• Title/Summary/Keyword: 임상 경과

Search Result 2,548, Processing Time 0.038 seconds

A Therapeutic Experience of Congenital Bilateral Neuroblastoma (선천성 양측성 신경모세포종의 치료경험 1례)

  • Seo, Yeon Kyong;Kim, Heung Sik;Kwon, Kun Young;Lee, Hee Jung;Koo, Hong Hoe
    • Clinical and Experimental Pediatrics
    • /
    • v.46 no.12
    • /
    • pp.1279-1282
    • /
    • 2003
  • Neuroblastoma is the most common intraabdominal malignant tumor of childhood, with 40% arising from the adrenal gland. Bilateral adrenal involvement from synchronous development or metastatic spread of tumor is rarely seen in children with neuroblastoma. The patient was born with a spontaneous vaginal delivery. Birth weight was 3,200 g. Fetal ultrasonography showed a left adrenal cystic mass. At two weeks of age, she was admitted due to a massive abdominal distension and tachypnea. Percutaneous ultrasonography guided biopsy of the left adrenal mass was performed. The result of the biopsy was neuroblastoma. Vincristine and cyclophosphamide were administerd intravenously and 450 cGy of irradiation was added. Left adrenalectomy was accomplished and postoperative course was uneventful. The patient received cancer chemotherapy with a combination of carboplatin, ifosfamide and VP-16 and is now being followed up for three months. We have experienced a case of congenital bilateral neuroblastoma and report the case with brief review of related literatures.

In vitro Antioxidant Activity of Cooked Rice Containing Various Seaweeds (다양한 해조류를 첨가하여 제조한 밥의 in vitro 항산화 활성)

  • Choi, Youngjin;Kim, Soomin;Lee, Seogyeong;Kim, Hyun Jung;Lim, Sangbin;Oh, Myung-Cheol
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.53 no.3
    • /
    • pp.388-394
    • /
    • 2020
  • An emerging interest in healthy eating has led to an increase in the consumption of rice mixed with various types of grains. Cooked rice was prepared with five different seaweeds, Hizikia fusiformis, Sargassum fulvellum, Enteromorpha compressa, Undaria pinnatifida, and Gracilaria verrucosa, and the antioxidant activity was measured. In addition, the antioxidant activities of 80% ethanol and methanol extracts of the five seaweeds were compared. Total phenolic content (TPC), total reducing power (TRP), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) cation radical scavenging activities of the ethanol extracts were higher than those of the methanol extracts. The TPC of raw seaweed ethanol extracts was from 7.58 to 26.27 mg gallic acid equivalent (GAE)/g. The antioxidant activities of both extracts of Hizikia fusiformis were the highest among the five seaweeds, and the antioxidant activities of the cooked rice were lower than those of the raw seaweed extracts. The DPPH radical scavenging activities of cooked white rice, mixed grains, barley, and a mixture of white rice and barely added with Hizikia fusiformis, Sargassum fulvellum and Undaria pinnatifida were 3.17, 23.12, 31.11 and 10.66%, respectively. These results demonstrate the addition of seaweeds to cooked rice helps to improve the antioxidant activity compared to white rice alone.

An Outbreak of Swine Dysentery in Korea : Clinical Aspects and Pathology (돼지 적리(赤痢)의 발생보고(發生報告) : 임상(臨床) 및 발생학적(發生學的) 소견(所見))

