• Journal of the Korean Society of Food Science and Nutrition
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• 제22권3호
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• pp.323-327
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• 1993

The effect of soyasaponin on the liposomal phospholipid membrane was investigated by differential scanning calorimetry (DSC). Soyasaponins were obtained and the enthalpy changes and the sizes of cooperative unit of the transition were calculated. The thermograms of L-$\alpha$-dimyristoyl phosphatidylcholine (DMPC) incorporated with soyasaponin showed that the phase transition temperature was significantly lowered and the peak was broadened. This was attributed to the possibility that incorporation of soyasaponin into the lipid bilayers reduced the cooperative unit of phospholipid bilayers. These results indicate soyasaponin might have significant effect on the fluidity of biological membrane.

• Proceedings of the Korean Society of Computer Information Conference
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• 한국컴퓨터정보학회 2022년도 제66차 하계학술대회논문집 30권2호
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• pp.307-310
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• 2022

4차 산업혁명의 기술이 발전함에 따라 세계는 눈부시게 발전하고 있다. 그러나 그와 동시에 어르신들의 치매로 인한 사회적 비용의 증가로 발생하는 문제점 또한 무시하지 못할 수준에 이르렀다. 이에 조기에 치매를 선별하여 예방하는 것이 중요시되었으며 다양한 연구기관에서는 빠르고 쉽게 치매의 전 단계인 경도인지장애를 선별하고자 여러 선별 검사지를 제작하여 경도인지장애 선별을 통한 치매를 예방하는 데 노력하는 중이다. 하지만 다양한 상황으로 각각의 효율성이 경도인지장애 선별에 대한 기대에 미치지 못하고 있다. 그리하여 본 연구는 기존에 개발된 경도인지장애 선별지 들을 비교 분석 및 코로나 상황에 적합하게 비대면 방식으로 경도인지장애 선별이 가능하도록 보다 효율적으로 개선하였으며 이를 IoT 기기에 접목하였다. 또한 IoT 기기는 어르신들의 경도인지장애 선별검사에 대한 부담감을 줄이고자 친근한 인형 형태로 개발하였으며 상호작용을 위한 기능 제작을 통하여 마음 돌봄 서비스를 구현하였다.

• Journal of rehabilitation welfare engineering & assistive technology
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• 제9권2호
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• pp.105-113
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• 2015

The purpose of the study was to verify the clinical effect of Computer-based cognitive rehabilitation program for Children for recovering the visual perception and ADL ability in intellectual disability. For this purpose, 3 intellectual disabilities with visual perception and ADL disorders participated in a clinical experiment to verify the effect of Computer-based cognitive rehabilitation program. They all have 5 common conditions in intellectual disability for objective experimental result. All participant were evaluated with Korean-Development Test of Visual Perception-2(K-DTVP-2), Wee Functional Independence Measure(Wee-FIM) before and after the planned intervention sessions. All intervensions were intensively carried out for 20weeks, 1 time a week. The result were as follows. K-DTVP and Wee-FIM scores were improved significantly compared to pre-intervention. Further studies are needed to verify the effect on various group and lots of participants.

• Journal of the Korea Society of Computer and Information
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• 제27권11호
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• pp.89-98
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• 2022

Using the extended technology acceptance model, this study aims to quantitatively analyze the user experience with the . In the case of Perceived Usefulness and Perceived Ease of Use, only limited detailed factors have significant impacts on the degree of satisfaction. The degree of satisfaction has positive correlations with the degree of immersion and the variables of Behavioral Intention to Use Metaverse. Although sophisticatedly remediates using digital technology to provide visitors with the sameness of exhibits, exhibition circulation and interaction method, the metaverse exhibition does not acquire the same value of the exhibition. In conclusion, cannot replace , however, it has the potential to offer learning usefulness to visitors with low accessibility to the art museum.

