• Title/Summary/Keyword: 임상적 특성

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Oxygen and Hydrogen Isotope Studies of Fluid-Rock Interaction of the Radons-Sancheong Anorthositic Rocks (하동-산청 회장암질암의 유체-암석 상호반응에 대한 산소와 수소 동위원소 연구)

  • Park Young-Rok;Ko Bokyun;Lee Kwang-Sik
    • The Journal of the Petrological Society of Korea
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    • v.13 no.4
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    • pp.224-237
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    • 2004
  • The anorthositic rocks of the study area are divided into the northern Sancheong and southern Hadong anorthositic rocks depending on the different distribution patterns and lithologies. In order to evaluate the characteristics of the hydrothermal systems developed in the study area, oxygen and hydrogen isotopic compositions of the anorthositic rocks were measured. Oxygen isotopic values of the plagioclase exhibit an interesting spatial distribution. Plagioclase collected from the Sancheong anorthositic rocks in the northern part tends to have a relatively restricted range of $\delta$$^{18/0}$ values between 7.3 and 8.8$\textperthousand$, which are heavier than 'normal' $\delta$$^{18/O}$ value (6-6.5$\textperthousand$) typical for plagioclase of the fresh mantle-derived anorthosite, whereas plagioclase from the southern part is characterized by a wide range of $\delta$$^{18/O}$ values between -4.4 and 8.2$\textperthousand$ and much lighter values than 'normal' value for plagioclase of the fresh mantle-derived anorthosite. Plagioclase from the middle part has $\delta$$^{18/O}$ values heavier than the plagioclase from the southern part, but lighter than that from the northern part. The spatial distribution of $\delta$$^{18/O}$ values suggests that the decoupled hydrothermal flow systems might have been developed in the study area. Meteoric water dominated in the hydrothermal flow systems developed in the southern area, whereas magmatic fluid dominated in the northern area. The relationship between water content and hydrogen isotopic composition of anorthosites shows a positive correlation. The positive correlation indicates that fluids exsolved from magma during magmatic differentiation caused deuteric alteration of anorthositic rocks involving replacement of pyroxenes to amphiboles. After the deuteric alteration, hydrothermal system developed by meteoric water dominated the southern area, and erased record of the hydrothermal system developed by magmatic fluid at earlier stage. However, the development of meteoric hydrothermal system has been limited in the southern area only, and could not affect the Sancheong anorthositic rocks in the northern area. The abundant occurrences of secondary alteration minerals such as sericite, calcite, and chlorite in the southern Hadong anorthosite relative to the northern Sancheong anorthositc seem to be related to the overlapping of two distinct hydrothermal systems in the southern area.

A Comparative Study of Effect of Secondary Anti-tuberculosis Drugs in the Retreatment of Pulmonary Tuberculosis (폐결핵 재치료에서 이차항결핵제 복합처방의 효과에 관한 비교 연구)

  • Ha, Hyun-Cheol;Kwon, Eun-Soo;Choi, In-Hwan;Hwang, Su-Hee;Park, Seung-Kyu;Song, Sun-Dae
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.6
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    • pp.1154-1166
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    • 1998
  • Background : In the management of patients whose primary chemotherapy has failed, careful assessment is essential. It is important to find out as accurate a chemotherapy history as possible. Preferably it should contain the drugs which has never used before. The purpose of present study is establishment of retreatment regimen for pulmonary tuberculosis. The present report concerns the results of retreatment of pulmonary tuberculosis patients treated at National Masan Tuberculosis Hospital. Methods : Retrospective cohort study was made of 104 drug-resistant pulmonary tuberculosis patients who were treated by five regimens between Jan. 1994 and Nov. 1996. All the patients taken medicine for second anti-tuberculosis regimens for the first time. We separated the patients by three groups(Group I ; OFX+PTA+CS+PAS+Aminoglycoside, Group II : PZA+PTA+CS+PAS+Aminoglycoside, Group III : PZA+OFX+PTA+PAS+Aminoglycoside). Results : The age distribution was most frequent in fourth decade(36patients, 34.6%) and the mean age was 42.6 year. The sex distribution was more frequent in the males(81 patients, 85.7%). There was 31 patients(29.8%) with combined diseaes, 18 patients with complication and 24 patients(27.9%) with family history. Primary chemotherapy regimens were HERZ(S or K) in 48 patients (46.2%), HER(S or K) in 41 patients(39.4%) and others in 15 patients(14.4%). Result of drug sensitivity test showed that the resistance to INH and RFP is in 68 patients(65.4%), RFP is 12 patients(11.5%), INH is in 3 patients(2.9%) and all sensitive to INH and RFP is 3 patients(2.9%). The clinical symptoms on admission were coughing(89.4%), sputum(69.2%), dyspnea on exertion(37.5%), weight loss(33.7%) blood tinged sputum(15.4%) and others. The extent of disease on the radiograph was far-advanced in 73 patients(70.2%), moderate in 28 patients(26.9%) and minimal in 3 patients(2.9%). The side effects for drugs were gastrointestinal troubles in 31 patients(29.8%), arthralgia in 22 patients(21.2%), skin rash in 12 patients(11.5%) and others. The negative conversion rate on sputum AFB smear was 85.6%(87.5% in Group I, 80.0% in Group II and 90.5% in Group III). The average negative conversion time on sputum was 4 month(4.0 month in Group I, 4.6 month in Group II and 3.0 month in Group III). Conclusion : In the retreatment of pulmonary tuberculosis, ofloxacin is useful drug for the patients who are not available to use PZA and combination of PZA and OFX can be use effectively substituting for CS.

