• 재활복지
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• v.17 no.4
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• pp.401-420
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• 2013

This study was performed to investigate the impact of the Neurocognitive Rehabilitation Therapy on the upper limb function recovery of patients with stroke and their abilities to perform daily activities and to provide basic data for a long-term treatment. A total of 30 patients with hemiplegia that occurred due to stroke were recruited as subjects of the present study, and 15 patients were randomly assigned to a Neurocognitive Rehabilitation Therapy group and a conventional treatment group, respectively. And, tests were performed over four weeks, five times a week, and 30 minutes a session. Manual Function Test(MFT), Fugl-Meyer Assessment Scale(FMA), and Korean-Modified Bathel Index(K-MBI) were used to measure the degree of the functional recovery before and after the experiment. According to the data of this study, in the upper limb function test, the Neurocognitive Rehabilitation Therapy group showed significant increase of the measurement values of MFT and FMA(p <.05), and when the difference between the two groups were compared, the upper limb function showed a statistically significant difference. In the daily activity performance test, only the Neurocognitive Rehabilitation Therapy group showed a significant improvement of K-MBI value(p <.05). Based on the results of the present study, it was demonstrated that the Neurocognitive Rehabilitation Therapy was effective in enhancing the upper limb functions and daily activity performance of patients with stroke.

• Therapeutic Science for Rehabilitation
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• v.10 no.3
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• pp.7-22
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• 2021

Objective : The purpose of this study was to verify the effect of virtual reality interventions (VRIs) on cognitive function in individuals with stroke through a systematic literature review and meta-analysis. Methods : We reviewed randomized controlled trials (RCTs) the last 10 years using academic databases. PubMed, MEDLINE, and CINAHL were used for international studies, and DBpia, KISS, Kyoboscholar, and e-article were used for Korean studies. For the quantitative meta-analysis, subgroups of outcomes were classified into general cognitive function (G-CF), attention and memory (A&M), and executive function (EF). Results : Nine RCTs were analyzed. The total number of participants was 271 (140 in the experimental group). The effect size (Cohen's d) was estimated using a random effects model. The effect sizes of the outcome subgroups of were as follows: small to medium for G-CF (d=0.422; 95% CI: 0.101~0.742; p=0.010), small for A&M (d=0.249; 95% CI: -0.107~0.605; p=0.170), and medium for EF (d=0.666; 95% CI: 0.136~1.195; p=0.014). Conclusion : Considering the various stimuli provided by the virtual environment and the results from available research, virtual reality should be applied to interventions for integrated cognitive functions. In addition, it would be appropriate to be used as an additional intervention to traditional cognitive rehabilitation for stroke.

• Sleep Medicine and Psychophysiology
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• v.20 no.1
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• pp.15-21
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• 2013

Objectives: Cognitive impairment in restless legs syndrome (RLS) patients can be affected by sleep deprivation, anxiety and depression, which are common in RLS. The objective of this study is to investigate relationship between cognitive impairment and RLS in the non-medicated Korean elderly with controlling for psychiatric conditions. Method: The study sample for this study comprised 25 non-medicated Korean elderly RLS patients and 50 age-, sex-, and education- matched controls. All subjects were evaluated with comprehensive cognitive function assessment tools- including the Korean version of Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K), severe cognitive impairment rating scale (SCIRS), frontal assessment battery (FAB), and clock drawing test (CLOX). Sleep quality and depression were also assessed with Pittsburgh sleep quality index (PSQI) and geriatric depression scale (GDS). Results: PSQI and GDS score showed no difference between RLS and control group. There was no significant difference between two groups in nearly all the cognitive function except in constructional recognition test, in which subjects with RLS showed lower performance than control group (t=-2.384, p=0.02). Subjects with depression ($GDS{\geq}10$) showed significant cognitive impairment compared to control in verbal fluency, Korean version of Mini Mental Status Examination in the CERAD-K (MMSE-KC), word list memory, trail making test, and frontal assessment battery (FAB). In contrast, no difference was observed between subjects who have low sleep quality (PSQI>5) and control group. Conclusions: At the exclusion of the impact of insomnia and depression, cognitive function was found to be relatively preserved in RLS patients compared to control. Impairment of visual recognition in RLS patients can be explained in terms of dopaminergic dysfunction in RLS.

