• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 1997.11a
• /
• pp.80-84
• /
• 1997

본 연구는 뇌파의 주파수 변화특성이 다양한 시각자극에 의해서 유발된 감성을 평가할 수 있는가를 알아보고자 하였다. 특히 쾌감성과 불쾌감성의 차이, 쾌감성내의 차이를 뇌파를 이용하여 객관적으로 변별할 수 있는 가를 알아보았다. 사용된 시각자극은 8개의 긍정자극과 7개의 부정자극이었다. 각각의 자극은 30초씩 무선적으로 제시되었고, 각자극의 제시사이마다 120초씩의 휴식기를 두었다. 매 자극제시 후 피험자는 제시된 자극에 대해 긍정.부정의 정도를 주관적으로 평가하였다. 실럼참가자는 20명의 대학생이었으며, 뇌파는 뇌의 21부위에서 기록되었다. 기록된 뇌파에 대해 FFT(Fast Fourier Transformation)분석을 실시한 후, normalized sensitivity를 구현하였다. 자극 중 최대긍정(the most positive stimulus), 최대부정(the most negative stimulus), 최소긍정(the least positive stimulus), 최소부정(the least negative stimulus)이라고 주관적으로 평가한 자극을 보고 있을때의 뇌파를 측정하여 비교.분석하였다. 그 결과 뇌파의 주파수 변화는 극단의 긍정감성과 부정감성의 차이를 변별할수 있고, 긍정감성내의 차이와 부전감성내의 차이를 변별할 수 있었다. 또한 부정감성을 느낄때보다는 긍정감성을 느낄수록 alpha파의 출현량은 증가하고, delta파와 beta파의 출현량은 감소하고 있음을 보여주었다. 결론적으로, 뇌파의 주파수 변화는 다양한 시각자극에 의해 유발된 감성을 측정할 수 있음을 암시한다.

• The Korean Journal of Physiology
• /
• v.23 no.1
• /
• pp.129-138
• /
• 1989

In an attempt to characterize the ventral root afferent fibers, arterial blood pressure responses to stimulation of the ventral root (VR) were observed in anesthetized cats. Effects of the morphine administered either intravenously or direct spinally and of the spinal lesions on the pressor responses were compared. Followings are the results obtained. 1) Stimulation of the VR with C-strength, high frequency stimuli evoked a marked pressor response. No depressor response, which had been reported during peripheral nerve stimulation, was observed during VR stimulation with low frequency. 2) Acute cervical spinalization abolished the pressor response, indicating the involvement of supraspinal mechanism. 3) The ascending spinal pathways of the pressor response were located in the dorsolateral funiculus bilaterally. 4) Intravenously administered morphine exaggerated the pressor response to VR stimulation, while direct spinally administered morphine suppressed it. From the above results it was concluded that the ventral root afferent fibers have more similar properties to muscular C-afferent fibers than to cutaneous C-fibers.

• Journal of the Korea Convergence Society
• /
• v.12 no.6
• /
• pp.27-32
• /
• 2021

The purpose of this study was to compare the immediate effect of EMS (electrical muscle stimulation) on rectus femoris thickness during resisted knee extension exercise in healthy adults. This experiment was conducted on 20 healthy adults as pretest-posttest nonequivalent one group design. The subject's 1RM of both knee extension was measured indirectly using an elastic band, and the knee extension resistance exercise using an elastic band was applied to high intensity (80% of 1RM) on the right leg and low intensity (50% of 1RM with EMS) on the left leg, which were applied with 5 sets. Muscle measurements were performed on the rectus femoris (1/2 site, 1/4 site) using ultrasonography before and after exercise. There was a statistically significant difference on the thickness of the rectus femoris in low intensity exercise of the elastic band applied with EMS between pre-test and post-test (p<.05). The results of this study showed that elastic band low intensity exercise combined with EMS had an immediate effective in increasing the thickness of rectus femoris. Based on this result, it is also necessary to verify the effectiveness of intervention methods incorporating low-intensity resistance exercises applying EMS to elderly who cannot exercise high-intensity resistance training in the future, and to develop exercise programs for various body parts.

