• Radiation Oncology Journal
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• v.14 no.3
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• pp.247-253
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• 1996

Purpose : The dose calculation program for the Buckler type remote after-loading system was developed. This program also can be used to calculate dose for various sealed sources. Materials and Methods : We determined the source length and distribution by dividing the program disk to 72 points. The dose rate for the each program disk and source was calculated. The dose rate table for the xy coordinate was established. The dose rate for the interesting points of the patient were calculated by using this table, We also made isodose curve from this calculations. Results : The storage size for the dose rate table were increased. But the calculation of the dose rate for the patient were carried out rapidly. So we could get real time calculation. Conclusion : By using this program, we could calculate the dose rate for the various points of the patient quickly and accurately. This program will be useful for the treatment with various linear sources.

• The korean journal of orthodontics
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• v.27 no.6 s.65
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• pp.955-961
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• 1997

Nicotine is one of the major components of cigarette smoking which causes various systemic and local diseases to human body. Mitogenic effects of nicotine to systemic disease are interesting factors in the results of cellular Proliferation especially to vascular and pulmonary tissue or cells. The study of local effects concerns with destruction of tissue and delayed healing rate after various surgical treatment. Platelet-Derived Growth factor(PDGF) and Insulin-like growth factor(IGF) are blown as major mitogens to human PDL cells. The purpose of this study was to investgate the mitogenic effects of nicotine to human PDL cells. We studied the expression of PDGF-$\alpha$ receptor, PDGF-$\beta$receptor, and IGF-l receptor mRNA from the nicotine treated human PDL cells by northern analysis. The experimental groups were divided into different serum($1\%,\;10\%$) and nicotine (100ng/m1,1000ng/m1) concentrations and each group was studied by time course. The results of this study showed upregulation of PDGF-${\alpha},\;{\beta}$ receptor and IGF-l receptor mRNA at 100ng/ml nicotine concentration and $10\%$ serum group to the time course. These results suggest that physiologically attainable nicotine concentrations may stimulate the mitogenic gene synthesis to human PDL cells in vitro.

• Progress in Medical Physics
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• v.27 no.1
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• pp.37-45
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• 2016

In proton therapy, in vivo proton beam range verification is very important to deliver conformal dose to the target volume and minimize unnecessary dose to normal tissue. For this purpose, a multi-slit prompt-gamma camera module made of 24 scintillation detectors and 24-channel signal processing system is under development. In the present study, we have developed and tested a dual-mode signal processing system, which can operate in the energy calibration mode and the fast data acquisition mode, to process the signals from the 24 scintillation detectors. As a result of performance test, using the energy calibration mode, we were able to perform energy calibration for the 24 scintillation detectors at the same time and determine the discrimination levels for the detector channels. Further, using the fast data acquisition mode, we were able to measure a prompt-gamma distribution induced by a 45 MeV proton beam. The measured prompt gamma distribution was found similar to the proton dose distribution at the distal fall-off region, and the estimated beam range was $17.13{\pm}0.76mm$, which is close to the proton beam range of 16.15 mm measured by an EBT film.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.2 no.2
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• pp.3-8
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• 2009

The traction system has been mainly used for rehabilitation and correction of patients with spine or gait diseases in orthopedics or at home. Some problems could occur in human body when patients forced their training using the traction system. So it needs to measure a traction force and control the training time. However, most of products on market have no sensor measuring traction force. Thus we designed and made a sensor detecting traction force using strain gauge, amplifier for transition to output signal and experiment devices for performance test. We carried out experiment of a sensor detecting a traction force and measured electric responses of it with respect to traction loads. Maximum error was within about 1% for experiments in static condition and the average error was about 0.7% for experiments in dynamic condition. We concluded that it is possible to use the developed sensor for measurement of traction force since the maximum output variation of a sensor detecting a traction force was about 0.3% in $0^{\circ}C-60^{\circ}C$ temperature condition.

• Korean Journal of Plant Resources
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• v.36 no.5
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• pp.527-539
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• 2023

Pepper (Capsicum annuum L.) is an important vegetable and spice crop that has been cultivated worldwide. Pepper fruits have unique taste and aroma, providing a variety of antioxidants and compounds important for human health, which makes a high economic value. In addition, there is a high demand for new pepper varieties, according to consumer's preference. However, pepper is a recalcitrant plant for in vitro tissue and organ differentiation and plant regeneration, which makes it difficult to develop demanded varieties using newly developed technologies such as genetic engineering and gene editing. In this study, tissue culture and regeneration conditions were investigated using seven pepper varieties that were obtained from the core-collection of Seoul National University. We observed callus and bud induction and shoot formation using several media composition composed of different cytokinins and auxin concentrations. As a result, it was found that there were differences in callus induction and shoot formation of each variety depending on the hormone composition, and the highest regeneration was shown when the medium containing Zeatin Riboside and the petioles of seedlings were used. In particular, out of seven pepper varieties, CMV980 exhibited a higher regeneration efficiency (approximately 48%) than other varieties, followed by Yuwolcho. Therefore, this study provides CMV980 and Yuwolcho as good candidates that can be used for pepper transformation, which might contribute to the development of various varieties through gene editing technology in the future.

