• Applied Biological Chemistry
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• v.43 no.4
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• pp.303-308
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• 2000

Male Sprague-Dawley rats received either a cholesterol diet (Control group) or cholesterol diets supplemented with the water-extracted of leaves from Morus alba (MA group) or Cudrania tricuspidata (CT group) at the level of 1% for 2 weeks. The concentration of serum triglyceride was significantly lower in the CT group and was also lower in the MA group than in the control group. The liver cholesterol concentration was significantly lower in the MA group than in the control group, but not significantly different between the CT group and the control group. The concentration of phospholipid in serum was an increasing tendency in the MA group and was a decreasing tendency in the CT group compared to that in the control group. Body weight gain, food intake, food efficiency, the concentrations of triglyceride and phospholipid in liver, and the total cholesterol, HDL-cholesterol and glucose in serum were not significantly different among dietary groups. These results suggest that the water-extracted from leaves of Morus alba and Cudrania tricuspidata exerts a hypotriglycerolemic effect in the cholesterol-fed rats.

• The Journal of Korean society of community based occupational therapy
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• v.3 no.2
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• pp.1-12
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• 2013

Objective : The objective of this study is to present basic data to find health care plans for the elderly by comparing time-management ability and ADL and identifying the relationships between groups with subjects of elderly people living alone and living with family in Daejeon Metropolitan City. Method : A total of 80 elders who lived alone or with family that were aged 65 or older were selected with MMSE-K, 40 people were selected as subjects for each group. For time-management ability, a questionnaire was used. ADL were assessed by using FIM. The study period was May to June 2013. Result : Comparison of scores for time-management ability and FIM of the elderly who live alone or living with family did not show any statistically significant difference. In comparison of detailed scores between groups, there were statistically significant differences between the two groups being social interaction, problem solving and memory in social cognition items among detailed items. Conclusion : Through this study, we understood that social cognitive function of the aged living alone who had less opportunity of interaction compared to that of the aged living with family was lowered. Based on this, development and study on various programs should be made with consideration of sociodemographic characteristics of the elderly within community-based occupational therapy in the future.

• The Korean Journal of Food And Nutrition
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• v.16 no.2
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• pp.146-151
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• 2003

Chinese medical materials of Astragalas manbranaceus Bunge, Angelica gigas Nakai, Cnidium officinale, Glycyrrhiza uralensis Fisch, Lycium Chinese Mill were mixed, mixing ratio was 28:20: 18:18:16(w/w). Yield and concentration of extract obtained through extraction- concentration process of the mixed Chinese medical materials were 37.28%(w/w) and 50Brix, respectively. Animal feed(AF) used for animal test was manufactured from both mixing of general AF and this extract(0∼ 5%, w/w) and freeze dried. After the male rats were fed experimental diets in order to test during 4 weeks, the results of plasma TG, total cholesterol, phospholipid content changes and plasma, pancreas and femur insulin concentration changes were followed. The more the amount of treatment of Chinese medical material extract are, the higher the effect of concentration decline are in plasma lipid concentration. And at 3% treatment plasma TG, total cholesterol and phospholipid contents are decreased respectively 8.62%, 2.81% and 2.11%. Plasma glucose concentration has also similar effect that those things are decreased at 3% treatment. Insulin concentration of plasma, pancreas and femur are difficult to prove the effects due to respective increase and decrease. We guess that these results comes from not experimenting intentioned rat of diabetes mellitus but normal rat.

• Journal of Music and Human Behavior
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• v.12 no.1
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• pp.1-21
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• 2015

This study examined the effects of a tablet PC-based music-making program on the executive function of adolescents with intellectual disabilities. Four adolescents with intellectual disabilities participated in this program. Each participant received 45-minute individual sessions twice a week for a total of 16 sessions. The music-making program was designed in the sequence of planning; learning table PC operations; exploring musical elements; making rhythm, melody, and lyrics; composing loop sections; and presentation of the completed music. The Stroop test, Children's Color Trails Test, and Digit Span and Letter-Number sequencing tests were measured at pretest, midtest, and posttest in order to examine changes in executive function. The participants showed increased scores on all three tests. The participants' attention span also increased and their attempts to correct errors during tasks occurred more frequently at posttest. This study supports the effects of the technology-based program on the executive function of adolescents with intellectual disabilities and presents its expanded applicability for adolescents who show low cognitive function and limited motivation for cognitive engagement.

