• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.475-481
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• 2020

This study investigated the mental health factors of juveniles according to socio-demographic characteristics and mental health related characteristics using the Korea Youth Risk Behavior Web-Based Survey 2019 Data. The study subjects were total 57,303 students (middle school: 29,384, high school: 27,919). The data was analyzed with descriptive statistics, frequency analysis, χ²-tests and regression analysis using SPSS ver. 18.0. The findings revealed that socio-demographic characteristics (gender, residential area, residential type, economic status, school achievement) and mental health related characteristics (subjective assessment, stress cognition, overcoming fatigue through sleeping, experiencing sadness and despair, suicidal ideation, suicidal planning, suicidal attempts, experience of hospital care for violence, experience of smoking, drinking, sexual relations and/or habitual drug use, internet use except for study) were factors that influenced factors related to the mental health of juveniles (p<0.05). The mental health of juveniles was closely related with health behaviors. This study could be used as a tool for the development and establishment of juveniles' health promotion and prevention strategies in the future.

• Journal of Life Science
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• v.32 no.10
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• pp.812-820
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• 2022

Depression is a psychiatric disorder characterized by depressed mood, anhedonia, fatigue, and altered cognitive function, leading to a decline in daily functioning. In addition, depression is a serious and common mental illness not only in an individual's life but also in society, so it must be actively treated. Autophagy is involved in the pathophysiological mechanism of mental illness. According to a recent study, it is known that autophagy-induced apoptosis affects neuroplasticity and causes depression and that antidepressants regulate autophagy. Autophagy is a catabolic process that degradation and removes unnecessary organelles or proteins through a lysosome. And, it is essential for maintaining cellular homeostasis. Autophagy is activated in stress conditions, and depression is a stress-related disease. Stress causes damage to cellular homeostasis. Recently, although the role of autophagy mechanisms in neurons has been investigated, the autophagy of depression has not been fully studied. This review highlights the new evidence for the involvement of autophagy in the pathophysiological mechanisms and treatment of depression. To highlight the evidence, we present results from clinical and preclinical studies showing that autophagy is associated with depression. Understanding the relevance of autophagy to depression and the limitations of research suggest that autophagy regulation may provide a new direction for antidepressant development.

• Sleep Medicine and Psychophysiology
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• v.24 no.1
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• pp.38-45
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• 2017

Objectives: Sleep disturbance is a very rapidly growing disease with aging. The purpose of this study was to investigate the prevalence of sleep disturbances and its predictive factors in a three-year cohort study of people aged 60 years and over in Korea. Methods: In 2012 and 2014, we obtained data from a survey of the Korean Social Life, Health, and Aging Project. We asked participants if they had been diagnosed with stroke, myocardial infarction, angina pectoris, arthritis, pulmonary tuberculosis, asthma, cataract, glaucoma, hepatitis B, urinary incontinence, prostate hypertrophy, cancer, osteoporosis, hypertension, diabetes, hyperlipidemia, or metabolic syndrome. Cognitive function was assessed using the Mini-Mental State Examination for dementia screening in 2012, and depression was assessed using the Center for Epidemiologic Studies Depression Scale in 2012 and 2014. In 2015, a structured clinical interview for Axis I psychiatric disorders was administered to 235 people, and sleep disturbance was assessed using the Pittsburgh Sleep Quality Index. The perceived stress scale and the State-trait Anger Expression Inventory were also administered. Logistic regression analysis was used to predict sleep disturbance by gender, age, education, depression score, number of coexisting diseases in 2012 and 2014, current anger score, and perceived stress score. Results: Twenty-seven percent of the participants had sleep disturbances. Logistic regression analysis showed that the number of medical diseases three years ago, the depression score one year ago, and the current perceived stress significantly predicted sleep disturbances. Conclusion: Comorbid medical disease three years previous and depressive symptoms evaluated one year previous were predictive of current sleep disturbances. Further studies are needed to determine whether treatment of medical disease and depressive symptoms can improve sleep disturbances.

