• Title/Summary/Keyword: 이선형 모델

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Analysis of Interactions in Multiple Genes using IFSA(Independent Feature Subspace Analysis) (IFSA 알고리즘을 이용한 유전자 상호 관계 분석)

  • Kim, Hye-Jin;Choi, Seung-Jin;Bang, Sung-Yang
    • Journal of KIISE:Computer Systems and Theory
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    • v.33 no.3
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    • pp.157-165
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    • 2006
  • The change of external/internal factors of the cell rquires specific biological functions to maintain life. Such functions encourage particular genes to jnteract/regulate each other in multiple ways. Accordingly, we applied a linear decomposition model IFSA, which derives hidden variables, called the 'expression mode' that corresponds to the functions. To interpret gene interaction/regulation, we used a cross-correlation method given an expression mode. Linear decomposition models such as principal component analysis (PCA) and independent component analysis (ICA) were shown to be useful in analyzing high dimensional DNA microarray data, compared to clustering methods. These methods assume that gene expression is controlled by a linear combination of uncorrelated/indepdendent latent variables. However these methods have some difficulty in grouping similar patterns which are slightly time-delayed or asymmetric since only exactly matched Patterns are considered. In order to overcome this, we employ the (IFSA) method of [1] to locate phase- and shut-invariant features. Membership scoring functions play an important role to classify genes since linear decomposition models basically aim at data reduction not but at grouping data. We address a new function essential to the IFSA method. In this paper we stress that IFSA is useful in grouping functionally-related genes in the presence of time-shift and expression phase variance. Ultimately, we propose a new approach to investigate the multiple interaction information of genes.

The Change in Geotechnical Properties of Clay Liner and the Contamination Behavior of Groundwater Due to Contaminant (오염물질에 의한 점토 차수재의 역학적 특성변화 및 지하수 오염거동)

  • Ha, Kwang-Hyun;Lee, Sang-Eun;Chung, Sung-Rae;Chun, Byung-Sik
    • Journal of Soil and Groundwater Environment
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    • v.13 no.1
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    • pp.13-23
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    • 2008
  • The triaxial compression tests and consolidation tests using NaCl solution and leachates as substitute pore (or saturated) water in samples were carried out to find out the behavior characteristics of strength, deformation and permeability coefficient of contaminated clay. Also, the chemical property analysis on the clay samples using scanning electron microscope and energy dispersive x-ray spectrometer were involved. The magnitudes of composition ratio were shown in the order of O, C, Si, Al, and Fe as a result of chemical composition analysis for clay samples. Besides, as the results of triaxial compression tests and consolidation tests, the shear strength, compression and permeability properties were increased with increasing in the concentration of contaminant (NaCl). It may be considered that these circumstances be caused by the changes of soil structure to flocculent structure due to the decrease in the thickness of diffuse double layer with increasing in the concentration of electrolyte. MT3D model was also using to grasp the procedures that the groundwater may be contaminated by the leachates permeated through the clay liner. The results of contaminant transport analysis showed a tendency that the predicted concentration of groundwater was higher with increasing in the initial concentration of $Cl^-$ ion and increased as a nonlinear curves with time. The transportation distance calculated by the use of regression equation between the distance from contaminant source and the concentration of $Cl^-$ ion was increased with increasing the initial concentration.

Evaluation of Robust Performance of Fuzzy Supervisory Control Technique (퍼지관리제어기법의 강인성능평가)

  • Ok, Seung-Yong;Park, Kwan-Soon;Koh, Hyun-Moo
    • Journal of the Earthquake Engineering Society of Korea
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    • v.9 no.5 s.45
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    • pp.41-52
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    • 2005
  • Using the variable control gain scheme on the basis of fuzzy-based decision-making process, Fuzzy supervisory control (FSC) technique exhibits better control performance than linear control technique with one static control gain. This paper demonstrates the effectiveness of the FSC technique by evaluating the robust performance of the FSC technique under the presence of uncertainties in the models and the excitations. Robust performance of the FSC system is compared with that of optimally designed LQG control system for the benchmark cable-stayed bridge presented by Dyke et al. Parameter studies on the robust performance evaluation are carried out by varying the stiffness of the bridge model as well as the magnitudes of several earthquakes with different frequency contents. From the comparative study of two control systems, FSC system shows the enhanced control performance against various magnitudes of several earthquakes while maintaining lower level of power required for controlling the bridge response. Especially, FSC system clearly guarantees the improved robust performance of the control system with stable reduction effects on the seismic responses and slight increases in total power and stroke for the control system, while LQG control system exhibits poor robust performance.

