• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2017.06a
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• pp.40-43
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• 2017

본 논문은 딥러닝을 이용하여 대장통과시간(Colon Transit Time, CTT) 검사를 위한 단순복부 X-Ray 영상에서 방사선 비투과성 표지자(Radio-opaque Marker)를 자동으로 검출하는 기법을 제시한다. 대장통과시간 검사는 대장의 운동질환을 평가하는데 있어 가장 기본적인 방법으로 특히 만성 변비증 환자의 병태생리에 따른 유형 분류와 치료 계획을 설정하는데 큰 도움을 주고 있으며, 내과적 또는 외과적 치료 후 평가에도 유용한 검사이다. 대장통과시간 검사는 방사선 비투과성 표지자가 내재되어 있는 캡슐을 복용한 뒤 주기적으로 단순복부 X-Ray 촬영을 통해 구간별로 남아있는 표지자의 수를 세고, 이를 통해 구역별 통과시간을 측정한다. 이 과정에서 판독의가 직접 표지자의 위치 및 개수를 세기 때문에 많은 시간이 필요하게 된다. 따라선 본 논문에서는 이러한 단점을 보완하기 위해 딥러닝 기법을 사용하여 X-Ray 영상 내에서 표지자의 위치를 자동 파악하는 기법을 제시한다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.06a
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• pp.66-67
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• 2022

등부표는 항로표지 중 유일하게 해상에 설치되는 항로표지이다. 등부표의 중심은 침추이지만, 항해자에게 시각적으로 확인되는 등부표의 실제위치는 외력에 의해 지속적으로 표류한다. 이러한 등부표의 위치를 확인하기 위하여 지난 5년간(2017-2021년) 전국 255기의 등부표 위치를 분석하였다. 분석결과 Data 오류는 17.94%였으며, 위치는 집중형, 이격형 등으로 구분되었다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.06a
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• pp.46-47
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• 2022

항로표지는 등광, 형상, 색채, 음향, 전파 등을 수단으로 선박의 위치, 방향 및 장애물의 위치 등을 알려주는 항해보조시설로 해상교통 환경의 중요한 인프라이다. 해상교통환경은 4차산업혁명에 따라 자율운항선박, 스마트항만 등의 기술개발과 더불어 급격하게 변화 중이다. 그러므로 해상교통환경 변화에 능동적으로 대응하고 해상안전을 확보하기 위해서는 기존의 항로표지 고도화 및 정보협력서비스 제공이 필요하다. 본 연구의 목적은 미래 해상교통 관리를 위한 항로표지의 새로운 서비스 실효성을 확보하기 위해 사용자 대상 요구사항을 평가하는 것이다. 본 연구의 결과를 통해 선박운항자 등 사용자 관점에서 미래 항로표지 서비스의 요구사항을 파악할 수 있는 기초자료로 활용할 수 있을 것으로 기대한다.

• Radiation Oncology Journal
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• v.29 no.2
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• pp.91-98
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• 2011

