• Title/Summary/Keyword: 입자 조작

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Dielectrophoresis for Control of Particle Transport: Theory, Electrode Designs and Applications (입자 이동 제어를 위한 유전영동: 이론, 전극 구조 및 응용분야)

  • Lee, Minji;Kim, Ji-Hye;Koo, Hyung-Jun
    • Korean Chemical Engineering Research
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    • v.57 no.2
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    • pp.149-163
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    • 2019
  • Under non-uniform electric field, a directional force along the electric field gradient is applied to matter having permanent or induced dipoles. The transport of particles by the directional force is called dielectrophoresis (DEP). Since the strength and direction of the DEP force depend on parameters, such as permittivity and conductivity of particles and surrounding media, and frequency of the applied AC electric field, particle can be precisely manipulated by controlling the parameters. Moreover, unlike electrophoresis, DEP can be applied to any particles where dipole is effectively induced by electric field. Such a DEP technique has been used in various fields, ranging from microfluidic engineering to biosensor and microchip research. This paper first describes the fundamentals of DEP, and discusses representative microelectrode designs used for DEP study. Then, exemplary applications of DEP, such as separation, capture and self-assembly of particles, are introduced.

A Study on Development of Acoustic Tweezer System Using Standing Waves and Very High Frequency Focused Beams (정상파와 초고주파 집속 빔을 이용한 음향집게시스템의 개발에 관한 연구)

  • Yang, Jeong-Won;Ha, Kang-Lyeol;Kim, Moo-Joon;Lee, Jung-Woo;Shung, K.K.
    • The Journal of the Acoustical Society of Korea
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    • v.27 no.7
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    • pp.357-364
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    • 2008
  • For the purpose of possibility study on development of an acoustic tweezer using standing waves and very high frequency ultrasound focused beams, a system which can manipulate the position of particles in water has been constructed. It can move the particles to near focal point of a focused beam by the radiation force of standing waves, and then the particles would be trapped by the radiating force of the focused beam. The results show that micro sphere particles were trapped well at nodes of the standing waves and their position can be easily manipulated by frequency control. And, even though the radiation force by single focused beam pushes a particle away from the transducer, two focused confronted beams can trap it at near center.

A plan by practically using Low-Energy Compected-Flow mixing installation to improve sendimental and removal efficiency (저에너지형 CF혼화장치를 활용한 침전제거효율 개선 방안)

  • Choi, Gye-Woon;Lee, Joo-Kyung;Ahn, Kyung-Hun;Han, Man-Shin
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.842-846
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    • 2008
  • 원수의 탁질 중에서 입경이 $10^{-1}$mm이상인 것은 보통침전으로 제거가 가능하지만, 입경이��$10^{-3}mm$이하가 되면 일반적으로 콜로이드입자라고 총칭하며 그대로의 상태로서는 거의 침강되지 않을 뿐만 아니라 급속여과기구에서도 포착되지 않는다. 따라서 급속여과 방식에서는 이와 같은 탁질을 효과적으로 제거하기 위한 전처리로서 응집조작으로 인한 콜로이드상의 탁질을 플록화하여 약품침전이나 급속여과에서 포착되도록 탁질의 성상을 변화시키는 조작이 반드시 필요하다. 또한 양호한 플록을 효과적으로 형성시키는 약품혼화와 플록형성 등을 강구해야 한다. 이에 본 연구에서는 현재 국내에서 운영하고 있는 정수처리시스템의 일부인 혼화지내에 혼화지점의 단면적을 축소시켜 약품혼화효과를 극대화하고 혼화기의 소요동력을 감소시켜 혼화효과를 개선하며 혼화지내 혼화기 운용의 비용 절감 효과를 증가시키기 위한 저에너지형 CF혼화장치를 개발하는데 연구 목적이 있다. 연구결과 CF혼화장치의 설치시 약품 투입 위치에 따라 $2{\sim}6%$정도의 탁도제거율의 상승과 슬러지 높이의 차이를 보이는 것으로 나타났으며 이 실험 결과 약품투입장소에서 혼화지의 Compact화로 인해 급속 혼화를 이룰 경우 더 많은 플록화로 인해 탁도 제거율이 높아지는 것을 알 수 있다.

