• Korean Journal of Veterinary Research
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• v.45 no.2
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• pp.297-302
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• 2005

The present experiment was performed in order to know the anti-emetic effect of acupuncture, aquapuncture with metoclopramide and moxibustion on the xylazine induced emesis in dogs. The animals were devided into a control group (non-acupoint) and two experimental groups (BL-20 and LIV-13), respectively. Acupuncture, aquapuncture with metoclopramide (1 mg/kg) and moxibustion were applied to animals for 20 minutes before xylazine injection (2.2 mg/kg, IM). In acupuncture group, the emetic rates in BL-20 (16.7%) and LIV-13 (16.7%) were lower than that of control group (50%), respectively. In aquapuncture group, the emetic rates in BL-20 (16.7%) and LIV-13 (0.0%) were lower than that of control group (50%), respectively. In moxibustion group, the emetic rates in BL-20 (50%) and LIV-13 (16.7%) were lower than that of control group (83.3%), respectively. Considering above the findings collectively, it is considered that acupuncture, aquapuncture with metoclopramide and moxibustion at BL-20 and LIV-13 are effective and especially aquapuncture with metoclopramide at LIV-13 is the most effective treatment to prevent the emesis induced by xylazine among groups.

• Korean Journal of Veterinary Research
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• v.45 no.3
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• pp.399-403
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• 2005

This study was performed to elucidate the effect of acupuncture and aqua-acupuncture in dogs. Each group was divided into control (18 dogs), PC-6 (6 dogs) and BL-21 (6 dogs) group for the antiemetic effect of acupuncture, respectively. And, the animals were divided into control (18 dogs), PC-6 (18 dogs) and BL-21 (18 dogs) group for the antiemetic effect of aqua-acupuncture with metoclopramide, respectively. 2% xylazine was injected to the all dogs to induce the emesis, and acupuncture and aqua-acupuncture treatment (0.5% metoclopramide) were applied to animals for 20 min. before xylazine injection, respectively. Emetic rates in PC-6 (33.3%) and BL-21 (16.7%) were lower than that of control group (44.4%) in acupuncture groups, respectively. Emetic rates in PC-6 (16.7%) and BL-21 (0.0%) were lower than that of control group (38.9%) in aqua-acupuncture groups, respectively. Based on these findings, it was considered that the antiemetic effects of acupuncture and aqua-puncture at BL-21 were more effective than those of PC-6 groups, and aqua-acupuncture with metoclopramide at BL-21 was the most effective among them.

• Korean Journal of Acupuncture
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• v.23 no.1
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• pp.111-118
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• 2006

Objectives : To test the therapeutic efficacy of acupuncture applied to PC6 and ST36 for the relief of fullness of epigastrium or epigastric pain. Subjects and Methods : We enrolled fifty patients in a case series study The patients were mainly female (94 %) with an average age of 55 years $({\pm}15.0)$; the average age of the male patients was 51 years $({\pm}20.0)$. Twenty four percent of patients were in acute phase which epigastric pain had lasted below 1 month. Twenty eight percent of patients were in chronic phase which the pain had lasted over 6 month. The rest were in subacute phase. Acupuncture needles were inserted into PC6 and ST36 bilaterally. The acupuncture treatments were performed 2 times a week for 4 weeks. One treat session was lasted for 30 min. At each visit, overall symptomatic improvement, frequency and intensity of symptoms were checked on a 4 scaled questionnaire. Results : After acupuncture treatment, a progressive improvement of pain intensity was reported in 46 of the 50 patients, including 23 of excellent and 23 of good. The progress of symptom was more superior in subacute phase to acute or chronic phase. The symptom of 22 of 24 patients in subacute phase was improved. No patient experienced minor side-effects during acupuncture treatment. Conclusion : These preliminary data suggest the acupuncture treatment provides good pain relief for most patients presenting with epigastric pain. Randomized trials with appropriate control groups are needed to validate the effectiveness of this therapy in the treatment of epigastric pain.

