• Title/Summary/Keyword: 일산화 질소

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Reactive oxygen species-dependent down-regulation of ubiquitin C-terminal hydrolase in Schizosaccharomyces pombe (Schizosaccharomyces pombe에서의 유비퀴틴 C-말단 가수분해효소의 활성산소종 의존성 하향조절)

  • Jo, Hannah;Lim, Hye-Won;Kwon, Hee-Souk;Lim, Chang-Jin;Park, Kwang Hark;Jin, Chang Duck;Kim, Kyunghoon
    • Korean Journal of Microbiology
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    • v.52 no.2
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    • pp.236-241
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    • 2016
  • The Schizosaccharomyces pombe $sdu1^+$ gene, belonging to the PPPDE superfamily of deubiquitinating enzyme (DUB) genes, was previously shown to encode a protein with ubiquitin C-terminal hydrolase (UCH) activity and to participate in the response against oxidative and nitrosative stresses. This work focused on the reactive oxygen species (ROS)-dependent regulation of the S. pombe $sdu1^+$ gene. UCH activities, encoded by the $sdu1^+$ gene, were attenuated in the S. pombe cells exposed to $H_2O_2$, superoxide radical-generating menadione (MD), and nitric oxide (NO)-generating sodium nitroprusside (SNP). Reduced glutathione (GSH) and its precursor N-acetylcysteine (NAC) were able to significantly enhance the UCH activities in the absence or presence of $H_2O_2$. However, the influences of both GSH and NAC on the ROS levels in the absence or presence of $H_2O_2$ were opposite to their effects on the UCH activities under the same conditions. The UCH activities in the Sdu1-overexpressing S. pombe cells were also diminished under exposure to $H_2O_2$, MD and SNP, but still remained to be higher than those in the vector control cells. In brief, it is proposed that the S. pombe $sdu1^+$ gene is regulated by ROS in a negative manner, the meaning of which largely remains elusive.

Effects of Dietary Supplementation of a New Probiotic CS61 Culture on Performance in Broiler Chickens (새로운 생균제 CS61 배양액의 사료 내 급여가 육계의 생산성에 미치는 영향)

  • Kim, Sung-Hwan;Lee, In-Chul;Baek, Hyung-Seon;Kang, Seong-Soo;Kim, Hyoung-Chin;Yoo, Jin-Cheol;Kim, Jong-Choon
    • Journal of Life Science
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    • v.22 no.3
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    • pp.340-346
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    • 2012
  • Bacterial resistance to antibiotics and residues of antibiotics in poultry products have encouraged the use of probiotics, prebiotic substrates, and synbiotic combinations of prebiotics and probiotics as alternative approaches to the use of antibiotics in poultry. The present study was carried out to evaluate the effect of a new probiotic CS61 culture on growth performance, feed conversion efficiency, and safety in broiler chickens, and to evaluate its value as an alternative for antibiotics used as a feed additive. Two dosages of CS61 culture (0.1% and 1%) were fed to chickens for 28 days. The results showed that terminal body weight and daily weight gain in the treatment groups increased in a dose-dependent manner when compared with the control group. Dietary supplementation with CS61 culture also improved feed conversion rate compared to the control group. There were no treatment-related toxic effects in terms of clinical findings, mortality, necropsy findings, hematology, or serum biochemistry parameters in any group tested. The nitric oxide assay showed that CS61 peptide has a dose-dependent inhibitory effect on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells. The results of this experiment indicated that dietary supplementation of CS61 culture may improve growth performance and feed conversion efficiency in chickens through its anti-inflammatory effect.

Production of NO in Interacting Laminar Diffusion Flames (상호작용하의 층류 확산 화염에서 NO의 생성)

  • 전철균
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.1
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    • pp.190-199
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    • 1993
  • In order to find the effect of flame interaction on NO production, dual laminar diffusion flames issuing from two rectangular nozzles were investigated theoretically. Chemical equilibrium model and Zeldovich mechanism were used in numerical model. The effect of four major parameters on NO production were inspected. These parameters are nozzle spacing, Raynolds number, aspect ratio of nozle cross section and velocity of secondary flow. It is found that interaction of flames enhances production of n. It is also found that multiflames with large spacing, small aspect ratio and strong secondary flow product less n.

Performance of a Pilot-scale Rice Husk Incinerator (파이로트 곡모 왕겨 소각로의 성능에 관한 연구)

