• Science of Emotion and Sensibility
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• v.5 no.4
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• pp.51-57
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• 2002

The purpose of the study was to measure and compare driver's psychophysiological responses in different driving conditions through driving simulator. Twelve male adults(more than 1 year of driving experience) were assigned to four different driving conditions, such as normal speed(70㎞/h), sudden start(0㎞/h→70㎞/h), and sudden stop(70㎞/h→0㎞/h), and their simulator sickness, subjective pleasantness and arousal, EEG, ECG, skin temperature, and GSR were measured. Subjective and physiological evaluations were executed before and after driving in each condition. The results showed that subjective pleasantness and arousal increased in sudden stop and sudden start conditions, relative to stop and normal speed conditions. As the central nervous responses, beta wave increased and alpha wave decreased in sudden stop and sudden start conditions, relative to stop and normal speed conditions. With regard to the autonomic responses, heart rate and GSR increased, while skin temperature decreased in sudden stop and sudden start conditions, which means an activation of sympathetic nervous system. The results suggested that based upon observation of the distinctive psychophysiological changes by driving conditions, it is possible to evaluate the human sensibility in dynamic environment.

• Journal of the Korean Institute of Intelligent Systems
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• v.13 no.2
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• pp.186-191
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• 2003

Skills in tracing of the MR divide into following, approaching, avoiding and warning and so on. It is difficult to have all these skills learned as neural network. To make this up for, skills consisted of each module, and Mobile Robot was controlled by the output of module adequate for the situation. A mobile Robot was equipped multi-ultrasonic sensor and a USB Camera, which can be in place of human sense, and the measured environment information data is learned through Modular Neural Network. MNN consisted of optimal combination of activation function in the Expert Network and its structure seemed to improve learning time and errors. The Gating Network(GN) used to control output values of the MNN by switching for angle and speed of the robot. In the paper, EN of Modular Neural network was designed optimal combination. Traveling with a real MR was performed repeatedly to verity the usefulness of the MNN which was proposed in this paper. The robot was properly controlled and driven by the result value and the experimental is rewarded with good fruits.

• The Korean Journal of Pharmacology
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• v.24 no.1
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• pp.83-92
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• 1988

Although the release of lysosomal enzymes from activated PMN leukocyte can be regulated by intracellular cyclic nucleotide levels, other responses of PMN leukocyte according to the binding of neurotransmitters to either ${\beta}$-adrenergic or muscarinic receptors are still not clarified. In addition, the function of PMN leukocyte mediated by ${\alpha}$-adrenergic receptors is uncertain. Atropine, phentolamine and propranolol inhibited calcium uptake, superoxide generation, NADPH oxidase activity and phagocytic activity in activated PMN leukocyte, whereas carbachol and isoproterenol slightly further stimulated the responses of activated cells. Either carbachol or isoproterenol stimulated superoxide generation was inhibited by their antagonists, atropine and propranolol, respectively. The response of activated PMN leukocyte was inhibited by chlorpromazine, verapamil and dantrolene but slightly stimulated by lithium. On the other hand, chlorpromazine and dibucaine did not affect NADPH oxidase activity. Atropine, phentolamine and propranolol suppressed the calcium dependent phagocytic activity. Thus, the results suggest that atropine, phentolamine and propranolol may inhibit superoxide generation in activated PMN leukocyte by the inhibition of calcium influx and by their direct action on the NADPH oxidase system which is associated with autonomic receptors.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2004.11a
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• pp.203-208
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• 2004

We are living now under the bad air pollition contained the many plus(+)ion produed by the exhaust gases from automobil and Industrial plant. To be refreshe those air pollution. We developed the funtional lighting fixture which emit the lighting, negative(-)ion and Infraredray. The negative(-)ion and Infraredray refresh the air pollition and will arise nature healing power lot the human body and activate the body cell, and makes the good blood circulation and then we had the experiment to the Biological effect by the funtional lighting fixture.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2007.10a
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• pp.170-174
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• 2007

Although research efforts for brain waves have prospered in medicine and engineering, acupuncture still has a long way to go regarding researches on brain waves analysis. Thus this study set out to analyze brain waves stimulated by indirect mugwort moxibustion, which was part of acupuncture techniques, and to investigate their correlations with the automatic nervous system. For the experiments, stimulation was given to Jungwan, Shingwol and Gwanwon, which were some of the spots on the body suitable for acupuncture, through indirect mugwort moxibustion. The subjects' brain waves were measured before the stimulation, during the stimulation, and one hour and two hours after the stimulation. The measurements were analyzed with Matlab 7.0 for FFT and frequency power spectrum. Then the ${\alpha}$, ${\beta}$, ${\delta}$, and ${\theta}$ waves were analyzed and examined for changes to the percentage of each frequency and to the amplitude of vibration according to the stages of stimulation. The EEG data of the entire brain were translated into FFT to analyze the percentage of the ${\alpha}$, ${\beta}$, ${\delta}$, and ${\theta}$ waves. As a result, the ${\alpha}$ waves recorded a double increase after the stimulation. The power spectrum analysis results of the entire brain decreased the ${\alpha}$ and ${\beta}$ waves dropping in the energy level, which suggested that the parasympathetic nerves were activated. When the results of the study were compared with those of the previous study, it's confirmed that indirect moxibustion stimulation could cause changes to the automatic nervous system and bring stability to those who were nervous or under stress due to the proportionate increase of the ${\alpha}$ waves.

• Clinical and Experimental Pediatrics
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• v.46 no.7
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• pp.695-701
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• 2003

Purpose : It had been suggested that pain arising from deep somatic body regions influences neural activity within periaqueductal gray(PAG) of midbrain via distinct spinal pathways. Aspirin is one of the popular non-steroidal anti-inflammatory drugs used in the management of pain. Fos expression was used as a marker for neuronal activity throughout central neurons following painful peripheral stimulation. This study was prepared to investigate changes of c-Fos immunoreactivity in midbrain by deep pain and effects of aspirin. Methods : Male Sprague-Dawley rats were injected with 0.1 mL of 5% formalin in the plantar muscle of the right hindpaw. For experimental group II, aspirin was injected intravenously before injection of formalin. An aspirin-untreated group was utilized as group I. Rats were sacrificed at 0.5, 1, 2, 6 and 24 hours after formalin injection. Rat's brains were removed and sliced in rat brain matrix. Brain slices were coronally sectioned at interaural 1.00-1.36 mm. Serial sections were immunohistochemically reacted with polyclonal c-Fos antibody. The numbers of c-Fos protein immunoreactive neurons in ventrolateral periaqueductal gray(VLPAG) and dorsomedial periaqueductal gray(DMPAG) were counted and analyzed statistically with Mann-Whitney U tests. Results : Higher numbers of c-Fos protein immunoreactive neurons were found in VLPAG. In both VLPAG and DMPAG of formalin-treated group, the numbers of c-Fos protein immunoreactive neurons were significantly higher at all time points than the formalin-untreated group, which peaked at two hours. The numbers of c-Fos immunoreactive neuron of the aspirin-treated group were less compared to the aspirin-untreated group at each time point. Conclusion : These results provide some basic knowledge in understanding the mechanism of formalin-induced deep somatic pain and the effects of aspirin.