• Journal of Digital Convergence
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• v.13 no.8
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• pp.419-429
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• 2015

We investigate how the regional prevalence of hyperlipidemia is affected by health-related and socioeconomic factors with a special emphasis on geographic variations. We focus on the likelihood of hyperlipidemia as function of various region-specific attributes. We analysis a data set at the level of 249 small administrative districts collected from 2012 Korean Community Health Survey by Korea Centers for Disease Control and Prevention. To estimate, we use several methods including correlation analysis, multiple regression and decision tree model. We find that the average prevalence of hyperlipidemia in 249 small districts is 9.6% and its coefficient of variation is 28.3%. Prevalence of hyperlipidemia in continental and capital regions is higher than in southeast coastal regions. Further findings using decision tree model suggest that variations of hyperlipidemia prevalence between regions is more likely to be associated with rate of employee, level of stress, prevalence of hypertension, angina pectoris, and osteoarthritis in their regions.

• The Journal of the Convergence on Culture Technology
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• v.5 no.1
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• pp.153-167
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• 2019

Purpose: The aim of this study was to examine factors influencing health-related quality of life in middle and old adult one-person households. Method: This study carried out secondary analysis using the data from the $7^{th}$ Korean National Health and Nutrition Examination Survey. Subject samples who were selected are 497 middle and old adult one-person households over 40 years. Data were analyzed using descriptive statistics, simple and multiple regression techniques with the SPSS/WIN 24 program. Result: Factors influencing health-related quality of life in middle adult one-person households were activity limitation, depression, exercise, smoking habits with 57% prediction. In male old adult one-person households they were subjective health, metabolic syndrome, activity limitation, perceived stress with 44.8% prediction and in female old adult one-person households they were subjective health, activity limitation, home income with 35.9% prediction. Conclusion: Therefore, to improve their health-related quality of life it needs to develop & to apply national and local promotion policy and intervention program on health-related quality of life of middle and old adult one-person households.

• Journal of Industrial Convergence
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• v.20 no.10
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• pp.61-69
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• 2022

Posttraumatic growth literature has been rapidly expanding in multiple academic disciplines. Purpose of this study is to examine the knowledge structure of posttraumatic growth utilizing a network analysis. Papers published between 1996 and 2018 were searched on the Web of Science, focusing on terms related to posttraumatic growth. One thousand six-hundred and fifty-nine keywords were published 6,343 times in 1,780 papers; thus, a total of 322 keywords (5,195 appearances) were selected for the final analysis. The network analysis and network visualization tool used were NodeXL and PFnet, respectively. The keywords which appeared the most frequently were "Posttraumatic growth," followed by "Posttraumatic Stress Disease," "Cancer," and "Trauma." A total of 322 nodes have been reduced to 175 nodes and divided into a total of five groups. The five groups were "Posttraumatic Growth in Cancer, Chronic/Serious Illness, and Disability," "Posttraumatic Growth-related Psychological Variables and Psychotherapy," "Posttraumatic Growth in the Context of Death," "Cognitive Mechanisms of Posttraumatic Growth," and "Vicarious Posttraumatic Growth." This study provides a systematic overview on the knowledge structure of posttraumatic growth by quantitatively network analysis.

• Korean Journal of Culture and Social Issue
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• v.25 no.1
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• pp.55-77
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• 2019

Negative experience related to work-family multiple roles has been associated with internalizing problems in mothers. In particular, employed mothers with preschool children report high degree of stress. As such, the need to examine potential factors that may explain and alleviate such difficulties has been emphasized. The purpose of this study was thus to examine the mediating effect of sociotropy on the relationship between negative work-family multiple roles and internalizing problems in employed mothers with preschool children. The Negative Experience of Work-Family Multiple Roles Scale, Adult Self Report (ASR) Scale, and Personal Style Inventory-II (PSI-II), were completed by 208 employed mothers with preschool children through an online survey. The results indicated that the direct effect of negative experience of work-family multiple roles on internalizing problems was statistically significant and the indirect effect of sociotropy in this relationship was significant. These findings suggest that sociotropy in employed mothers may indirectly explain internalizing problems related to multiple roles. The implications of sociotropy in negative experience of work-family multiple roles and internalizing problems are discussed.