Purpose: To assess the usefulness of implanted fiducial markers in the setup of hypofractionated radiotherapy for prostate cancer patients by comparing a fiducial marker matched setup with a pelvic bone match. Materials and Methods: Four prostate cancer patients treated with definitive hypofractionated radiotherapy between September 2009 and August 2010 were enrolled in this study. Three gold fiducial markers were implanted into the prostate and through the rectum under ultrasound guidance around a week before radiotherapy. Glycerin enemas were given prior to each radiotherapy planning CT and every radiotherapy session. Hypofractionated radiotherapy was planned for a total dose of 59.5 Gy in daily 3.5 Gy with using the Novalis system. Orthogonal kV X-rays were taken before radiotherapy. Treatment positions were adjusted according to the results from the fusion of the fiducial markers on digitally reconstructed radiographs of a radiotherapy plan with those on orthogonal kV X-rays. When the difference in the coordinates from the fiducial marker fusion was less than 1 mm, the patient position was approved for radiotherapy. A virtual bone matching was carried out at the fiducial marker matched position, and then a setup difference between the fiducial marker matching and bone matching was evaluated. Results: Three patients received a planned 17-fractionated radiotherapy and the rest underwent 16 fractionations. The setup error of the fiducial marker matching was $0.94{\pm}0.62$ mm (range, 0.09 to 3.01 mm; median, 0.81 mm), and the means of the lateral, craniocaudal, and anteroposterior errors were $0.39{\pm}0.34$ mm, $0.46{\pm}0.34$ mm, and $0.57{\pm}0.59$ mm, respectively. The setup error of the pelvic bony matching was $3.15{\pm}2.03$ mm (range, 0.25 to 8.23 mm; median, 2.95 mm), and the error of craniocaudal direction ($2.29{\pm}1.95$ mm) was significantly larger than those of anteroposterior ($1.73{\pm}1.31$ mm) and lateral directions ($0.45{\pm}0.37$ mm), respectively (p<0.05). Incidences of over 3 mm and 5 mm in setup difference among the fractionations were 1.5% and 0% in the fiducial marker matching, respectively, and 49.3% and 17.9% in the pelvic bone matching, respectively. Conclusion: The more precise setup of hypofractionated radiotherapy for prostate cancer patients is feasible with the implanted fiducial marker matching compared with the pelvic bony matching. Therefore, a less marginal expansion of planning target volume produces less radiation exposure to adjacent normal tissues, which could ultimately make hypofractionated radiotherapy safer.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2010.04a
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• pp.473-480
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• 2010

A key objective is to meet the requirements for safe marine transport and protection of the marine environment by providing a comprehensive mix of Aids to Navigation commensurate with the amount of traffic and the degree of risk. The development of e-Navigation is driven by the compelling need to equip the master of a vessel and those ashore responsible for the safety of shipping with modem, proven tools to improve the reliability of marine navigation and communications. Although position fixing using GNSS is widely used, radar and visual AtoNs continue to be needed to provide safe, secure and environmentally clean navigation. The paper considers the role, evolution and future provision of traditional aids to navigation in an e-Navigation environment from both a technical and mariner perspective.

• The Journal of Korean Society for Radiation Therapy
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• v.33
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• pp.99-108
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• 2021

Purpose: The goal of this study is to evaluate usefulness of noninvasive method instead of previous inserting Fiducial Marker Method when performing Stereotactic Partial Breast Irradiation in CyberKnife. Material and methods: For consistency of Imaging Center, we evaluated both oblique images at angle 45 and 315 acquired from 2D Simulator and CyberKnife quantitatively through dice similarity coefficient. Also, location reproducibility of Surface Fiducial Marker was analyzed from 2D Simulator, treatment plans and CyberKinfe images by using 8 Fiducial Markers made of gold attached to ATOM Phantom based on our institution's protocols. Results: The results of the estimated consistency were 0.87 and 0.9 at the oblique angle 45 and 315, respectively. For location consistency of Surface Fiducial Markers, values of horizontal vertical direction of left breast were Superior/Inferior 0.3 mm, Left/Right -0.3 mm, Anterior/Posterior 0.4 mm, and the values of rotational direction were Roll 0.3 °, Pitch 0.2 °, Yaw 0.4 °. The values of horizontal vertical direction of right breast were Superior/Inferior -0.1 mm, Left/Right -0.1 mm, Anterior/Posterior -0.1 mm, and the values of rotational direction were Roll 0.2°, Pitch 0.1°, Yaw 0.1°. Conclusions: We expect that the protocols used by Surface Fiducial Markers when performing Stereotactic Partial Breast Irradiation in CyberKnife will provide protection from pain and cut expenses for treatment and reduce treatment errors and make treatment more accurate by suggesting treatment protocols based on high consistency of Imaging Center and reproducibility of Fiducial Markers.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.2
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• pp.297-306
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• 2022

AtoN is an acronym for aids to navigation that indicate the position or direction of navigable areas and obstructions. AtoN should be arranged in consideration of unfamiliar navigator's convenience when it is indicated as the limits of navigable areas. Several narrow channels exist on the SW coast of Korea owing to the geographical effect, and the lateral or cardinal marks by the IALA maritime buoyage system are arranged along the narrow channels. This is an actual case study that analyzed the AtoN's role for safety navigation after changes in the maritime traffic environment owing to aquarfarm's development on narrow channels in the Korean SW coast. The analysis results of 5 narrow channels indicated that certain marks did not function properly as lateral or cardinal marks owing to the aquarfarm's location on navigable areas. Therefore, the following were suggested to improve AtoN on narrow channels: changing the position of marks, installing aquafarm's marks, and expressing the aquafarm's position on the nautical chart.

