• Title/Summary/Keyword: 유전자 행렬 맵핑

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Detection of major genotypes combination by genotype matrix mapping (유전자 행렬 맵핑을 활용한 우수 유전자형 조합 선별)

  • Lee, Jea-Young;Lee, Jong-Hyeong;Lee, Yong-Won
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.3
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    • pp.387-395
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    • 2010
  • It is important to identify the interaction of genes about human disease and characteristic value. Many studies as like logistic analysis, have associated being pursued, but, previous methods did not consider the sub-group of the genotypes. So, QTL interactions and the GMM (genotype matrix mapping) have been developed. In this study, we detect the superior genotype combination to have an impact on economic traits of Korean cattle based on the study over GMM method. Thus, we identified interaction effects of single nucleotide polymorphisms (SNPs) responsible for average daily gain(ADG), marbling score (MS), carcass cold weight (CWT), longissimus muscle dorsiarea (LMA) using GMM method. In addition, we examine significance of the major genotype combination selected by implementing permutation test of the F-measure which was not obtained by Sachiko et al.