  • M. H. Kim;C. S. Kim;S. J. Park
    • Journal of Biosystems Engineering
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    • v.22 no.1
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    • pp.21-29
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    • 1997
  • 왕겨 재를 분쇄하여 콘크리트 混和용 재료로 이용하려는 연구의 일환으煙로서, 파이로트 規模의 多目的 왕겨 燒却爐를 設計, 裂作하고 그 性能을 分析하였다. 왕겨 燃燒時의 熱에너지는 回收하여 원예施設의 煖房이나 콘크리트의 高溫 養生水로써 이용하고자 熱交煥裝置를 제작하여 왕겨 燒각爐시스템에 장착하였고, 排煙가스내의 이산화탄소가 시설원예 作物의 光合成에 이용될 수 있는지 排煙가스의 造成을 조사하였다. 분쇄된 왕겨 재의 큰크리트 混和材로서의 적합성은, 燃燒 灰分의 성분 중 $SiO_2$ 의 結晶化 상태를 分析함으로써 判斷하였다. 연구결과를 要約하면 다음과 같다. 1. 왕겨 灰分의$SiO_2$ 結晶化는 燃燒온도 $750^circ C$ 이하에서는 거의 발생하지 않는 것으로 분석되었다. 2. 燒却爐의 작동은 매우 만족스러웠으며 最適 작동조건은 왕겨供給率 15kg/h. 制御온도 $600^{\circ}C$로 分析되었다. 最適 작동조건에서, 왕겨燃燒率은 97%, 熱交換機 效率은 59.5%, 전체 시스템의 熱效率은 57.7%로서 양호하였으며, 灰分의 $SiO_2$ 結晶化도 거의 발생하지 않아 生成된 왕겨 灰分은 훌륭한 큰크리트 混和在로 판단 되었다. 3. 燒却爐내 溫度分布는 대체로 均一하였으며, 排煙가스내의 大氣오염물질 중, 질소酸化物과 황酸化物 함량은 許容기준치보다 매우 낮았으나 일산화탄소 함량은 許容기준값 부근으로 나타나 排煙가스를 직접 원예시설 내에 공급하기 위해서는 약간의 연소실 구조 개선이 필요하다고 판단되었다.

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A study on the condition of air pollution near tollbooths on highway (고속도로 요금소 주변의 대기오염 현황에 관한 연구)

  • 김신도;박성규;봉춘근;김종호;강혜진;이의상
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.11 no.3
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    • pp.359-368
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    • 1999
  • The outdoor and indoor air quality surrounding highway have been measured, and the study on the design of the booth shape and the air-conditioning system also has been carried out. For the first step of the work, the air quality at the Seoul tollgate on the Kyeong-bu highway was monitored over a year. The measured indoor air quality shows seasonal average concentration 85.6-92.1ppb of >;$NO_2$and the $SO_2$and CO lower than the EAQS(Environmental Air Quality Standards). The measured TSP concentration was much higher than the EAQS. In conclusion, there is necessity to improve the working environment of the tollbooths on highways, and the current air-conditions need to be modify for the purpose. In the process of modifying the air-conditioning system, particulate pollutants needs to be considered processing and the priority needs to be put on the booths for big vehicles.

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Analysis of time series models for PM10 concentrations at the Suwon city in Korea (경기도 수원시 미세먼지 농도의 시계열모형 연구)

  • Lee, Hoon-Ja
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.6
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    • pp.1117-1124
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    • 2010
  • The PM10 (Promethium 10) data is one of the important environmental data for measurement of the atmospheric condition of the country. In this article, the Autoregressive Error (ARE) model has been considered for analyzing the monthly PM10 data at the southern part of the Gyeonggi-Do, Suwon monitoring site in Korea. In the ARE model, six meteorological variables and four pollution variables are used as the explanatory variables for the PM10 data set. The six meteorological variables are daily maximum temperature, wind speed, relative humidity, rainfall, radiation, and amount of cloud. The four air pollution explanatory variables are sulfur dioxide ($SO_2$), nitrogen dioxide ($NO_2$), carbon monoxide (CO), and ozone ($O_3$). The result showed that the monthly ARE models explained about 13-49% for describing the PM10 concentration.

Application of AI-based model and Complex Network method for Comprehensive Air-Quality Index prediction (종합대기질 지수 예측을 위한 AI 기반 모형 및 Complex Network 기법 적용)

  • Kim, Dong Hyun;Song, Jae Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.324-324
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    • 2022
  • 정확한 오염물질 예측은 기상학, 자연재해, 기후변화 연구 등 현장에서 필수적인 과제 중 하나이다. 주변 관측소에서 얻은 데이터를 사용하는 경우 모델 학습을 위한 불필요한 데이터로 인해 예측 결과에 왜곡 문제가 있을 수 있습니다. 따라서, 우리는 종합적인 대기질 지수 행동에 영향을 미치는 요인을 제공하는 최적의 데이터 소스를 찾기 위해 네트워크 방식을 사용했습니다. 본 연구에서는 2015년부터 2020년까지 우리나라의 6개 오염물질과 종합적인 대기질 지수 예측에 대한 네트워크 기법을 적용한 LSTM 및 DNN 모델을 적용하였다. 본 연구는 미세먼지(PM10), 초미세먼지(PM2.5), 오존(O3), 이산화황(SO2), 이산화질소(NO2), 일산화탄소(CO) 등 6가지 오염물질을 기반으로 종합적인 대기질 지수를 예측하는 2단계로 구성되어 있다. LSTM을 이용하여, 개별적으로 예측된 6가지 오염물질을 이용하여 DNN 모형을 이용하여 종합적인 대기질 지수를 예측한다. 6가지 오염물질에 대한 각 모델의 예측능력과 종합적인 대기질 지수 예측은 관측된 대기질 데이터와 비교하여 평가하였다. 본 연구는 심층신경망 모델과 네트워크 방식을 결합한 것이 높은 예측력을 제공함을 보여주었으며, 종합적인 대기질 지수 예측을 위한 최적의 모델로 선정되었다. 재난관리의 필요성이 증가함에 따라 네트워크 방식의 딥러닝 모델은 자연재해 피해를 줄이고 재난관리를 개선할 수 있는 충분한 잠재력을 가질 것으로 기대된다.

