• Progress in Medical Physics
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• v.14 no.4
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• pp.259-267
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• 2003

In vivo $^1$H magnetic resonance spectroscopy (MRS) at 4.7 T was applied to investigate the cerebral metabolite changes of mice brain before and after experimental brain trauma. In vivo $^1$H MR spectra were acquired from a voxel covering right parietal cortex in normal brain, used as control subjects. After experimental brain trauma using the fluid percussion injury (FPI) method, $^1$H MR spectra were acquired from the same lesion three days after trauma. Metabolite ratios of the injured lesion were compared to those of controls. After trauma, N-acetylaspartate (NAA)/creatine (Cr) ratio, as a neuronal marker was decreased significantly versus controls, indicating neuronal loss. The ratio of NAA/Cr in traumatic brain contusion was 0.90$\pm$0.11, while that in normal control subjects was 1.13$\pm$0.12 (P=0.001). Choline (Cho)/Cr ratio had a tendency to rise in experimental brain contusion (P=0.02). Cho/Cr ratio after trauma was 0.91$\pm$0.17 while that before traumas was 0.76$\pm$0.15. Cho/Cr ratio was increased and this might indicate a inflammatory activity. However, no significant difference of [(glutamate＋glutamine) (Glx)]/Cr was established between experimental traumatic brain injury models and normal controls. Lactate (Lac)/Cr ratio was appeared as a sign of shifted posttraumatic energy metabolism and increased versus controls. These findings strongly suggest that in vivo $^1$H MRS may be a useful modality for clinical evaluation of traumatic contusion and could aid in better understanding the neuropathologic process of traumatic contusion induced by FPI. In the present study, in vivo $^1$H MRS was proved to be a useful non-invasive method for in vivo diagnosis and monitoring of posttraumatic metabolism in models of brain contusion.

• The korean journal of orthodontics
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• v.40 no.2
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• pp.66-76
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• 2010

Objective: Obstructive sleep apnea (OSA) is a common disorder which is characterized by a recurrence of entire or partial collapse of the pharyngeal airway during sleep. A given tidal volume must traverse the soft tissue tube structure of the upper airway, so the tendency for airway obstruction is influenced by the geometries of the duct and characteristics of the airflow in respect to fluid dynamics. Methods: Individualized 3D FEA models were reconstructed from pretreatment computerized tomogram images of three patients with obstructive sleep apnea. 3D computational fluid dynamics analysis was used to observe the effect of airway geometry on the flow velocity, negative pressure and pressure drop in the upper airway at an inspiration flow rate of 170, 200, and 230 ml/s per nostril. Results: In all 3 models, large airflow velocity and negative pressure were observed around the section of minimum area (SMA), the region which narrows around the velopharynx and oropharynx. The bigger the Out-A (outlet area)/ SMA-A (SMA area) ratio, the greater was the change in airflow velocity and negative pressure. Conclusions: Pressure drop meaning the difference between highest pressure at nostril and lowest pressure at SMA, is a good indicator for upper airway resistance which increased more as the airflow volume was increased.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.11
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• pp.1027-1033
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• 2010

A two-phase (gas-liquid) flow is a common phenomenon in fluidic systems, e.g., fluidic systems in the electro-magnetic or nuclear power generation industry and in the steel industry. The measurement of a two-phase flow is important for guaranteeing the safety of the system and for achieving the desired performance. The measurement of the void fraction, which is one of the parameters of the two-phase flow that determines the pressure drop and heat transfer coefficient, is very important. The time resolution achieved by employing the impedance method that can be used to calculate the void fraction from the impedance of the fluid is high because the electric characteristics are taken into account. Therefore, this method can be employed to accurately measure the void fraction without distortion of flow in real time by placing electrodes on the walls of the tubes. Coney analytically studied a ring-type impedance meter, which can be employed in a circular tube. The aim of this study is to experimentally verify the robustness of a three-ring impedance meter to variations in the electric conductivity of the fluid; this robustness was suggested by Coney but was not experimentally verified.

• Plant Journal
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• v.10 no.2
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• pp.38-47
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• 2014

Renewable Portfolio Standards was introduced into the system in Korea in 2012. Interest in the unutilized and renewable energy sources is increasing. and these being actively investigated. An organic rankine cycle has emerged as an alternative in order to take advantage of bio-gas engine heat of sewage treatment plants whose capacity is 1500 kW. The organic rankine cycle power system was simulated by a simulator which is a commercial program of power plant design and performance analysis. The biogas engine is operated by $460^{\circ}C$ and 2.7 kg/s flow rate in the sewage treatment plant. Working fluids(R-601a, R-123, R-245fa) are selected to use in ORC power system in this temperature range. It was the isopentane that is the best performance among three working fluids. It could be obtained net power of 163.1 kW and efficiency of 13.66% from isopentane in the simulation.