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Clinical Characteristics in Panic Disorder Patients in Emergency Department (공황발작으로 응급실에 내원한 공황장애 환자들의 임상 특징)

  • Lee, Chang-Ju;Nam, Beom-Woo;Sohn, In-Ki
    • Korean Journal of Psychosomatic Medicine
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    • v.29 no.1
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    • pp.26-33
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    • 2021
  • Objectives : This study was designed to investigate datas related to panic attack and treatment in emergency room of panic disorder patients who visited emergency room for panic attack. Methods : A retrospective analysis of medical records was conducted on 92 patients with panic disorder who visited Chungju Konkuk university hospital emergency department due to panic attack and had bodily symptoms from 1st January 2010 to 31th December 2019. In addition to demographic characteristics and comorbid disorders, triggering stressors and alcohol consumption were corrected as pre-panic attack datas, bodily symptoms at the time of panic attack were corrected as datas during attack, electrocardiogram trial, consultation with psychiatrist, admission and information of used psychotropic drugs were corrected as post-attack data. Depending on size of data, Chi-square test or Fisher's exact test was used. Collected data was analyzed using R 4.03. Results : Cardiovascular disease was accompanied by 5.4% and depressive disorder was the most common coexisting mental disorder. Among triggering stressors, economic problem/work-related stress was significantly higher in men than women (𝛘2=4.322, p<0.005). The most common physical symptom during attack was circulatory (65.2%), followed by respiratory (57.6%), numbness-paralysis (33.7%), dizziness (19.6%), gastro-intestinal (14.1%) and autonomic symptom (12.0%). Electrocardiogram was taken at higher rate when patients complained circulatory symptom (𝛘2=8.46, p<0.005). The psychotropic drug most commonly used in emergency room was lorazepam, used in 92.1%. Conclusions : The most common bodily symptom during panic attack was circulatory symptom and the most common triggering stressor in men was economic problem/work-related stress. The most commonly used psychotropic for panic attack was lorazepam.

Comparison of the Bone Union Rates Using a Local Autobone and Bone Graft Substitute Mixed Graft in Lumbar Posterolateral Fusion (요추부 후측방 유합술 시 국소 자가골 및 골 이식 대체재 혼합 이식에 의한 골유합률의 비교)

  • Ko, Young-Chul;Hong, Seong-Hwak;Park, Man-Jun;Huh, Jung-Wook;Park, Joon-Hyung;Lee, Woo-Myung
    • Journal of the Korean Orthopaedic Association
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    • v.55 no.2
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    • pp.169-177
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    • 2020
  • Purpose: To assess the effectiveness of mixed grafts in lumbar posterolateral fusion (PLF) by comparing the bone union rates of an autobone with a bone substitute mixed graft. Materials and Methods: The patients were followed-up for at least two years after PLF and divided into four groups according to the mixed graft retrospectively. Group I was 48 cases using a femoral head allobone. Group II was 38 cases using β-tricalcium phosphate. Group III was 92 cases using biphasic calcium phosphate. Group IV was 38 cases using biphasic calcium phosphate and autologous bone marrow. Union was evaluated by the work up simple radiographs after two years from PLF. Union was defined if the radiographs demonstrated a bilateral continuity in the fusion mass between the cephalad and caudal transverse processes with less than 2° of angular motion and no translation between the vertebrae at the level of fusion on the lateral flexion-extension radiographs. Results: According to simple radiographs after two years from PLF, the rate of union was highest in Group IV using local autobone, biphasic calcium phosphate and autologous bone marrow mixed graft. Conclusion: Biphasic calcium phosphate is an osteoconductive bone substitute that increases the bio-absorbability and mechanical strength. Autologous bone marrow has osteoinductive and osteogenic properties. These features can increase the rate of bone union. Therefore, a local autobone, biphasic calcium phosphate and autologous bone marrow mixed graft can be considered an effective bone graft substitute for lumbar PLF instead of an autobone graft.

