• Title/Summary/Keyword: 임상 결과 예측

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Application of Low-Dose CT for Screening of Lung Disease (폐질환의 선별검사를 위한 저선량 전산화 단층촬영의 적용)

  • Lee, Won-Jeong;Choi, Byung-Soon;Park, Young-Sun;Seon, Jong-Ryul;Bae, Seok-Hwan
    • Journal of radiological science and technology
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    • v.32 no.2
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    • pp.129-140
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    • 2009
  • As CT has been increasingly used as an accurate screening tool for lung disease, radiation dose becomes an important issue for both radiographers and patients. Many researches have been done for a low-dose CT as a screening tool for early detection of asymptomatic lung diseases. From those studies, it has been reported that chest dose rate from the low-dose CT is considerably lower than from standard CT. The patient dose is determined by scanning parameters such as kVp, mAs, pitch, scan time and the radiation risk of lung in screening examination may not be negligible. Herein, we suggest that Low-dose CT is useful as a screening tool in routine clinical practice on the basis of published articles, but further study is necessary because Low-dose CT has poor sensitivity and specificity for screening early stage of lung cancer according to the results of the studies. This article is to provide a brief overview of the screening examinations by Low-dose CT.

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An Experience of Cox-maze III Procedure for Chronic Atrial Fibrillation (만성 심방세동에 대한 Cox-maze III 수술의 임상경험)

  • 김삼현;박이태;서필원;박성식;류재욱;최창휴;김명아;이명용;김영권
    • Journal of Chest Surgery
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    • v.31 no.7
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    • pp.668-673
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    • 1998
  • During the past several years, the maze operation has become the most effective method of treatment for chronic atrial fibrillation. When the maze procedure is done concomittantly with other cardiac operations, surgeons, in their initial experiences, may be concerned about the additional operative risks and uncertainty of the results. We performed the Cox-maze III procedure in six cases of chronic atrial fibrillation associated with mitral, mitral & aortic, or coronary arterial disease. Maze III procedure was done with open mitral commissurotomy(3 cases), mitral valve replacement(1 case), aortic and mitral valve replacement(1 case), and two-vessel coronary bypass graft(1 case). In spite of rather prolonged aortic cross clamp time, cardiac recovery was uneventful in all cases. No cases required reexploration for postoperative bleeding. All patients showed regular sinus rhythms immediate or between 2 and 20 days postoperateratively. Transient postoperative supraventricular arrhythmarias were easily controlled by various antiarrhythmic agents. In follow up evaluations, all cases showed regular sinus rhythm on ECG and the right and left atrial transport function was confirmed by Doppler echocardiography in all except one. Though our experience was limited in case number, the Cox-maze III procedure was effective in controlling the chronic atrial fibrillation without serious additional operative risks.

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The Role of Independent and Interdependent Self-Construals in Marital Satisfaction among Men and Women (기혼남녀의 자기관과 결혼만족의 관계 - 독립 및 상호의존적 자기관을 중심으로-)

  • Hyun, Kyoung-Ja
    • Korean Journal of Social Welfare
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    • v.56 no.4
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    • pp.239-268
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    • 2004
  • This study examined the role of self-construals in marital satisfaction among men and women, and explored how independent and interdependent self-construals contribute to or undermine marital satisfaction. Data were drawn from a self-administered questionnaire study in which 489 married people(aged 25-75) residing in Seoul participated. Path analyses were conducted using Structural Equation Modeling Program, and a goodness of fit of the proposed path model was evaluated. As expected, the positive impact of independent self-construal on marital satisfaction was mediated by self-esteem and clarity of communication, and that of interdependent self-construal on marital satisfaction was mediated by psychological stability and a sense of relational well-being. The direct effects of these two types of self-construal on marital satisfaction were opposite. As predicted, independent self-construal decreased marital satisfaction, whereas interdependent self-construal increased it. All of the direct and indirect effects of independent and interdependent self-construals on marital satisfaction were statistically significant, except the indirect effect of interdependent self-construal as mediated by psychological stability. The goodness of fit indexes of the path model indicated that the model was acceptable. However, the results of separate path analyses for men and women showed that some of the effects of self-construals on marital satisfaction differed by gender. Based on these results, implications for clinical social work practice were discussed.

