• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.601-606
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• 2023

The edible sweetener aspartame is formed from the synthesis of asparagine, one of the amino acids, and phenylalanine. It is a protein ingredient that produces sweetness 200 times higher than sucrose, and is used as a diet product because it is a substance that can replace sugar. Although the effects on animals and humans have been well studied, no studies have been conducted on plant metabolism. In this study, the effect of aspartame metabolism was tested using germinated onion, bean sprouts, and Kalanchoe. The three types of plants with germinated roots showed rapid growth in the early stage of treatment with 1mM aspartame, and showed a nutrient supply effect due to the effect of amino acids, which are constituents. However, when treated for 4 weeks, symptoms similar to lateral roots appear in the form of lignification in onions, the effect of quickly withering is seen in bean sprouts, and senescence of roots appears in 12-week-old Kalanchoe. All of them show accelerated aging after the growth phase. This shows that, among the two amino acids, asparagine is related to auxin generation that induces rapid growth, and it is thought to be the result of lignification due to the effect of phenylalanine.

• Journal of Conservation Science
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• v.33 no.2
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• pp.121-130
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• 2017

The currently used wax agents for preserving outdoor metal structures, despite their advantages, have disadvantages such as low endurance and reliability. These wax agents are easily damaged by acid rain, dust, moisture in the air, yellow dust, and air pollutants, resulting in corrosion within a short period after the initial conservation treatment. In addition, aged wax can also exhibit changes in the color or gloss, and also give a sense of difference in the surface. Given these existing problems, it is necessary to develop improved materials for metal preservation. Therefore, this study analyzed the characteristics and applications of the existing wax coating agents in order to identify their disadvantages and to develop a better material for metal preservation. In this regard, this study developed a perilla oil based compound wax and conducted experiments to test its endurance. The new compound wax agent was exposed to outdoor and acid rain conditions: it showed four times and 1.5 times the endurance of the existing wax agents in outdoor and acid rain conditions, respectively. In addition, the new agent seems to be more durable and protective as evidenced by the chromaticity, polish maintenance, and contact angle results. Further, although it is 1.3-1.8 times thicker than the existing agents, the new agent shows a more even surface. Based on these findings, it can be concluded that the new compound wax agent based on perilla oil is a better alternative to the existing was coating agents.

• Journal of Life Science
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• v.33 no.9
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• pp.730-735
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• 2023

In the past decade, numerous studies have been carried out to quantify aging with the help of artificial intelligence. Using DNA methylation data, various models have been developed; these are commonly called epigenetic clocks. Epigenetic age acceleration is usually associated with disease conditions. Schizophrenia is a mental illness associated with severe mental and physical stress. This disease leads to high mortality and morbidity rates in young people compared with other psychological disorders. In the past, the research community considered this disease to be related to the accelerated aging hypothesis. In the current study, we wanted to investigate the epigenetic age acceleration changes in schizophrenia patients to obtain epigenetic insights into the disease. To measure the epigenetic age acceleration, we used two different DNA methylation clock models, namely, Horvath clock and Epi clock, as these are pan-tissue models. We utilized 450k array data compatible with both clocks. We found a slower epigenetic acceleration in the patients' samples when we used the Epi clock. We further analyzed the differentially methylated CpG sites between the control and cases and performed pathway enrichment analysis. We found that most of the CpGs are involved in neuronal processes.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.05a
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• pp.535-538
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• 2022

근감소증은 영양부족, 운동량 감소 그리고 노화 등으로 정상적인 근육의 양과 근력 및 근 기능이 감소하는 질환을 말한다. 근감소증은 보편적으로 유럽 근감소증 실무그룹분석(EWGSOP)에서 정의한 측정 방법을 따른다. 본 논문에서는 근감소증 진단을 위한 영상 분할 모델을 개발하고 외부검증하는 방법에 대해서 제안한다. 우리는 CT 영상에서 L3 영역을 선별하여 자동으로 근육, 피하지방, 내장지방을 분할할 수 있는 인공지능 모델을 U-Net을 사용하여 개발하였다. 또한 모델의 성능을 평가하기 위해서 분할영역의 IOU(Intersection over Union)를 계산하여 내부검증을 진행하였으며, 타 병원의 데이터를 이용하여 같은 방법으로 외부검증을 진행한 결과를 보인다. 검증 결과를 토대로 문제점과 해결방안에 대해서 고찰하고 보완하고자 했다.

• Korean Journal of Plant Resources
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• v.22 no.5
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• pp.467-472
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• 2009

This study was conducted to break down the self-incompatibility of Astragalus membranaceus Bunge by old-flower pollination, NaCl and $CO_2$ treatment. The old-flower pollination in green house produced fertilization during the 1st and 2nd day after flowering from early September to early October, but almost no fertilization in late August. The most successful pollination occurred in late September at the 1st day after flowering when pod setting was 33.3% and that of seed set was about 86.2%. The old-flower pollination in field showed pod setting for the control group from late August to early October, but no seed set except the days of mid-September and late September. The most successful pollination occurred in late September during the 2nd day of flowering when the percentage of pod setting was 39% and that of seed set was 94.9%. The wrapping in field set pods from late August to early October, but did not set seeds except in mid and end of September. The percentage of pods was 39% and percentage of seeds was 94.9% about flowering after first day in end of September. by field culture. The best result from NaCl treatment was achieved when 1% NaCl treatment in green house produced 21.3% of pod setting in early October and 66.7% of seed set in late September. In field, NaCl 5% treatment produced best result with 7.3% of pod setting and 90.9% of seed set in mid-September. No differences were observed between the $CO_2$ 700ppm treatment and the control group.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.4
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• pp.321-327
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• 2017

This study was carried out to develop a stable plant-derived natural sunscreen (BHC-S) that replaces the artificially synthesized organic sunscreen agents. The natural sunscreen (BHC-S), which is composed of peanut extract, Centella asiatica extract, and Ecklonia stolonifera extract, has the same level of ultraviolet shielding effect as PARSOL MCX-XR (OMC), which is a synthetic sunscreen. and has safety against skin. MultiFunctional effect such as and anti-wrinkle improvement. Thus, it can be used as raw material for natural cosmetics for ultraviolet ray blocking, and anti-aging.