Evaluation of Physical Properties and Material Characterization for Structural Frame at the Stained Glass Windows to Gongju Jeil Church of the Registered Cultural Heritage in Korea (국가등록문화재 공주제일교회 스테인드글라스 구조재의 재질특성과 물성 평가)

  • Bo Young Park;Hye Ri Yang;Chan Hee Lee
    • Economic and Environmental Geology
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    • v.56 no.1
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    • pp.103-114
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    • 2023
  • The Christian Museum of Gongju Jeil Church was first built in 1931 and was largely damaged during the Korean War, but the walls and chimneys have been preserved. This building has a high architectural values in that the chapel was reconstructed in 1956, and maintains its original form through repair of damaged parts rather than new construction. The stained glass windows were as installed in 1979 and has a great significance in the Dalle de Verre method using lump glass. However, some of the stained glass damaged partially, such as various cracks and splits, and vertical and horizontal cracks in the joint fillers of supporting the colored glass. As the structural materials of the stained glass window, an iron frame and cement mortar filled with it were used, and corrosion of iron, cracking of mortar and granular decomposition appear partially due to weathering. In the joint fillers, the content of Ca and S is very high, indicating that gypsum were used as admixtures, and the gypsums grow in a rhombohedral and forms a bundle, which is investigated to have undergone recrystallization. As a result of modeling the ultrasonic velocity at the joint fillers, the left and right windows at the entrance show relatively weak in the range of 800 to 1,600m/s, and the lower right corner of the altar window and the upper left corner of the center window were also 1,000 to 1,800m/s, showing relatively low physical properties. And gypsums produced during the neutralization of lime mortar were detected in the joint fillers and contaminants on the surface. Such salts may cause damage to the joint material due to freezing and thawing, so appropriate preventive conservation is required. Also, since various damage types are complexly appearing in stained glass window and joint filler, customized conservation treatment should be reviewed through clinical tests.

The Development and Characteristics of Diluvial Soils on the Catena (홍적층(洪積層) Catena에서 토양(土壤)의 발달(發達)과 특성(特性))

  • Rim, Sang-Kyu;Choi, Jyung
    • Korean Journal of Soil Science and Fertilizer
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    • v.17 no.3
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    • pp.200-206
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    • 1984
  • This study was conducted to examine the morphological, physical and chemical characteristics of the Bancheon, Gopyeong, Hwadong and Deogpyeong series derived from diluvium in Korea. The results were as follows. 1. The sequence of the Bancheon, Gopyeong, Hwadong and Deogpyeong series consists of the soil catena. Thus, the Bancheon and Gopyeong series are weil drained, the Hwadong and Deogpyeong series moderately well drained due to the influence of topography and irrigation water. 2. The surface soils of the Bancheon and Gopyeong series are yellowish red, dark yellowish brown fine silty texture and the subsoils are yellowish red, red and strong brown fine clayey with moderate to strong angular blocky or subangular blocky structure with clayey cutans on the structural face. The surface soils of the Hwadong and Deogpyeong series are dark grayish brown, grayish brown fine silty texture and the subsoils are strong brown, light olive brown and brownish yellow fine silty or fine clayey with moderate to strong prismatic, angular blocky or subangular blocky structure with clayey cutans on the structural face. The consistences of all the subsoil horizons are extremely compact and hard, whereas sticky and plastic when wet. 3. The lower the topography, the higher the silt/clay ratio, soil reaction, organic matter, available water and phosphate content but the higher the topography, the higher the active iron content. 4. These soils are classified as Hapludalfs by Soil Taxonomy in U.S.D.A. 5. These soils must be applied with much lime, phosphate and compost to improve the soil fertility.