• Journal of Food Hygiene and Safety
• /
• v.36 no.1
• /
• pp.17-23
• /
• 2021

This evaluation tested the skin irritation and sensitization of an acaricide (Wagoojabi II®, WGJB) for the control of poultry red mite, containing 20% Chamaecyparis obtusa oil and 56% Cinnamomum camphora oil. In a primary skin irritation test, rabbits were dermally treated with WGJB for 24 h. The acaricide did not induce any adverse reactions such as erythema and edema on intact skin sites, but on abraded skin sites, some rabbits showed very slight erythema and edema 24 h after topical application. So, the acaricide was classified as a practically mild-irritating material based on a 0.625 primary irritation index score. In the skin sensitization test, guinea pigs were sensitized with intradermal injection of 0.1mL WGJB for 24 h. After 1 week, The WGJB was treated on the site of injection, and challenged 2 weeks later. The WGJB did not induce any allergic reactions. Therefore, the WGJB was graded as a weak material at '0' in both sensitization score and rate. From the results of this study, it is suggested that WGJB does not cause contact irritation and sensitization.

• Investigative Magnetic Resonance Imaging
• /
• v.3 no.1
• /
• pp.47-52
• /
• 1999

Purpose : The purpose of this study was aimed to evaluate the BOLD(blood oxygen level dependent) contrast fMRI(functional MR imaging) in the occipital lobe and to compare with the metabolic changes based on H MRS (MR spectroscopy) and MRSI (MR spectroscopic imaging) before and after visual stimulation Materials and Methods : Healthy human volunteers (eight males and two females with 24-30 year age) participated in this study. All of the BOLD fMRI were acquired on a 1.5T MR with EPI during supervised visual stimulation in the occipital lobe. The red flicker with 8Hz was used for visual stimulation. After imaging acquisition, the MR images were transferred into unix workstation and processed with acquired from the same location based on the activation map. MRSI (magnetic resonance spectroscopic imaging) was also acquired to analyze the lactate changes before and after stimulation. Results : The activation maps were successfully produced by BOLD effect due to visual stimulation. NAA (N-acetyle aspartate)/Cr (creatine) ratio varied only from $1.79{\pm}0.28{\;}to{\;}1.88{\pm}0.20$ in activation area before and after stimulation. However, the signal intensity of lactate was elevated $9.48{\pm}4.38$ times higher than before activation. Lactate metabolite images were consistent with the activation maps. Conclusion : The BOLD contrast fMRI is enough sensitive to detect the activated area in human brain during the visual stimulation. Lactate metabolite map presents the evidence of lactate elevation on the same area of activation.

• Journal of the Korean Magnetics Society
• /
• v.21 no.5
• /
• pp.180-184
• /
• 2011

The changes in the blood flow in the peripheral vascular system under strong pulsed magnetic fields (pMF) were studied by digital infrared thermal imaging (DITI). After pMF stimulus temperatures in stimulated area were commonly increased in both groups of age and gender. In order to reduce heat generated from coil in pMF stimulus system plastic moldings were fabricated, so that certain distance was kept between stimulus system and the skin and to prevent direct contact to the skin. It is believed that skin temperature is increased by internal electromagnetic energy stimulated the peripheral vascular system by non-contact method.

• Journal of Korean Medicine Rehabilitation
• /
• v.18 no.4
• /
• pp.39-61
• /
• 2008

