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생물공정의 측정 및 새로운 공정변수의 개발

  • Heo, Won
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.51-52
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    • 2000
  • 생물공정의 운전에 있어서 적절한 공정변수가 부족한 경우가 많다. 이것은 멸균과정을 견딜 수 있는 신뢰성 높은 센서가 부족하기 때문이다[1]. 생물공정에 주로 사용되는 센서로서는 온도, pH, D.O., rpm, viscosoty 등이 있으나 이 센서들은 배양액의 물리적 혹은 화학적 상태를 측정할 수 있는 경우가 대부분이다[2]. 미생물의 대사활동과 관련이 있는 공정 변수로는 배출가스의 성분을 측정하여 얻을 수 있는 Oxygen uptake rate, Carbon dioxide evolution rate 및 Respiratory quotient가 있으며 현재 생물공정의 운전에 사용되고 있다[3]. 그러나 반복적인 센서의 보정과 연결관의 잦은 청소 및 보수를 필요로 하여 제한적으로 사용되고있는 실정이다. 자동화된 습식분석장치, Gas chromatograph, High Performace Liquid Chromatograph 혹은 Mass spectrophtometry 등을 온라인 샘플 처리장치와 연결하여 발효조의 배양액의 성분을 온라인으로 분석하고 공정의 운전에 응용하는 사례가 많이 발표되었다[4-6]. 고가의 장비 및 운전의 번거러움이나 추가적인 인력이 필요하므로 역시 특별한 경우에만 사용되고 있다. 이외에도 여러 종류의 온라인 센서 및 바이오 센서등이 개발되어 사용되고 있으나 역시 그 사용범위는 특수한 영역에 한정되어있다. 이와 같이 새로운 센서를 개발하여 공정변수를 측정하려는 시도중의 하나가 소프트웨어 센서의 개발이다. 이 것은 공정상에서 발생하는 1차 공정변수를 이용하여 배양액의 상태 혹은 2차적인 공정 변수를 추측해내는 것이다. 대부분의 경우 기존의 공정 변수를 사용하므로 추가적인 비용이 들지 않고 소프트웨어의 형태로 구현되므로 센서의 보정과 설치 및 유지관리의 노력이 매우 적은 장점이 있다. 본 연구에서는 생물공정에서 자동제어 과정에서 발생하는 여러 가지 공정상의 제어 신호로부터 새로운 공정 변수를 얻어내고자 시도하였다. 대부분의 생물공정에서는 pH의 자동제어가 필수적인데 자동제어 과정에서 발생하는 pH 제어 신호 및 pH의 변화 응답신호를 이용하여 배지의 완충용량의 변화와 알칼리의 소비속도를 온라인으로 측정할 수 있었다. 여기에 인공지능망을 설계하여 균체의 량을 온라인으로 추정하는 방법을 개발하였다 [7].산업용 발효조의 운전 온도는 주로 냉각수의 단속적인 공급에 의하여 항상 일정하게 조절된다. 따라서 냉각수의 냉각량을 측정하면 미생물의 배양시 발생하는 대사열량을 측정할 수 있게 된다. 본 연구에서는 실험실의 발효조를 냉각수의 단속적인 공급에 의하여 자동온도 조절이 되도록 개조하고 여기에 냉각수의 유출입 지점에 온도센서를 부착하여 냉각수의 온도를 측정하고 냉각수의 공급량과 대기의 온도 등을 측정하여 대사열의 발생을 추정할 수 있었다. 동시에 이를 이용하여 유가배양시 기질을 공급하는 공정변수로 사용하였다 [8]. 생물학적인 폐수처리장치인 활성 슬러지법에서 미생물의 활성을 측정하는 방법은 아직 그다지 개발되어있지 않다. 본 연구에서는 슬러지의 주 구성원이 미생물인 점에 착안하여 침전시 슬러지층과 상등액의 온도차를 측정하여 대사열량의 발생량을 측정하고 슬러지의 활성을 측정할 수 있는 방법을 개발하였다.

