• Title/Summary/Keyword: 융합 과학

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Comparison of Genome-wide Association Study (GWAS) Algorithms for Detecting Genetic Variants Associated with Growth Traits in Olive Flounder Paralichthys olivaceus (넙치(Paralichthys olivaceus)의 성장형질 연관 유전자 변이 탐색을 위한 전장유전체연관분석(GWAS) 알고리즘 비교 분석 연구)

  • Sangwon Yoon;Heegun Lee;Jong-Won Park;Minhwan Jeong;Dain Lee;Hyo Sun Jung;Julan Kim;Hye-Rim Yang;Seung Hwan Lee;Jeong-Ho Lee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.4
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    • pp.411-418
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    • 2023
  • Genome wide association studies (GWAS) identify genetic loci associated with quantitative traits in genomic selection. Although several studies have compared performance of various algorithms, no study compares them in olive flounder Paralichthys olivaceus. This study compared the GWAS results of four mixed linear model (MLM) algorithms and one Fixed and random model Circulating Probability Unification (FarmCPU) algorithm in olive flounder. Considering gender and genetic association matrices as fixed and random effects, the MLM had stable performance without inflation for λGC (genomic inflation factor) of -log10P. The FarmCPU algorithm had some appropriate λGC of -log10P, and an upward tail was identified in quantile-quantile plots. Therefore, the models were suitable for detecting genetic variants associated with olive flounder growth traits. Moreover, significant genotypes appeared several times at chromosome 22, around which quantitative trait loci are expected to exist. Finally, in both models, some of the most genetic variants were found in genes related to growth traits, confirming their reliability. These results will be helpful when applied to the genomic selection of olive flounder growth traits in the future.

Criminal Law Issues and Challenges Due to Changes in the Healthcare Paradigm (헬스케어 패러다임 변화에 따른 형사법적 쟁점과 과제)

  • Sun, JongSoo
    • The Korean Society of Law and Medicine
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    • v.24 no.1
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    • pp.43-65
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    • 2023
  • The healthcare industry is a digital healthcare that combines technology based on the 4th Industrial Revolution, dealing with information on individual health and medical care, and is a fusion of health care services and medical science and technology. It is questionable whether digital healthcare according to the paradigm change can be discussed by the concept of medical practice under the existing Medical Act. There is no clear definition of the concept of medical practice in the Medical Service Act, but the concept is established through precedents. In addition, under the Medical Service Act, the subject of medical practice is limited to medical personnel. However, digital healthcare sometimes diagnoses and treats diseases using digital technology by medical personnel. On the other hand, what is possible by non-medical personnel is digital healthcare. This is because digital healthcare is understood as a concept that includes health care such as exercise, eating habits, and weight control. For this reason, if the concept of medical practice under the "Medical Act" on digital healthcare is included, it is subject to criminal punishment for "unlicensed medical practice" prescribed in Article 27 of the "Medical Act". In the health and medical industry, digital transformation and convergence with information and communication technology are rapidly progressing. As a result, there is a need to newly define it as 'digitalized medical practice' or 'information and communication technology (ICT)-based medical practice' separately from existing medical practices. The concept of medical practice has variability, not a fixed and invariable concept. However, in response to this demand, it is not an infinite expansion of the concept of medical practice, but a request to reset its scope. Therefore, the concept of medical practice should be legislated by reflecting the demand of consumers for the medical service system.

