• Title/Summary/Keyword: 유동안정기

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The Effect of Drug Release from Osmotic Pellet Related to the Various Ratio of $Eudragit^{(R)}$ RL and RS ($Eudragit^{(R)}$ RL과 RS의 비에 따른 삼투정 펠렛의 약물방출에 미치는 영향)

  • Youn, Ju-Yong;Ku, Jeong;Lee, Soo-Young;Kim, Byung-Soo;Kim, Moon-Suk;Lee, Bong;Khang, Gil-Son;Lee, Hai-Bang
    • Polymer(Korea)
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    • v.31 no.4
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    • pp.329-334
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    • 2007
  • Osmotic pellet system, which is one of the oral drug delivery systems, has been developed to improve manufacturing process, reduce product cost and other problems of osmotic tablet systems. Osmotic pellet is consisted of water swellable seed layer, drug layer, and membrane layer. Among them, the membrane layer plays an important role in a control of the drug release. In this work, we examined the effect of ratio for Eudragit RL and RS on the drug release behavior. Osmotic pellet with nifedipine as a model drug was easily obtained in a good yield by fluidized bed coater. Osmotic pellet showed round morphology with a range of size $1300{\sim}1500\;{\mu}m$. In the experiment of nifedipine release, the release amount increased with the increase of the ratio of Eudragit. This is due to the fact that Eudragit RL contains more hydrophilic quaternary ammonium group than Eudragit RS. Additionally, the release amount was retarded with increasing the membrane thickness. There are no differences in the release amount measured at the different pH 1.2, 6.5, 6.8, and 7.2. In conclusion, it was found that the drug release from osmotic pellets depended on the composition ratio and coating thickness of membrane layer.

Breeding of A New Saxifraga fortune Cultivar (Hybrid) 'Crystal' with Light Pink on a White Green Ground Colored Petals for Pot Flower (연한 녹색 바탕에 밝은 핑크색 꽃의 분화용 바위떡풀 신품종 '크리스탈' 육성)

  • Suh, Jong-Taek;Hong, Su-Young;Yoo, Dong-Lim;Nam, Chun-Woo;Ryu, Seung-Yeol;Lee, Eung-Ho
    • Horticultural Science & Technology
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    • v.30 no.2
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    • pp.224-228
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    • 2012
  • A new $Saxifraga$ $fortunei$ cultivar 'Crystal' was bred by crossing 'Dotaerang' with light pink and light Green (RP 58D) colored petals and 'Rocksun' with light pink and light green white (RP62A + GW157A) colored petals. The selection and flower characterization were conducted from 2004 to 2007 in a greenhouse of the National Institute of Highland Agriculture. The flowering of 'Crystal' occurred from September 21 for 31 days. The number of flowers per plant was 279.0 with many flowering habit. The flower coloration was mixed light pink and green white (RP62D + GW157B) at the opening. The number of petals were 7.0, with a width of 2.1 cm and length of 1.8 cm. The plant height was 15.3 cm and number of leaves was 133.7. 'Crystal' cultivar can be used for pot flower. Fifty percent shading is a good cultural practice against direct sunlight and soft rot disease would occurs usually by over-irrigation. 'Crystal' cultivar was registered as a new variety with No. 3466 at Korea Seed and Variety Service in April of 2011 year.

Synthesis and characterization of polymer electrolyte membrane for fuel cell including sulfonated bis (4-fluorophenyl) phenylphosphine oxide (술폰화된 비스(4-플루오로페닐) 페닐포스핀옥사이드를 포함한 연료전지용 고분자 전해질막의 합성과 특성분석)

  • Yoo, Eun Sil;Nahm, Kee Suk;Yoo, Dong Jin
    • Journal of Energy Engineering
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    • v.25 no.4
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    • pp.176-183
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    • 2016
  • This study relates to a polymer electrolyte membrane for improved performance fuel cell, were researched with respect to properties required for driving a fuel cell. The bis(4-fluorophenyl)phenyl phosphine oxide was sulfonated using fuming sulfuric acid. Synthetic hydrophilic oligomer and the hydrophobic oligomer and the block copolymers were prepared via aromatic nucleophilic substitution polycondensation. A block copolymer structure and degree of sulfonation was analyzed by $^1H$-NMR and gel permeation chromatography(GPC) analysis. Thermal stability was confirmed by thermogravimetric analysis(TGA), block copolymer was stable at high temperature(>$200^{\circ}C$), The ion conductivity was measured in order to demonstrate the performance of fuel cell. Synthesis membrane was the increase of temperature was improved conductivity up to 58 mS/cm due to the influence of the developed ion clusters. The phase separation of the polymer was observed to make AFM analysis.