• The korean journal of orthodontics
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• v.30 no.2 s.79
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• pp.197-204
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• 2000

[$K^+$]-selective ion channels were studied in excised inside-out membrane patches from human osteoblast-like cells (G292). Three classes of $K^+$channels were present and could be distinguished on the basis of conductance. Conductances were $270\pm27\;pS,\;113\pm12\;pS,\;48\pm8\;pS$ according to their approximate conductances in symmetrical 140 mM KCl saline at holding potential of -80 mV It was found that the small conductance (48 pS) $K^+$channel activation was dependent on membrane voltage. In current-voltage relationship, small conductance $K^+$channel showed outward rectification, and it was activated by the positive potential inside the membrane. In recordings, single channel currents were activayed by a negative pressure outside the membrane. The membrane pressure increased $P_{open}$ of the $K^+$ channel in a pressure-dependent manner. In the excised-patch clamp recordings, G292 osteoblast-like cells have been shown to contain three types of $K^+$ channels. Only the small conductance (48 pS) $K^+$channel is sensitive to the membrane stretch. These findings suggest that a hyperpolarizing current, mediated in part by this channel, may be associated with early events during the mechanical loading of the osteoblast. In G292 osteoblast-like cells, $K^+$channel is sensitive to membrane tension, and may represent a unique adaptation of the bone cell membrane to mechanical stress.

• The Journal of Korean Society for Radiation Therapy
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• v.19 no.1
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• pp.27-33
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• 2007

Purpose: We have performed SRS (stereotactic radiosurgery) for avm (arterry vein malformation) and brain cancer. In order to verify dose and localization of SRS, dose distributions from TPS ($X-Knife^{(R)}$ 3.0, Radionics, USA) and GafChromic $EBT^{(R)}$ film in a head phantom were compared. Materials and Methods: In this study, head and neck region of conventional humanoid phantom was modified by substituting one of 2.5 cm slap with five 0.5 cm acrylic plates to stack the GafChromic $EBT^{(R)}$ film slice by slice with 5 mm intervals. Four films and five acrylic plates were cut along the contour of head phantom in axial plane. The head phantom was fixed with SRS head ring and adapted SRS localizer as same as real SRS procedure. CT images of the head phantom were acquired in 5 mm slice intervals as film interval. Five arc 6 MV photon beams using the SRS cone with 2 cm diameter were delivered 300 cGy to the target in the phantom. Ten small pieces of the film were exposed to 0, 50, 100, 200, 300, 400, 500, 600, 700, 800, 900 cGy, respectively to calibrate the GafChromic $EBT^{(R)}$ film. The films in the phantom were digitized after 24 hours and its linearity was calibrated. The pixel values of the film were converted to the dose and compared with the dose distribution from the TPS calculation. Results: Calibration curve for the GafChromic $EBT^{(R)}$ film was linear up to 900 cGy. The R2 value was better than 0.992. Discrepancy between calculated from $X-Knife^{(R)}$ 3.0 and measured dose distributions with the film was less than 5% through all slices. Conclusion: It was possible to evaluate every slice of humanoid phantom by stacking the GafChromic EBT film which is suitable for 2 dimensional dosimetry, It was found that film dosimetry using the GafChromic $EBT^{(R)}$ film is feasible for routine dosimetric QA of stereotactic radiosurgery.

• Journal of the Korean Society of Radiology
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• v.14 no.3
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• pp.221-233
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• 2020

CT(computed tomography, CT) examinations is one of the most useful diagnostic equipment for identifying information in the human body in diagnostic radiology. Recently, the number of CT scans is increasing every year due to the high reliability of CT scans. Increasing the number of tests will accelerate the aging of CT devices, which is why the importance of quality management for CT devices is on the rise. Particularly in CT, quality management refers to a behavior of figuring out and correcting all sorts of hindrance factors that can cause all the problems related to the equipment associated with the diminishment of diagnosed area due to the reduction of image quality in clinical imaging in advance and maintaining a consistent level of image quality and obtaining a proper image. Here, these researchers aim to summarize and report the general contents of quality management in CT.

• Journal of Korean Physical Therapy Science
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• v.6 no.2
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• pp.1041-1062
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• 1999

This study is to stimulate the model of which top notch muscle stimuli physical therapy has been made on the basis of GCM. GCM has been studied on the hypermobility & hypomobility pattern on the part of spine & extremity, and the body characteristics of four body types, which is the tilting of seal scapular & ilium. The purpose of this study is to analysize the type of GCM which has been focused on the spine & extremity for the patients having dysfunctions of neuromuscular system, being analysized the movement. The result of this study is as following; 1) The First hypothesis: The hypermobility & hypomobility pattern assorted by the tilting of scapular & ilium, as does the former study analysize was claimed that it would be in line with the pattern for hypermobility hypomobility and physical characteristics according to each body type at the percentage of at least 60(p<.001). 2) The 2nd hypothesis : Stimuli therapy of muscle dealing with physical characteristics and joint hypermobility hypomobility has the important role in restoring the deformity and keeping anatomical postural plumb alignment also it would a highly effects on correcting the body even though the stimuli area was limited to four areas and it was lack of time compared with those applied by general physical therapy(p<.001). As above the result, the top-notch type for physical therapy based on hypermobility hypomobility pattern by 4 body types which has been studied on tilting of scapular & ilium is more specificed and specialized than those of general physical therapy technologies. So this study will be believed to dedicate to restoration ideal anatomical postural plumb alignment based on spinal Manipulation and the concept of whole person as well as to being simple and effective to apply.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.6
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• pp.24-34
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• 2007

Application systems that easy to access a information have been developed by IT growth and a human life variation. In this paper, we propose a application system to register a 3D footwear model using a monocular camera. In General, a human motion analysis research to body movement. However, this system research a new method to use a foot movement. This paper present a system process and show experiment results. For projection to 2D foot plane from 3D shoe model data, we construct processes that a foot tracking, a projection expression and pose estimation process. This system divide from a 2D image analysis and a 3D pose estimation. First, for a foot tracking, we propose a method that find fixing point by a foot characteristic, and propose a geometric expression to relate 2D coordinate and 3D coordinate to use a monocular camera without a camera calibration. We make a application system, and measure distance error. Then, we confirmed a registration very well.