A Study on Data Clustering of Light Buoy Using DBSCAN(I) (DBSCAN을 이용한 등부표 위치 데이터 Clustering 연구(I))

  • Gwang-Young Choi;So-Ra Kim;Sang-Won Park;Chae-Uk Song
    • Journal of Navigation and Port Research
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    • v.47 no.4
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    • pp.231-238
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    • 2023
  • The position of a light buoy is always flexible due to the influence of external forces such as tides and wind. The position can be checked through AIS (Automatic Identification System) or RTU (Remote Terminal Unit) for AtoN. As a result of analyzing the position data for the last five years (2017-2021) of a light buoy, the average position error was 15.4%. It is necessary to detect position error data and obtain refined position data to prevent navigation safety accidents and management. This study aimed to detect position error data and obtain refined position data by DBSCAN Clustering position data obtained through AIS or RTU for AtoN. For this purpose, 21 position data of Gunsan Port No. 1 light buoy where RTU was installed among western waters with the most position errors were DBSCAN clustered using Python library. The minPts required for DBSCAN Clustering applied the value commonly used for two-dimensional data. Epsilon was calculated and its value was applied using the k-NN (nearest neighbor) algorithm. As a result of DBSCAN Clustering, position error data that did not satisfy minPts and epsilon were detected and refined position data were acquired. This study can be used as asic data for obtaining reliable position data of a light buoy installed with AIS or RTU for AtoN. It is expected to be of great help in preventing navigation safety accidents.

Influence of M.7 Apple Rootstock on Productivity and Fruit Quality of High Density 'Fuji', 'Hongro' and 'Sansa' Apple Trees (M.7 사과 대목이 고밀식 '후지' , '홍로' , '산사' 사과나무의 생산량 및 과실품질에 미치는 영향)

  • Young Soon Kwon;Jeong-Hee Kim;Dong-Hoon Sagong;Jong Taek Park
    • Korean Journal of Environmental Agriculture
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    • v.42 no.3
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    • pp.239-252
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    • 2023
  • Most apple trees in South Korea are grafted on M.9 and M.26 rootstocks; however, these rootstocks are susceptible to fire blight. Although M.7 rootstocks are moderately resistant to fire blight, they tend to exhibit excessive vigor, which is unsuitable for high-density planting, unless weak cultivars are used. This study investigated the vegetative growth, yield, and fruit quality of apple trees grafted onto M.7, M.9, or M.26 rootstocks to assess the feasibility of establishing high-density apple orchards domestically using the M.7 rootstock a period of seven years (1-7 years after planting). Rootstocks were tested using three cultivars with contrasting induced vigor and harvesting times: vigorous and late-maturing 'Fuji,' moderate vigor and middle-maturing 'Hongro,' and low vigor and early-maturing 'Sansa.' The planting density was maintained constant, with 190 trees per 10 a. Primary thinning (leaving only the king fruit on clusters) was performed, whereas secondary thinning (controlling crop load) was not. Vegetative growth, accumulated yield per 10 a, and yield efficiency varied depending on cultivars and rootstocks; however, the cultivars had a more notable effect on fruit quality than the rootstocks. Biennial bearing often occurred in the M.26 rootstock. 'Fuji'/M.7 was overly vigorous for high-density planting. The fruit quality and accumulated yield per 10 a of M.7 were similar to those of M.9 with the 'Hongro' and 'Sansa' cultivars. In particular, 'Hongro'/M.7 did not show tree vigor reduction due to heavy crop load, and the degree of biennial bearing in 'Sansa'/M.7 was not particularly high. These results indicated that high-density apple planting using the M.7 rootstock was achievable using the 'Hongro' and 'Sansa' cultivars.

A Study on Personalized Emotion Recognition in Forest Healing Space - Focus on Subjective Qualitative Analysis and Bio-signal Measurement - (산림 치유 공간에서의 개인 감정 인지 효과에 관한 연구)