  • Bak, Ung-Bok;Moon, Moo-Hong;Park, Ki-Seo
    • Korean Journal of Veterinary Research
    • /
    • v.16 no.1
    • /
    • pp.27-34
    • /
    • 1976
  • 악상남도(惡尙南道) 김해군(金海郡) S 양돈장(養豚場)에서 1975년 4월 하순부터 5월 하순 사이에 사육돈(飼育豚) 1,200두중 약 350두에서 출혈성하리(出血性下痢)를 주증(主症)으로 하는 전염성(傳染性)이 강한 소화기질환(消化器疾患)이 발생하였다. 환돈(患豚)은 7주령(週齡)에서부터 14주령(週齡)까지에서 가장 많이 발생하고 급성(急性) 또는 아급성(亞急性)으로 경과하였으며 다량의 황백색(黃白色), 수양하리(水樣下痢)를 발하다가 황갈색(黃褐色), 포말성하리(泡沫性下痢) 또는 암적갈색(暗赤褐色) 점액성하리(粘液性下痢)를 나타내었다. 육안적(肉眼的) 병변(病變)은 대장(大腸)에 한하였으며 카타아르성(性), 출혈성(出血性) 내지 괴사성장염(壞死性腸炎)을 시현(示顯)하였으며 괴사(壞死)는 광범(廣凡)하나 표재성(表在性)이고 어떤 예에서는 결장점막(結腸粘膜) 속에 대소(大小)의 미세결절(微細結節)이 밀발(密發)한 것이 특징이었다. 조직학적검사(組織學的檢査)에서는 대장점막(大腸粘膜)에 현저한 배세포증식(杯細胞增殖), 울혈(鬱血) 및 원형세포침윤(圓形細胞浸潤)과 더불어 표재성괴사(表在性壞死)가 관찰되었고 상기(上記) 결절(結節)은 장선(腸腺) 속에 점액(粘液), 섬유소(纖維素) 및 붕괴세포(崩壞細胞)가 축적되어 선와(腺窩)가 확장되고 피복상피(被覆上皮)의 이형성(異形成)(dysplasia)을 일으키고 있음이 판명되었다. 병변부(病變部)의 세균염색(細菌染色)에 의하여 대형(大型) Spirocheta와 Vibrio 고균(孤菌)이 무수(無數)히 발견되었고 Spirocheta가 병변형성(病變形成)에 더 밀접하게 관련되어 있음이 밝혀졌다.

  • PDF

Effects of Doula Support in LDR (Labor-Delivery-Recovery) on Anxiety, Labor Pain, and Perceived Childbirth Experience of Primiparas (일개대학병원 가족분만실에서 듈라(Doula)식 분만지지간호가 초산부의 불안, 분만통증 및 분만경험지각에 미치는 효과)

  • Park, Kwang Hee;Choi, Jung Sun;Lee, Jeong Hwa;Jin, Bo Kyung
    • Journal of Korean Clinical Nursing Research
    • /
    • v.14 no.3
    • /
    • pp.87-97
    • /
    • 2008
  • Purpose: The purpose of this study was to evaluate the effects of Doula support during labor on anxiety, labor pain, and perceived childbirth experience of primiparas. Method: Of 65 primiparas who were hospitalized in LDR from March 1 to September 30, 2007. 32 women were placed in the Doula group and 33 in the control group. VAS was used to measure the degree of labor pain and anxiety in the latent, active, and transitional phases. Perceived childbirth experience was measured within 2 hours after birth. Results: The Doula group had a significantly lower anxiety level than the control group in the active phase (t=-2.13, p=.04) and the transitional phase (t=-3.99, p=.000). The degree of labor pain of the Doula group was significantly lower than that of the control group for the active phase (t=-3.10, p=.003) and the transitional phase (t=-7.24, p=.000). Also, There was no significant difference in perceived childbirth experience between the two groups (t=.19, p=.85). Conclusion: The results of this study show Doula support in LDR decreases not only anxiety of primiparas but also labor pain in the active and transitional phases. Therefore Doula support by nurses in LDR can be a useful intervention during childbirth.

  • PDF

CERVICOFACIAL NECROTIZING FASCIITIS;CASE REPORT (경안면 괴사성 근막염;증례보고)

  • Park, Kwan-Soo;Jeong, Ki-Hoon;Kim, Hyo-Eon;Jeong, Jeong-Kwon;Yoon, Kyu-Ho;Jeon, In-Seong
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.23 no.1
    • /
    • pp.77-81
    • /
    • 2001
  • Necrotizing fasciitis is defined as infectious disease showing extensive necrosis of the superficial fascia with widespread involvement of the surrounding tissues and concurrent systemic toxicity. It is found commonly in the extremities, the trunk and the perineum, but shows extremely rare occurrence in the well vascularized area such as head and neck area. Occurred in the head and neck area, it is called "cervicofacial necrotizing fasciitis" (CFNF). It is a fatal disease which carries a mortality rate up to 60%. Early diagnosis, aggressive surgical debridement of necrotic tissues and massive antibiotics therapy are essential for achieving a favorable outcome. We present a case of cervicofacial necrotizing fasciitis in 35-year-old male patient with literature review.

