• Korean Journal of Head & Neck Oncology
• /
• v.14 no.2
• /
• pp.244-252
• /
• 1998

The thyroid nodules are the most common endocrine disease requiring surgical management. We perfomed a clinical study of 298 cases with thyroid nodules, who were admitted to and operated at the Department of Surgery, College of Medicine, Gyeong sang National University from January 1987 to April 1997 and the results were summarized as follows: 1) Patients were composed of 214 cases(71.8%) of benign nodule and 84 cases(28.2%) of malignant nodule. Benign and malignant nodules were prevalent in fifth decade. 2) The sex distribution showed a preponderance of females with ratio of 5.88:1 in benign nodule and 11:1 in malignant nodule. 3) The nodules were located in the right lobe(134 cases, 44.9%), the left lobe(121 cases, 40.6%), both lobes(34 cases, 11.4%), and isthmus(8 cases, 2.7%). The possibility of malignancy was higher in the solid rather than cystic lesions. 4) Radioactive iodine scintiscans were perfomed in 273 cases and revealed cold nodules in 237 cases(86.8%), 58 of these cases(24.4%) were malignant. 5) According to the histopathologic classification, benign nodules included follicular adenomas 136 cases(63.5%), adenomatous goiters 67 cases(31.3%), Hurthle cell adenomas 4 cases(1.9%), cysts 3 cases(1.4%) and thyroiditis 4 cases(1.4%). In malignant nodules, papillary carcinomas 72 cases(85.7%), follicular carcinoma 8 cases(9.5%), undifferentiated carcinoma 2 cases(2.4%), medullary carcinoma 1 case(1.2%) and malignant lymphoma 1 case(1.2%). 6) The most commonly performed operative procedure was a lobectomy with isthmusectomy(85.5%) for bengn nodules and a total thyroidectomy(51.2%) for malignant nodules. 7) The rate of complications was higher in the cases with malignant nodules(20.2%) than in the benign cases(0.5%). The recurrence rate was 8.3%(7 cases).

• Journal of Food Hygiene and Safety
• /
• v.31 no.5
• /
• pp.356-364
• /
• 2016

In vivo genotoxic potential of isoquercetin, a plant common flavonoid, in comparison with quercetin was investigated for the DNA breakage and the clastogenicity endpoints. Male ICR mice were administered by oral gavage for 3 days with $3{\times}0.5%$ carboxymethyl cellulose (CMC), 3 ${\times}$ isoquercetin (250, 500 mg/kg/day), 3 ${\times}$ quercetin (250, 500 mg/kg/day) and 2 ${\times}$ ethyl methanesulfonate (EMS, 200 mg/kg/day). Tissues were collected 48 hours after the first treatment and within 3 hours after the last treatment. The DNA damages were evaluated using Comet assay in liver and stomach, while the clastogenicities were determined using micronucleus test in bone marrow of same animals. The treatment of isoquercetin as well as quercetin did not cause the DNA damages in liver and stomach, and not induce the frequencies of micronucleus polychromatic erythrocytes in bone marrow. In conclusion, isoquercetin as well as quercetin did not cause the DNA breakages and the chromosomal damages in vivo system in these study conditions.

• Journal of Chest Surgery
• /
• v.31 no.3
• /
• pp.324-328
• /
• 1998

Esophageal hemangioma is an extremely rare benign tumor that causes dysphagia and massive upper gastrointestinal bleeding. Although certain abnormalities seen on a barium swallow esophagography or at endoscopy may suggest an esophageal hemangioma, a contrast CT and radionuclide angiography using a blood-pool radiopharmaceutical can characterize the intense vascularity of the tumor. We experienced the ase of a 7$\times$7$\times$3.5 cm in size giant cavernous hemangioma of the lower 1/3 of esophagus in a 40 year old man. A mural cavernous hemangioma was diagnosed with a barium swallowed esophagogaphy, endoscopy, and a contrast CT. It was treated successfully by transthoracic esophagectomy including the tumor and esophagogastrostomy.