• The Journal of the Convergence on Culture Technology
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• 제4권4호
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• pp.95-100
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• 2018

The purpose of this study was to investigate the effects of cognitive programs on cognitive function improvement in patients with mild dementia. The subjects were 30 patients with mild dementia. The subjects were applied the cognitive rehabilitation program three times a week for 6 weeks and analyzed the pre-experiment and post-experiment values through the Korean simplified mental state examination (MMSE-K). The results were as follows: The mean of test was increased and statistically significant. Thus, cognitive rehabilitation programs for patients with mild dementia are effective interventions to improve cognitive function in patients with dementia.

• Korean Journal of Psychosomatic Medicine
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• 제11권2호
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• pp.205-213
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• 2003

Objectives: The authors intended to evaluate long-term outcome of group cognitive behavioral therapy(GCBT) for panic disorder and examined the variables to predict high end-state functioning in 12 months follow-up. Methods: 236 patients meeting DSM-IV criteria for panic disorder were assessed by STAI, ASI, BDI, BSQ, PBQ, ACQ at pre & post treatment, and were asked about the frequency of panic attacks during recent one month. We executed stepwise discriminant analysis on the clinical variables at pre treatment assessment to find the variables for discriminating between high end-state function(HES) and low end-state function(LES). Results: After GCBT, 82.6% of panic patients maintained high end-state functioning at 12 months follow-up. The results of discriminant analysis showed that BDI and BSQ at pre treatment assessment were significant variables to predict end-state functioning at 12 months follow-up. The hit ratio of discriminant analysis was 69.2%. Conclusion: These results suggest that the therapeutic effect of GCBT can be maintained through 12 months. Especially, it is likely that patients who were less depressed and who had less experienced the fear of physical symptoms at pre-treatment can maintain HES.

• Therapeutic Science for Rehabilitation
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• 제8권4호
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• pp.41-51
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• 2019

Objective : The purpose of this study was to investigate the effects of virtual reality-based activities of daily living (ADL) training on ADL and rehabilitative motivation in patients with traumatic brain injury. Methods : This study was performed using a pre-post design with seven traumatically brain injured patients. Subjects were subjected to virtual reality-based ADL training for 30 minutes a day, 2 to 3 times a week for 4 weeks. Evaluation was conducted before and after the intervention using the Korean Modified Barthel Index (K-MBI), Cognitive Functional Independence Measure (C-FIM), and Volitional Questionnaire (VQ). Changes before and after intervention were analyzed by Wilcoxon signed-rank test, and correlations were analyzed using Spearman's coefficient. Results : After intervention, patients with traumatic brain injury showed significant improvements in K-MBI (p<.05). There was no significant change in total C-FIM score and VQ score (p>.05). Total C-FIM score correlated significantly with VQ score (p<.05, r=.755). The social cognition domain of C-FIM had a significant correlation with VQ score (p<.05, r=826). Conclusions : Virtual reality-based ADL training can improve ADL performance, but further research is needed to determine whether improvements in social cognition and rehabilitative motivation are possible.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제18권5호
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• pp.549-556
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• 2017

This study investigated the importance of social cognitive intervention and the cognitive rehabilitation intervention by comparing the difference and examining the relationship between neurological cognitive function and social cognitive function of stroke patients in the acute phase and chronic stroke before returning to the community. LOTCA, cartoon intention inference task, and social behavior sequence task were performed on 30 acute stroke inpatients and 30 chronic stroke patients from May 2015 to June 2016. A two sample t test was conducted to examine the differences between the groups. The Pearson's correlations test was performed to examine the correlation among the variables in each group. As a result, there were statistically significant differences between the neurological cognitive function and social cognitive function of acute stroke patients and chronic stroke patients who were undergoing rehabilitation training before returning to the community (p<0.05). A linear relationship was found between the thinking operation and social behavior sequence task in the acute stroke group (r=0.539, p<0.05). In the chronic stroke group, visual perception (r=0.530, p<0.05), visual motor organization (r=0.655, p<0.05) and thinking operation (r=0.534, p<0.05) were correlated with the cartoon intention inference task. In addition, the social behavior sequence task were correlated with visual organization (r=0.534, p<0.05) and thinking operation (r=0.764, p<0.05). As a result of multiple regression analysis, the neurological cognitive functions influencing the social cognitive function in the cartoon task was found to be the thinking operation (B = 0.431) in acute stroke patients and the thinking operation (B=0.272) and visuomotor organization (B = 0.218) in the case of chronic stroke. In addition, the results of the social behavior sequence task revealed the thinking operation (B=0.417) in the acute stroke patients, and thinking operation (B=0.267), visual motor organization(B=0.274) and visual perception(B=151) in chronic stroke patients to be significant. According to this result, there is a difference in the neurological and social cognitive levels between the two groups. Therefore, the social cognition is strongly related to the high level cognitive function as thinking operation of the neurological cognitive function. Therefore, in further research, it would be necessary to determine if there is a change in higher cognitive function in neurological cognitive function after applying a social cognition intervention program for stroke.

