• Journal of Life Science
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• v.24 no.11
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• pp.1180-1186
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• 2014

Autophagy, the lysosomal degradation pathway, is an intracellular recycling system that is necessary for the metabolic benefits of exercise and for producing lasting beneficial effects of exercise in various diseases. However, the most recent studies have only examined the effect of a single bout of exercise or resistance exercise on autophagic responses. To determine the differential effects of acute and chronic exercise on the expression of autophagy-related genes in D. melanogaster, white-eyed mutant D. melanogaster were assigned randomly to four groups: control, acute exercise, 2 hr chronic exercise, and 3 hr chronic exercise. The flies were exercised using a mechanized platform known as the Power Tower. Our results revealed that a single bout of exercise resulted in increased mRNA levels of the Atg8a gene (~20%, p<0.05). However, Atg1 and Atg6 mRNA expression were not induced by acute exercise. Transcript levels of Atg6 (~29%, p<0.05) related to the nucleation of autophagosomes were significantly induced by 2 hr of chronic exercise. However, this chronic exercise was not enough to increase Atg1 and Atg8a mRNA expression. On the other hand, 3 hr of exercise for 7 days significantly increased Atg1, Atg6, and Atg8a gene expression-about 57%, 37%, and 71%, respectively (p<0.05). These results suggest that a single bout of exercise is not enough to induce full activation of selected autophagy-related genes in D. melanogaster. Our results demonstrated that chronic regular exercise induced autophagy-related gene expression, suggesting that chronic regular exercise training might be required to activate autophagic responses important for producing beneficial effects of exercise in various diseases.

• Journal of Life Science
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• v.21 no.9
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• pp.1259-1265
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• 2011

The purpose of this study was to determine whether a single bout of aerobic exercise affects the expression level of toll-like receptor4 (TLR4), IL-6, TNF-${\alpha}$, and suppressor of cytokine signaling-3 (SOCS-3) expression in rat hindlimb muscles depending on fiber types. To accomplish this, thirteen 7-wk Balb/c male mice were randomly assigned to an experimental group or a control group. The exercise protocol consisted of a single bout of treadmill exercise (inclination $10^{\circ}$, speed 17 cm/sec 10 min, 33 cm/sec 10 min, 50 cm/sec) and the animals were killed 24 hr after the exhaustion protocol. The level of TLR4, IL-6, TNF-${\alpha}$, and SOCS-3 mRNA expression was measured by quantitative real-time PCR in soleus and plantaris muscles. A single bout of aerobic treadmill exercise increased TLR4 mRNA expression in the soleus muscle (p<0.05), whereas plantaris TLR4 mRNA expression did not change. Additionally, acute exercise led to a significant increase in IL-6, TNF-${\alpha}$, and SOCS-33 mRNA in the soleus muscle, while transcripts of these genes were not affected by exercise in the plantaris muscle. In conclusion, expression level of several immune-related genes such as TLR4, cytokines, and SOCS-3 is regulated by acute exercise in a fiber type specific manner.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1259-1267
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• 2023

The purpose of this study was to investigate the effects of a acute ankle mobility exercise (AE) program on the range of motion and pain levels associated with chronic ankle instability (CAI). Twenty adult women with an average score of 24 or less on both sides in the ankle instability questionnaire were selected and divided into two groups: the Ankle Mobility Exercise Program group (AE, n=10) and the control group (CON, n=10). The AE treatment involved a one-time, 20-minute exercise session for each ankle, conducted separately on the left and right ankles, to examine the response to a acute exercise. Measures of ankle instability, pain, and ankle range of motion were evaluated before and after the treatment. In the AE group, which underwent the AE program, a significant decrease in pain was observed post-AE compared to pre-AE (p<.01). In addition, an increase in dorsiflexion was observed in the AE group post-AE compared to pre-AE following the AE program(p<.05). These results suggest that a acute AE program can effectively alleviate some aspects of ankle instability by improving ankle pain and range of motion in adult women with chronic ankle instability (CAI).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.140-148
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• 2017

The purpose of this study was to examine the effects of acute aerobic exercise at different intensities on the blood pressure, blood lipids and fibrinolytic markers in pre-hypertension college-aged males. Six subjects performed an acute running exercise at three different intensities(low intensity(LI): 50-60% heart rate reserve(HRR), moderate intensity(MI): 60-70%HRR, and high intensity(HI): 70-80%HRR). The blood pressure(systolic(SBP) and diastolic blood pressure(DBP), blood lipids(total cholesterol(TC) and high-density lipoprotein cholesterol(HDL-C)) and fibrinolytic markers(tissue plasminogen activator(tPA) and plasminogen activator inhibitor-1(PAI-1)) were determined before(PRE), immediately after(POST) and 60minutes after the exercise(60 POST). Results: the SBP in the LI group was significantly increased at POST(p=0.013). The ES levels for the SBP in the MI and HI groups were reduced (-1.33 and -1.23, respectively), though the differences were not significant. The HDL in the MI(p=0.003) and HI(p=0.002) groups were significantly increased at 60 POST. Also, the tPA in the MI(p=0.021) and HI(p=0.042) groups were significantly increased at POST.

• Product Safety
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• s.64
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• pp.56-58
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• 1998

과거 정부의 일회성 캠페인에 전국민 차원에 그쳤던 에너지 절약운동이 지금은 국가 경제회생을 위한 관심과 실천사항으로 자리잡아가고 있다. 정부의 에너지 절약운동과 에너지 가격상승에 따른 소비자들의 수요증가로 에너지 절약형 상품이 부상하고 있다.