• KIISE Transactions on Computing Practices
• /
• v.23 no.9
• /
• pp.557-563
• /
• 2017

When large-scale gene expression data are analyzed using lasso regression, the estimation of regression coefficients may be unstable due to the highly correlated expression values between associated genes. This irregularity, in which the coefficients are reduced by L1 regularization, causes difficulty in variable selection. To address this problem, we propose a regression model which exploits the repetitive bootstrapping of gene expression values prior to lasso regression. The genes selected with high frequency were used to build each regression model. Our experimental results show that several genes were consistently selected in all regression models and we verified that these genes were not false positives. We also identified that the sign distribution of the regression coefficients of the selected genes from each model was correlated to the real dependent variables.

• Journal of Korea Multimedia Society
• /
• v.13 no.11
• /
• pp.1698-1705
• /
• 2010

In this paper, we propose a fast liver segmentation method from magnetic resonance(MR) images. Our method efficiently divides a MR image into a set of discrete objects, and boundaries based on the normalized gradient magnitude information. Then, the objects belonging to the liver are detected by using 2D seeded region growing with seed points, which are extracted from the segmented liver region of the slice immediately above or below the current slice. Finally, rolling ball algorithm, and connected component analysis minimizes false positive error near the liver boundaries. Our method was validated by twenty data sets and the results were compared with the manually segmented result. The average volumetric overlap error was 5.2%, and average absolute volumetric measurement error was 1.9%. The average processing time for segmenting one data set was about three seconds. Our method could be used for computer-aided liver diagnosis, which requires a fast and accurate segmentation of liver.

• Clinical and Experimental Pediatrics
• /
• v.52 no.2
• /
• pp.251-255
• /
• 2009

Kawasaki disease is an acute systemic inflammatory disorder, the etiology of which has not yet been established. The clinical manifestations are non-specific and are common to many pediatric infectious and immunologic diseases. In 2 cases presenting fever, cervical lymphadenopathy, and retropharyngeal abscess-like lesions on the neck shown in a computerized tomography (CT) scan, the diagnosis of Kawasaki disease was delayed. The patients were not responsive to antibiotic therapy, and fluid collection was not found during retropharyngeal aspiration. They showed typical Kawasaki manifestations over time and atrioventricular valve regurgitation in the echocardiogram. A diagnosis of Kawasaki disease should be considered in similar cases of fever and cervical lymphadenopathy. A CT scan that shows a retropharyngeal abscess-like lesion on the neck can be a false positive finding, and other laboratory exams, including echocardiography, should be performed as early as possible to avoid unnecessary medical and surgical procedures.

