• Monthly Duck's Village
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• s.55
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• pp.46-50
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• 2008

2008년 무자년을 맞이하여 "월간 오리마을"로부터 원고를 부탁받고 잠시 망설였다. 어떠한 내용을 쓰는가 하는 문제보다는 오리와 조류인플루엔자 바이러스와의 관계를 정확하게 전달할 수 있을까하는 마음에서였다. 오리에서의 고병원성 조류인플루엔자는 매우 민감한 문제이기 때문에 정확하게 표현을 하지 못한다면 아니 쓰지만 못할 것이기 때문이다. 하지만 나름대로 최선을 다해서 정확하게 표현을 함으로서 앞으로 우리 앞에 다가올지도 모르는 어려움을 사전에 대처하는 방법을 생각하는 시간을 갖기로 하였다. 이미 고병원성 조류인플루엔자에 대해서는 너무 많은 매체에 의하여 발표가 되었고 오리농가들도 생계와 직결되는 것인 만큼 나름대로 다양한 자료를 접했으리라 판단된다. 따라서 이 원고에서는 기본적인 내용은 생략을 하고 우리가 기억을 되살려서 개념적으로 강조가 필요한 부분만을 언급하고자 한다.

• KOREAN POULTRY JOURNAL
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• v.52 no.8
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• pp.112-115
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• 2020

농림축산검역본부(본부장 박봉균, 이하 검역본부)는 지난 6월 16일 세계동물보건기구(OIE)에서 조류인플루엔자 OIE 표준실험실 인증을 받았다. 아시아 최초 8개의 OIE 표준실험실을 보유하면서 이번 계기로 조류인플루엔자 진단·연구 및 방역분야에서 국제적 신인도 확보는 물론 아시아 지역에서 선도기관이 될 것으로 기대된다. 검역본부 조류인플루엔자연구진단과 이명헌 과장을 만나 그간 활동과 OIE 표준실험실 인증 획득의 의미와 향후 일정 등 앞으로 활동 계획에 대해 인터뷰했다.

• Pediatric Infection and Vaccine
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• v.23 no.2
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• pp.87-93
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• 2016

Purpose: An outbreak of influenza virus is uncommon in neonatal intensive care unit (NICU). The clinical presentation of influenza virus infection in neonates is diverse. This study was aimed to report an outbreak of influenza A in a NICU and to investigate the clinical characteristics of influenza virus infection in neonates especially preterm infants during the 2011-2012 influenza season in Korea. Methods: We reviewed the medical records of 29 patients who were evaluated by respiratory virus multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) at NICU of Kosin University Gospel Hospital during the 2011-2012 seasonal influenza outbreak in Korea. Results: Eleven patients (37.9%) were influenza A virus RT-PCR positive during the survey periods. They were all preterm infants and three of them had no symptoms. Eight patients had symptoms and it was fever (18%, 2/11), respiratory difficulty (72.7%, 8/11) without symptoms of upper respiratory infection, and gastrointestinal symptoms (27.3%, 3/11). The median duration of symptom was 5 days. There were differences of duration of admission at the test of respiratory RT-PCR, Clinical Risk Index for Babies (CRIB) score, use of mechanical ventilation, and use of dexamethasone before infection between influenza A virus RT-PCR positive and negative group. All 11 patients with influenza A were discharged without any complications. Conclusions: The symptoms of influenza A virus infection in the preterm infants is nonspecific. Influenza A virus should be considered as a possible cause of infection in NICU during the influenza season in the community.

• Pediatric Infection and Vaccine
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• v.21 no.1
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• pp.1-8
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• 2014

Purpose: The aim for this study was to investigate clinical manifestation of seasonal influenza A and B during the 2012 winter season in Wonju, South Korea. Their clinical and laboratorial characteristics and effect of oseltamivir were compared and analyzed. Methods: Children under the age of 18 years who visited the Wonju Severance Christian Hospital with fever or acute respiratory symptoms and who were diagnosed with influenza A or B by rapid antigen test from nasopharyngeal swab were selected for the study. The medical records of patients were retrospectively reviewed. Results: Influenza A was detected in 374 patients (83.7%), and influenza B in 72 (16.6%). The incidence of influenza A was highest in February (n=186), while that of influenza B was highest in March (n=36). The most common symptoms were fever (n=434, 97.1%) and cough (n=362, 81.0%). No significant differences were observed between influenza A and B in symptoms and laboratory data. Patients who had used oseltamivir within 2 days showed statistically lower admission rate, shorter admission duration, and lower incidence of pneumonia. Conclusion: This study found no statistical difference between influenza A and B, in symptoms, progression, and laboratory test, but those who were treated with oseltamivir given within 2 days of the onset of fever experienced more positive outcomes.