Numerical Study of Turbulent Heat Transfer in Helically Coiled Tubes (나선형 튜브내의 난류 열전달에 대한 수치적 연구)

  • Yoon, Dong-Hyeog;Park, Ju-Yeop;Seul, Kwang-Won
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.8
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    • pp.783-789
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    • 2012
  • In this study, turbulent flow and heat transfer characteristics in a helically coiled tube have been numerically investigated. Helically coiled tubes are commonly used in heat exchange systems to enhance the heat transfer rate. Accordingly, they have been widely studied experimentally; however, most studies have focused on the pressure drop and heat transfer correlations. The centrifugal force caused by a helical tube increases the wall shear stress and heat transfer rate on the outer side of the helical tube while decreasing those on the inner side of the tube. Therefore, this study quantitatively shows the variation of the local Nusselt number and friction factor along the circumference at the wall of a helical tube by varying the coil diameter and Reynolds number. It is seen that the local heat transfer rate and wall shear stress greatly decrease near the inner side of the tube, which can affect the safety of the tube materials. Moreover, this study verifies the previous experimental correlations for the friction factor and Nusselt number, and it shows that the correlation between the two in a straight tube can be applied to a helical tube. It is expected that the results of this study can be used as important data for the safety evaluation of heat exchangers and steam generators.

Characteristics of RDF Char Combustion in a Bubbling Fluidized Bed (기포 유동층 내에서 RDF 촤의 연소 특성)

  • Kang, Seong-Wan;Kwak, Yeon-Ho;Cheon, Kyoung-Ho;Park, Sung Hoon;Jeon, Jong-Ki;Park, Young-Kwon
    • Applied Chemistry for Engineering
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    • v.22 no.4
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    • pp.429-432
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    • 2011
  • The feasibility of applications of the char obtained from a gasification process of municipal-waste refuse derived fuel (RDF) as an auxiliary fuel was evaluated by combustion experiments. The higher heating value of the RDF char was 3000~4000 kcal/kg and its chlorine content was below the standard requirement demonstrating its potential as an auxiliary fuel. In the combustion exhaust gas, the maximum $NO_x$ and $SO_2$ concentrations were 240 ppm and 223 ppm, respectively. If an aftertreatment is applied, it is possible to control their concentrations low enough to meet the air pollutant emission standard. The HCl concentration was relatively high indicating that a care should be taken for HCl emission from the combustion of RDF. Based on the temperature distribution within the reactor, the concentration change of $O_2$ and $CO_2$, and the amount and the loss on ignition of solid residue, it was inferred that the combustion reaction was the most reliable when the excess air ratio of 1.3 was used.

Actual State of Structures and Environmental Control Facilities for Tomato Greenhouses in Chungnam Region (충남지역 토마토 재배온실의 구조와 환경조절설비 실태분석)

  • Nam, Sang-Woon;Kim, Young-Shik
    • Korean Journal of Agricultural Science
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    • v.36 no.1
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    • pp.73-85
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    • 2009
  • An investigation was conducted to get the basic data for establishing structural safety and environmental management of tomato greenhouses in Chungnam region. The contents of the investigation consisted of actual state of greenhouse structures and environmental control facilities. Most of greenhouses were arch type single-span plastic houses and they had too low height for growing tomatoes. Frameworks of multi-span greenhouses were suitable, but those of single-span were mostly insufficient. Every greenhouse had thermal curtain movable or covering fixed inside the greenhouse for energy saving, and heating facilities were mostly warm air heater. Irrigation facilities were mostly drip tube and controlled by manual operation or timer. Almost all of the greenhouses didn't install high level of environmental control facilities such as ventilator, air circulation fan, $CO_2$ fertilizer, insect screen, supplemental light, and cooling device.