• Korean Journal of Biological Psychiatry
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• 제2권2호
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• pp.177-185
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• 1995

외상후 뇌손상은 대표적이며, 가장 중요한 신경정신계 질환의 하나이다. 더욱이 외상후 뇌손상 환자들은 각종의 사고 및 산업재해 등으로 인해 그 수가 급증하고 있으며, 특히 인지기능의 장애로 인한 다양한 기질성 정신장애로 고통을 겪게 된다. 따라서 외상후 뇌손상은 손상의 시점에서부터 정확하고 올바른 평가는 물론 손상후의 경과 및 치료대책의 수립에 있어서 체계적이며 종합적인 신경인지기능의 평가는 필수적이다. 왜냐하면 신경인지기능평가는 뇌의 손상부위와 이와 관련된 기능장애 및 행동의 변화에 대한 객관적인 자료를 제시해 주기 때문이다. 신경인지기능 평가의 영역은 지각, 운동기능은 물론 주요인지기능인 기억, 언어, 실행 및 감정조절능력에 이르기까지 다양하며, 외상후 뇌손상환자들은 손상부위 및 정도에 따라 신경인지기능의 장애를 초래하게 된다. 대표적인 신경인지기능평가 도구로는 KWIS, Halstead-Reitan, Luria-Nebraska batteries, 특히 전두엽기능검사인 Wisconsin Card Sorting Test (WCST)를 비롯하여, 현재는 PC/S Vienna Test System 및 Stim등의 각종 전산화 인지기능검사가 개발되어 임상에서 활발히 사용되고 있다. 즉 외상후 뇌손상환자를 위한 신경인지기능평가의 목적은 뇌손상과 관련된 신경인지기능장애를 정확히 평가하여, 환자 개개인에 적합한 인지재활치료 계획을 수립하는데 있다. 물론 여기에는 신경정신상태검사(neuropsychiatric mental status examination)를 통하여 외상 후 뇌손상의 경과 및 예후에 결정적인 영향을 미칠 수 있는 나이, 의식소실 및 외상후 기억 손상 시간의 정확한 측정은 물론 심리 사회 문화적인 상태와 두부외상전 환자의 지적수준 및 사회 적용기능이 함께 평가되어야 할 것이다.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제19권12호
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• pp.758-764
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• 2018

This study was performed to investigate the effects of Occupation based Reminiscence therapy on cognitive function, depression, and quality of life in elderly patients with mild dementia. Thirty-one elderly patients with mild dementia underwent Occupation based Reminiscence therapy for 40 minutes per session, once weekly, for 8 weeks. Montreal Cognitive Assessment Korean Version (MoCA-K), Short Form of Geriatric Depression Scale-Korean Version (SGDS-K), and Geriatric Quality of Life-Dementia (GQOL-D) were used to measure cognitive function, depression level, and quality of life, respectively. Mean MoCA-K score increased from $14.62{\pm}5.07$ before intervention to $16.88{\pm}4.55$ after intervention; mean SGDS-K score decreased from $7.28{\pm}4.28$ to $6.10{\pm}4.09$, and mean GQOL-D score increased from $26.05{\pm}5.45$ to $28.55{\pm}5.74$. Furthermore, these positive changes were all statistically significant. Based on the results of this study, it was concluded Occupation based Reminiscence therapy may positively affect cognitive function, depression, and quality of life in elderly patients with mild dementia.