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Detection Characteristics of Irradiated Aloe vera by the Analysis of PSL, TL and ESR (감마선 조사된 알로에 베라의 PSL, TL 및 ESR 검지 특성)

  • Kim Byeong-Keun;Lim Sang-Yong;Song Hyun-Pa;Yun Hye-Jeong;Kwon Joong-Ho;Kim Dong-Ho
    • Food Science and Preservation
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    • v.13 no.1
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    • pp.61-65
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    • 2006
  • Photostimulated luminescence (PSL), thermoluminescence(TL) and electron spin resonance (ESR) analyses were conducted to detect irradiation treatment of aloe vera powder, which was gamma-irradiated at 1, 3, 5 and 7 kGy. The non-irradiated aloe vera powder indicated below 700 of photon count in PSL, whereas, irradiated at 1 kGy and more, it showed more than 5,000 photon counts, indicating that it is feasible to detect the irradiation of aloe vera powder through PSL In the result of TL, from the minerals of the samples that were irradiated at more than 1 kGy, TL glow curve was able to be seen at around $150^{\circ}C$. As the quantity of irradiation goes up, the ratio of $TL_1\;and\;TL_2$ also increased in proportion to that of irradiation. In the result of ESR analysis, unspecific centeral ESR signal was could be seen. As the amount of irradiation on the samples increased to the level of $R^2=0.97$, the signal intensity also rose similarly. In conclusion, the PSL, TL and ESR exhibited the typical signals induced by irradiation treatment and were able to successfully detect all of the irradiated aloe vera powder. In addition, we found a positive correlation between the intensity of ESR and TL signals and irradiation doses.

Estimation of Potential Wood Supply by according to Geographical and Forest Management Conditions in Korea (지리 및 임업경영 여건을 고려한 유형별 목재공급 잠재량 추정)

  • Won, Hyun-Kyu;Jang, Kwang-Min;Kim, Youngh-Wan;Lee, Kyeong-Hak;Kim, Hyung-Ho
    • Journal of agriculture & life science
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    • v.45 no.3
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    • pp.35-41
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    • 2011
  • The objective of this study was to estimate domestic potential wood supply according to geographical and forest management conditions. In order to separate available wood supply area, analysis was conducted by separating natural, theoretical, geographical and technical supply area. Natural supply area was separated by extract stocked land from forest using digital stock map. Theoretical, geographical and technical supply area was separated by considering protection area, slope, streamside and road. Growing stock was calculated by using species and age-class of digital stock map. Potential wood supply was estimated by calculating growing stock of technical supply area. The results of growing stock of each supply area was shown that growing stock was from 244,150 to 596,248 thousand $m^3$. According to the results of this study, it was found that potential wood supply are likely to be over- or underestimated depending on the considered level of geographical and forest management conditions. Provincial potential wood supply was highly ranked in order of Gyeongbuk, jeonnam, Gyeongnam and Gangwon province.

The Effect of Leukoaraiosis on the Severity and Course of Delirium (백질변성이 섬망의 심각도 및 경과에 미치는 영향)

  • Choi, Won-Jung;Seok, Jeong-Ho;Oh, Seung-Taek;Chung, Tae-Sub;Kim, Jae-Jin
    • Korean Journal of Psychosomatic Medicine
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    • v.26 no.2
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    • pp.194-200
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    • 2018
  • Objectives : The significance of leukoaraiosis on brain magnetic resonance imaging (MRI) is uncertain, but it is often seen with vascular risk factors or in the context of cognitive impairment. We aimed to investigate the effect of leukoaraiosis on the severity and course of delirium. Methods : Periventricular hyperintensity and deep white matter hyperintensity on brain MRI were rated in 42 patients with delirium by semiquantative visual rating scale. Correlations between their grades and the scores of Korean version of Delirium Rating Scale-Revised-98 (K-DRS-R-98) were analyzed, and the interaction effects between the groups according to the levels of leukoaraiosis and two evaluation points were also analyzed. Results : The grade of deep white matter hyperintensity in the occipital lobe was positively correlated with the scores on the total, severity items, cognitive items, and non-cognitive items of K-DRS-R-98. The cognitive items scores of K-DRS-R-98 in the low grade group of periventricular hyperintensity showed significantly steeper decrease than the high grade group. Conclusions : A difference in severity or recovery speed of delirium according to the level of leukoaraiosis may result from disruption in brain functional connectivity. Our results have a clinical implication in that the severity and course of delirium can be possibly predicted using the level of leukoaraiosis.