Estimation on the Radius of Maximum Wind Speed using RSMC Best Track Data (RSMC 최적경로 자료를 이용한 태풍의 최대풍속반경 산정)

  • Ko, Dong Hui;Jeong, Shin Taek;Cho, Hongyeon;Jun, Ki Cheon;Kim, Yoon Chil
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.25 no.5
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    • pp.291-300
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    • 2013
  • Typhoon simulation method is widely used to estimate sea surface wind speeds during the typhoon periods. Holland (1980) model has been regarded to provide relatively better results for observed wind data. JTWC or RSMC best track data are available for typhoon modeling, but these data show slightly different because the data generation process are different. In this paper, a Newton-Raphson method is used to solve the two nonlinear equations based on the Holland model that is formed by the two typhoon parameters, i.e. the longest radius of 25 m/s and 15 m/s wind speeds, respectively. The solution is the radius of maximum wind speed which is of importance for typhoon modeling. This method is based on the typhoon wind profile of JMA and it shows that Holland model appears to fit better the characteristics of typhoons on the temporal and spatial changes than that of the other models. In case of using RSMC best track data, the method suggested in this study shows better and more reasonable results for the estimation of radius of maximum wind speed because the consistency of the input data is assured.

Numerical Analysis of Nuclear-Power Plant Subjected to an Aircraft Impact using Parallel Processor (병렬프로세서를 이용한 원전 격납건물의 항공기 충돌해석)

  • Song, Yoo-Seob;Shin, Sang-Shup;Jung, Dong-Ho;Park, Tae-Hyo
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.24 no.6
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    • pp.715-722
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    • 2011
  • In this paper, the behavior of nuclear-power plant subjected to an aircraft impact is performed using the parallel analysis. In the erstwhile study of an aircraft impact to the nuclear-power plant, it has been used that the impact load is applied at the local area by using the impact load-time history function of Riera, and the target structures have been restricted to the simple RC(Reinforced Concrete) walls or RC buildings. However, in this paper, the analysis of an aircraft impact is performed by using a real aircraft model similar to the Boeing 767 and a fictitious nuclear-power plant similar to the real structure, and an aircraft model is verified by comparing the generated history of the aircraft crash against the rigid target with another history by using the Riera's function which is allowable in the impact evaluation guide, NEI07-13(2009). Also, in general, it is required too much time for the hypervelocity impact analysis due to the contact problems between two or more adjacent physical bodies and the high nonlinearity causing dynamic large deformation, so there is a limitation with a single CPU alone to deal with these problems effectively. Therefore, in this paper, Message-Passing MIMD type of parallel analysis is performed by using self-constructed Linux-Cluster system to improve the computational efficiency, and in order to evaluate the parallel performance, the four cases of analysis, i.e. plain concrete, reinforced concrete, reinforced concrete with bonded containment liner plate, steel-plate concrete structure, are performed and discussed.

Feature Ranking for Detection of Neuro-degeneration and Vascular Dementia in micro-Raman spectra of Platelet (특징 순위 방법을 이용한 혈소판 라만 스펙트럼에서 퇴행성 뇌신경질환과 혈관성 인지증 분류)

  • Park, Aa-Ron;Baek, Sung-June
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.48 no.4
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    • pp.21-26
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    • 2011
  • Feature ranking is useful to gain knowledge of data and identify relevant features. In this study, we proposed a use of feature ranking for classification of neuro-degeneration and vascular dementia in micro-Raman spectra of platelet. The entire region of the spectrum is divided into local region including several peaks, followed by Gaussian curve fitting method in the region to be modeled. Local minima select from the subregion and then remove the background based on the position by using interpolation method. After preprocessing steps, significant features were selected by feature ranking method to improve the classification accuracy and the computational complexity of classification system. PCA (principal component analysis) transform the selected features and the overall features that is used classification with the number of principal components. These were classified as MAP (maximum a posteriori) and it compared with classification result using overall features. In all experiments, the computational complexity of the classification system was remarkably reduced and the classification accuracy was partially increased. Particularly, the proposed method increased the classification accuracy in the experiment classifying the Parkinson's disease and normal with the average 1.7 %. From the result, it confirmed that proposed method could be efficiently used in the classification system of the neuro-degenerative disease and vascular dementia of platelet.

Strength and Lateral Torsional Behavior of Horizontally Curved Steel I-Girders Subjected to Equal End Moments (양단 균일 모멘트를 받는 수평곡선 I형 강재 거더의 횡-비틀림 거동 및 강도 산정 방안)

  • Lee, Keesei;Lee, Manseop;Choi, Junho;Kang, Youngjong
    • Journal of Korean Society of Steel Construction
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    • v.30 no.1
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    • pp.1-12
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    • 2018
  • A curved member should resist bending and torsional moments simultaneously even though the primary load is usually supposed to be gravitational load. The torsional moment causes complicate stress state and also can result in early yielding of material to reduce member strength. According to analysis results, the strength of a curved member that has 45 degrees of subtended angle could decrease more than 50% compare to straight girder. Nevertheless, there have been very few of researches related with ultimate strength of curved girders. In this study, various kinds of stiffness about bending, pure torsion and warping were considered with a number of models in order to verify the main factor that affects ultimate behavior of curved girder. Lateral and rotational displacement of curved member were introduced as lateral-torsional-vertical behavior and bending-torsional moment interaction curve was derived. Finally, a strength equation for ultimate moment of horizontally curved steel I-girders subjected to equal end moments based on the interaction curves. The equation could take account of the effect of curvature, unbraced length and sectional properties.