• Korean Journal of Acupuncture
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• v.20 no.4
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• pp.31-40
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• 2003

Objectives : The purpose of this study is to investigate whether Haenggan(LR2) Reduction in Acupuncture affects cerebral hemodynamics〔regional cerebral blood flow(rCBF), mean arterial blood pressure(MABP)〕in normal rats, and to make manifest whether Haenggan(LR2) Reduction in Acupuncture is mediated by cyclooxygenase or guanylate cyclase. Methods : This experiments was to investigate at the other changes of rCBF and MABP at Haenggan(LR2) Reduction in Acupuncture in normal rats, pretreated rats with indomethacin(1 mg/kg, i.v.) and pretreated rats with methylene blue$(10\;{\,u}g/kg,\;i.v.)$. Results : 1. Haenggan(LR2) Reduction in Acupuncture was significantly increased rCBF during acupuncture and after withdrawing of the needle. 2. Haenggan(LR2) Reduction in Acupuncture was decreased MABP during acupuncture, but Haenggan(LR2) Reduction in Acupuncture was increased MABP in compared with normal condition. 3. Pretreatment with indomethacin(1 mg/kg, i.v.) was significantly inhibited Haenggan(LR2) Reduction in Acupuncture induced increase of rCBF, but was increased Haenggan(LR2) Reduction in Acupuncture induced increase of MABP. 4. Pretreatment with methylene blue$(10\;{\mu}g/kg,\;i.v.)$ was significantly decreased Haenggan(LR2) Reduction in Acupuncture induced increase of rCBF and MABP. This results suggest that Haenggan(LR2) Reduction in Acupuncture increased rCBF by dilating pial arterial diameter, and the mechanism of Haenggan(LR2) Reduction in Acupuncture is mediated by guanylate cyclase.

• Korean Journal of Acupuncture
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• v.20 no.4
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• pp.1-16
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• 2003

Objectives : This study was examined for effects of acupuncture of Hyeong points' Acupuncture of Three Foot-eum Collaterals on the abdominal thermography of health subject. Methods : The volunteers who participating in this study had taken rest for 20 - 30 minutes in room temperature $(23-25^{\circ}C)$ before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day. The thermography of abdomen including a below part of the chest was taken using Infra-Red Imaging System (IR 2000, MEDI-CORE Co., Korea) by time interval of 15 minutes at 15 minutes before, just before and 15 minutes after, 30 minutes after and 45 minutes after acupuncture stimulation. Acupuncture was applied to the left Hyeong points' Acupuncture of Three Foot-eum Collaterals for 30 minutes. Results : The results showed that acupuncture of Hyeong points had more potencies of changes on all the ROIs of abdominal thermography than those of control group. Also, it was observed that the quantities of thermal changes following acupuncture of Hyeong points been increased comparing that of control group at all the ROIs (region of interest). Observed the thermography classified by ROI, however, it was failed that acupuncture of Hyeong points could modulate the specific areas concerning to the abdominal pathway of Three Foot-eum Collaterals. Conclusions : These results suggest that acupuncture of Hyeong points may modulate thermal distributions and changes of abdominal areas including the below of chest.

• Korean Journal of Acupuncture
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• v.24 no.1
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• pp.95-111
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• 2007

Objectives : This research ws performed to investigate the effect of manual acupuncture at TE4, SP3 and TE4+SP3 on body weight, blood glucose, BUN, creatinine, lipid metabolism, liver function and morphological change of hepatic tissue in hyperglycemia rats. Methods : Experimenal groups were divided into hyperglycemia group(Control group), hyperglycemia and acupuncture therapy group at SP3, hyperglycemia and acupuncture therapy group at TE4, hyperglycemia and acupuncture therapy group at TE4+SP3 , once per 2 days during 5 weeks. Results : Body weight was decreased significantly in TE4 group of fifth week compared with Control group. Blood glucose was decreased significantly in SP3 group compared with control group. Creatinine was decreased significantly in TE4 and TE4+SP3 group compared with control group. Total cholesterol was decreased significantly in TE4+SP3 group compared with control group. Triglyceride was decreased significantly in TE4 gorup compared with control group. In the morphological change of hepatic cell, TE4 and SP3 group were showed he rough endoplasmic reticulum forms aggregates of parallel, flattened cisternae scattered randomly throughout the cytoplasm compared with control gruop. Conclusions : Acupuncture at TE4 can manage hyperglycemia by controlling body weight, and lipid metabolism in hyperglycemia rats induced by streptozotocin.