• Cartoon and Animation Studies
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• s.36
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• pp.237-257
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• 2014

This study is the process of performing the interdisciplinary fusion study between multiple fields by identifying the status on the previous artistic education considering the brain scientific mechanism of image creativity and brain-based learning principles. In recent years, producing the educational methods of each field as the fusion study activities are emerging as the trend and thanks to such, the results of brain-based educational fusion studies are being presented for each field. It includes artistic fields such as music, art and dance. In other words, the perspective is that by understanding the operating principles of the brain while creativity and learning is taking place, when applying various principles that can develop the corresponding functions as a teaching method, it can effectively increase the artistic performance ability and creativity. Since the animation drawing should be able to intuitively recognize the elements of movement and produce the communication with the target beyond the delineative perspective of simply drawing the objects to look the same, it requires the development of systematic educational method including the methods of communication, elements of higher cognitive senses as well as the cognitive perspective of form implementation. Therefore, this study proposes a literature study results on the artistic education applied with brain-based principles in order to design the educational model considering the professional characteristics of animation drawing. Therefore, the overseas and domestic trends of the cases of brain-based artistic education were extracted and analyzed. In addition, the cases of artistic education studies applied with brain-based principles and study results from cases of drawing related education were analyzed. According to the analyzed results, the brain-based learning related to the drawing has shown a common effect of promoting the creativity and changes of positive emotion related to the observation, concentration and image expression through the training of the right brain. In addition, there was a case of overseas educational application through the brain wave training where the timing ability and artistic expression have shown an enhancement effect through the HRV training, SMR, Beta 1 and neuro feedback training that strengthens the alpha/seta wave and it was proposing that slow brain wave neuro feedback training contributes significantly in overcoming the stress and enhancing the creative artistic performance ability. The meaning of this study result is significant in the fact that it was the case that have shown the successful application of neuro feedback training in the environment of artistic live education beyond the range of laboratory but the use of the machine was shown to have limitations for being applied to the teaching methods so its significance can be found in providing the analytical foundation for applying and designing the brain-based learning principles for future animation drawing teaching methods.

• Journal of Korean Society of Neurocognitive Rehabilitation
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• v.10 no.2
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• pp.53-62
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• 2018

The purpose of this study was to propose an alternative for the eating habits of modern people and coping with the diseases. The purpose of this study was to apply the principles of eating habits of people living in Roma Linda to modern dietary life and to help healthy life and prevent disease. The period of this study was from May 1, 2016 to February 28, 2018. Literature search was conducted using Pubmed and Korean academic web sites. Based on the recognition of wrong eating habits, we classify and classify diseases according to eating habits. A total of more than 100 papers were selected and 60 papers and a database were prepared. People living in Roma Linda have eight health principles. The Roma Linda practiced balanced nutritional intake, sufficient exercise, adequate water intake, sunlight, temperance (abstinence from alcohol etc.), fresh air, adequate rest, and trust in eating habits. People living in Roma Linda have a high intake of vegetables, fruits and nuts. People living in Roma Linda are educated about nutrition, and among them, there is a low prevalence of coronary heart disease and cancer, because they mostly do not smoke or drink alcohol. Unhealthy eating habits and dietary behavior are associated with many diseases. Many chronic, degenerative diseases are due to bad eating habits and stress. If you take good food habits of people living in the Roma Linda area and practice it steadily, it will have a great effect on disease prevention.

• Journal of Life Science
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• v.15 no.6 s.73
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• pp.961-967
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• 2005

Macrophage migration inhibitory fartor (MIF), known as a cytokine, is a multifunctional protein that is ubiquitously expressed in a variety of cells and tissues; however, enzymatic function of MIF still remains elusive in cells. In this study, we assessed details of the tautomerase activity of MIF. We established rapid purification condition for MIF by using pGEX system and compared the L-dopachrome tautomerase activity of GST-MIF, tMIF, and MIF. The results show that GST (glutathione S-transferase)-epitope tag or N-terminal amino acids flanking the essential $P^{2}$ almost completely abrogated L-dopachrome tautomerase activity of MIF. Subsequently, to determine whether the N-terminal tags have effects on oligomerization of MIF, protein cross-linking products were analyzed on $15\%$ SDS-PACE. The result demonstrates that N-terminal tags are dispensable for the formation of MIF's homooligomers. Thus, the results imply that exposure of If containing hydrophobic pocket in the active site is critical for L-dopachrome tautomerase activity of MIF. In addition, our study suggest that the MIF's tautomerase activity might be influenced by interacting with cellular partners.