An Investigation of the Correlation Between Renal Function Tests and Ultrasound Diagnosis based on Age and Gender in a Group with Normal Kidney Ultrasound Findings (신장 초음파 검사 결과가 정상인 그룹에서 연령과 성별에 따른 신장 기능검사와 초음파 진단의 상호 연관성 고찰)

  • Cheol-Min Jeon;Jong-Gil Kwak;Joo-Ah Lee
    • Journal of the Korean Society of Radiology
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    • v.18 no.5
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    • pp.411-417
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    • 2024
  • Renal ultrasound can detect kidney diseases by observing the size and shape of the kidneys, but its functional predictive value is relatively low. Kidney function can decrease by 20-30% without significant clinical changes or specific symptoms. This study aimed to confirm the limitations of renal ultrasound in functional aspects while acknowledging its usefulness in structural evaluation. It compared and analyzed the results of kidney function tests (serum creatinine, glomerular filtration rate, blood urea nitrogen, proteinuria, hematuria) according to age and gender in a normal group without structural abnormalities on renal ultrasound. In the comparison of kidney function tests by gender, differences were observed in BUN, Creatinine, GFR, and RBC, while no difference was found in Urine Protein, indicating functional differences between genders. Significant differences were observed in BUN and GFR across age groups, with GFR showing a decreasing trend with increasing age. Between genders, significant differences were found in BUN, creatinine, GFR, and RBC. Men had higher BUN and creatinine levels, while women had higher GFR. The prevalence of abnormalities in blood tests was 3.3%, and in urine tests was 6.1%. These limitations suggest that renal ultrasound alone may not be sufficient. It is essential to consider other diagnostic methods and conduct various tests in combination to more accurately evaluate kidney function and potentially detect problems early in asymptomatic adults.

Study about the clinical features and Pulmonary function Tst of Endobronchial Tuberculosis (기관지결핵의 임상상 및 폐기능검사에 관한 연구)

  • Chung, Hee-Soon;Lee, Jae-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.2
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    • pp.147-158
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    • 1996
  • Background : Endobronchial tuberculosis(ET) is known to affect frequently young female and serious complication like bronchial stenosis would occur if early diagnosis and treatment for ET is not performed immediately. But ET shows normal chest roentgenogram in about 10% of patients, and is often confused with bronchial asthma because ET presents clinical features like cough, dyspnea, wheezing in history and physical examination. The pulmonary function test(PFT) feature of ET is not well known, but when we consider the fact that ET is pathophysiologically different from bronchial asthma, if there is any feature of PFT in ET, and we know it, PFT will be very helpful for diagnosis and follow up of ET. Methods : We performed both PFT and bronchoscopy in 68 ET patients who visited Boramae hospital, and were confirmed as ET by bronchoscopic biopsy and were followed prospectively from November 1991 to March 1995. After history taking and physical examination, we performed chest roentgenogram, complete blood count, sputum AFB stain and culture, and also performed PFT before anti-tuberculosis chemotherapy. PFT was classified as restrictive, if only PVC was reduced below 80%, and obstructive, if only FEV1 was reduced below 75%. In the case of both FVC and FEV1 were reduced, PFT was classified as restrictive if FEY1/FVC was greater than 75%, and mixed if FEV1/FVC was reduced below 75%. We repeated the PFT and bronchoscopy for 68 ET patients who were proven by biopsy in the first month and sixth month after starting anti-tuberculosis chemotherapy, and studied the feature and change of PFT of the ET and the relation between PFT and the bronchoscopic finding, and obtained following results. Results: 1) Number of male patients was 12, and that of female patient was 56, and mean age was $35.4{\pm}17yr$.(17-74yr). Clinical symptom was in the order of cough(86.8%), dyspnea(63.2%), fever(17.6%) and hemoptysis (10.3%), and the wheezing and stridor were audible among the 40 patients(58.4%) in the physical examination. 2) Hemoglobin level was below 12g/dl among 25 patients (36.8%), and WBC level was above $10,000/mm^3$ among 9 patients(13.2%) and ESR was above 20 among 46 patients (67.6%) and AFB stain and culture were positive among 50 patients(73.5%). 3) The dominant roentgenographic finding of ET was fibronodular feature in 35 patients(51.5%), pneumonic feature in 14 patients (20.6%), collapse in 11 patients(16.2%), mass-like lesion in 3 patients(4.4%), cavitary lesion in 2 patients(2.9%), and normal in 3 patients(4.4%). 4) PFT feature at the time of diagnosis of ET was normal in 16 patients(23.5%), restrictive pattern in 32 patients (47%), obstructive in 4 patients(5.8%), and mixed in 14 patients(23.5%). So restrictive pattern was the dominate feature of ET. 5) The PFT feature was little correlated with the gross finding of bronchoscopy, but the change of PFT during treatment of ET showed relatively good correlation with the change of bronchoscopic finding. 6) FVC(2.30L vs. 2.61L) and FEV1(1.74L vs. 2.06L) increased significantly (p < 0.01), but FEV1/FVC(82% vs. 83%) and PEF(3.45L/sec vs. 3.95L/sec) did not change significantly after 1 month of treatment (p > 0.01), and there was no significant change among all parameters during first and sixth month of treatment(p > 0.01). Conclusion : PFT may be useful in the diagnosis and treatment follow up of ET but further study would be needed to confirm it.