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Study on Ventilation Efficiency of a Mechanically Ventilated Broiler House­(I)Summer Season (강제환기식 육계사내의 환기효율성 조사연구­(I)하절기)

  • 이인복;정문성;유병기;전종기;김경원;이승기
    • Journal of Animal Environmental Science
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    • v.9 no.2
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    • pp.103-112
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    • 2003
  • In this study, the distributions of internal climates such as air temperature, humidity, dust, ammonia gas, and air velocity were systematically measured at a mechanically ventilated broiler houses during summer season, with local weather data. The analysis was focused on the suitability, stability, and uniformity of internal climate, resulting in serious stress on chickens and decrease of productivity In the mechanically ventilated broiler house, the difference between measured and recommended air temperatures(suitability) was 10.4C in maximum during the summer time. The difference of air temperature in the house between day and night was $8.7^{\circ}C$ in maximum. And maximal hourly range of internal air temperature at 0.4m height from the floor was $3.7^{\circ}C$ suggesting it maintained thermal uniformity in the broiler house. The $NH_3$ and dust concentrations were pretty low because ventilation was fully performed. The air speed at chicken location was measured 2.2m/s and 1.7m/s, respectively without and with chicken existence.

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A Study on the Change of Masks for Goseong Ogwangdae Play - Before and after the designation of intangible cultural assets- (고성오광대 연희용 탈의 변화 양상)

  • Nam, Jin-A
    • (The) Research of the performance art and culture
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    • no.41
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    • pp.257-284
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    • 2020
  • Goseong Ogwangdae started academic research in the late 1950s and was designated as a national intangible cultural asset in 1964. From the time of the academic survey to the time of designation, it was recorded as using paper masks, but when the recording image was filmed in 1965, it was already changed to wooden masks. In 1960, before being designated as an intangible cultural asset, the number of masks, which was 9 points, gradually increased to 19 points in 1964. It is necessarily included in the leper, Chorani, Malttuki, Cheongbo-Yangyang, Halmi, and Jemilju, but the character of the yangban is not yet clearly differentiated. Hwangbongsa and Sangju appeared as bare faces, and consumption, milling, Cheongbo-Yangyang are used together with Bibi and inspiration. It can be guessed that Bibi was not the appearance of a foreign object with horns as it is now, considering that Bibi and Madangsoi were used together. Since 1965, shortly after the designation, the whole of the Goseong Ogwangdae mask has been changed to a wooden mask. All the characters except for resident, courtyard, and top-of-the-line are wearing masks. Bibi, Hongbaek, and service masks have never appeared until 1964. The Yangban was changed to the closing ceremony with six people in the order of Won-Yangban, Baekje, Heukje, Cheongje, Hongbaek, and Jonggadoryong. Starting in 1969, the mask enters the stable period where the kind is the same as the present. Bibi-Yangban uses both the Won-Yangban and the Jemilju uses the Somu, but all other characters use the individual mask to use a total of 18 masks. The Yangbans are clearly differentiated, and a total of seven Yangban appear. The reason why the change in the type of mask and the expression of material is so large is that the first generation of mask makers died and the tradition of mask production was cut off, but there is also a cause of the extreme change in the environment of the drama that the performers who joined after the designation had to face. Also, it is closely related to the change of the times when the meaning and weight of masking in masking has changed. At that time, the performers were not so tied to the current concept of 'original form' that they preserved the appearance of the designated time. Originally, Goseong Ogwangdae was centered on improvisation dance, not the formalized dance as it is now, and there was a certain fluid aspect in the retelling, so it was flexible in the use of masks even before the designation of cultural assets. Strict rules did not apply in the details, as it was a self-sufficient play by the performers, not an offer event. The form and contents of this fluid play are changed to preparation for the performance while preparing for the folk art contest. As the subject of the contest in self-sufficient play, dance, costumes, and props became more and more colorful as well as dancing, costumes, and props. As a result, participation in the contest brought about changes in the overall performance and changed the mask, which was accepted within the preservation society.