 살펴본 후 데이터가 표현하는 현상을 더 잘 이해하고, 센서 및 센서데이터에 대한 잠재적인 특이점을 발견을 선행하여야 한다. 이를 위해 EDA를 통해 수집된 센서 값을 시각화하고 분석에 주어진 데이터의 개별 속성의 특징 및 상관관계를 도출한다. 본 연구의 EDA 분석 결과는 센서데이터의 신뢰성을 평가하기 위해 사용한다.

• Investigative Magnetic Resonance Imaging
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• v.14 no.1
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• pp.69-73
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• 2010

Cerebral fat embolism (CFE) is a rare, albeit potentially lethal complication of long-bone fractures. All trauma patients who are initially lucid and subsequently experience mental status deterioration should undergo immediate evaluation of possible CFE. In the present case, magnetic resonance imaging (MRI) was the most sensitive technique for the diagnosis of CFE, particularly the use of diffusionweighted images (DWI). The authors present this case to report a pathophysiologybased interpretation of the MR characteristics and treatment of CFE.

• KSBB Journal
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• v.25 no.3
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• pp.215-222
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• 2010

Monogenic diseases are resulted from modifications in a single gene of human cells. Because their treatment with pharmacological medicine have a temporary effect, continuous nursing care and retreatment are required. Gene therapy, gene targeting and induced pluripotent stem cell (iPSC) are considered permanent treatment methods of them. In gene therapy, however, retroviral vectors that have potential toxicity caused by random insertion of harmful virus are used as vehicles for transferring genetic materials. On the other hand, gene targeting could replace and remove the modified gene though homologous recombination (HR) induced by site-specific endonucleases. This short review provides a brief overview on the recently tailored endonucleses with high selectivity for HR.

• The KIPS Transactions:PartD
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• v.13D no.7 s.110
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• pp.857-866
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• 2006

Performance of an image retrieval system is usually very low because of the semantic gap between the low level feature and the high level concept in a query image. Semantically relevant images may exhibit very different visual characteristics, and may be scattered in several clusters. In this paper, we propose a content based image rertrieval approach which combines region based image retrieval and a new relevance feedback method using adaptive clustering together. Our main goal is finding semantically related clusters to narrow down the semantic gap. Our method consists of region based clustering processes and cluster-merging process. All segmented regions of relevant images are organized into semantically related hierarchical clusters, and clusters are merged by finding the number of the latent clusters. This method, in the cluster-merging process, applies r: using v principal components instead of classical Hotelling's $T_v^2$ [1] to find the unknown number of clusters and resolve the singularity problem in high dimensions and demonstrate that there is little difference between the performance of $T^2$ and that of $T_v^2$. Experiments have demonstrated that the proposed approach is effective in improving the performance of an image retrieval system.

• Food Science of Animal Resources
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• v.24 no.4
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• pp.349-354
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• 2004

Stress-susceptible pigs have been known as the porcine stress syndrome (PSS), swine PSS, also known as malignant hyperthermia (MH), is characterized as sudden death and production of poor meat quality such as PSE (pale, soft and exudative) meat after slaughtering. PSS and PSE meat cause major economic losses in the pig industry. A point mutation in the gene coding for the ryanodine receptor (RYR1) in porcine skeletal muscle, also known calcium (Ca$^{2+}$) release channel, has been associated with swine PSS and halothane sensitivity. We used the PCR-RFLP(restriction fragment length polymorphism) and PCR-SSCP (single strand conformation polymorphism) methods to detect the PSS gene mutation (C1843T) in the RYR1 gene and to estimate genotype frequencies of PSS gene in Korean pig breed populations. In PCR-RFLP and SSCP analyses, three genotypes of homozygous normal (N/M), heterozygous carrier (N/n) and homozygous recessive mutant (n/n) were detected using agarose or polyacrylamide gel electrophoresis, respectively. The proportions of normal, carrier and PSS pigs were 57.1, 35.7 and 7.1％ for Landrace, 82.5, 15.8 and 1.7％ far L. Yorkshire, 95.2, 4.8 and 0.0％ for Duroc and 72.0, 22.7 and 5.3％ for Crossbreed. Consequently, DNA-based diagnosis for the identification of stress-susceptible pigs of PSS and pigs producing PSE meat is a powerful technique. Especially, PCR-SSCP method may be useful as a rapid, sensitive and inexpensive test for the large-scale screening of PSS genotypes and pigs with PSE meat in the pork industry.y.