• Journal of Navigation and Port Research
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• v.43 no.4
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• pp.243-249
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• 2019

Seonhwa Bongsa Goryeodogyeong written by Seogeung of Song nationality is the most vivid record of sailing in the West Sea of Goryeo. Seogeung who visited Goryeo on a ship sailed from Heuksando to Byeokrando using a fire signal of the islands area. Fire signal was installed in the Goryeo area, was located nearby the sea route at that time, and was marked by smoke during the day and torched at night so that the navigators could identify it 24 hours. In addition, it was installed at the top of the mountain so that the navigators could easily identify it from a distance. Goryeo fire signal is satisfied by qualification of modern aids to navigation and Visual range is checked about 29-39 miles, Luminous intensity of fire signal estimates to approximately 9,105-168,610cd. Therefore, the fire signal of Goryeo was very easy to use and was highly reliable as operated by the nation and its role in aiding navigations facility as an essential for safe navigation.

• The Journal of the Korean bone and joint tumor society
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• v.13 no.2
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• pp.67-74
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• 2007

Purpose: To evaluate association of giant cell tumors recurrence between markers of proliferation cells (MCM3, Ki-67 and HH3) Materials and Methods: Ten case of giant cell tumor of bone were reviewed. The patients were six males and four females (mean age: 33 yrs). All patients were done operation after biopsy. The radiologic grading was determined according to Enneking grading system. The immunohistochemical stains of MCM3, HH3, and Ki-67 were done with Microarray block. Results: The three cases of 10 cases (30%) were recurred at same sites. Two case of recurrence was grade II according to radiologic features. The remaining case was grade I. The expression rate of immunohistochemical markers in radiologic grade 2 and 3 were more increased than grade 1. But there was not association between radiologic grading and proliferation of tumor cells because result data was not coherence. Mean MCM3 labeling index of non-recurred case was 11.2%, recurred case was 7.2%. Ki-67 was 12% vs. 8.9%, respectively and HH3 was 66.9 % vs. 75.4%, respectively. Thus there was no association between local recurrence and immunohistochemical Ki-67, MCM3 expression rate. But HH3 marker expression rate was increased in recurred cases compared to non-recurred cases. Conclusion: Our study suggests that HH3 immunohistochemical marker can be a useful prognostic factor.

• Journal of Korean Society of Forest Science
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• v.87 no.3
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• pp.422-428
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• 1998

Polymerase chain reaction(PCR)-based inter-simple sequence repeats(I-SSR) markers were analyzed in 48 megagametophytes of a single tree of Abies koreana $W_{ILS}$. Nineteen of the 35 primers, screened with 6 megagametophyte DNA and produced the clearest amplification products in the preliminary experiment, were used for PCR with 48 megagametophyte DNAs sampled from a single tree. On the basis of the chi-square test, a total of 51 amplicons, amplified by the 19 primers, were revealed to be segregated according to the Mendelian ratio(i.e., 1 : 1 segregation ratio) in the 48 megagametophytes at 5% significance level. Based on the linkage analysis, the observed 51 Mendelian loci turned out to be unlinked each other, which suggested that they are evenly distributed in the genome. However, majority of RAPD markers are known to belong to the independent linkage blocks, which frequently results in the amplification of RAPD markers from the restricted regions of the genome. Owing to the nature of even distribution of the 51 loci observed in this study, the I-SSR markers could give better resolution of estimating genetic diversity from the whole genome than RAPD markers. And I-SSR markers are also more suitable than RAPD markers for reconstructing phylogenetic relationship by a cladistic method which requires to fulfil the assumption of independent evolution of the different characters.