• Title/Summary/Keyword: 임상 경과

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Clinical Course of Probable Idiopathic Pulmonary Fibrosis (임상적으로 진단된 특발성 폐섬유화증의 임상경과)

  • Kyung, Sun Young;Park, Cheul Hee;Lim, Young-Hee;An, Chang Hyeok;Lee, Sang Pyo;Park, Jeong Woong;Jeon, Kyeongman;Lee, Byoung-Hoon;Chung, Man Pyo;Jeong, Sung Hwan
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.1
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    • pp.77-85
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    • 2005
  • Background : According to the 2002 consensus report of the American Thoracic Society/European Respiratory Society (ATS/ERS), idiopathic pulmonary fibrosis (IPF) was classified as biopsy proven or probable IPF. Probable IPF is defined as those with distinctive features that allow for a confident diagnosis of IPF/usual interstitial pneumonia (UIP) within an appropriate clinical setting. The determination of the clinical course of probable IPF, as diagnosed by the ATS/ERS criteria, was studied. Methods : Between March 1995 and August 2002, 36 patients with probable IPF, from two tertiary referral hospitals, were enrolled in this study. The clinical characteristics, prognostic factors and treatment efficacy of these patients were retrospectively evaluated. Results : The mean age of the subjects was $65{\pm}6$ years. The one and 3 year survival rates were 82.4 and 50.3%, respectively, and a median survival period of 42.0 months. The total cell count of bronchoalveolar lavage was higher in the death than the survival group (p<0.05). No survival benefits were found in the cytoxan and steroid treatment groups compared with other treatment groups. Conclusion : These results suggest that the clinical course of probable IPF may be similar to that of biopsy-proven UIP. However, atypical patients must undergo an open lung biopsy for confirmation of the diagnosis.

Endoscopic Removal of Esophageal Foreign Body in a Moluccan Cockatoo (Cacatua moluccensis) (몰루칸 앵무새에서의 내시경을 이용한 식도 이물 제거 일례)

  • Lee, So-Young;Yoo, Jong-Hyun;Park, Chul;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.24 no.1
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    • pp.29-31
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    • 2007
  • A thirty-month-old male Moluccan Cockatoo (Cacatua moluccansis) with mild anorexia was referred. Through physical examination, fireign body was palpated at the crop region. Radiopaque, lineal foreign body was visualized on the lateral radiographs of the thoracic esophageal region. The patient was definitively diagnosed esophageal foreign body which is ingested feeding tube. The foreign body removal was undertaken using a flexible endoscope and a grasping forcep without any other complications. This case report demonstrated that successful esophageal foreign body removal with endoscopy in birds.

Laparoscopic Treatment of Ovarian Remnant Syndrome in a Queen (고양이에서 발생한 난소 잔존 증후군에 대하여 복강경을 이용한 치료 증례 1)

  • Park, Jiyoung;Lee, Hae-Beom;Jeong, Seong Mok
    • Journal of Veterinary Clinics
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    • v.32 no.6
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    • pp.514-518
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    • 2015
  • A 1-year-old, 2.35 kg spayed female American short hair cat was referred with episodic signs of heat at 3 months after ovariohysterectomy. Through the screening tests, bilateral cystic, ovary like masses were shown at the caudal to both kidneys with high serum estradiol concentration. It was considered that the patient was suffered from ovarian remnant syndrome. Laparoscopic exploration was performed, and each of mass lesions was resected by ultrasonic scalpel. Patient was recovered favorably and has been doing well without recurrence of estrus signs until 2 years after surgery.

A Study on the Development and Application of Korean Medical Critical Pathway of Lumbar Disc Herniation in Four Different Medical Associations (요추 추간판 탈출증의 4종 한의표준임상경로(CP) 개발 및 시범적용 연구)

  • Kim, Jung-Hyun;Chae, Sang Yeup;Ko, Min-Jung;Jo, Min-Gi;Jang, Jun-Yeong;Kim, Jun Yeon;Kim, Ha-Na;Park, Kyeong Ju;Hwang, Ji-Min;Goo, Bonhyuk;Park, Yeon-Cheol;Baek, Yong-Hyeon;Nam, Sang-Soo;Seo, Byung-Kwan
    • The Journal of Korean Medicine
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    • v.42 no.3
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    • pp.1-8
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    • 2021
  • Objectives: A critical pathway defines the optimal care process, sequencing and timing of intervention by multi-disciplinary health care teams for a particular diagnosis and procedure. It plays an important role as a cost-effective health care delivery system and a tool for quality control of medical and dental services by means of standardizing medical practices. The aim of this study is to investigate the satisfaction of patients and medical staff after implementation of a critical pathway for Korean medical treatment of lumbar disc herniation in integrative medical. Methods and Results: The pre-critical pathway group included 3 patients who underwent the implementation procedure from October 2020. All three patients have successfully been applied critical pathways during inpatient and outpatient treatment. Additionally, medical staff members were satisfied with the usefulness of the critical pathway. Conclusions: The implementation of critical pathway for the Korean medical treatment with lumbar disc herniation in integrative medical hospital can appraise possible applicability in actual clinical field.

Expression of VEGF, p53, Apaf-1 and Caspase-9 in Head and Neck Squamous Cell Carcinoma (두경부 편평세포암에서 VEGF, p53, Apaf-1 and Caspase-9의 발현)

  • Lee, Sung Hak;Kang, Yeo Ju;Jo, Ui Ju;Lee, Youn Soo;Kang, Chang Suk
    • Korean Journal of Head & Neck Oncology
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    • v.28 no.2
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    • pp.107-113
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    • 2012
  • 배 경 편평상피암은 두경부의 악성종양 중 가장 흔하며, 임상적인 경과가 불량하다. 따라서 나쁜 예후를 가지는 환자군을 조기에 선별하여 더 적극적인 치료의 시행을 결정짓는 표지자의 필요성이 대두된다. 우리는 일련의 두경부 편평세포암 검체에서 몇몇 분자 표지자의 예후적 유용성을 평가하고자 하였다. 방 법 23예의 두경부 편평세포암 검체를 대상으로 VEGF, p53, Apaf-1, caspase-9의 발현과 몇몇 임상병리학적 지표들간의 연관성을 면역조직화학염색을 통해 조사하였다. 결 과 환자군은 남성이 더 많았으며 평균연령은 63.7세였다. 1기가 5예, 2기가 2예, 3기가 8예, 4기가 8예였다. 평균생존기간은 37.3개월이었다. VEGF단백 발현은 종양의 크기와 통계적으로 유의한 연관성을 보였다. 이와 더불어 VEGF단백 발현은 병기, 그리고 림프관 침습과 연관적인 경향성을 보였다. 그러나 VEGF단백 발현과 생존기간과는 관련성이 없었다. 또한, Apaf-1과 caspase-9의 단백발현은 다른 임상지표, 환자의 생존기간과는 관련이 없었다. 결 론 VEGF단백 발현은 두경부 편평세포암 환자에서 나쁜 임상경과를 예측할 수 있게 하는 표지자로서의 역할을 할 수 있다. 또한 본 연구는 두경부 편평세포암에서 별로 연구되지 않은 Apaf-1과 caspase-9의 발현상태를 밝힌 점에서 의의가 있다.