• Journal of Sensor Science and Technology
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• v.10 no.1
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• pp.1-8
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• 2001

Conventional microgyroscopes of vibrating type require resonant frequency tuning of the driving and sensing modes to achieve high sensitivity. These tuning conditions depend on each fabricated microgyroscopes, even though the microgyroscopes are identically designed. A new micromachined resonator, which is applicable to microgyroscopes with self-toning characteristics, is presented. Since the laterally driven two degrees of freedom (2DOF) resonator was designed as a symmetric structure with identical stiffness in two orthogonal axes, the resonator is applicable to vibrating microgyroscopes, which do not need mode tuning. A dynamic model of the resonator was derived considering gyroscopic application. The dynamic model was evaluated by experimental comparison with fabricated resonators. The microgyroscopes were fabricated using a simple 2-mask-process of a single polysilicon layer deposited on an insulator layer. The feasibility of the resonator as a vibrating microgyroscopes with self-tuning capability is discussed. The fabricated resonators of a particular design have process-induced non-uniformities that cause different resonant frequencies. For several resonators, the standard deviations of the driving and sensing frequencies were as high as 1232Hz and 1214Hz, whereas the experimental average detuning frequency was 91.75Hz. The minimum detuned frequency was 68Hz with $0.034mVsec/^{\circ}$ sensitivity. The sensitivity of the microgyroscopes was low due to process-induced non-uniformity; the angular rate bandwidth, however, was wide. This resonator could be successfully applicable to a vibrating microgyroscopes with high sensitivity, if improvements in uniformity of the fabrication process are achieved. Further developments in improved integrated circuits are expected to lower the noise level even more.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2003.05a
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• pp.233-234
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• 2003

근교약세의 요인으로는 열성유해유전자의 호모 접합체화에 의한 적응성의 저하가 생각되어진다. 그 중에서도 가장 유해성이 높은 유전자로는 열성치사유전자가 있다. 그러나, 이러한 열성 치사유전자을 보유한 개체는 죽어버리기 때문에 직접적인 검출은 불가능하다. 따라서, 동조염색체의 호모화가 되는 교배실험과 표식유전자에 의한 연사분석이 필요하다. 본 연구는 참전복의 열성치사유전자의 유무을 명확히 파악하기 위하여 형매교배와 비형매교배을 포함한 전체교배를 하였으며, 참전복을 대상으로 개발한 마이크로사데라이트(microsatellite)좌을 유전표식으로 이용하여 각 교배구의 유전자형의 분리를 조사했다. (중략)

• Journal of the Korean Society for Precision Engineering
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• v.17 no.11
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• pp.81-87
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• 2000

A new resonator that is fabricated by single polysilicon layer process is presented. The resonator can move in two orthogonal direction on the plane parallel to the substrate. And the resonant frequencies of the two modes are intrinsically designed to be identical since the overall structure of the resonator is symmetric about the two directions of motion. Since the resonator ideally has two identical vibration mode, it can be applied to various micro-devices that requires multi DOF motion, especially to microgyroscopes. To investigate the feasibility of application of the resonator, dynamic model of the resonator including the nonlinear behavior of driving electrodes is derived and evaluated with the fabricated one, and the self-tuning characteristics are proved though experiments.

• Proceedings of the KIEE Conference
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• 1999.07b
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• pp.894-896
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• 1999

PID 제어는 50년의 역사를 갖기 때문에 현장의 사용자는 이 제어방식에 익숙해져 있으며, 제어장치의 구성이 간단하며 제어기의 최적동조가 가능하므로 많은 분야에서 사용되고 있다[1]. 그러나 PID 제어기에 의해서 얻은 결과에 대하여 만족하기 위해서는 많은 시행착오를 겪어야 한다. 또한 만족하는 결과를 얻었다고 할지라도 외란, 플랜트의 동특성이 바뀌는 경우 시스템을 추종하지 못하기 때문에 파라미터를 재조정하여야 한다. 유전 알고리즘은 자연세계의 진화 현상에 기초한 계산모델로서 John Holland에 의해서 1975년에 개발된 전역적인 최적화 알고리즘이며[1][2], 비선형 고차원, 불연속, 다중모드, 노이즈 함수 등에 대하여 강건함을 보여주고, 복잡한 탐색 공간에서 최적 값을 스스로 발견하는 학습 능력을 갖는다. 이 방법은 재생산, 교배, 돌연변이를 통하여 최적해를 찾은 방법으로 1989년에 D. E. Goldgerg에 의해서 체계적으로 정리된 후 여러 분야에서 응용되고 있다[3][4]. 그러나 유전 알고리즘은 목적함수만을 이용하여 해집단을 탐색하기 때문에 숙련운전자가 원하는 제어 특성 명세인 상승시간, 정착시간, 초과량(oveshoot) 둥을 구체적으로 명시하여 제어에 반영할 수 없다. 또한, 유전 알고리즘은 입력 값이 크게 바뀔 경우 다른 시스템으로 인식하여 새로운 탐색을 수행하는 단점을 가지고 있다. 본 논문은 첫째, 기준모델을 도입하여 플랜트의 성능을 기준모델로 표현하여 플랜트가 요구하는 성능지표를 정량적으로 규정하는 것이 가능하였다. 또한, 이것은 미지 플랜트 동특성을 식별하기 위한 신호로 사용되어, 플랜트의 정보를 얻는데 이용되었다. 즉, 기준모델과 플랜트 출력사이의 추종 오차 정보가 적응기구인 PID 유전제어기의 입력으로 사용되며, 구형파 입력의 경우에도 기준모델과 플랜트의 출력차는 크게 변하지 않는다. 따라서, 유전 알고리즘의 목적함수에 기준 모델을 제안 적용하여 안정적이고, 세밀한 제어를 수행하였다. 둘째, PID의 간단하면서 확실한 제어가 가능하다는 점과 전역적인 최적값을 찾을 수 있는 유전 알고리즘을 적용하여 고속제어를 요하는 직류 서보 모터(DC Servo Motor) 운전 시 실시간 파라미터 동조에 적용하였다.