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Usability of Multiple Confocal SPECT SYSTEM in the Myocardial Perfusion SPECT Using $^{99m}Tc$ ($^{99m}Tc$을 이용한 심근 관류 SPECT에서 Multiple Confocal SPECT System의 유용성)

  • Shin, Chae-Ho;Pyo, Sung-Jai;Kim, Bong-Su;Cho, Yong-Gyi;Jo, Jin-Woo;Kim, Chang-Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.2
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    • pp.65-71
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    • 2011
  • Purpose: The recently adopted multiple confocal SPECT SYSTEM (hereinafter called IQ SPECT$^{TM}$) has a high difference from the conventional myocardial perfusion SPECT in the collimator form, image capture method, and image reconstruction method. This study was conducted to compare this novice equipment with the conventional one to design a protocol meeting the IQ SPECT, and also determine the characteristics and usefulness of IQ SPECT. Materials and Methods: 1. For the objects of LEHR (Low energy high resolution) collimator and Multiple confocal collimator, $^{99m}Tc$ 37MBq was put in the acrylic dish then each sensitivity ($cpm/{\mu}Ci$) was measured at the distance of 5 cm, 10 cm, 20 cm, 30 cm, and 40 cm respectively. 2. Based on the sensitivity measure results, IQ SPECT Protocol was designed according to the conventional general myocardial SPECT, then respectively 278 kBq/mL, 7.4 kBq/mL, and 48 kBq/mL of $^{99m}Tc$ were injected into the myocardial and soft tissues and liver site by using the anthropomorphic torso phantom then the myocardial perfusion SPECT was run. 3. For the comparison of FWHMs (Full Width at Half Maximum) resulted from the image reconstruction of LEHR collimator, the FWHMs (mm) were measured with only algorithms changed, in the case of the FBP (Filtered Back projection) method- a reconstruction method of conventional myocardial perfusion SPECT, and the 3D OSEM (Ordered subsets expectation maximization) method of IQ SPECT, by using $^{99m}Tc$ Line source. Results: 1. The values of IQ SPECT collimator sensitivity ($cpm/{\mu}Ci$) were 302, 382, 655, 816, 1178, and those of LEHR collimator were measured as 204, 204, 202, 201, 198, both at the distance of 5 cm, 10 cm, 20 cm, 30 cm, and 40 cm respectively. It was found the difference of sensitivity increases up to 4 times at the distance of 30 cm in the cases of IQ SPECT and LEHR. 2. The myocardial perfusion SPECT Protocol was designed according to the geometric characteristics of IQ SPECT based on the sensitivity results, then the phantom test for the aforesaid protocol was conducted. As a result, it was found the examination time can be reduced 1/4 compared to the past. 3. In the comparison of FWHMs according to the reconstructed algorithm in the FBP method and 3D OSEM method followed after the SEPCT test using a LEHR collimator, the result was obtained that FWHM rose around twice in the 3D OSEM method. Conclusion : The IQ SPECT uses the Multiple confocal collimator for the myocardial perfusion SPECT to enhance the sensitivity and also reduces examination time and contributes to improvement of visual screen quality through the myocardial-specific geometric image capture method and image reconstruction method. Due to such benefits, it is expected patients will receive more comfortable and more accurate examinations and it is considered a further study is required using additional clinical materials.

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Effects of heat treatment on the load-deflection properties of nickel-titanium wire (니켈-티타늄 와이어의 열처리에 따른 부하-변위 특성 변화)

  • Chang, Soo-Ho;Kim, Kwang-Won;Lim, Sung-Hoon
    • The korean journal of orthodontics
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    • v.36 no.5
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    • pp.349-359
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    • 2006
  • Objective: Nickel-titanium alloy wire possesses excellent spring-back properties, shape memory and super-elasticity. In order to adapt this wire to clinical use, it is necessary to bend as well as to control its super-elastic force. The purpose of this study is to evaluate the effects of heat treatment on the load-deflection properties and transitional temperature range (TTR) of nickel-titanium wires. Methods: Nickel-titanium wires of different diameters ($0.016"\;{\times}\;0.022"$, $0.018"\;{\times}\;0.025"$ and $0.0215"\;{\times}\;0.028"$) were used. The samples were divided into 4 groups as follows: group 4, posterior segment of archwire (24 mm) without heat treatment; group 2, posterior segment of archwire (24 mm) with heat treatment only; group 3, anterior segment with bending and heat treatment; group 4, anterior segment with bending and 1 sec over heat treatment. Three point bending test was used to evaluate the change in load-deflection curve and obtained DSC (different scanning calorimetry) to check changes in $A_f$ temperature. Results: In the three point bending test, nickel-titanium wires with heat treatment only had higher load-deflection curve and loading and unloading plateau than nickel-titanium wires without heat treatment. Nickel-titanium wires with heat treatment had lower Af temperature than nickel-titanium wires without heat treatment. Nickel-titanium wires with heat treatment and bending had higher load-deflection curve than nickel- titanium wires with heat treatment and nickel-titanium wires without heat treatment. Nickel-titanium with heat treatment of over 1 sec and bending had the highest load-deflection curve. Nickel-titanium wires with heat treatment and bending had lower Af temperature, Nickel-titanium wires with heat treatment of over Af sec and bending had the lowest Af temperature. Conclusion: From the results of this study, it can be stated that heat treatment for bending of Nickel-titanium wires does not deprive the superelastic property but can cause increased force magnitude due to a higher load-deflection curve.

