• 대한임상약리학회:학술대회논문집
• /
• 1994.12a
• /
• pp.15-15
• /
• 1994

• 대한임상약리학회:학술대회논문집
• /
• 1998.12a
• /
• pp.58-58
• /
• 1998

• Communications for Statistical Applications and Methods
• /
• v.2 no.1
• /
• pp.229-247
• /
• 1995

신뢰할만한 임상시험연구결과를 얻기 위해서는 통계학자가 임상시험연구의 준비단계에서부터 실험계획 및 연구의 운용, 분석은 물론 결과의 보고에 이르기까지 총체적으로 관여해야 한다. 의학전문가들과의 원활한 공동연구를 위해서는 통계학자들이 의학분야에서의 용어나 관례, 임상시험이 이루어지는 절차등에 대한 명확한 이해가 필요하게 된다. 이 논문에서는 임상시험에서 진행되는 제반문제에 대해 통계학자가 숙지해야 할 사항들에 대해 논의 하였다.

• Proceedings of the Korea Contents Association Conference
• /
• 2014.11a
• /
• pp.299-300
• /
• 2014

생명과학분야에서는 생명현상을 이해하기 위해 신호 전달 네트워크에 대한 연구가 진행되고 있다. 하지만 신호전달 네트워크와 임상 정보를 결합하여 질병관점에서 신호 전달 네트워크를 통합하고 결합하는 관점의 연구가 부족하다. 따라서 본 논문에서는 빅데이터 기술을 활용하여 임상 및 신호전달 정보를 연계 분석할 수 있는 시스템을 구축하고자 빅데이터 분석을 위한 임상 및 바이오 정보 통합 데이터베이스를 설계한다. 설계한 임상 및 바이오 정보 통합 데이터베이스는 빅데이터 분석 기술을 적용한 확장 분석 기법 및 통합 분석 시스템 개발에 활용할 수 있다.

• Journal of Digital Convergence
• /
• v.18 no.9
• /
• pp.433-440
• /
• 2020

The purpose of this study is to analyze the research trend by conducting a systematic review of domestic research on clinical fieldwork in occupational therapy. From 2000 to 2019, papers registered in the Google Scholar, RISS, KISS, and National Library of Korea databases were searched. The search term was "Occupational Therapy" AND "Clinical Fieldwork", and a total of 8 studies were finally selected. As a result of analyzing the research trend, the most frequently used data collection method were surveys 6 studies(75.0%), and the most frequent subject were occupational therapy students was 6 studies(75.0%). The most frequent main theme was satisfaction of clinical fieldwork 4 studies(50.0%). In the future, it was confirmed that quantitative and qualitative growth of clinical research related to occupational therapy in Korea is needed.

• Journal of the Korean Data and Information Science Society
• /
• v.26 no.6
• /
• pp.1317-1325
• /
• 2015

There are two types of clinical research to figure out risk factor for disease using collected data. One is prospective study to approach the subjects from the present time and the other is retrospective study to find the risk factor using the subject's information in the past. Both approached and study design are different but the purpose of the two studies is to identify a significant difference between two groups and to find out what the variables to influence groups. Especially when comparing the two groups in clinical research, we have to look at the difference between the impact clinical variables by group while controlling the influence of the baseline characteristics variables such as age and sex. However, in the retrospective study, the difference of baseline characteristic variables can occur more frequently because the past records did not randomly assign subjects into two groups. In clinical data analysis use covariates to solve this problem. Typically, the analysis method using the analysis of covariance of variance, adjusted model, and propensity score matching method. This study is introduce the way of equality adjustment between groups data analysis using covariates in retrospective clinical studies and apply it to the recurrence of gastric cancer data.

• The Journal of the Convergence on Culture Technology
• /
• v.8 no.1
• /
• pp.417-425
• /
• 2022

This study is to understand the relationship between self-leadership, clinical competence, and clinical practice satisfaction of nursing students, and to investigate the effect of self-leadership and clinical competence on clinical practice satisfaction. Data collection was conducted from May 1 to May 16, 2019, and 186 questionnaires were used for analysis and analyzed through SPSS/WIN 28.0. The average of the participants's self-leadership was 3.44 points, the average of clinical competence was 3.82 points, and the average of clinical practice satisfaction was 3.69 points. Satisfaction with clinical practice was found to have a positive correlation with self-leadership(r=.221, p=.002) and clinical competence(r=.262, p<.001), and self-leadership and clinical performance(r=.050, p=.494) showed no correlation. The variables affecting clinical practice satisfaction were self-leadership(β=.251, p<.001) and clinical competence(β=.208, p=.003), and the explanatory power of these variables was 10.4%. Therefore, in order to increase the satisfaction of nursing students in clinical practice, it is necessary to develop a program that can improve self-leadership and clinical competence.

• Korean Journal of Clinical Laboratory Science
• /
• v.55 no.4
• /
• pp.244-252
• /
• 2023

The timeliness and accuracy of test results are crucial factors for clinicians to decide and promptly administer effective and targeted antimicrobial therapy, especially in life-threatening infections or when vital organs and functions, such as sight, are at risk. Further research is needed to refine and optimize matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)-based assays to obtain accurate and reliable results in the shortest time possible. MALDI-TOF MS-based bacterial identification focuses primarily on techniques for isolating and purifying pathogens from clinical samples, the expansion of spectral libraries, and the upgrading of software. As technology advances, many MALDI-based microbial identification databases and systems have been licensed and put into clinical use. Nevertheless, it is still necessary to develop MALDI-TOF MS-based antimicrobial-resistance analysis for comprehensive clinical microbiology characterization. The important applications of MALDI-TOF MS in clinical research include specific application categories, common analytes, main methods, limitations, and solutions. In order to utilize clinical microbiology laboratories, it is essential to secure expertise through education and training of clinical laboratory scientists, and database construction and experience must be maximized. In the future, MALDI-TOF mass spectrometry is expected to be applied in various fields through the use of more powerful databases.

• Journal of the Korean Data and Information Science Society
• /
• v.23 no.4
• /
• pp.643-648
• /
• 2012

There are lots of analysis to determine the relation between dependent variable and explanatory variables. Often the regression analysis is used to do this, and we can analyze the how much the explanatory variable can be related with dependent variable and how much the regression model can explain the data. But the validation check of regression model is usually determined by coefficient of determination. We should check the validation of regression coefficient with different methods. This paper introduces the method for validation check the regression coefficient using the jackknife regression and bootstrap regression in clinical data.

• Journal of Digital Convergence
• /
• v.17 no.12
• /
• pp.353-365
• /
• 2019

This study examined satisfaction with clinical training according to school system and school-related characteristics and analyzed the effect of satisfaction by clinical training task on the overall satisfaction with clinical training. Participants were convenience sampled from students of K University in Gangwon-do (n=279) and K University in Gyeonggi-do (n=154) who have undergone clinical training. The overall satisfaction with clinical training in dental hygiene students differed according to the school system, school-related characteristics, satisfaction by clinical training topic, and satisfaction by clinical training task. Satisfaction by clinical training task had an effect on overall satisfaction with clinical training. Thus, substantial effort, such as ensuring appropriate contents and methods of training.