• Korean Journal of Plant Resources
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• v.26 no.4
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• pp.417-425
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• 2013

The aim of this study was to examine improving effect of Platycodon extracts (PE) and/or Platycodon extracts jelly (PEJ) on cognitive impairment in vitro and in vivo. PC12 (Pheochromocytoma) cells were pretreated with PE for 1hr and than incubated with $50{\mu}M$ amyloid ${\beta}(A{\beta})_{25-35}$ for additional 48hr. Cell viability was assessed by WST-1. Animals for Morris water test and passive avoidance test were divided into normal, control and two Platycodon extracts treated groups that were named Normal (n=7), Control (0 mg/kg, n=7), PE (300 mg/kg, n=7), PEJ (10 g/kg, n=7). Cognitive impairment was induced by scopolamine (1 mg/kg/body weight, i.p.) in the three experimental groups but not the normal group. Pretretment of PE (0.01-1 mg/mL) were not induced cytotoxicity but observed in high dose-treated group (5 and 10 mg/mL) in PC12 cells. Protective effects of PE against $A{\beta}$-induced cytotoxicity were increased in dose dependent manner in PC12 cells. Administration of PE and PEJ were significantly reduced escape latency time on Morris water maze test and passive avoidance test in copolamine-induced cognitive impairment animal model. These results suggest that Platycodon extracts and its related product available to ameliorative purpose for cognitive ability impairments.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.6
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• pp.1220-1226
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• 2001

This study was conducted to investigate the effect of water-soluble extract from roasted chicory on the lipid metabolism and oxidative stress in male Sprague-Dawley rats. The experimental groups were divided into three groups ; the normal group, the cholesterol group and the chicory group. Roasted chicory extract was supplemented at 5.0% (w/w) level in the cholesterol diet. Concentration of total cholesterol in serum was significantly higher in the cholesterol group than in the normal group, but this increase in the cholesterol group was significantly decreased by the cholesterol diet supplemented with chicory extract. Concentration of HDL-cholesterol in serum was significantly lower in the cholesterol group than in the normal group, but this decrease in the cholesterol group tended to increase in the chicory group. However, concentrations of triglyceride, phospholipid and nonesterified fatty acid in serum were not significantly different among the groups. Concentrations of triglyceride and cholesterol in liver were significantly higher in the cholesterol and chicory groups than in the normal group. Feces weight and the excretion of cholesterol and bile acid into feces were significantly higher in the chicory group than in other groups. Concentrations of thiobarbituric acid reactive substances (TBARS) in homogenates and microsomal fractions of liver were not significantly different among the groups. On the other hand, concentration of 8-hydroxydeoxyguanosine (8-OHdG) as an useful marker of oxidative stress in urine was lower in the chicory group than in other groups. Concentration of serum glucose was signnificantly lower in the cholesterol group than in the normal group, but that of the chicory group was significantly higher than in the normal group. These results demonstrated that dietary chicory extract exerted the decreasing effect of cholesterol level and oxidative stress in cholesteral-fed rats.