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Grinding Kinetics of Calcite, Pyrophyllite and Talc During Stirred Ball Milling - Consideration of Selection Function (교반 볼밀에 의한 방해석, 납석, 활석의 분쇄 시 분쇄속도론에 관한 연구 - 선택함수의 고찰)

  • Choi, Hee-Kyu;Kim, Seong-Soo;Hwang, Jin-Yeon
    • Journal of the Mineralogical Society of Korea
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    • v.20 no.2 s.52
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    • pp.135-145
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    • 2007
  • The needs for the ultra fine particles have been increased in preparation field of raw powders such as fine ceramics and high functional products. In this study, a series of wet grinding experiments were carried out on inorganic powders such as calcite, pyrophyllite and talc by a stirred ball mill. The particle size distribution of ground products of each test material fur a given grinding time was found to be expressed by the grinding rate (selection function) which was obtained from the grinding kinetics analysis. The median diameter decreased from 6.49 to $0.47{\mu}m$ in calcite, and decreased from 3.91 to $1.14{\mu}m$ in pyrophyllite. However, in talc, median diameter was decreased a little bit from 10.30 to $6.67{\mu}m$. The grinding rate changing on calcite and pyriphyllite were similar at the same conditions. However, in the case of talc, it was observed that the grinding rate was not increased compared to other samples.

The Production of Protein-loaded Poly(lactide-co-glycolide) Microparticles using Supercritical Carbon Dioxide (초임계 PGSS 법을 이용한 Poly(lactide-co-glycolide)와 단백질의 마이크로복합체 제조에 관한 연구)

  • Song, Eun-Seok;Jung, Heon-Seop;Lee, Hanho;Kim, Jae-Duck;Kim, Hwayong;Lee, Youn-Woo
    • Clean Technology
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    • v.12 no.2
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    • pp.53-61
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    • 2006
  • A PGSS (Particles from Gas Saturated Solutions) process designed to generate nano-particles using supercritical fluids has been conducted for the fabrication of Poly(lactide-co-glycolide) (PLGA) microparticles that encapsulate a protein drug. It is demonstrated that the polymer and the dry powder of a protein can be mixed under supercritical carbon dioxide conditions and that the protein component retains its biological activity. In this experiment, the mixture of polymer which is plasticized and dry powder protein was sprayed to form solid polymer that encapsulate the protein. It is found that supercritical fluid process give fine tuning of particle size and particle size distribution by simple manipulations of the process parameters. Porous particles were formed with irregular shape. Protein encapsulated in the polymer was found to have enzymatic activity without significant loss of its initial value.

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Contraction of Alpha-nickel Hydroxide Layers by Excess Coulombic Attraction of Anions (전기화학적으로 형성된 알파 상 니켈 수산화물의 층간 거리에 미치는 음이온의 영향 연구)

  • Kim, Gwang-Beom;Ganesh Kumar, V.;Bae, Sang-Won;Lee, Jae-Seong
    • Journal of the Korean Chemical Society
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    • v.50 no.2
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    • pp.141-152
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    • 2006
  • In this study computer assisted instruction materials for the ‘Solution' chapter in high school chemistry II textbook were developed based on a view of particle and analyze the effect of the materials on 10th and 11th high school students. The contents of developed materials are dissolution, vapor pressure, the change of boiling point and freezing point, osmosis, and so on which are the major contents of Solution chapter in high school chemistry II textbook. Materials were developed with using animation and simulation for students understanding of the phenomena with a particle view point. Many phenomena in a solution were not simplified by colligative property of solution, but tried to explain by the concept of attraction between solute and solvent molecules. This computer assisted learning materials were developed using Flash 5.0 and Flash 6.0 Action Script. Educational effects of the materials on 10th and 11th grade students represented statistically meaningful increase of concept understanding. Especially the materials were effective to the transition stage or formal stage students in 10th grade and formal stage or the natural science major students in 11th grade.