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Analysis on the Operation Status of National Education Information System (교육행정정보시스템의 운영실태분석)

  • Lee Dae-Sik;Jeong Ju-Young
    • Journal of Internet Computing and Services
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    • v.7 no.4
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    • pp.115-122
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    • 2006
  • The purpose of this paper is to suggest the improving plans about the system as searching an effective managing devices for NEIS with analysis of managing condition. For the plans, questionnaire was performed in the five sections to primary and secondary school teachers. Those were recognition about C/S, Introduction and conductive processing of NEIS, Satisfaction of specific task on school affairs and educational matters, its function, efficiency and security as well as technical problem. Those were recognition about C/S, Introduction and conductive processing of NEIS, Satisfaction of specific task on school affairs and educational matters, its function, efficiency and security as well as technical problem. The results are following: First. in spite of satisfaction with function of C/S, it have been some problems such as frequent patch and down of server. Secondly, although the introduction of NEIS was done in hurry without gathering teachers' opinions and sufficient research of system, it has been expected to settle down normally with correction and security. Thirdly, positive reaction was generally showed in research on satisfaction of specific task for school affairs and educational matters. Fourthly, most of teachers have known the functions of NEIS and recognized its convenience. Although they has not thought it reduced their work, they have realized it's convenient for dealing with statistics. Lastly, they think of NEIS as the essential system for the age of information, in spite of problems such as reveal of personal data and security. Therefore, we should keep eyes to problem of an invasion of human right. In addition, study deep into NEIS should be conducted with consistent security for the system. In order to it. technical and legal system should be carried out side by side.

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A Study of Prevention Model the Spread of Phishing Attack for Protection the Medical Information (의료정보 보호를 위한 피싱공격 확산방지모델 연구)

  • Choi, Kyong-Ho;Chung, Kyung-Yong;Shin, Dong-Kun
    • Journal of Digital Convergence
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    • v.11 no.3
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    • pp.273-277
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    • 2013
  • Phishing attacks have been implemented in smarter, more advanced ways with the passage of time. Hackers use intelligent phishing attacks to take over computers and to penetrate internal networks in major organizations. So, in this paper, a model for a prevention of phishing attack spread is conceptual designed in order to protect internal users and sensitive or important information from sophisticated phishing attacks. Internal users simultaneously utilize both external web and organizational mail services. And hackers can take the both side equally as a vector. Thus, packets in each service must be monitored and stored to recognize threatening elements from both sides. The model designed in this paper extends the mail server based security structure used in conventional studies for the protection of Internet mail services accessed by intranet users. This model can build a list of phishing sites as the system checks e-mails compared to that of the method that directly intercepts accesses to phishing sites using a proxy server, so it represents no standby time for request and response processes.

Perception of Privacy and Sensitivity of Personal Information among University Students (대학생들의 개인정보보호의 인식과 개인정보의 민감도에 대한 연구)

  • Boo, Yoo-Kyung;Noh, Jin-Won;Kim, Yun-Mi;Kim, Sung-Soo;Rha, Young-Ah
    • Culinary science and hospitality research
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    • v.21 no.5
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    • pp.25-37
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    • 2015
  • By studying the awareness level of students, for the need to protect personal information, and also by studying students' level of perception as to which information needs protection, this study aims to show that increased education is beneficial, and necessary, across all university majors. This increased education is necessary to improve information security, and increase the responsible sharing of private data which has many benefits, specifically in the Healthcare field. Utilizing student volunteers across multiple majors at a university in South Korea. These questionnaires measured the students' awareness of private information, their perception of private information and also the students' experience in receiving university level education regarding private information and the need for its protection. This study shows that, when compared to students in other fields, students in the field of public health had a higher level of awareness regarding the consequences of personal information disclosure for both public purposes and medical research. Within the parameters of this study, this outcome can be explained as the result of exposure to educational curriculum which contained information related to personal information protection. This increased education raised the student's awareness of which information is considered private, as well as, which information is valuable when responsibly shared. As a result, this study shows that an increase in education regarding information privacy, should be included in all university majors, and gives us evidence to support that this additional education is valuable to students at all levels and should be encouraged.