• Journal of Biomedical Engineering Research
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• v.24 no.4
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• pp.293-299
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• 2003

In this paper, the correlation of Pressure drop about the Newtonian and non-Newtonian fluid was investigated experimentally for vibrating intravascular lung assist device (VIVLAD) and we determined correlation equation to make a prediction about Pressure drop for designing VIVLAD. Design conditions to predict the pressure drop of the modules were studied through an experimental modeling before inserting the artificial lung assist device into as venous. Experiments were performed by distilled water, glycerol/water mixed solution(40% glycerol) of Newtonian fluids. and the bovine blood of non-Newtonian fluids. These fluids were flowed outside and parallel of hollow fiber membranes. Also we measured pressure drop according to the number of the fiber membranes which ware inserted into the inside diameter of shell of 3 cm, and developed the prediction equations by curve fitting method based on correlation between the experimental pressure drop and the frontal area or the packing density of device. The result showed that the Pressure drop and the friction factor of the water/glycerol mixed solution were similar to that of bovine blood. It was showed that the water/glycerol mixed solution (40% glycerol) could be used for measuring the pressure drop and the friction factor instead of the bovine blood. Also, we could estimate the prediction equation of pressure drop and friction factor as the function of Packing density at the number of hollow fibers. We obtained the reliance of the prediction equations because the pressure drop and the friction factor measured from the experiments were similar to that from the prediction equation. These results may be used to further usefulness for the design of VIVLAD.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.6
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• pp.613-619
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• 2017

Recently, the size of container ships has been progressively increasing, and much attention is required for safe navigation in shallow areas such as coastal waters and ports due to increases in draft. It is necessary to understand the characteristics of ship motion not only in still waters but also with waves. Especially in shallow regions, squat due to the vertical movement of the ship can be an important evaluation factor for the safe navigation, and wave drift force acting in the horizontal direction can have a great influence on the maneuverability of a ship. In this study, a numerical simulation using computational fluid dynamics has been performed for the wave exciting force acting in the vertical direction and the wave drift force acting in the horizontal direction for a very large container vessel sailing in shallow zone. As a result, it was found that total resistance in still waters greatly increased in shallow water. Wave drift force was shown to decrease given longer wavelengths regardless of water depth. It was observed that the wave exciting force in shallow water was considerably larger than at other water depths. As wave height against the central part of the ship lowered, the aft side rose.

• Korean Journal of Remote Sensing
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• v.31 no.2
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• pp.65-75
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• 2015

In this study, the observation environment of surface wind at an automatic weather station (AWS 288) located at Naei-dong, Mirang-si was analyzed using a computational fluid dynamics (CFD) model and geographic information system (GIS). The 16 cases with different inflow directions were considered before and after construction of an apartment complex around the AWS 288. For three inflow directions (south-south-westerly, south-south-easterly, and north-north-westerly), flow characteristics around the AWS 288 were investigated in detail, focusing on the changes in wind speed and direction at the AWS location. There was marked difference in wind speed between before and after construction of the apartment complex in the south-south-westerly case. In the south-south-easterly and north-north-westerly cases which were frequently observed at the AWS 288, the construction of the apartment complex had no marked influence on the observation of surface wind.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.1
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• pp.75-81
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• 2003

Rheological properties of micronized full-fat soyflour (MFS ) milk were determined according to solid content, heat-treatment and type of coagulants. Heat-treated MFS milk showed a pseudoplastic flow pattern. The consistency and flow index of heated MFS milk was greatly affected by increasing the concentration of MFS and/or soy protein isolate (SPI). Apparent viscosity of MFS milk was gradually decreased by heating below 6$0^{\circ}C$, but was drastically increased by raising temperature further. Addition of coagulants and SPI resulted in dropping the temperature that allows to increase apparent viscosity drastically. A coagulant for MFS tofu was formulated based on the gelling Property of a single coagulant. The textural properties of MFS tofu were improved using 7.1% total protein fortified with SPI.

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05b
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• pp.857-863
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• 1998

배관내에서 서로 다른 온도의 유체가 밀도차에 의해서 층이 분리된 채 존재하는 현상을 열성층 (thermal stratification) 현상이라 부르며, 이 현상에 의한 과도한 열응력은 배관의 건전성을 저해할 수 있다. 국내 원전의 경우 영광 3,4호기 이전의 밀림배관에서는 열성층 영향을 고려치 못하여 이에 대한 건전성 평가가 요구되고 있다. 본 연구에서는 고리 4호기 가압기 밀림배관을 대상으로 밀림배관내 유동해석 및 발전소 전 운전조건에 대하여 밀림배관 단면 온도분포 실측실험을 통하여 열성층화 현상의 발생 정도를 확인 하였으며 실측 온도 데이터를 이용하여 열응력해석 등을 수행함으로써 밀림배관의 열성층 영향을 평가한 결과 건전함이 확인되었다.

• Journal of Advanced Marine Engineering and Technology
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• v.25 no.6
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• pp.1195-1202
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• 2001

The flow characteristics in a bifurcated duct are investigated experimentally. Physical properties such as mean velocity vectors, mean x-y stress distributions, mean vorticity and total pressure distributions are Obtained for three different Reynolds numbers(578, 620, 688) Using PIV measurements and CFD analysis. Also, three different rates of discharge Q=26.11 l/min, Q=28.11 $\ell$/min, Q=31.17 $\ell$/min) were selected foy experimental conditions. The results of this study would be useful to the engineer in designing the flow systems for heating, ventilation, air conditioning and wastewater purification plants.