• The Korean Journal of Mycology
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• v.12 no.4
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• pp.141-152
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• 1984

Aspergillus niger van Tieghem was cultured by the method of synchronous and submerged culture. Throughout the culture, sporulation was occured. Highly phosphorylated nucleotides in sporulating mycelia were detected to assure whether the eucaryotic Aspergillus niger produce these substances or not during the differentiation. Phosphorylated nucleotides were extracted from the conidiophore, bearing mycelia and spore forming body, these nucleotides were identified by TLC with P.E.I. cellulose. Guanosine tetraphosphate was found in both phialide forming mycelia and spore forming body. The contents of free amino acids were assayed and its level was found to increase at early stage of sporulation. The effects of 8-azaguanine examined, it was found to prevent spore formation and to made abnormal structure. The effects of inosinic monophosphate and guanosine monophosphate on spore formation were examined, spore formation was enhanced by these nucleotides.

• Journal of Digital Convergence
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• v.13 no.4
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• pp.25-38
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• 2015

In case of current South Korea, the rapid graying is in the progress. Because of it, the increase of elders who live alone causes variety of social, economic and national problems. Especially in the modern city, the health care, safety and maintenance of pleasant and joyful life of elders who live alone are being a big social issue. Even though practical services have been tried at the whole of government approach, the detailed alternatives are insufficient to improve the daily life support and service to approach the information. This research suggests the "ELA Service Model" which actively improves the easy access to information and corresponds to condition and circumstance of elders for providing the ICT-base Elderly Living alone care service. It is a step self-life support service based on fundamental desire of elders which resolves the problem and contributes to establish the active and balanced policy to the elderly.

• The Journal of Korean Society for Radiation Therapy
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• v.24 no.2
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• pp.167-174
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• 2012

Purpose: The respiration is one of the most important factors in respiratory gating radiation therapy (RGRT). We have developed an unique respiratory guidance system using an audio-visual system in order to support and stabilize individual patient's respiration and evaluated the usefulness of this system. Materials and Methods: Seven patients received the RGRT at our clinic from June 2011 to April 2012. After breathing exercise with the audio-visual system, we measured their spontaneous respiration and their respiration with the audio-visual system respectively. With the measured data, we yielded standard deviations by the superficial contents of respiratory cycles and functions, and analyzed them to examine changes in their breathing before and after the therapy. Results: The PTP (peak to peak) of the standard deviations of the free breathing, the audio guidance system, and the respiratory guidance system were 0.343, 0.148, and 0.078 respectively. The respiratory cycles were 0.645, 0.345, and 0.171 respectively and the superficial contents of the respiratory functions were 2.591, 1.008, and 0.877 respectively. The average values of the differences in the standard deviations among the whole patients at the CT room and therapy room were 0.425 for the PTP, 1.566 for the respiratory cycles, and 3.671 for the respiratory superficial contents. As for the standard deviations before and after the application of the PTP respiratory guidance system, that of the PTP was 0.265, that of the respiratory cycles was 0.474, and that of the respiratory superficial contents. The results of t-test of the values before and after free breathing and the audio-visual guidance system showed that the P-value of the PTP was 0.035, that of the cycles 0.009, and that of the respiratory superficial contents 0.010. Conclusion: The respiratory control could be one of the most important factors in the RGRT which determines the success or failure of a treatment. We were able to get more stable breathing with the audio-visual respiratory guidance system than free breathing or breathing with auditory guidance alone. In particular, the above system was excellent at the reproduction of respiratory cycles in care units. Such a system enables to reduce time due to unstable breathing and to perform more precise and detailed treatment.

• The Journal of Natural Sciences
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• v.9 no.1
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• pp.1-7
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• 1997

Calcium/calmodulin-dependent protein kinase II (CaMK-II) is responsible for the phosphorylation of proteins involved in various cellular functions. Since the level of intracellular calcium ($Ca_2+$) oscillate during the cell cycle, it is expected that the activity of CaMK-II is also dependent on the cell cycle. The kinase activity in NIH3T3 cells which were arrested at or released from certain phase of the cell cycle was measured and compared to that in the normally growing asynchronous control cells to investigate whether the activity of this kinase is cell cycle-dependent. Cells were arrested at G0, G1, G1/S, G2/M and M phase, respectively by use of various drugs which do not have any effect on the kinase activity of CaMK-II at G0, G1, G1/s and G2/M phase was similar to that of the control cells, whereas lower at M. Calcium-independent activity of CaMK_II by autophosphorylation was higher at M and, thus, higher autonomy at M, which represented the physiologically relevant activity of CaMK-II. A similar pattern of activity change of the kinase was demonstrated during the cell cycle of synchronized cells which were released from G1 arrest. These results indicate that the activity of CaMK-11 is cell cycle-dependent and is activity during the mitosis.