  • PDF

Comparison of computer-based treatment prediction with true results in bimaxillary protrusion cases (치조성 양악 전돌 환자에서 컴퓨터를 이용한 치료 결과 예측의 정확성)

  • Lee, Rhi-na;Lim, Yong-Kyu;Lee, Dong-Yul
    • The korean journal of orthodontics
    • /
    • v.32 no.3 s.92
    • /
    • pp.155-163
    • /
    • 2002
  • This study was performed to assess the accuracy of computer-based treatment prediction for soft tissue profile using Quick Ceph Image $Pro^{TM}\;&\;Quick\;Ceph\;2000^{TM}$ in bimaxillary protrusion cases. The Ore- and post-treatment lateral cephalograms of 21 female adults treated by low first premolar extraction were imaged and 9 landmarks and 27 specific soft tissue mesurements were digitized for comparing actual treatment results with computer simulations. The results of this study showed that Quick Ceph Image $Pro^{TM}\;&\;Quick\;Ceph\;2000^{TM}$ tends to overestimeate horizontal changes and underestimate vertical changes. In the computer simulation, upper lip showed rolling tendency. The upper lip measurements were disposed to be regular direction hut lower lip measurements were varied case by case even if it was statistically insignificant.

A Study on Synovial Fluid Analysis of Chronic TMD and Effects of Pumping Technique (만성 악관절장애환자의 활액분석 및 악관절 도약술의 효과에 관한 연구)

  • 김용우;김영구;연태호
    • Journal of Oral Medicine and Pain
    • /
    • v.22 no.2
    • /
    • pp.241-252
    • /
    • 1997
  • 본 연구는 임상검사 및 방사선 사진상 악관절장애로 진단된 환자중 물리치료,악관절 안정장치 등의 보존적 치료방법을 시행하였으나 증상의 개선이 별로 없는 퇴행성 관절질환이나 중등도의 개구제한을 가진 환자를 대상으로하여 aspirin을 이용한 활액성분 분석 및 악관절 도약술과 sodium hyaluronate의 주입을 시행한후 이에 따른 치료결과를 평가하기 위하여 시행되었다. 평균연령이 31.2세(21-42세)인 11명의 악관절 장애환자를 대상으로 하였다. 악관절 도약술과 sodium hyaluronate의 주입은 악관절의 동통과 개구제한의 해소를 위해 시행되었으며 그 결과를 시술전, 시술 즉시, 시술 1주후 및 4주후로 나누어 분석하였으며 활액 채취시 생리식염수의 희석에 의한 활액성분의 농도 변화에 따른 오차를 막고자 활액과 혈액내의 aspirin의 농도차를 이용하여 정확한 활액 성분농도를 측정하였다. 이상의 연구를 통하여 다음과 같은 결론을 얻었다. 1. 전체 환자의 생리식염수에 의한 악관절 활액의 희석계수는 1.4-12.9(5.5$\pm$4.2)로 상당히 넓은 범위를 나타내었다. 2. 만성 폐구성 과두걸림 환자군(n=7)의 생리식염수에 의한 활액의 희석계수 (6.2$\pm$3.5)는 퇴행성 관절질환을 갖는 환자군(4.4$\pm$5.7, n=4)과 유의한 차이가 없었다. 3. 만성폐구성 과두걸림군과 퇴행성 관절 질환군간의 활액성분의 농도는 유의한 차이가 없었으나 희석계수를 이용한 수정된 Hyaluronic acid와 총단백질의 농도는 만성 폐구성 과두걸림군의 경우에서 유의하게 더 높게 나타났다. 4. 악관절 도약술과 sodium hyaluronate의 주입 직후 만성 폐구성 과두걸림 환자군의 경우 평균 8.3mm의 추가적인 개구 증가로 유의한 차이가 관찰되었고 퇴행성 관절질환의 경우 평균 1.3mm의 추가적인 개구증가가 있었으나 유의한 차이가 관찰되지 못했다. 5. 시술전, 시술 1주후 및 4주후의 여러 검사항목을 비교한 결과 두 군에서 모두 시간의 경과에 따라 기능이상 및 동통 감소의 경향을 나타내었으나 유의하지는 않았으며 만성 폐구성 과두걸림의 경우 기능장애지수(dysfunction index) 와 최대개구시 동통의 정도는 시술전과 시술 4주후간에 유의한 차이가 관찰되었다.