Recognition and Attitudes on DNR of College Students (Focused on Comparison between Nursing and Non-Health Department College Students) (DNR에 대한 대학생들의 인식 및 태도(간호대학생과 비 보건계열대학생 비교를 중심으로))

  • Kim, Sung-Mi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.12
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    • pp.4907-4921
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    • 2010
  • The object of this descriptive survey research was to provide basic information source for building objective standards of DNR (Do Not Resuscitate) that can be clinically applied, by analyzing college students' awareness and attitude toward DNR. The participants of the study were 1,267 students from one college of Daegu, South Korea. The structured survey questionnaire was used for data collection, and the survey was conducted from 1-31 July, 2010. The error and percentage was estimated by SPSS 17.0 program, and analyzed with $x^2$-test. As a result of comparing the nursing students' and non-health care major students' awareness and attitude toward DNR, the significant differences were found in the necessity of DNR, reason for supporting DNR, reason for opposing DNR, and DNR decision-maker, among the awareness dimension; among the attitude dimension, significant differences were found in implication of family DNR and self-DNR. Comparing the nursing students' and non-health care major students' awareness toward DNR related information provision, researchers have found significant differences in the necessity of giving information on DNR, timing of the DNR information provision, result of the DNR-related information provision, and guidelines for the DNR information provision. In terms of the difference in DNR's necessity recognition by the demographic information, the significant differences existed based on the religion and the history of blood donation; in terms of the differences in attitude toward DNR decision-maker, the differences were found on the religion and the number of siblings. For the attitude toward family member's DNR, the significant differences existed for the sex, age, economic status, religion, the number of siblings, the history of familial illness and death, and experience of blood donation; the attitude toward the DNR for the self was significantly differed by the sex, economic status, the number of siblings, and the history of familial illness and death. To establish the standards for DNR based on the study, we suggest more well-designed future studies.

Dosimetric Characteristics on Penumbra Regions of the Multileaf Collimator as Compared with the Lead Alloy Block (다엽 콜리메이터(Multileaf Collimator)와 합금납 차폐물(Lead Alloy Block)의 반 그림자영역의 선량 분포상의 특성 비교)

  • Lee Sang Wook;Oh Young Tack;Kim Woo Cheol;Keum Ki Chang;Yoon Seong Ick;Kim Hyun Soo;Park Won;Chu Seong Sil;Kim Gwi Eon
    • Radiation Oncology Journal
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    • v.13 no.4
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    • pp.391-396
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    • 1995
  • Purpose : The Conformal Radiation Therapy has bee widely used under favour of development of computer technologies. The delivery of a large number of static radiation fields are being necessary for the conformal irradiation. In this paper we investigate dosimetric characteristics on penumbra regions of a multileaf collimator(MLC), and compare to those of lead alloy block for the optimal use of the system in 3-D conformal radiotherapy. Materials and Methods : The measurement of penumbra by MLC or lead alloy block was performed with 6 or 10 MV X-rays. The film was positioned at a dmax depth and 10 cm depth, and its optical density was determined using a scanning videodensitometer. The effective penumbra, the distance from $80{\%}$ to $20{\%}$ isodose lines and $90{\%}$ to $10{\%}$ were analyzed as a function of the angle between the direction of leaf motion and the edge defined by leaves. Results : Increasing MLC angle ($0-75^{\circ}$) was observed with increasing the penumbra widths and the scalloping effect. There was no definite differences of penumbra width from $80{\%}$ to $20{\%}$ isodose lines, while being the small increase of penumbra width from $90{\%}$ to $10{\%}$ isodose line varing the depth and energy. The effective penumbra width of lead alloy block are agree resonably with those of MLC within 4.8mm. Conclusion : The comparative qualitative study of the penumbra between MLC and lead alloy block demonstrate the clinical acceptability and suitability of the multileaf collimator for 3-D conformal radiotherapy.

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