• The Journal of the Korea Contents Association
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• v.18 no.11
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• pp.527-539
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• 2018

Cognitive decline in aging is known to yield detrimental effects in syntactic processing and working memory capacity is the most crucial cognitive function in understanding older adults' sentence processing skills. This study examined how young and older adults utilize contextual information while resolving NP-attached Ps vis word-by-word self-paced reading paradigm. In addition, the study asked which cognitive functions play roles on the use of a NP-supporting context during processing of NP-attached PP. When NP-attached PP was presented in a supporting context, both age groups performed faster than in the null context condition. Among different cognitive functions, alternating attention skills were correlated with the ability utilizing context during syntactic ambiguity resolution and working memory capacity was not found to be crucial for this study. In conclusion, this study suggests that aging does not always affect older adults' syntactic processing negatively and relevant cognitive function may vary depending on the type of syntactic structure.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04d
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• pp.626-628
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• 2003

인터넷에 접속하여 웹 컨텐츠를 이용할 수 있는 장치의 종류가 다양해짐에 따라 장치 독립적으로 웹 컨텐츠를 제공할 수 있는 기술의 필요성이 커지고 있다. 장치 독립적으로 웹 컨텐츠를 제공하기 위해서는 동적으로 전송 환경을 인지한 후 인지된 전송 환경에 적합한 형태로 컨텐츠를 조합 및 변환할 수 있어야 한다. 본 논문은 전송 환경을 인지하기 위해 필요한 전송 환경 해석 기능을 효과적으로 수행할 수 있는 규칙 기반 전송 환경 해석 기법을 설명한다. 본 기법을 활용하면 유연하고 동적인 변환 시스템 구축이 가능하므로 변환 기능의 손쉬운 변형 및 확장, 새로운 전송 환경에 대한 적응성 향상 등의 장점을 취할 수 있다.

• 건강소식
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• v.35 no.10
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• pp.18-20
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• 2011

치매(dementia)는 라틴에게서 유래된 말로서 '정신이 없어진 것' 이라는 의미를 갖고 있다. 태어날 때부터 지적 능력이 모자라는 경우를 정신지체(mental retardation)라고 부르는 반면, 치매는 후천적인 뇌질환이다. 즉, 정상적으로 생활해 오던 사함이 후천적인 뇌 손상으로 인하여 기억력, 언어능력, 방향감각, 판단력 등의 인지기능을 잃어가는 것이다. 또한 이런 인지 기능 장애가 심각하여 일상생활에 상당한 지장이 나타날 때 치매라고 한다.

• Tuberculosis and Respiratory Diseases
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• v.39 no.1
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• pp.7-14
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• 1992

Background: Cognitive deficit by hypoxia and/or hypercapnia is one of neuropsychological impairments frequently observed in patients with chronic obstructive pulmonary disease (COPD). The degree of cognitive deficit is variable among patients with similar level of hypoxia and/or hypercapnia, although a cause of this individual difference is well not known. COPD can be divided into two characteristic clinical entities including predominant emphysema and predominant bronchitis. This study was designed to evaluate the individual difference in cognitive deficit respond to hypoxia and/or hypercapnia in patients with COPD. Method: Sixteen patients with COPD (9 emphysema-dominant and 7 bronchitis-dominant) participated in this study. On admission arterial blood gas analysis and trail-making B (TMB) test for the evaluation of cognitive function were done in all patients. Mean TMB scores and the correlations between TMB scores and arterial blood gases were compared between two clinical groups. Results: 1) Mean TMB scores and arterial blood gases between two clinical groups were not different. 2) There was a tendency to be higher TMB score in hypoxemia, acidemia, and hypercapnia. However these findings were not statistically significant. 3) In emphysema-dominant group, $PaCO_2$ was mostly well correlated with TMB score (r=0.693). 4) In bronchitis-dominant group, arterial pH was mostly well correlated with TMB score (r=-0.526). Conclusion: Our data suggest that the individual difference in cognitive deficit respond to hypoxia and/or hypercapnia in patients with COPD may be dependent on their clinical entities, and arterial blood gases mostly well correlated with cognitive function that may be different according to their clinical entities.