• The Journal of Korean Medicine
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• v.19 no.2
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• pp.271-295
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• 1998

This study was performed from October 1997 to March 1998 on 42 healthy students to observe the effects of acupuncture at Hap-kok (LI4) according to the meridian and qi-xue(氣血) phenomenon of oriental medicine's theory. Skin temperature on the Kok-Chi(LI11) and Yong-Hyang(LI20) were measured by D. I. T. I. (Digital Infrared Thermograph Imaging) before acupuncture stimulation, 1min after and after acupuncture stimulation during 10 min. 1. In healthful man, average skin temperature about Kok-Chi area was in low than Yong-Hyang, and temperature change for 10 min was decreased significantly. 2. In Kok-Chi, the temperature decrease index of execution was shown in low than control. 3. When the temperature of Yong-Hyang(left) was higher, the index was shown in high than control. 4. When the temperature of Kok-Chi (left) was higher, execution temperature change was decreased significantly than control. The above results indicates that D. I. T. I. was a useful method to observe follow-up the effects and changes by acupuncture stimulation on objective evaluation of phenomenon for the meridian system. Thus, acupuncture on LI4 affects to thermal changes of ST25 and LI4, but exact examination of thermal changes on ST25 will have to be.

• Journal of Acupuncture Research
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• v.18 no.6
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• pp.105-113
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• 2001

Objective : This study was performed to evaluate the effect of acupuncture on cerebral blood flow by Transcranial Doppler Ultrasonography(TCD) Method : Monitoring of TCD was examined in 11 healthy women volunteer(mean $age:\;24.5{\pm}2.9\;\;years$) before, during and after acupuncture on Paekoe(GV20). Mean velocity, pulsatility index, systolic velocity and diastolic velocity values are analyzed from DWL. MDX4 at different depths of both middle cerebral artery. Results : The results showed a significant(p<0.05; Friedman test & Wilcoxon signed ranks test) increase in mean velocity, systolic velocity and diastolic velocity decrease in pulsatility index, which was measured at different depths of both middle cerebral artery. Conclusion : These results suggest that acupuncture could have a specific effect on cerebral blood flow.

• Journal of Acupuncture Research
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• v.32 no.2
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• pp.169-185
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• 2015

Objectives : The purpose of this study is to find the effects of Sa-am liver tonifying and sedating acupuncture on radial pulse. Methods : Sixty healthy people were divided into a liver tonifying acupuncture(LTA) group, liver sedating acupuncture(LSA) group, and control group. The LTA group and LSA group received acupuncture for 20 minutes with a supine position. The Control group took a rest without receiving acupuncture. Radial pulse was measured by three dimensional pulse imaging system(DMP-3000) at four different time points (before, right after, 30 minutes after, and 60 minutes after acupuncture). We compared the three groups and figure out determined the parameters which significantly changed after acupuncture treatment. Results : 1. Pulse period, T1/T, T4/T, (T-T4)/T, T4/(T-T4), T5/T significantly changed after acupuncture. 2. H4, pulse area, systolic pulse area, diastolic pulse area, radial augmentation index(RAI), and pulse power volume / min significantly changed after acupuncture. 3. Frequency of Fourier components, ratio of frequencies of Fourier components, magnitude of Fourier components, and ratio of magnitudes of Fourier components significantly changed after acupuncture. Conclusions : LTA and LSA have an effect on the radial pulse parameters. Further studies on radial pulse change using Sa-Am acupuncture are needed.

• Journal of Acupuncture Research
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• v.32 no.2
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• pp.105-121
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• 2015

Objectives : The purpose of this study is to observe the effects of Sa-am acupuncture with tonifications of kidney and urinary bladder on radial pulse in healthy subjects. Methods : Sixty healthy subjects participated in this study, and were divided into a kidney tonifying acupuncture group(KI group), urinary bladder tonifying acupuncture group(BL group) and control group. Radial pulse was measured by 3 dimensional pulse imaging system(DMP-3000) before, immediately after, 30 minutes after, and 60 minutes after acupuncture at Cun, Guan, and Chi in each time. Results : 1. BL group exhibited significantly reduced T1 / T, T4 / T, T4 / (T-T4), T5 / T and increased(T-T4) / T compared to KI group. 2. BL group showed increase of radial augmentation index / heart rate(RAI / HR) in left Cun, H5, Ad / Ap in left Chi, H1, As / Ap in right Chi compared to KI group. BL group showed decrease of As / Ap, Aw / Ap in left Chi, H1, pulse depth, Ad / Ap in right Chi compared to KI group. 3. KI group showed increase of Aw / Ap, H1, H2, H4, pulse area in right Guan, pulse depth in right Chi compared to BL group. KI group showed decrease of RAI in left Cun, applied pressure, pulse depth in left Guan, Aw / Ap in right Chi compared to BL group. Conclusions : The effects of Sa-am acupuncture with tonifications of kidney and urinary bladder in healthy humans have been observed on various parameters. The parameters analysed in this study can be used to differentiate the effects of Sa-am acupuncture with tonifications of kidney and urinary bladder on radial pulse.