• The Korean Journal of Pain
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• v.5 no.2
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• pp.213-220
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• 1992

The sciatic nerves of anesthetized rabbits were exposed and stimulated by a nerve stimulator in order to observe the myoneural response. These rabbits were divided into three groups and respectively injected with morphine (Group 1), meperidine(Group 2) and pentazocine (Group 3). The sciatic nerves were stimulated periodically and gait changes were observed to see the myoneural activity after the injections. When the distal part of the sciatic nerves were stimulated by the nerve stimulator after the respective drug injections, the normal muscle twitch responses were observed in all the progressional stages of Group 1. However, in Group 2 and 3, the muscle twitch responses decreased gradually, finally disappearing after approximately 10 minutes in these two groups. Complete motor paralysis continued for about 60 minutes. The muscle reactions returned to normal approximately 90 minutes after injection. Specimens drug-injected tissues were severed 4 hours, 24 hours and 1 week after injection respectively. These tissue were investigated under light as well as electron microscopy. The tissue revealed rare to moderate vacuolizations scattered in the axons of the myelinated and unmyelinated nerves of some of the specimens; however, there were no significant pathologic lesions. These results provide evidence that neurophysiologically, meperidine and pentazocine have a local anesthetic-like effect such as motor paralysis, but morphine does not. In addition, the results indicated that neurohistologically, the three narcotics have no significant toxic effects on the nerve tissue.

• Journal of Advanced Navigation Technology
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• v.14 no.6
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• pp.1002-1009
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• 2010

I made the axon to the electrical transmission model and then constructed electrical equivalent model using Kirhhoff's current law and voltage law in this paper. I calculated various axon parameters in order to analyze the electrical potential hehavior versus minute distance chang of axon. The transmission velocity of unmyelinated nerve is proportional to square root of axon diameter, while that of myelinated nerve is directly proportional to its diameter. Because the transmission of myelin sheath is independent of voltage unlike unmyelinated sheath, the Hodgkin-Huxley model across the membrane is not so precise.

• Korea Petroleum Association Journal
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• no.5 s.147
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• pp.6-8
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• 1993

• Journal of Ginseng Research
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• v.27 no.3
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• pp.103-109
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• 2003

We investigated the effect of ginseng total saponin (GTS) on the regeneration process of experimentally crush injured rat sciatic nerves. The bilateral sciatic nerves of fifty adult male Sprague-Dawley rats were compressed surgically with a straight hemostat for 30 seconds with 1 mm width. Twenty rats were divided into four groups to test the dose-dependent effect of GTS (0, 50, 100, or 150 mg/kg, i.p.). Saline for vehicle control group or GTS dissolved in saline was administerd for three weeks. After that period of time, the numbers of total myelinated axon and degenerated myelin in the sciatic nerves of bilateral legs were examined and analyzed using image analysis system to confirm a morphological effect of GTS. We found that the most effective concentration of GTS for the regeneration of damaged sciatic nerve was 150 mg/kg. In another set of experiment, thirty rats were divided into two groups as saline-treated vehicle group and GTS-treated group (150 mg/kg, i.p.) for three weeks. Every week we examined the numbers of total myelinated axon and degenerated myelin in the sciatic nerves of bilateral legs using image analysis system to evaluate the effect of GTS on injured nerves. We found that the regeneration of damaged sciatic nerves was facilitated in GTS-treated group compared to saline-treated group until two weeks. However, after that period of time we could not observe the significant difference between saline-treated group and GTS-treated group. These results suggest that GTS is a useful adjuvant therapy for the regeneration of the peripheral nerve injury in short period of treatment.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2006.06a
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• pp.195-202
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• 2006

본 연구에서는 보다 효과적인 기업부도예측을 위하여, 동계적 방법과 인공지능 방법을 결합한 통합모형을 제시하였다. 이를 위하여 통계적인 모형 중에서 가장 널리 활용되고 있는 다변량 판별분석, 로지스틱 회귀분석과 인공 지능적인 방법으로서 최근 널리 사용되고 있는 인공신경망, 규칙유도기법, 베이지안 망의 5가지 방법론을 통합한 Voting with Performance & Weights from ANN(WP-ANN) 통합모형을 제시하였다. 실험결과, 본 연구에서 제안한 WP-ANN 통합모형은 다변량 판별분석, 로지스탁 회귀분석, 인공신경망, 규칙유도기법, 베이지안 망 등의 단일모형과 비교한 결과 가장 예측정확성이 유수한 것으로 나타났다. 따라서 본 연구를 통해 기업부도예측에 있어서 WP-ANN 통합모형이 기존의 모형들에 비해 우수한 예측정확성을 나타냄을 알 수 있었다.