• Korean Journal of Food Science and Technology
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• v.53 no.3
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• pp.278-289
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• 2021

The rapid aging of society has led to a surge in cognitive dysfunction in the elderly. As there is limited evidence for the development of dementia in medicine, a shift in focus on prevention strategies using bioactive compounds in food is required. This systematic review evaluated the effects of various bioactive compounds on age-associated cognitive decline. The literature was searched for terms related to bioactive compounds in cognitive decline and article selection was limited to clinical randomized controlled trials for a single bioactive compound. We identified 21 studies that evaluated the strength of the evidence. ω-3 fatty acids and vitamin B presented a strong evidence level, whereas vitamin D and E, anserine/carnosine, and chromium were defined as having moderate levels of evidence. ω-3 fatty acids relieved cognitive decline and reduced amyloid β-related protein accumulation. Vitamin B decreased homocysteine levels, which is accompanied by alleviation of cognitive function. In conclusion, ω-3 and vitamin B have the potential to improve age-associated cognitive decline.

• Korean Journal of Biological Psychiatry
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• v.1 no.1
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• pp.109-116
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• 1994

It is not known whether negative symptoms and cognitive functions are dissociable or improvements in symptoms are reflected in improvements in cognitive functions in chronic schizophrenic patients. We administered clozapine to evaluate its effect on cognitive functions in chronic schizophrenic patients and to show correlations between improvement in psychotic symptoms and in cognitive functions. Neuropsychological tests such as Wisconsin Card Sorting Test, Digit Span test and Judgment of Line Orientation Test were applied to 16 chronic schizophrenic patients at baseline and after 9 months of treatment with clozapine. Using BPRS we assessed psychopathology before initiation of clozapine and at 9 months. Clozapine improved both positive and negative symptoms in chronic schizophrenic patients significantly. After nine months of clozapine treatment, significant improvements occurred in attention, short-term memory and visual perception ability. And interestingly we noted the trend of improvement in executive functions even though they were not statistical significant. Any significant correlations between the clinical improvement and change in congnitive functions were not observed. Long-term treatment with clozapine improved parts of cognitive functions of chronic schizophrenics. The results of the study suggest that deficits in simple cognitive functions as well as psychotic symptoms are improved after 3 month period of short-term treatment, but executive functions requiring more sophisticated processing of information could be improved after more than 9 months of long-term treatment.

• The Journal of Korean society of community based occupational therapy
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• v.6 no.2
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• pp.1-10
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• 2016

Objective : The purpose of this study was to examine the effect of multi-sensory stimulation training on cognitive function and balance skill of the community resident elderly. Methods : 10 participants who is over aged 65 years carry out multisensory stimulation training program for 12weeks, once a week for 60minutes. The multisensory stimulation training program is consisted of total 12 topic based on body schema, gross muscle and tactile stimulation. The result was measured using Mini-Mental State Examination-Korean and Berg Balance Scale to evaluate before and after of cognitive function and balance skill. And after intervention, the satisfaction of the program was investigated. Wilcoxon matched-pair signed rank test was used to compare pre- post difference of cognitive function and balance skill. Results : There was significant difference in cognitive function and balance skill(p<.05) and the satisfaction is positive at the end of the program. Conclusion : The multisensory stimulation training program has positive effects on cognitive function and balance skill for elderly. And the satisfaction is positive at the end of the program. The multisensory stimulation training program can enhance the satisfaction to elderly in the aging society. So, additional studies is needed for efficient use.