Recognition of Personal Health Record (개인보건정보기록에 대한 인지도)

  • Bae, Se-Eun;Kim, Ha-Yeon;Son, Hyeon-S.;Rhee, Hyun-Sill
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.4
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    • pp.1703-1710
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    • 2011
  • Objectives: Using a PHR(Personal Health Record) is very important for the management of chronic disease and health. The young age group in this study was asked to pretend that they were members in the old age group (adult group here after) in order to investigate the recognition level differences in such conditions. Methods: We conducted face to face surveys with two age groups. 131 Adults and 398 University students, from May 11 to 22 in 2009. The questionnaires were composed of 18 items. Results & Conclusion: Adults replied more favorably than University students in using PHR willingness(University group 3.3score, Adults 3.7score) and recommendation(university 3.1score, Adults 3.8score). Adults liked paper PHR (63.2%), whereas, University students favored electronic Personal Health Record (71.1%). University students were highly concerned about disclosing the information(4.5score) of their PHR. They thought the appropriate time of education for PHR is high school or University degree. Therefore, in the future, it is vital that a PHR for young age group should be begun in early education and that an ePHR should be developed.

Study on Air Quality in the Case of Chemical Fires Using Proton Transfer Reaction-Time of Flight Mass Spectrometer (양자전이 비행시간 질량분석기를 이용한 화학물질 화재 발생 시 대기질 조사 연구)

  • Kim, So-Young;Cho, Dong-Ho;Park, Jungmin
    • Fire Science and Engineering
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    • v.32 no.6
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    • pp.84-90
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    • 2018
  • Chemical accidents occur in various forms, such as explosions, leaks, spills, and fires. In particular, chemical accidents caused by fires seriously affect the surrounding air environment due to soot, causing anxiety to the residents. Therefore, it is important to identify the causative substances quickly and examine the influence of air quality in the surrounding area. In this paper, proton transfer reaction-time of flight mass spectrometry(PTR-ToFMS) was used to identify the causative material in a fire and monitor the air quality in real time. This analyzer is capable of real-time analysis with a rapid response time without sample collection and pretreatment. In addition, it is suitable for quantitative and qualitative analysis of most volatile organic compounds with high hydrogen affinity, to identify the cause of fire and examine the influence of ambient air. In April 2018, when a local fire occurred, methanol, acetone, and methyl ethyl ketone were the main causative agents in PTR-ToFMS.

3-Dimensional Numerical Analysis of Air Flow inside OWC Type WEC Equipped with Channel of Seawater Exchange and Wave Characteristics around Its Structure (in Case of Irregular Waves) (해수소통구를 구비한 진동수주형 파력발전구조물 내 공기흐름과 구조물 주변에서 파랑특성에 관한 3차원수치해석(불규칙파의 경우))

  • Lee, Kwang Ho;Lee, Jun Hyeong;Jeong, Ik Han;Kim, Do Sam
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.30 no.6
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    • pp.253-262
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    • 2018
  • Oscillating Water Column (OWC) Wave Energy Converters (WEC) harness electricity through a Power-Take-Off (PTO) system from the induced-airflow by seawater oscillating inside a chamber. In general, an air chamber with a relatively small cross-sectional area is required compared to seawater chamber to obtain high-velocity air in the PTO system, and in order to simulate an accurate air flow rate in the air chamber, a three-dimensional study is required. In this study, the dynamic response of OWC-WEC that is equipped with the channel of seawater exchange for the case of irregular waves has been numerically studied. The open source CFD software, OLAFLOW for the simulation of wave dynamics to the openFOAM and FOAM-extend communities, was used to simulate the interaction between the device and irregular waves. Based on the numerical simulation results, we discussed the fluctuation characteristics of three dimensional air flow in the air-chamber, wave deformation around the structure and the seawater flow inside the channel of seawater exchange. The numerical results the maximum air flow velocity in the air-chamber increases as the Ursell value of the significant wave increases, and the velocity of airflow flowing out from the inside of air chamber to the outside is greater than the speed of flowing into the air chamber from the outside.

Analysis of the Characteristics of the Seismic source and the Wave Propagation Parameters in the region of the Southeastern Korean Peninsula (한반도 남동부 지진의 지각매질 특성 및 지진원 특성 변수 연구)

  • Kim, Jun-Kyoung;Kang, Ik-Bum
    • Journal of the Korean Society of Hazard Mitigation
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    • v.2 no.1 s.4
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    • pp.135-141
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    • 2002
  • Both non-linear damping values of the deep and shallow crustal materials and seismic source parameters are found from the observed near-field seismic ground motions at the South-eastern Korean Peninsula. The non-linear numerical algorithm applied in this study is Levenberg-Marquadet method. All the 25 sets of horizontal ground motions (east-west and north-south components at each seismic station) from 3 events (micro to macro scale) were used for the analysis of damping values and source parameters. The non-linear damping values of the deep and shallow crustal materials were found to be more similar to those of the region of the Western United States. The seismic source parameters found from this study also showed that the resultant stress drop values are relatively low compared to those of the Western United Sates. Consequently, comparisons of the various seismic parameters from this study and those of the United States Seismo-tectonic data suggest that the seismo-tectonic characteristics of the South eastern Korean Peninsula is more similar to those of the Western U.S.

