• The Monthly Diabetes
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• s.256
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• pp.60-61
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• 2011

당뇨병으로 인한 태아의 위험은 당뇨병의 유전요인보다는 임신부의 대사 장애에 의한 것으로 당뇨병 형태에 따른 태아의 위험 차이는 없는 것으로 추축할 수 있다. 그러나 제 1형 당뇨병임신부는 케톤산혈증이 발생할 가능성이 높고 케톤산 혈증이 발생하면 태아 사망의 가능성도 높아진다. 또 제 1형 당뇨병임신부는 당뇨병성 혈관합병증이 동반될 가능성이 많아 자기의 주 수 보다 체중이 미달되는 경우와 조산 및 임신 중 고혈압질환이 발생할 위험성이 높아진다. 제 2형 당뇨병임산부는 임신부가 비만일 경우 거대아 출산 및 임신 중 고혈압질환이 발생할 위험이 높아진다. 그러나 대부분의 합병증은 임신 전과 임신기간 동안 양호한 혈당조절로 감소시킬 수 있다.

• 건강소식
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• v.22 no.4 s.233
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• pp.16-19
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• 1998

• The Monthly Diabetes
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• s.15
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• pp.8-12
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• 1991

• Journal of agricultural medicine and community health
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• v.38 no.1
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• pp.14-24
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• 2013

Objectives: Pregnant women in rural areas do not have access to sufficient obstetric services in their own communities due to the shortage of obstetricians. Therefore, most of these women must seek obstetrician outside of their communities. The purpose of this study was to investigate the relationship between obstetric complications and accessibility to local obstetric care in Korea. Methods: This study was an ecological study in which the unit of analysis was an administrative district. Using Korea National Health Insurance Corporation data, the total number of deliveries and the delivery proportion within and outside of the community from 2001 to 2008 were calculated for 232 administrative districts nationwide. Three outflow levels were categorized based on each district's out-of-community delivery proportion: high outflow (upper one third), moderate outflow (middle one third), and low outflow (lower one third). In addition, three obstetric complication rates (the rate of complications following abortion, ectopic and molar pregnancy, the abortion rate, and the eclampsia rate) were calculated for the 232 districts. One-way ANOVA and multivariate linear regression were used to evaluate obstetric complications among the three outflow levels. Results: The high outflow districts had higher rates of eclampsia and complications following abortion, ectopic, and molar pregnancy compared to the other districts (ANOVA, p<0.05). However, there was no significant difference in the abortion rate among the three groups. Multiple linear regression analysis showed that high outflow districts were statistically significant in the rate of complications following abortion, ectopic and molar pregnancy and eclampsia rate after adjusting for local tax per capita (p<0.01). Conclusion: These results indicate that poor access to local obstetric care correlate with poor obstetric outcomes (delayed or excessive bleeding, embolism, genital tract or pelvic infection, shock or other complications following abortion and ectopic or molar pregnancy, or eclampsia).

• Journal of Genetic Medicine
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• v.6 no.1
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• pp.74-80
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• 2009

Purpose: To assess the value of first-trimester pregnancy-associated plasma protein-A (PAPP-A), nuchal translucency (NT) and second-trimester alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), and inhibin-A in predicting pregnancy complications other than fetal aneuploidy. Materials and Methods: A retrospective study in 3,121 singleton pregnancies with integrated testing was performed at Kangnam CHA hospital between January 2005 and December 2006. Baseline characteristics, pregnancy outcomes, and serum marker levels were obtained by review of the medical records. We analyzed the data to identify associations between the integrated screening markers and adverse pregnancy outcomes. Statistical analyses were performed with the SPSS program. Results: In preterm labor and preeclampsia, high AFP, hCG, and inhibin-A levels and low PAPP-A and NT levels were found to be significantly correlated (P<0.05). Elevated second-trimester inhibin-A levels were associated with preeclampsia (odds ratio 2.843), low birth weight (odds ratio 1.446), and preterm labor (odds ratio 1.287), and while decreased first-trimester PAPP-A levels were associated with preeclampsia (odds ratio 0.51) and preterm labor (odds ratio 0.75). Conclusion: First- and second-trimester maternal serum markers screening can be used for predicting high-risk pregnancies.