• Journal of Life Science
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• v.22 no.4
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• pp.532-537
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• 2012

We investigated the effect of smoking on cardiovascular responses during acute dynamic exercise. Eleven college students who had been smoking (duration of smoking: $7.45{\pm}0.90$ years; number of cigarettes per day: $17.72{\pm}1.22$) participated in this study. All subjects completed a graded exercise testing to determine the relative exercise intensity. The cardiovascular responses were measured at rest, and during mild and moderate exercise immediately, 24, and 48 hours after smoking. The same procedures were repeated during 24-h smoking withdrawal. All subjects were continuously instrumented to measure systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV), cardiac output (CO), and total vascular conductance (TVC) at rest and during exercise. The results showed that compared to the nicotine abstention, SBP, DBP, MAP, and HR were significantly higher at 24 and 48 hours after smoking ($p$<0.05), and CO was significantly higher at rest and during moderate exercise ($p$<0.05). There were no differences in SV and TVC before and after smoking. Thus, the results suggest that smoking is associated with an exaggerated sympathetic nerve activity during dynamic exercise. Consequently, smoking cessation may help reduce cardiac events, such as stroke and heart attack, during exercise.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.10
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• pp.3820-3825
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• 2010

The purpose of this study was to identify the effects of acute exercise on antioxidative enzymes in noramal and obese men. The written informed consent was obtained from 16 participants of eight normally healthy persons and eight obesity ones. The baseline level of obesity was determined at 25 % of the body fat. Any subjects had no experiences in participating in exercise and did not take vitamin or mineral supplement. Blood was sampled at five minutes before exercise, at exhaustion, and after 30 minutes of recovery. All statistical analyses and description methods were computed by SPSS window 14.0. Analysis of Covariance(ANCOVA) was performed to know the differences in values between pre- and post- exercise in each group. We found that after exhaustion, the normal group showed higher erythrocyte superoxide dismutase (SOD) activity compared to the obesity group. At exhaustion, the normal group had lower HSP activity compared to the obesity group. Based on the results, an acute exercise of normally healthy people induced an up-regulation of superoxide dismutase (SOD) activity. This plays an important role in the protection of extra-cellular fluid components against peroxide-mediated damage.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.10
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• pp.3802-3807
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• 2010

In most sports, a key evaluator of athletic performance is sprinting speed. There are two trainable factors associated with speed including mechanical efficiency and force production. The squat exercise is one of the beneficial exercises implemented to enhance lower extremity power for sprinters. However, there has been little research on the optimal exercise intensity for sprinting performance. This study was to investigate whether performing different squat exercises prior to a 40m sprint would improve running speed. Ten male high school sprinters performed six 40m sprints following the different squat intensities (30%, 50%, 70%, and 90% of 1RM). A one-way ANOVA with repeated measures revealed that 40m sprint times had significantly improved after 50% ($5.27{\pm}0.13$, p<0.0001) and 70% ($5.26{\pm}0.15$, p<0.0001) of 1RM squat exercises compared to sprint times not following a squat % ($5.33{\pm}0.16$). Performing squat exercises with intensities of 50% and 70% of 1RM may improve 40m sprint times. Therefore, it is suggested that coaches and sprinters could include a medium intensity squat exercise (70%) in the warm-up procedure in order to improve sprint performance.

• Journal of the Korean Applied Science and Technology
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• v.35 no.2
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• pp.445-453
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• 2018

The purpose of this study was to analyze the effect of acute respiratory training feedback upon a change on HRV-Autonomic nervous system in middle-aged women. The research subjects were totally 24 middle-aged women(40-60 years old), were randomly allocated 12 people to the respiratory training group and 12 people to the control group, and then were carried out the acute respiratory training. The feedback exercise in the respiratory training group was conducted for totally 15 minutes. Following the 10-minute breath awareness training according to the expert's guidance, the 5-minute autonomous breathing exercise was implemented. The data analysis was carried out Repeated Measures ANOVA with SPSS WIN 20.0. The conclusions that were obtained through this are as follows. The middle-aged women got significantly higher in SDNN, RMSSD, LF, HF after the acute respiratory training. Compared to the control group. the respiratory training group was indicated to have gotten higher significantly in SDNN, RMSSD, LF, HF. Mean HR and LF/HF were not shown a significant difference in both the main effect of group & period and the interaction effect of group & period. Above of a result the acute respiratory training feedback is effective for SDNN, RMSSD, sympathetic activity, parasympathetic activity in the middle-aged women. Thereby, the respiratory training program improves autonomic nervous system, being considered to be possibly expected the effective value of exercise intervention available for relieving stress and recovering autonomic dysfunction in the middle-aged women.

• 한국게임학회지
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• v.10 no.1
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• pp.12-23
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• 2013

본 논문에서는 컴퓨터 게임공간의 레벨디자인을 기반으로 3D 공간에서 설계될 수 있는 트랩 유형을 제시하였다. 트랩은 게임 내의 장애물로서 3D 공간에서의 X, Y, Z 축으로의 이동방향, 고정, 운동, 회전, 스케일의 트랩 자체의 상태, 일회성, 반복, 순환의 작동타입 등의 요소를 바탕으로 표현된다. 트랩의 상태를 기준으로 작동 타입과 이동방향의 경우의 수를 조합한 결과 28가지의 트랩 유형이 도출되었다. 그리고 도출해낸 28가지의 트랩 유형이 실질적으로 게임공간에 적용되어 쓰이고 있는지 알아보기 위해 발리언트와 트라인 게임을 대상으로 트랩 유형을 살펴보았다.