• Korean Journal of Microbiology
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• v.41 no.1
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• pp.53-59
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• 2005

Influenza is an important public health problem which occurs almost every winter in temperate climates and is often associated with increased rates of hospitalization and death. In 1999, our influenza surveillance was initiated with 4 voluntary sentinel physicians and the Public Health Center. During the 2003-2004 influenza season, 124 influenza viruses were isolated from 401 clinical specimens, which were collected from patients with Influenza-like illness(ILI) in Seoul. The case definition of ILI is a case with fever more than $38^{\circ}C$ and systemic symptoms; cough, or sore throat. ILI was the highest at the 20-49 age $group(23\%)$ and the rate of virus isolation was the highest at the 7-19 age $group(50\%)$. Among 124 influenza viruses, isolates 83 were identified as A/H3N2 type and others were subtyped as influenza B viruses in 2003-2004 season. Influenza viruses were collected $39.1\%$ at Nowon-Gu, $13.5\%$ Gangnam-Gu and Seocho-Gu etc. and the isolate rate of virus had the area difference; Yongsan-Gu $66.7\%$, Gangnam-gu $50.0\%$, Nowon-Gu $39.9\%$, Kangbuk-Gu $36.8\%$, Seocho-Gu $27.8\%$, Dongjak-Gu $21.2\%$. Out of 401 individuals, 160 was vaccinated $(40\%)$ and the vaccination rate was the highest at the 20-49 age $group(32\%)$. These findings may contribute to the recommondation of the influenza vaccine formulation and the development of influenza control measure.

• Journal of the Korean Child Neurology Society
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• v.26 no.4
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• pp.221-226
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• 2018

Purpose: Febrile seizures (FSs) are the most common type of seizure in the first 5 years of life and are frequently associated with viral infections. Influenza infection is associated with a variety of neurological conditions, including FSs. The purpose of this study was to evaluate the clinical implications of influenza infection in FSs. Methods: In total, 388 children with FS were divided into two groups: FS with influenza infection (n=75) and FSs without influenza infection (n=313). Their medical records, including seizure type, frequency, duration, and familial history of FSs or epilepsy, were retrospectively reviewed and the clinical characteristics of the two groups were compared. Results: In total, 75 of the 388 children (19.3%) had FSs associated with influenza infection; such children were significantly older than those with FSs without influenza infection ($34.9{\pm}22.3$ months vs. $24.4{\pm}14.2$ months; P<0.001). The children who had more than two febrile seizures episodes were more prevalent in children with FS with influenza infection [40/75 (53.3%) vs. 92/313 (29.4%); P<0.01]. Children older than 60 months were more likely to have influenza infection compared to those aged less than 60 months [11/22 (50%) vs. 64/366 (17.5%); P=0.001]. Conclusion: Influenza infection may be associated with FSs in older children, and with recurrence of FSs. Its role in the development of afebrile seizures or subsequent epilepsy requires further investigation with long-term follow-up.

• The Microorganisms and Industry
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• v.31 no.1
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• pp.43-46
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• 2005

• The Journal of the Korea Contents Association
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• v.13 no.4
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• pp.300-311
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• 2013

The aim of this study was to investigate the factors influencing on influenza vaccination among socio-demographic characteristics and health behaviors. Data of 18,299 adults of age between 19 and 65 years who answered to the survey on National Health and Nutrition and influenza vaccination from 2007 to 2010 was used and analyzed. Overall influenza vaccination rate was 21.7%. Logistic regression analysis revealed that factors influencing on influenza vaccination were an increasing age, a residence in rural area, a high personal income, a low educational level, jobless women, experience of hospital visits, and morbidity of chronic illnesses. In conclusion, influenza vaccination rate in Korea is low and influenced by multiple socio-demographic factors and health behaviors. It is needed to seek a strategy to develop a vaccination program in consideration of factors associated with influenza vaccination.

• Monthly Duck's Village
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• s.60
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• pp.78-80
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• 2008

AI로 인해 급감한 소비를 회복시키고 소비자들을 안심시키기 위해 의료계와 식품산업계가 나섰다. 대한의사협회(이하 의협) 국민의학지식향상위원회가 20일 '조류인플루엔자 문제에 대한 심포지엄'을 개최하고 의학계, 수의학계, 보건당국 전문가들로부터 AI 인체감염을 예방하기 위한 대처방안들을 제시하였다. 조류인플루엔자(AI)가 실제 사람에게 감염될 가능성은 희박하다는 게 현재까지의 중론이지만 만약의 상황에 대비해 AI 감염요인과 예방법을 올바로 숙지해야 한다는 의견이 제기됐다.

• KOREAN POULTRY JOURNAL
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• v.40 no.5 s.463
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• pp.102-106
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• 2008

그 동안의 통념을 깨고 겨울이 아닌 4월에 고병원성 조류인플루엔자(HPAI)가 발생하면서 이제는 1년 내내 AI에 대한 대비책을 세워야 할 것으로 보인다. 정부에서도 방역활동을 상시체제로 전환하면서 AI 방지를 위해 최선의 노력을 기울이고 있다. 본고는 AI 발생시 양계 농장에서 취해야 할 내용 중 '조류인플루엔자 긴급행동지침'을 중심으로 알아야 할 내용을 발췌.요약.게재 하였다.