• The Inventors News
• /
• no.55
• /
• pp.1-16
• /
• 2007

선진국가 선도하는 창의적 여성경제리더 양성하자/발명지도사.시제품제작지원 시행/발행인 칼럼/특허심사처리 세계에서 가장 빠르다/글로벌 기업, 한국 특허청에 심사의뢰 쇄도/국유특허권 온라인 전자계약 시행/특허기술, "기술경매" 로 산다/여성발명인 거유 활동 영역 넓어/감귤와인 특허획득 이어 독일 등 해외 수출 기대/미더덕 냉동 않고도 장기 보관/특허민원서식 대폭 감축/특허청, 개도국 지원사업 대폭 확대/기상청, 날씨예보기술로 특허 받아/우리나라 국제특허출원 수준 세계 6위/건강관련 브랜드 상표출원 증가/친환경수로관 '도룡용 살린다'/고등학교에 첫 발명창작과 개설/욕조, 웰빙 휴식공간으로 자리매김/가습기, 공기정화.탈취.방향 등 다기능화/패치제 특허출원 해마다 증가/일 특허청, 분할출원기간 30일 연장/중 법원, 비아그라 특허군 인정/국내 제약사 유유 "미머크사 특허 침해" 주장/삼성전자, 지난해 미 특허 2천4백53건으로 2위/기업심볼마크는 단순, 상표는 길어져/LG전자 "대우일렉이 드럼세탁기 특허권 침해했다"/유.무선 통합 '원폰 서비스' 기술 개발/암환자 울린 과대광고제품 1백억원대 판매 적발/맥도날드 '해피밀' 광고 퇴출/세원셀론텍, 콜라겐 원천기술 특허/역사 속의 발명품/하루 10분 발명교실/특허Q&A/'S&D Trecap' 황지경 대표/경기도, 여성분야 소상공인창업자금 신설/특허청, 세계지식재산기구(WIPO) 진출확대/아이디어 착상 및 발명 기법/여성발명 활성화만이 국가경쟁력 키우는 첩경/히로자키의 광엽수 진액/해외 네티즌 인기 화제의 발명품들/여성기업 생산제품 MAS시 적격성 평가 면제/특허청, 시작품제작지원 5천만원까지 확대/지난해 짝파라치에게 3억2천3백만원 포상금 지급/입체방송 분야 특허출원 봇물/트랜스지방 퇴출 시민단체 '토트랜스 클럽' 출현/한국여성발명협회 회원사 발명품 가이드/

• Journal of the Korean Data and Information Science Society
• /
• v.26 no.3
• /
• pp.611-618
• /
• 2015

By Wikipedia, big data is a broad term for data sets so large or complex that traditional data processing applications are inadequate. Data mining is the computational process of discovering patterns in huge data sets involving methods at the intersection of association rule, decision tree, clustering, artificial intelligence, machine learning. Association rule is a well researched method for discovering interesting relationships between itemsets in huge databases and has been applied in various fields. There are positive, negative, and inverse association rules according to the direction of association. If you want to set the evaluation criteria of association rule, it may be desirable to consider three types of association rules at the same time. To this end, we proposed a balanced comparative confidence considering sensitivity, specificity, false positive, and false negative, checked the conditions for association threshold by Piatetsky-Shapiro, and compared it with comparative confidence and inversely comparative confidence through a few experiments.

• Journal of the Korean Chemical Society
• /
• v.35 no.2
• /
• pp.158-164
• /
• 1991

The reduction mechanism at a mercury electrode of o-cresolphthalexon(OCP) in strongly alkaline supporting electrolytes has been investigated by several electrochemical techniques. The radical formed after first one electron reduction uptake, dimerizes. The result of cyclic voltammetric investigation demonstrated the reversible nature of the electron transfer and standard rate constant was $3.27{\times}10^{-2}$ cm/sec. The apparent irreversible behavior of the second wave is a result of the existence of a fast protonation following the second electron transfer. At low concentration of OCP(< $1{\times}10^{-4}$M), cathodic current were remarkably adsorptive properties. Prolonged electrolysis was carried out at controlled potential of -1.85V, original violet color of the solution becames progressively weaker, and then colorless solution. The final product of an exhaustive electrolysis is electro-inactive. The appearence of four steps may be explained by the fact that the reduction of OCP elucidated ECEC mechanism.

• Journal of Korean Society for Geospatial Information Science
• /
• v.21 no.3
• /
• pp.47-54
• /
• 2013

Real estate development promotes the efficient management of the land and has immense impact on national economy. So, it is necessary to establish a comprehensive policy by accumulating related information. Real estate development map must have the information about a parcel and adjacent parcel to make it possible to analysis in spatial domain, because error will be manifested in analysis using only real estate attribute information. This can be allocate the attribute of public management information about real estate on cadastral information and spatial information for social infrastructure and buildings. Especially, it must maintain the latest information of changes in the shape and the attributes of the buildings. This study suggested a method for developing a real estate development map based on road name address map and a method to maintain the latest information through the connection with related systems.