  • PDF

Clinical Effect of Arthrocentesis for Patients with Disc Displacement without Reduction of Temporomandibular Joint : Report of Cases (측두하악관절의 비정복성 관절원판변위 환자에 대한 관절강 세정술의 임상효과 : 증례보고)

  • Kim, Cheul;Kim, Young-Jun
    • Journal of Oral Medicine and Pain
    • /
    • v.31 no.2
    • /
    • pp.177-183
    • /
    • 2006
  • The management of refractory pain and limitation of mouth opening in the temporomandibular joint (TMJ) is both challenging and controversial. Arthrocentesis is a simple technique and it can be used instead of more invasive surgical procedures for patients who failed to conventional conservative treatments. The patients in this case report had complained persistent severe pain and restricted mandibular movement of TMJ, although they had been treated with conservative therapy, e.g., stabilization splint therapy, behavioral therapy, physical therapy, pharmacological therapy. Therefore we employed arthrocentesis for these patients, and they showed significant reduction of pain and improvement of mandibular movement after repetitive arthrocentesis. We recommend arthrocentesis as an effective, minimally invasive technique for patients with continuing severe pain and restricted mobility in the TMJ that is unresponsive to conservative management.

Arthroscopic Treatment of Fungous Arthritis of Knee Joint by Candida pelliculosa - A Case Report - (Candida pelliculosa에 의한 진균성 슬관절염의 관절경적 치료 - 증례 보고 -)

  • Kim, Hyung-Chun;Ahn, Su-Han;Kim, Kwang-Yeol;Hwang, Youn-Soo;Lee, Ji-Hoon;Lee, Dong-Eun
    • Journal of the Korean Arthroscopy Society
    • /
    • v.17 no.1
    • /
    • pp.79-83
    • /
    • 2013
  • Candida infection of knee joint is very rare. Diagnosis of Candida infection is difficult due to lack of obvious clinical symptoms. Candida albicans is the most common strain in Candida infection of knee joint, but Candida pelliculosa has been rarely reported. We report a case of Candida pelliculosa infection of knee after intra-articular steroid injection, which was treated successfully by repeated arthroscopic debridement and irrigations and arthroscopic implantation with antifungal agent-impregnated cement bead spacer.

  • PDF

Toxicity of Natural Uranium in Rats (천연우라늄의 독성에 관한 실험 연구)

  • Ryu, Yong-Wun;Lee, Jhin-Oh;Yun, Taik-Koo
    • Journal of Radiation Protection and Research
    • /
    • v.11 no.1
    • /
    • pp.44-50
    • /
    • 1986
  • Tissue distribution and blood chemistry of uranium in serum levels of BUN, Creatinine, SGPT and SGOT were determined in rats after the administration of uranylnitrate. Determination of uranium in organ was done by radio activation analysis. Radioactivity of $^{239}Np$ in lung was higher than in other tissues (e.g. liver, kidneys, spleen, tibia, testes, stomach and brain). Correlations between BUN and Creatinine were positively increased after the administration of 25 mg/kg uranylnitrate. The SGPT and SGOT activities showed weak correlation with the control group. However, activities of SGPT and SGOT after the administration of lmg/kg uranylnitrate showed high peak at 90 min interval. Uranium uptake by liver and kidneys increased at early period and decreased immediately to the control level. Lung who confirmed to be the critical organ on toxic effect by uranylnitrate.

  • PDF