Objectives : The present study was performed to investigate whether acupuncture stimulation in the rats affected regeneration properties of the injured sciatic nerve. A differential effect of acupuncture stimulation on the one point near the spinal nerve root controlling sciatic nerve activity and the other point in the peripheral area subordinated by injured nerve was compared. Materials and Methods: Rat sciatic nerves were injured by crush, and the effects on axonal regeneration on injured sciatic nerves were evaluated by acupuncture stimulation at two different regions. In proximal acupuncture stimulation group, acupuncture stimulation was performed on Huatuo Jiaji(EX B2) points located from L5 to S1 vertebral levels to stimulate the nearest spinal nerve root that innervates sciatic nerves. In distal acupuncture stimulation group, acupuncture stimulation was performed on Zusanli(ST 36) and Weizhong(BL 40) points to stimulate at peripheral area dominated by injured sciatic nerves. Acupuncture stimulation was given every other days for 1 or 2 weeks. Sciatic nerve tissues collected from acupuncture stimulation experimental groups, injury control group, and intact animal group were used for protein analysis by Western blotting or Hoechst nuclear staining. To determine axonal regeneration, Dil fluorescence dye was injected into the sciatic nerve 0.5 cm distal to the injury site in individual animal groups and Dil-labeled cells by retrograde tracing were measured in the DRG at lumbar 5 or in the spinal cord. DRG sensory neurons prepared from individual animal groups were used to measure the extent of neurite outgrowth and for immunofluorescence staining with anti-GAP-43 antibody. Results : Animal groups given proximal or distal acupuncture stimulation showed upregulation of GAP-43 and Cdc2 protein levels in the sciatic nerve at 7 days after injury. Cdk2 protein levels were strongly induced by nerve injury, but did not show changes by acupuncture stimulation. Phospho-Erk1/2 protein levels were elevated by acupuncture stimulation above those present in the injury control animals. These increase in regeneration-associated protein levels appeared to be related with increase cell proliferation in the injured sciatic nerves. Hoechst 33258 staining of sciatic nerve tissue to visualize nuclei of individual cells showed increased Schwann cell number in the distal portion of the injured nerve 7 and 14 days after injury and further increases by acupuncture stimulation particularly at the proximal position. Measurement of axonal regeneration by retrograde tracing showed significantly increased Dil-labeled cells in proximal acupuncture stimulation group compared to distal acupuncture stimulation group and injury control group. Finally, an evaluation of axonal regeneration by retrograde tracing showed increased number of Dil labeled cells in the DRG at lumbar 5 or in the ventral horn of the spinal cord at lower thoracic level at 7 days after nerve injury. Conclusions : The present data show that the proximal acupuncture stimulation at Huatuo Jiaji(EX B2) points governing injured sciatic nerves was more effective for axonal regeneration than the distal acupuncture stimulation. Further studies on functional recovery or associated molecular mechanisms should be critical for developing animal models and clinical applications.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.35 no.11
• /
• pp.1213-1217
• /
• 2011

Electric stimulators are used for various treatments, such as for pain relief and to improve rehabilitation in and out of the hospital. However, if the stimulation pulse affects the patient's heart, it can cause critical cardiac disorders such as arrhythmia or ventricular fibrillation. As a result, it must be ensured that the transmission length of the stimulation pulse does not exceed the proper range in the design of an electric stimulator. Furthermore, every anticipated risk factor must be monitored in in-vitro and in-vivo experiments. A new stimulator was designed to supply continuous 0.001 J stimulation pulses at a rate of 60 pulses per second. To evaluate the safety of the new electric stimulator and to measure its energy transfer and pulse transmission length, we built a conduction model that was filled with saline and measured the electric field at various positions in response to real stimulations. In an animal experiment with two pigs, heart disorders were induced by applying electric stimulation to tissues near the heart. These heart disorders were different from the result obtained with 9 V DC stimulation.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 2009.05a
• /
• pp.163-166
• /
• 2009

본 연구는 동영상자극에 의한 정서유발시의 표정변화와 생리반응을 밝혀내는 것을 목적으로 실행되었다. 18명의 실험참가자에게 각각 2종류씩의positive, negative 그리고neutral의 총5가지의 동영상자극을 약5분간 제시하였다. 표정변화는 비디오카메라로 기록하였고, 생리반응으로 뇌파(64ch), 심전도, 임피던스카디오그램, 안면근전위등을 측정했다. 표정의 분석결과, positive조건은 neutral조건에 비해 눈구석간의 거리가 감소하였고, 입 꼬리간의 거리는 증가하였다. 반면, negative조건은 neutral조건에 비해 오른쪽 눈구석과 눈 꼬리간의 거리가 증가하였다. 뇌파의 alpha/beta ratio변화량에 있어 positive조건은 neutral조건에 비해 우전두엽을 중심으로 감소하였고, negative조건은 좌전두엽에서 감소하였다. 심박수 및 PEP/LVET는 negative조건에서만 감소하였다. 또한, 근전위의 변화는 positive조건이 neutral조건보다 좌우볼 및 입부위에서 증가한 반면, negative조건은 좌우눈썹부위에서 증가하였다. 이에 본 연구를 통해, 정서유발시의 표정변화와 생리반응의 특성을 알 수 있었다.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.8 no.12
• /
• pp.1949-1958
• /
• 2013

This study conducted observation of tissues using the immunohistochemistry methods in order to see the effect of Needle Electrode Electrical Stimulation(: NEES) on apoptosis in the SD rat cerebellum caused by global ischemia which came from common carotid artery occlusion. The comparison and analysis results of expression of factors related to apoptosis among the control group, the global ischemia group and the NEES group showed that NEES following global ischemia had a significant effect on the reduction of c-fos expression in the SD rat cerebellum, and didn't have a significant effect on the reduction of bax and caspase-3 expression. In conclusion, it is considered that NEES following global ischemia is partially effective in suppressing the expression of factors related to apoptosis.