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Clinical Experience of Three Dimensional Conformal Radiation Therapy for Non-Small Cell Lung Cancer (비소세포성 폐암에서 3차원 입체조형 방사선 치료 성적)

  • Choi Eun Kyung;Lee Byong Yong;Kang One Chul;Nho Young Ju;Chung Weon Kuu;Ahn Seung Do;Kim Jong Hoon;Chang Hyesook
    • Radiation Oncology Journal
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    • v.16 no.3
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    • pp.265-274
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    • 1998
  • Purpose : This prospective study has been conducted to assess the value of three dimensional conformal radiation therapy (3DCRT) for lung cancer and to determine its potential advantage over current treatment approaches. Specific aims of this study were to 1) find the most ideal 3DCRT technique 2) establish the maximum tolerance dose that can be delivered with 3DCRT and 3) identify patients at risk for development of radiation pneumonitis. Materials and Methods : Beginning in Nov. 1994, 95 patients with inoperable non-small cell lung cancer (stage I; 4, stage II; 1, stage IIIa; 14, stage IIIb; 76) were entered onto this 3D conformal trial Areas of known disease and elective nodal areas were initially treated to 45 Gy and then using 3DCRT technique 65 to 70 Gy of total dose were delivered to the gross disease. Sixty nine patients received 65 Gy of total dose and 26 received 70 Gy Seventy eight patients (82.1$\%$) also received concurrent MVP chemotherapy. 3DCRT plans were compared with 2D plans to assess the adequacy of dose delivery to target volume, dose volume histograms for normal tissue, and normal tissue complication Probabilities (NTCP). Results : Most of plans (78/95) were composed of non-coplanar multiple (4-8) fields. Coplanar segmented conformal therapy was used in 17 pateints, choosing the proper gantry angle which minimize normal lung exposure in each segment. 3DCRT gave the full dose to nearly 100$\%$ of the gross disease target volume in all patients. The mean NTCP for ipsilateral lung with 3DCRT (range; 0.17-0.43) was 68$\%$ of the mean NTCP with 2D treatment planning (range; 0.27-0.66). DVH analysis for heart showed that irradiated volume of heart could be significantly reduced by non-coplanar 3D approach especially in the case of left lower lobe lesion. Of 95 patients evaluable for response, 75 (79$\%$), showed major response including 25 (26$\%$) with complete responses and 50 (53$\%$) with partial responses. One and two rear overall survivals of stage III patients were 62.6$\%$ and 35.2$\%$ respectively. Twenty percent (19/95) of patients had pneumonitis; Eight patients had grade 1 pneumonitis and 11 other patients had grade 2. Comparison of the average of NTCP for lung showed a significant difference between patients with and without radiation pneumonitis. Average NTCP for Patients without complication was 62$\%$ of those with complications. Conclusions : This study showed that non-coplanar multiple fields (4-8) may be one of the ideal plans for 3DCRT for lung cancer. It also suggested that 3DCRT may provide superior delivery of high dose radiation with reduced risk to normal tissue and that NTCP can be used as a guideline for the dose escalation.

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Target Advertisement Service using a Viewer's Profile Reasoning (시청자 프로파일 추론 기법을 이용한 표적 광고 서비스)

  • Kim Munjo;Im Jeongyeon;Kang Sanggil;Kim Munchrul;Kang Kyungok
    • Journal of Broadcast Engineering
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    • v.10 no.1 s.26
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    • pp.43-56
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    • 2005
  • In the existing broadcasting environment, it is not easy to serve the bi-directional service between a broadcasting server and a TV audience. In the uni-directional broadcasting environments, almost TV programs are scheduled depending on the viewers' popular watching time, and the advertisement contents in these TV programs are mainly arranged by the popularity and the ages of the audience. The audiences make an effort to sort and select their favorite programs. However, the advertisement programs which support the TV program the audience want are not served to the appropriate audiences efficiently. This randomly provided advertisement contents can occur to the audiences' indifference and avoidance. In this paper, we propose the target advertisement service for the appropriate distribution of the advertisement contents. The proposed target advertisement service estimates the audience's profile without any issuing the private information and provides the target-advertised contents by using his/her estimated profile. For the experimental results, we used the real audiences' TV usage history such as the ages, fonder and time of the programs from AC Neilson Korea. And we show the accuracy of the proposed target advertisement service algorithm. NDS (Normalized Distance Sum) and the Vector correlation method, and implementation of our target advertisement service system.