Characteristics of Water Budget on Throughfall and Stemflow in Pinus densiflora and Quercus acutissima (소나무와 상수리나무림의 임내우 물수지 특성)

  • 이헌호;박재철
    • Korean Journal of Environment and Ecology
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    • v.12 no.3
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    • pp.259-270
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    • 1998
  • This study, as an essential research to develope a mountainous runoff model, was conducted to clarify the hydrologic character and water budget equation of Pinus densiflora and Quercus acutissima. Net rainfall quantity division for two species was investigated at Youngsung experiment forest and Yeungnam University for 30 months(Sep. 1995-Jun. 1998). The results were summarized as follows; 1. The percentages of throughfall and stemflow to gross precipitation are 73.8% and 0.8% in the Pinus densiflora, and 76.9% and 3.8% in the Quercus acutissima, respectively 2. In the Pinus densiflora, regression fomula of stemflow, throughfall, and net rainfall to gross precipitation are S$_{f}$ = 0.01GP-2.05 ($r^2$=0.54) T$_{f}$ = 0.79Gp - 26.04 ($r^2$=0.92), N$_{r}$ = 0.81Gp - 28.09 ($r^2$=0.92). Stemflow and throughfall increased in direct proportion to gross precipitation. 3. In the Quercus acutissima, regression fomula of stemflow, throughfall, and net rainfall to gross precipitation are S$_{f}$ = 0.03Gp + 12.25 ($r^2$=0.74), T$_{f}$ = 0.78Gp + 19.75 ($r^2$=0.96), N$_{r}$ = 0.81Gp + 3199 ($r^2$=0.96), respectively. Comparing with two species, gross precipitation has a much larger effect on the stemflow and throughfall of Quercus acutissima than those of Pinus densiflora. 4. In the analysis of intercorrelation between stemflow and throughfall of each species and crown area(CA), diameter at breast height(DBH), and gross precipitation(Gp), correlation coefficient was higher by following order at each species; Gp>CA>DBH on stemflow of Pinus densinora, Gp>DBH>CA on stemflow of Quercus acutissima, and Gp>CA>DBH on throughfall of Pinus densiflora and Quercus acutissima.ssima.

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Social Anxiety in Korean Society (한국 사회의 사회적 불안에 관한 연구)

  • Young-Oh Hong;Kwan-Jae Song;Su Ae Park;Hyejin Lee;Jae Chang Lee
    • Korean Journal of Culture and Social Issue
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    • v.12 no.1
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    • pp.129-160
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    • 2006
  • The purposes of this study were to find 1) the realities of social anxiety and perception of various kinds of social problems that exists in Korean society as well as the perception on the events that causes the social anxiety, 2) to see the difference of perceived level of social anxiety through variables of social demography and difference of perception on Korean society. The sample was distributed according to population size distinguishing the nation to 6 regions. The data of 1,375 adult respondents were analysed. The results are as follows. First of all, respondents mentioned that the most immediate problem to be solved in Korean society was financial anxiety, and the most desirable state of society was when the society is financially stabled. Single question was measured about social anxiety of Korean society and scored 6.84 from full marks of 10, showing difference in variables for instance sex, age, and subjective S.E.S. where women, aged under 20, and perceived low class group showed the highest rate of social anxiety. However, there weren't any difference found in social anxiety of the variables like presence of religion, educational background, residence, and monthly average household income. Also, there were differences in level of social anxiety according to the difference of perception of Korean society. Higher the perceived unpredictability, uncontrollability, and unmovability to the upper class, unfairness, and uncertainty, unreliability of the Korean society, higher the social anxiety. And the lower the perceived chance of success of reformation, higher the social anxiety. It was also found that the perceived social anxiety is influenced by social accidents and phenomenon as unemployment, economic depression, and the gap between rich and poor as well as the increase of crime through effluence of personal information. Finally the limitations and implications of this study were discussed.