Finite Element Analysis of a Particle Manipulation System Using Ultrasonic Standing Wave (정재초음파를 이용한 입자제어 시스템의 유한요소해석)

  • Cho, Seung-Hyun;Park, Jae-Ha;Ahn, Bong-Young;Kim, Ki-Bok
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.20 no.1
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    • pp.3-9
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    • 2010
  • Micro particles in fluid can be manipulated by using ultrasonic standing wave since the ultrasound makes particles move by means of its acoustic radiation force. This work concerns the micro particle manipulation system using ultrasonic standing wave which consists of a microchannel, a reflector, and an ultrasonic transduer. In the present system, the effects of the structural elements should be carefully considered to comprehend the system and find the optimal operational condition. In this investigation, finite element analysis was employed to analyze the system. Some interesting characteristics on the reflector thickness, the channel width, and the operational frequency were observed. Several experimental results were compared with the analytic results. Consequently, this work solidifies the importance of those system parameters and reveals the possibility of various applications of the particle manipulation using ultrasonic standing wave.

Finite Element Analysis of a Particle Manipulation System Using Ultrasonic Standing Wave (정재초음파를 이용한 입자제어 시스템의 유한요소해석)

  • Cho, Seung-Hyun;Park, Jae-Ha;Ahn, Bong-Young;Kim, Ki-Bok
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2009.04a
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    • pp.565-570
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    • 2009
  • Micro particles in fluid can be manipulated by using ultrasonic standing wave since the ultrasound makes particles move by means of its acoustic radiation force. This work concerns the micro particle manipulation system using ultrasonic standing wave which consists of a microchannel, an adaptive layer, a reflector, and an ultrasonic transduer. In the present system, the effects of the structural elements should be carefully considered to comprehend the system and find the optimal operational condition. In this investigation, finite element analysis was employed to analyze the system. Some interesting characteristics on the reflector thickness, the channel width, and the operational frequency were observed. Several experimental results were compared with the analytic results. Consequently, this work solidifies the importance of those system parameters and reveals the possibility of various applications of the particle manipulation using ultrasonic standing wave.

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Measurement of Adsorption Characteristic Using a Quartz Crystal Resonator (수정진동자를 이용한 흡착특성의 측정)

  • Kim, Byoung Chul;Sung, Ick Gi;Yamamoto, Takuji;Kim, Young Han
    • Korean Chemical Engineering Research
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    • v.47 no.3
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    • pp.368-372
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    • 2009
  • A technique to measure the adsorption characteristic of surface area and pore size distribution is proposed and its performance is examined. While the existing equipment utilizes liquid nitrogen, the proposed uses carbon dioxide at the room temperature leading to the small measuring device with easy operation and short measurement time. The performance of the device has been examined with micro-particle carbon cryogel and bamboo activated carbon. The results from the proposed device compared with those of the adsorption apparatus indicate that the measurement of meso-porous material is comparable but micro-porous material gives some error.

Development of portable single-beam acoustic tweezers for biomedical applications (생체응용을 위한 휴대용 단일빔 음향집게시스템 개발)

  • Lee, Junsu;Park, Yeon-Seong;Kim, Mi-Ji;Yoon, Changhan
    • The Journal of the Acoustical Society of Korea
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    • v.39 no.5
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    • pp.435-440
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    • 2020
  • Single-beam acoustic tweezers that are capable of manipulating micron-size particles in a non-contact manner have been used in many biological and biomedical applications. Current single-beam acoustic tweezer systems developed for in vitro experiments consist of a function generator and a power amplifier, thus the system is bulky and expensive. This configuration would not be suitable for in vivo and clinical applications. Thus, in this paper, we present a portable single-beam acoustic tweezer system and its performances of trapping and manipulating micron-size objects. The developed system consists of an Field Programmable Gate Array (FPGA) chip and two pulsers, and parameters such as center frequency and pulse duration were controlled by a Personal Computer (PC) via a USB (Universal Serial Bus) interface in real-time. It was shown that the system was capable of generating the transmitting pulse up to 20 MHz, and producing sufficient intensity to trap microparticles and cells. The performance of the system was evaluated by trapping and manipulating 40 ㎛ and 90 ㎛ in diameter polystyrene particles.