• Journal of the Korean Society of Food Science and Nutrition
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• v.18 no.3
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• pp.338-347
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• 1989

This study aims at revealing the effect of ${\omega}-3$ and ${\omega}-6$ polyunsaturated fatty acids on serum and lipid metabolism of liver in rats. Various diets were fed to 5 groups of rats differently composed of red pepper oil with about 64 % of ${\omega}-6$ linoleic acid and perilla oil with 60% or so of ${\omega}-3$ linolenic acid : group 1, 10% perilla oil ; group 2, 7.5% perilla oil and 2.5% red pepper oil; group 3, 5% perilla oil and 5% red pepper oil ; group 4, 2.5% perilla oil and 7.5% red pepper oil; group 5, 10% red pepper oil. The following shows the results. 1. As for cholesterol concentration in serum, group 1 was significantly lower than groups 4 and 5. 2. HDL-cholesterol concentration tended to grow gradually with the increase of ${\omega}-6$ linoleic acid and to decrease with the increase of ${\omega}-3$ linolenic acid. 3. Group 5 was the highest in HDL concentration of cholesterol. 4. About concentration of triglyceride and phospholipid in serum, group 2 was significantly lower than group 4. 5. In cholesterol level of liver, group 5 was the highest and groups 2, 3 and 4 were relatively lower. 6. Triglyceride concentration of liver was higher than others in groups 1 and 5.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.8
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• pp.210-220
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• 2017

This study investigated the effect of social support (MOS-SSS), and physical (ADL, IADL) and mental (CES-D, MMSE-K) function on the quality of life (WHOQOL- BREF) among the elderly at care facilities. The survey respondents were 524 elderly aged 65 and older living in 15 care facilities located in D city. Data were collected through a personal interview conducted by interviewers who visited each care facility from November 2015 to January 2016. As a result, the quality of life was significantly lower in the elderly group with lower social support, with dysfunction in ADL and IADL than in the normal range group, with depression and cognitive impairment group than in the normal range group. The quality of life had a significant positive correlation with social support, ADL, IADL and cognitive impairment, but a significant negative correlation with depression. According to the results of covariance structure analysis, physical function had a greater impact on the quality of life than mental function or social support. Lower quality of life was associated with lower physical and mental function and lower social support. Therefore, concrete measures need to be devised to enhance physical function in order to improve the quality of life among the elderly in care facilities.

• Journal of KIISE:Information Networking
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• v.37 no.5
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• pp.363-373
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• 2010

The existing QoS mechanisms for video streaming are short of the consideration for various user environments and the characteristic of streaming applying programs. In order to overwhelm this problem, studies on the video streaming protocols exploiting scalable video coding (SVC), which provide spatial, temporal, and qualitative scalability in video coding, are progressing actively. However, these protocols also have the problem to deepen network congestion situation, and to lower fairness between other traffics, as they are not equipped with congestion control mechanisms. SVC based streaming protocols also have the problem to overlook the property of videos encoded in SVC, as the protocols transmit the streaming simply by extracting the bitstream which has the maximum bit rate within available bandwidth of a network. To solve these problems, this study suggests TCP-friendly network adaptive SVC streaming(T-NASS) protocol which considers both network status and SVC bitstream property. T-NASS protocol extracts the optimal SVC bitstream by calculating TCP-friendly transmission rate, and by perceiving the network status on the basis of packet loss rate and explicit congestion notification(ECN). Through the performance estimation using an ns-2 network simulator, this study identified T-NASS protocol extracts the optimal bitstream as it uses TCP-friendly transmission property and perceives the network status, and also identified the video image quality transmitted through T-NASS protocol is improved.

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.2
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• pp.294-299
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• 2000

The effects of hot water soluble polysaccharides extract(PS) of Lentinus edodes on the lipid components in the liver and plasma of the rats fed the butter yellow were investigated. Twenty four rats were divided into four groups and fed with the diet containing 15% casein, 30% sucrose and 10% soybean oil (basal diet; NO group), supplemented with butter yellow (BO group) or/and PS (NP, BP group). The contents of triglyceride and phospholipid in liver were significantly lower in BP group than BO group but the content of total lipid and total cholesterol were not significant difference between BO and BP. The concentrations of total cholesterol and triglyceride of plasma were significantly lower in BP than BO. AS the results PS of Lentinus edodes prevent the triglyceride and cholesterol rise and then improve the lipid metabolism of rats fed the butter yeollow.