• Proceedings of the KIEE Conference
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• 2006.07e
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• pp.57-58
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• 2006

과거 2003년 북미 대 정전 이후 전력기기의 사고 발생 후 얼마나 빨리 사고를 제거하고 피해가 적도록 신속하게 복구하는 개념에서 사고이전에 사고를 미연에 방지하는 예방개념으로 관심이 높아지고 있다. 전력기기를 사고로부터 보호하는 보호기기도 중요하지만 사고이전의 상태를 감시하여 미연에 사고를 방지할 수 있도록 하는 예방진단시스템의 중요성도 높아지고 있다. 이렇듯 관심이 높아짐에 따라 각종 진단알고리즘의 개발이 신속히 이루어지고 있다. 보호기기처럼 어떤 설정된 정정 값 이상의 값이 입력되면 보호동작을 수행하는 단순 동작과는 달리 예방진단 시스템은 입력되는 신호의 패턴을 인식하여 열화/노화 등의 진행상황 및 정비조치에 대한 정보를 만들므로 인공지능적인 요소가 많이 적용되고 있다. 따라서 각종 Fuzzy, Neural Network, Expert 등 각종 판단 알고리즘과 패턴을 인식하는 확률통계, 프랙탈 기하학 등이 적용되고 있다. 모두가 틀리다는 것은 아니지만 보다 정확한 예방진단을 위해 각종 알고리즘이 추가 및 수정이 자주이루어지고 있는 실정이다. 그러나 새로운 알고리즘을 적용하기 위해서 기 개발되어 운영 중이거나 설치된 예방진단시스템을 멈추고 전반적으로 수정을 수행하는 것은 감시진단시스템의 본래 모습을 무시하는 행동이라고 할 수 있다. 본 연구에서는 이런 문제를 해결하기 위하여 온라인 상태에서 장비를 감시하는 예방진단 시스템의 알고리즘 변형 시 시스템의 운영이 문제되지 않도록하는 다이나믹 인터페이스를 개발하였다.

• The Journal of the Korea Contents Association
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• v.22 no.7
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• pp.46-54
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• 2022

The existing methods for determining influence in social networks do not accurately determine the influence of users because they do not delete or update existing relationships before they stop in the face of an increasing number of inactive users on social networks. In this paper, we propose a user influence detremination method using the temporal k-shell decomposition technique based on the creation date of users of social networks. To solve the problem of increasing influence of old users in social networks, we apply k-shell decomposition and age-specific order centrality as attenuation coefficients due to aging in neighbors. The age-decaying k-shell decomposition and age-specific order centrality are searched for influential users at the present time by applying the attenuation coefficient and age-dependent weights. Various performance evaluations are performed to show the superiority of the proposed method.

• Microbiology and Biotechnology Letters
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• v.30 no.4
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• pp.359-366
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• 2002

Bacillus polyfermenticus SCD which is commonly called as Bisroot strain is being used for functional foods through the treatment of long-term intestinal disorders, since the live strains in the form of active endospores can successfully reach the target intestine in humans. The cells of B. polyfermenticus SCD were treated for 4h in artificial gastric juice (pH 2.0,3.0) and bile acid. Final viability of the strain in artificial gastric Juice (pH 2.0, 3.0) is reached to 62.8% and 81.2% respectively B. polyfermenticus SCD is resistant to antibiotics such as streptomycin, rifampicin, nystatin and ampicilin. B. polyfermenticus SCD is well known supplies the nutrients by synthesizing vitamin $B_1$, $B_2$, C and K. B. polyfermenticus SCD produces various digestive enzymes and the enzymes enable to completely digest diets in our body. Above all, $\alpha$-amylase and pretense activities are very higher than B. subtilis KCTC 1020, about two fold and twenty five fold respectively. B. polyfermenticus SCD is very stable during long-term storage period in phosphate buffers of wide-range pH, solutions of various concentrations of sodium chloride, 5% glucose solution and water.

• Journal of Conservation Science
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• v.26 no.1
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• pp.61-67
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• 2010

After selecting five types of adhesive epoxy resin for metallic cultural assets such as $Araldite^{(R)}$ rapid type, $Devcon^{(R)}$, $Araldite^{(R)}$ SV427+HV427, $CDK^{(R)}$520, $Araldite^{(R)}$ AW106+HV953 which had already been studied, this paper approached more closely the problem of yellowing and the signal of aging with time passing by connecting the problems with the safety of metallic cultural assets. The change of physical properties according to the change of state of epoxy adhesives was investigated through the change of flexural strength and the change of surface hardness by artificially providing the possible environmental change factors such as ultra-violet ray, and acid base, and how the epoxy chemically changes in its ingredients by the environment was analyzed through FT-IR. As a result of the experiment, for the most part of adhesives brought about the physical change of flexural strength, the change of surface hardness, and the chemical change of chemical ingredients as the product of alcohol, which were respectively different according to the time of ultraviolet irradiation, and acid base change. Under most of the conditions, SV427+HV427 and $CDK^{(R)}$520 were fairly stabilized under each condition of weatherability, but it seems that they should be refrained from being applied in case that the area to restore is thin and wide because the degree of flexural strength of themselves is low. Also, it is found that the preservation environment is very important not only for artifacts but also for the preservation of resins sused for preservation treatment.