Low Conversion Loss 94 GHz MHEMT MIMIC Resistive Mixer (낮은 변환손실 특성의 94 GHz MHEMT MIMIC Resistive 믹서)

  • An Dan;Lee Bok-Hyung;Lim Byeong-Ok;Lee Mun-Kyo;Oh Jung-Hun;Baek Yong-Hyun;Kim Sung-Chan;Park Jung-Dong;Shin Dong-Hoon;Park Hyung-Moo;Park Hyun-Chang;Kim Sam-Dong;Rhee Jin-Koo
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.42 no.5 s.335
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    • pp.61-68
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    • 2005
  • In this paper, low conversion loss 94 GHz MIMIC resistive mixer was designed and fabricated. The $0.1{\mu}m$ InGaAs/InAlAs/GaAs Metamorphic HEMT, which is applicable to MIMIC's, was fabricated. The DC characteristics of MHEMT are 665 mA/mm of drain current density, 691 mS/mm of maximum transconductance. The current gain cut-off frequency(fT) is 189 GHz and the maximum oscillation frequency(fmax) is 334 GHz. A 94 GHz resistive mixer was fabricated using $0.1{\mu}m$ MHEMT MIMIC process. From the measurement, the conversion loss of the 94 GHz resistive mixer was 8.2 dB at an LO power of 10 dBm. P1 dB(1 dB compression point) of input and output were 9 dBm and 0 dBm, respectively. LO-RF isolations of resistive mixer was obtained 15.6 dB at 94.03 GHz. We obtained in this study a lower conversion loss compared to some other resistive mixers in W-band frequencies.

The Effect of Mild Tensile Reinforcement and Effective Prestress on the Flexural Performance of the Prestressed Lightweight Concrete Beams with Unbonded Tendons (비부착 프리스트레스트 경량 콘크리트 보의 휨 거동에 대한 부착 철근과 유효 프리스트레스의 영향)

  • Mun, Ju-Hyun;Yang, Keun-Hyeok;Byun, Hang-Yong
    • Journal of the Korea Concrete Institute
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    • v.23 no.5
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    • pp.617-626
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    • 2011
  • Seven post-tensioned lightweight concrete (LWC) beam specimens were tested under a symmetrical two-point top loading system. The parameters investigated were the amounts of mild longitudinal reinforcement and effective prestressing. The design compressive strength and dry density of the LWC tested were 30 MPa and 1,770 $kg/m^3$, respectively. Similar to post-tensioned normal weight concrete (NWC) beams, the crack propagation and stress increase of the unbonded tendons were significantly affected by the amounts of mild longitudinal reinforcement and effective prestressing. With the increase in the amounts of mild longitudinal reinforcement and effective prestressing, the serviceability and flexural capacity of the beams were enhanced whereas the stress increase in the unbonded tendons decreased. To control the crack width in post-tensioned LWC beams, a minimum amount of mild longitudinal reinforcement specified in ACI 318-08 provision is required. The flexural behavior of post-tensioned LWC beams and stress increase of the unbonded tendons could be rationally predicted by the proposed non-linear two-dimensional analysis. On the other hand, ACI 318-08 flexure provision was too conservative about the post-tensioned LWC beams.

Comparison of Performance of Restrainers of Steel Cables and Shape Memory Alloy Bars for Multiple-Span-Simply-Supported Bridges (다경간 단순지지 교량의 강케이블 및 형상기억합금 변위제어장치의 성능 비교)

  • Choi, Eun Soo;Kim, Lee Hyeon;Park, Joo Nam;Cho, Hyo Nam
    • Journal of Korean Society of Steel Construction
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    • v.19 no.6
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    • pp.587-597
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    • 2007
  • Steel restrainer cables for multiple frame bridges in California in the United States have been shown to be effective in preventing unseating at internal hinges during the past several earthquakes. Consequently, the steel-cable-restrainer is being tested for applications on multiple-span-simply-supported (MSSS) bridges in the mid-American region. In addition, shape memory alloy (SMA) bars in tension are being studied for the same application, multiple frame bridges, the developed seismic forces are transferred to piers through the restrainers. However, in MSSS bridges, the seismic forces are transferred to abutments by the restrainers. Therefore, the abutment' behavior should also be investigated. In this study, we assessed the seismic performance of the three types of restrainers, such as steel restrainer cables, SMA in tension, and SMA in bending for an MSSS bridge from moderate to strong ground motion, bending test of an SMA bar was conducted and its analytical model was determined for this study. Nonlinear time history analyses were conducted to assess the seismic responses of the as-built and the retrofitted bridges. All three types of restrainers reduced the hinge opening and the SMA in tension was the most effective of the three devices in preventing the unseating, all restrainers produced damage on the abutment from the pulling action of the MSSS bridge due to strong ground motions, was found that the retrofit of the abutment in the pulling action is required in the installation of restrainers in MSSS bridges.