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Survey on Ambient Air Quality in Pusan Areas (부산의 대기오염도 조사)

  • Kim, Y.W.;Kim, J.Y.;Lee, C.U.;Jun, J.H.;Moon, D.H.;Shin, H.R.;Lee, J.T.;Lee, M.C.;Kim, S.C.;Pae, K.T.
    • Journal of Preventive Medicine and Public Health
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    • v.19 no.2 s.20
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    • pp.252-262
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    • 1986
  • In order to assess the degree of atmospheric pollution and to contribute the health improvement of residents in Pusan, the authors measured CO, $SO_2,\;NO_2$ and TSP level at 3 places by season and time from July, 1985 to April, 1986. The places were Somyon, Sasang and Daeshin-dong, which were known as the commercial, industrial and residental area in Pusan, respectively. The obtained results were as follows: 1) The average concentration of CO was highest with $2.19{\pm}0.52$(3.5-1.0)ppm at Sasang area, and lowest with $1.32{\pm}0.55$(3.0-0.5)ppm at Daeshin-dong areas. 2) The average concentration of $SO_2$ was highest with $0.092{\pm}0.073$(0.378-0.028)ppm at Sasang, and lowest with $0.041{\pm}0.014$(0.083-0.019)ppm at Daeshin-dong. 3) The average concentration of $NO_2$ was highest with $0.069{\pm}0.012$(0.090-0.050)ppm at Somyon, and lowest with $0.043{\pm}0.010$(0.061-0.032)ppm at Daeshin-dong. 4) The average concentration of TSP was highest with $300{\pm}130(780-130){\mu}g/m^3$ at Sasang, and lowest with $160{\pm}80(390-70){\mu}g/m^3$ at Daeshin-dong. 5) The level of CO and TSP were highest in summer at Somyon and Daeshing-dong, and in winter at Sasang, respectively. The level of $SO_2$ and $NO_2$ were highest in winter and spring at all areas. 6) The level of all air pollutants were higher in the afternoon or night than in the morning.

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Characteristics of indoor air quality in the overground and underground railway stations (지상과 지하역사의 실내공기질 특성과 외기영향 평가)

  • Namgung, Hyeong-Kyu;Song, Ji-Han;Kim, Soo-Yeon;Kim, Hee-Man;Kwon, Soon-Bark
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.5
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    • pp.17-25
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    • 2016
  • In this study, the air quality of underground and overground railway stations was evaluated focusing on the degree of influence of the outside air quality. The measured components were particulate matter ($PM_{10}$), carbon dioxide ($CO_2$), carbon monoxide (CO), nitrogen dioxide ($NO_2$), formaldehyde (HCHO), ozone ($O_3$), total airborne bacteria (TAB), total volatile organic carbon (TVOC), and Radon (Rn), which are included in the maintenance standards and recommended standards of the Indoor Air Quality Management Act. Also, the indoor/outdoor concentration ratios of $PM_{10}$, $NO_2$, and $O_3$ were calculated to estimate the influence of the outdoor air quality. The concentrations of $PM_{10}$ HCHO, TVOC, $NO_2$, and Rn in the underground stations were found to be higher than those in the overground stations. These results indicate that the (present) generation of contaminants are caused by the indoor source of the underground station. The ozone concentration of the overground stations was higher than that of the underground stations, which indicates that the outdoor ozone concentration influenced that of the overground stations directly. Thus, methods of improving the IAQ should take into consideration the types of contamination.

Variation of nitric oxide concentrations in response to shaking stress in the Manila clam Ruditapes philippinarum (일산화질소 (nitric oxide) 정량을 통한 바지락(Ruditapes philippinarum) 의 흔들림 스트레스 측정)

  • Park, Kyung-Il
    • The Korean Journal of Malacology
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    • v.29 no.1
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    • pp.1-6
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    • 2013
  • This study aimed to evaluate the effects of shaking stress in the hemolymph of the Manila clam Ruditapes philippinarum by quantification of nitric oxide (NO) levels. The clams were divided into 3 groups as follows: clams placed in a plain container (control), clams injected with nitro-L-arginine methyl ester (NAME, an NO inhibitor), and clams in a container filled with nylon fiber at a density of $1kg/m^3$. Subsequently, each group was placed in sea water and shaken at 100 rpm for 6 h. The concentration of NO was quantified by using DAF assay and Griess assay. Both the assays showed that while shaking significantly increased the NO concentration, the NO inhibitor reduced the NO concentration in the hemolymph of the clams tested. In addition, the nylon fiber, which was used as a filler, effectively prevented the increase in NO concentration. This result suggests that measurement of NO concentration is a useful tool for evaluation of physiological stress in marine bivalves. In addition, it should be considered that a filler is necessary when dredge fishing or the suspended clam culture method is developed.