• Korean Journal of Veterinary Research
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• v.6 no.1
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• pp.82-91
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• 1966

Studies On the myelinated fibers of the recurrent laryneal nerves were made in five, species of domestic animals namely dog, pig, goat, horse and Korean ox. Throughout the studies, the following characteristics of the myelinated fibers were obtained. 1. The number, size and cross sectional area of the myelinated fibers seemed to be proportionally related to the animal body weights. 2. The highest peak of diameter size frequency distribution of the myelinated fibers, observed at the right cranial level, in dog, goat and horse were 4-6 micron group, while in the case of Korean ox, 10-12 micron group was the highest. 3. The highest peak of diameter size frequency distribution of the myelinated fibers, observed at the right caudal level of Korean ox was 6-8 micron group, and 4-6 micron group was the highest in the other animals. 4. The highest peak of diameter size frequency distribution of the myelinated fibers obsered at the left cranial level was same to that of right cranial level. 5. The highest peak of diameter size frequency distribution of the myelinated fibers, observed at the left caudal levels in dog, goat, horse and Korean ox was 4-6 micron group, while in case of pig, $14-16{\mu}$ group was the highest. 6. The largest cross sectional areas were found in the group of 10-16 micron in all species of animals. 7. The fiber diameter size frequency distribution of recurrent laryngeal nerves of dog, goat, pig and horse were bimodal and Korean ox seemed to be a unimodal.

• Investigative Magnetic Resonance Imaging
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• v.18 no.2
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• pp.167-170
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• 2014

The medial longitudinal fasciculus (MLF) is myelinated composite tract, lying near the midline, ventral to periaqueductal grey matter that plays a key role in coordinating eye movements. A lesion of the MLF results in an ipsilateral adduction deficit and a contralateral abducting nystagmus, referred to as an internuclear ophthalmoparesis. The blended tract with adjacent white matter in pons and midbrain is indistinguishable on brain imaging such as CT and MRI. Until now, to the best of our knowledge, MLF is not delineated on in vivo MRI. We present a case showing the whole connecting courses of MLF lesion on MRI in a patient with inflammatory demyelinating disorder.

• Journal of Oriental Neuropsychiatry
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• v.28 no.3
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• pp.275-286
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• 2017

Objectives: To suggest the basis of clinical applications through qualitative and quantitative analysis of mentalizing the rooms of mind in the mindfulness meditation program. It is one of the M&L psychotherapy techniques that enables observing the mind more objectively by structuring, visualizing and embodying state of the mind at the moment of drawing a room of the mind. Methods: In this study, we conducted 5t mindfulness meditation program sessions with 85 college students studying Oriental Neuropsychiatry at the University of Oriental Medical College. Before and after the program, data checked the FFMQ and drew the room of mind. Qualitative analysis by subjects were analyzed using qualitative and quantitative methods. Results: First, results of the quantitative analysis revealed significant difference between pre-and post on describing one of the FFMQ sub-factors. However, there were no statistically significant other factors. Second, qualitative analysis results follow as: It extracted 2 keywords including 'viewpoint as a therapist' and 'viewpoint as a client' and 3 consisting words 'positive response', 'negative response', 'ambiguous response'. Conclusions: Mentalizing the room of mind is the work of visualizing, diagramming, objectifying, and specifying the mind of this moment. It is concerned that the value of clinical use is high as a useful tool to increase concentration of meditation and observe and evaluate changes of mind before and after treatments.

• The Journal of Pediatrics of Korean Medicine
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• v.26 no.4
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• pp.71-76
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• 2012

Objectives: The purpose of this study is to report the clinical effects of Korean medical treatment on the patient with cervical radiculopathy. Methods: A 16-year-old female patient, who was suffering from the cervical radiculopathy on her Lt. shoulder: ROM limit, swelling and arthralgia, was treated by herbal medicine, physical therapy, acupuncture and pharmacupuncture. Results: As a result, the patient's left upper limb disability was improved by Korean herbal medicine (ssanghwatang hap gamiseokyungtang), hominis placenta (Ja-ha-geou) pharmacupuncture and physical therapy. Conclusions This study showed that Korean medical treatments can be an effective choice for cervical radiculopathy.

• Journal of Korean Neurosurgical Society
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• v.29 no.7
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• pp.940-944
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• 2000

The giant-cell tumor is uncommon. It occurs in the long bones and vertebral localization is much less common, particularly in thoracic spine. We present a case of a 37-year-old man suffering from severe back pain. Affected vertebral bodies were removed by transthoracic approach and the spine was reconstructed with iliac bone autografts and internal fixation device(Kaneda) between T 8 and T 11. Histologoical diagnosis was giant-cell tumor, and pertinent literature was reviewed.