  • Lee, Yang-Woo;Seo, Yong-Mo;Lee, Jung-Nyun;Whang, Min-Cheol
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.2
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    • pp.57-65
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    • 2019
  • This study is a scientific approach to psychological factors such as emotional stability among various effects of forest resources. In order to carry out this study, the experiment was conducted on the subjects by setting the forest healing space as various spaces. The subjects who participated in this experiment were the students in their twenties and the average age was 22±1.25 years. The subjects were assessed for emotional words through subjective sequence evaluation in different designated forest healing spot. In addition, the emotional states that they actually perceived were measured by measuring the bio-signals to their perceived emotions. BMP, SDNN, VLF, LF, HF, Amplitude, and PPI were used for the bio-signal reaction experiment applied to this study. The results of this experiment were measured by Friedman test and Wilcoxon test for statistical analysis. n this study, 'good', 'clear', and 'uncomfortable' words were found statistically significant at the spot of forest healing space for subjective emotional vocabulary. In addition, SDNN, HF and Amplitude were statistically significant in the results of quantitative bio-signal measurement at each spot in the forest healing space. Based on the results of this study, we can suggest the application direction and strategic utilization plan of forest healing spot and forest resource utilization field. This is not only a guide for the users who use the facility through the spatial facilities and physical requirements for the emotion based forest-healing, but also can be used as a personalized emotional space design aspect.

Mediating Effect of Cognitive Function on the Relationship Between Vision, Hearing, and Activities of Daily Living (노인의 시각, 청각 및 일상생활활동의 관계에 대한 인지기능의 매개효과)

  • Nam, Sanghun;Hong, Ickpyo
    • Therapeutic Science for Rehabilitation
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    • v.12 no.1
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    • pp.65-78
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    • 2023
  • Objective : The typical decline in function due to aging includes limitations in vision, hearing, cognitive function, and activities of daily living. Therefore, this study evaluated the mediating effect of cognitive function on the relationship between vision and hearing and activities of daily living. Methods : The participants in this study were 36,767 persons from the long-term care database on older adults provided by the National Health Insurance Sharing Service. The extracted variables were: (i) independent variables: visual and hearing; (ii) dependent variables: basic and instrumental daily living activities; and (iii) mediator variables: cognitive function. Regression analysis was performed evaluate the mediating effects of the extracted variables. Results : Cognitive function showed a mediating effect of 30% on the relationship between vision and basic daily life activities and 42% in the relationship with instrumental daily life activities. The mediating effect was 50% in the relationship between hearing and basic activities of daily living, and 53% in the relationship with instrumental activities of daily living. Conclusion : Prevention programs for functional decline due to aging are in progress in Korea. Based on the results of this study, establishing a prevention program would help promote successful aging.

The Effects of Metacognition of Nursing Students on Proactivity of Problem Solving in Simulation Integrated with Problem-based Learning: Mediating Effects of Self-leadership (문제중심학습 통합 시뮬레이션교육에서 간호대학생의 메타인지가 문제해결 적극성에 미치는 영향: 셀프리더십의 매개효과를 중심으로)

  • Kyoung-Hwa Baek;Mi-Ock Cho;Jeong-Hwa Cho
    • Journal of Industrial Convergence
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    • v.20 no.12
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    • pp.203-211
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    • 2022
  • This study is a descriptive research study to investigate the mediating effect of self-leadership in the relationship between metacognition and proactivity of problem solving and the effect of metacognition on proactivity of problem solving of nursing students. 194 fourth-year nursing students who experienced in-school simulation practice at a university were selected as subjects for the study. Data were collected from September to December 2021 using a structured questionnaire. The collected data were analyzed by descriptive statistics, correlations and parametric regression using the SPSS 22.0 program. It was found that metacognition and problem-solving proactiveness and self-leadership had a quantitative correlation, and it was analyzed that metacognition and self-leadership had a significant effect on problem-solving proactiveness. Also, it was found that self-leadership is partially mediated in the relationship between metacognition and problem-solving proactiveness. According to the results of this study, it is necessary to develop a program that can improve the elements of metacognition and self-leadership in order to increase the problem-solving activity of nursing students through problem-centered learning integrated simulation education.

