• Title/Summary/Keyword: 인간 배아줄기세포

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Clinical Effect through Histological Characteristics of Focal Ischemia Region (뇌허혈성 부위의 조직학적 특성을 통한 임상적 영향)

  • Lee, Tae-Hoon
    • Journal of Industrial Convergence
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    • v.17 no.4
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    • pp.39-43
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    • 2019
  • Mouse embryonic stem cell could show an substitutional materials of cells of neuron differentiation, positively increasing their effectiveness in the treatment of nervous symptom. We examined that mouse embryonic stem cells (mESCs) can be induced to undergo neuronal differentiation. After neuronal induction, the phenotype of mESCs changed towards neuronal morphology and mESCs were injected into the lateral ventricle of the experimental animal brain. Transplanted cells migrated to various parts of the brain and ischemic brain injury by middle cerebral artery occlusion (MCAO) increased their migration to the injured cortex. Intracerebral grafting of mESCs mostly improve sensory and motor nervous system of neurological injury in focal cerebral rats.