• The Monthly Diabetes
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• s.253
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• pp.32-33
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• 2010

당뇨병이 여성에게 특히 더 많이 생기는 것은 아니다. 하지만 남성과는 다른 당뇨병의 위험요소를 여성은 가지고 있다. 임신이 첫 번째 요인이요, 폐경후 호르몬 변화가 두 번째 요인이다. 이 때문에 당뇨가 있는 여성은 결혼 생활과 임신, 출산 등에 대하여 불안을 느끼고 걱정을 많이 한다. 그들의 고민을 들어보자.

• Clinical and Experimental Pediatrics
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• v.46 no.5
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• pp.447-453
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• 2003

Purpose : This study was performed to compare complications and perinatal factors according to the birth weight groups in the infants of diabetic mothers(IDM). Methods : Three hundred and one singleton diabetic mothers and their babies of more than 30 weeks' gestational age admitted in the department of Pediatrics, Chonnam University Hospital from January 1996 to March 2002 were enrolled. Complications and perinatal factors were compared between large for gestational age(LGA) and appropriated for gestational age(AGA) infants. Results : Hypomagnesemia was observed in 37.5%, jaundice in 21.3%, hypoglycemia in 11.1%, hypocalcemia in 7.0%, and birth injury in 19.6%. Congenital anomaly was noted in 24.9% with cardiovascular anomaly most commonly. In the LGA group, the frequencies of jaundice, hypoglycemia, tachypnea, and birth injuries were higher, and the interventricular septum was thicker than the AGA group. In the LGA group, Cesarean section rate, maternal height, weight before pregnancy, weight gain during pregnancy, and the incidence of unawareness of gestational DM were significant compared with the AGA group. Conclusion : In the LGA group, the frequencies of jaundice, hypoglycemia, tachypnea, and birth injuries were higher, and the interventricular septum was thicker than the AGA group. In the LGA group, maternal height, weight before pregnancy and weight gain during pregnancy were larger, and the incidence of unawareness of gestational DM was higher compared with the AGA group. These results suggest that careful examination and management are needed to detect the high risk, pregnant DM mothers with possible LGA babies.

• Clinical and Experimental Reproductive Medicine
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• v.3 no.2
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• pp.13-27
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• 1976

• Journal of the Korean Society of Radiology
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• v.83 no.5
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• pp.1121-1127
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• 2022

Endometriosis-related symptoms are believed to be alleviated during pregnancy. However, pregnancy complications, such as pseudoaneurysm of the uterine artery, rupture of ovarian or uterine vessels, and intraabdominal bleeding from decidualized deep infiltrating endometriosis (DIE) lesion have been rarely reported. Owing to the potential risk of rupture and resultant life-threatening complications, proper diagnosis and close monitoring of decidualized endometriotic lesion are very important despite its low relative risk. Till date, massive vaginal bleeding from decidualized rectovaginal DIE during pregnancy has not been in English literatures. Here, we present the first case of spontaneous massive vaginal bleeding due to decidualized rectovaginal DIE that occurred in the late third trimester of pregnancy.

• 대한생식의학회:학술대회논문집
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• 2006.11a
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• pp.67-80
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• 2006

비만 특히 복부비만은 여성의 임신 및 출산에 많은 악영향을 미친다. 비만이 가임력에 영향을 미치는 기전은 명확히 밝혀지지는 않았지만, functional hyperandrogenism과 insulin resistance에 수반된 hyperinsulinemia가 중요한 역할을 하리라 여겨진다. 또한 지방조직은 활발하게 대사 작용이 일어나는 장소로서 steroid hormone을 modification 시키고, 여러 가지 adipokine들을 분비시키는데 이런 지방조직의 분비물들은 생식계에 영향을 미친다. 비만이 생식계에 미치는 영향은 간략히 다음 표와 같이 정리할 수 있다 (Table 3). 특히 PCOS 환자에서 비만은 hyperinsulinemia에 의한 난소의 steroidogenesis 증가와 SHBG의 감소에 연관되어 hyperandrogenism 과 무배란의 원인으로 작용한다. 비만은 약물에 의한 배란유도 및 체외수정의 성공률 또한 떨어뜨리며， 임신이 되더라도 자연 유산, 조산, 임신성 당뇨, 임신성 고혈압 등의 위험은 높인다. 이와 같이 최근 급격히 증가하는 비만은 여성의 건강 특히 생식계에 많은 문제를 야기시킨다. 특히 청소년기의 비만은 성인이 된 뒤 PCOS로 발전하여 불임, 심혈관 질환 등과 같은 많은 합병증을 일으킬 수 있으므로 세심한 주의를 기울여야 하겠다.