Factors Influencing the Satisfaction of In-School Clinical Practice Due to COVID-19 (COVID-19로 인한 교내 임상실습 영향요인)

  • Seung-Ju Kang;Chung-Sin Shim
    • Journal of Industrial Convergence
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    • v.20 no.12
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    • pp.245-250
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    • 2022
  • This study aims to identify the factors that affect the satisfaction of practice among nursing students who participated after replacing it with on-campus practice in a situation where practice was not possible due to COVID-19. Data were collected from 144 nursing students who participated in the clinical practice alternative campus practice conducted from September 13 to December 3, 2021 at a university located in G province. Data analysis was analyzed by ANOVA, Pearson's correlation coefficient, and hierarchical multiple regression analysis. The subject's satisfaction with practice is a general characteristic, self-efficacy (r=.540, p=.000), self-leadership (r=.553, p=.000), and critical thinking ability (r=.382, p=.000). , there was a significant correlation between major satisfaction (r= .248, p=.003). Variables that affect the clinical performance of the subjects were self-efficacy 20.4% (𝛽=.266, p=.047), self-leadership 51.2% (𝛽=.271, p=.047), and satisfaction with practice The explanatory power of the variables was 33.8%. Therefore, it is necessary to develop and apply a curriculum that can increase self-leadership and self-efficacy in order to increase the satisfaction of nursing students' practice.

A perceptual study on the correlation between the meaning of Korean polysemic ending and its boundary tone (동형다의 종결어미의 의미와 경계성조의 상관성에 대한 지각연구)

  • Youngsook Yune
    • Phonetics and Speech Sciences
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    • v.14 no.4
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    • pp.1-10
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    • 2022
  • The Korean polysemic ending '-(eu)lgeol' can has two different meanings, 'guess' and 'regret'. These are expressed by different boundary-tone types: a rising tone for guess, a falling one for regret. Therefore the sentence-final boundary-tone type is the most salient prosodic feature. However, besides tone type, the pitch difference between the final and penultimate syllables of '-(eu)lgeol' can also affect semantic discrimination. To investigate this aspect, we conducted a perception test using two sentences that were morphologically and syntactically identical. These two sentences were spoken using different boundary-tone types by a Korean native speaker. From these two sentences, the experimental stimuli were generated by artificially raising or lowering the pitch of the boundary syllable by 1Qt while fixing the pitch of the penultimate syllable and boundary-tone type. Thirty Korean native speakers participated in three levels of perceptual test, in which they were asked to mark whether the experimental sentences they listened to were perceived as guess or regret. The results revealed that regardless of boundary-tone types, the larger the pitch difference between the final and penultimate syllable in the positive direction, the more likely it is perceived as guess, and the smaller the pitch difference in the negative direction, the more likely it is perceived as regret.

The Effects of Pre-service Early Childhood Teachers' Teaching Ethics and Empathy on Awareness of Children's Rights (예비유아교사의 교직윤리와 공감능력이 아동권리인식에 미치는 영향)

  • Seung Hwa Jwa;Se Jin Eom
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.281-286
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    • 2023
  • We aimed to find out how teaching ethics and empathy affect the perception of children's rights with 297 pre-service early childhood teachers enrolled in the Department of Early Childhood Education at universities located in Busan. Through this, the purpose of this study was to present basic data for the development of a character development program for a high-quality early childhood teacher training institution. We derived the following research results. First, as a result of examining the degree of recognition of pre-service early childhood teachers' teaching ethics, empathy, and awareness of children's rights, the average value was high in the order of teaching ethics, awareness of children's rights, and empathy. Second, there was a positive correlation between pre-service early childhood teachers' empathy ability, teaching ethics and awareness of children's rights, and empathy ability and awareness of children's rights. Third, as a result of examining the relative effects of teaching ethics and empathy of pre-service early childhood teachers on the recognition of children's rights, social ethics was found to be the strongest predictor among teaching ethics. In this study, we identified that teaching ethics and empathy are effective in various approaches to promote awareness of children's rights in pre-service early childhood teachers. And the results of this study provides the basic data for the character development of desirable teachers that pre-service early childhood teachers should have.