• Journal of The Korean Association For Science Education
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• v.35 no.6
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• pp.1049-1062
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• 2015

To understand the synergy of collaboration and to apply this understanding to education, an analysis of how a team solves a problem and the sharing of their mental models is needed. This paper analyzed two things qualitatively to find out the source of synergy in a collaborative problem-solving process. First, the sharing contents in team mental model and second, the process of sharing the team mental model. Ten gifted middle school students collaborated to solve an ill-defined problem called sunshine through foliage problem. The gifted students shared the following results after the collaboration: First, scientific concept prior to common idea or the idea that all group members have before the discussions; second, unique individual ideas of group members; and third, created ideas that were not originally in the personal mental model. With created ideas, the team model becomes more than the sum of individuals. According to the results of process analysis, in the process of sharing mental model, the students proposed and shared the most important variable first. This result implied that the analysis of the order of sharing ideas is important as much as finding shared ideas. Also, the result shows that through their collaboration, the gifted students' shared mental model became more refined and expanded as compared to their individual prior mental models. It is recommended that these results can be used to measure shared mental model and develop collaborative learning models for students.

• Journal of Food Hygiene and Safety
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• v.31 no.4
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• pp.294-298
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• 2016

Natural products are attractive as the source of new drug development. Especially, numerous unknown marine bioresources are an object of attention because the ocean occupies three fourth of the earth. Survival of marine bioresources in extreme environment may induce the production of biological active compounds. As previous study, we examined over 40 specimens of marine sponges collected from Micronesia and screened their anti-proliferative activities in various cancer cell lines. Among them, we investigated Coscinoderma sp.'s activity and mechanism in human colon carcinoma HCT116 and RKO cells. Furthermore, we also used the p53-knockout of HCT116 cells and the p53 loss of RKO cells for elucidating the role of p53. Coscinoderma sp. inhibited cellular viability independently of the p53 status. Therefore, we compared the expression level of cell death-related proteins by Coscinoderma sp. in HCT16 and in HCT116 p53KO cells. Coscinoderma sp. increased p53 level and NOXA levels and induced apoptosis under the condition of p53 existence. On the other hand, Coscinoderma sp. increased p21 and mTOR levels in HCT116 p53KO cells. These results suggest that Coscinoderma sp. induced anti-proliferation effect through different pathway depending on p53 status.

• Journal of vocational education research
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• v.36 no.4
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• pp.1-20
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• 2017

The purpose of this study is to identify the cognitive and psychological precedence factors of career preparation behaviors of university students and to clarify the structural relationships between the variables. First, the effects of reflective learning on university students' career preparation behaviors were examined and the mediating effect of grit between reflective learning and career preparation behavior was verified. The research analyzed 307 university students in the 3rd and 4th year. The results of the study have shown that the reflective learning had a significant positive relationship with all variables of grit and career preparation behavior, but non-reflective learning have an insignificance relationship with all the main variables. In addition, reflective learning has a direct positive effect on career preparation behavior, and grit has a mediating effect on the relationship between reflective learning and career preparation behavior. The results of this study indicate that the more original variables are further identified and extended to improve career preparation behaviors of university students. It is significant that they are provided with the basic data for the development of career and job preparation education programs that can be applied in the university education field. In addition, it has been confirmed that it is important for university students to improve their ability to critically reflect on themselves, their surroundings and circumstances in order to keep them engaged and to maintain their interests. Moreover, higher education institutions should provide fundamental and extensible method of practice and educational environment.

• Journal of Life Science
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• v.32 no.7
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• pp.550-566
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• 2022

Stroke is among the leading causes of death and long-term physical and cognitive disabilities worldwide, affecting an estimated 15 million people annually. The pathophysiological process of stroke is complicated by multiple and coordinated events. The breakdown of the blood-brain barrier (BBB) in people with stroke can significantly contribute to the development of ischemic brain injury. Therefore, BBB disruption is recognized as a hallmark of stroke; thus, it is important to develop novel therapeutic strategies that can protect against BBB dysfunction in ischemic stroke. Traditional medicines are composed of natural products, which represent a promising source of new ingredients for the development of conventional medicines. Indeed, several studies have shown the effectiveness of Korean medicine on stroke, highlighting the value of Korean medicinal treatment for ischemic stroke. This review summarizes the current information and underlying mechanisms regarding the ameliorating effects of the formula, decoction, herbs, and active components of traditional Korean medicine on cerebral ischemia-induced BBB disruption. These traditional medicines were shown to have protective effects on the BBB in many cellular and animal ischemia models of stroke, and experiments in various animal species, such as mice and rats. In addition, they showed brain-protective effects by protecting the BBB through the regulation of tight junction proteins and matrix metalloproteinase-9, reducing edema, neuroinflammation, and neuronal cell death. We hope that this review will help promote further investigation into the neuroprotective effects of traditional Korean medicines and stimulate the performance of clinical trials on Korean herbal medicine-derived drugs in patients with stroke.

• Analyses & Alternatives
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• v.6 no.2
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• pp.117-154
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• 2022

The purpose of this study is to verify the practical validity of financial sanctions, which has recently emerged as the most powerful form of economic sanctions preferred by U.S. foreign policy tool. Based on the theoretical discussion, analyse this study the trend of de-dollarization appearing in connection with financial sanctions and argue that the effectiveness of financial sanctions erode the dollar financial hegemony, which is the source of its power can be degraded, so that its effectiveness could not be so great as most people likely think about. After World War II, there has been an increasing tendency in the international community to favor economic sanctions over the use of military force as an effective means of foreign policy. Among these economic sanctions, a distinct feature that has recently appeared is the remarkable increase in the frequency of use of financial sanctions. The country that favors financial sanctions most is the United States. The reason is that they believe that the power of their own dollar financial hegemony can exert deadly pressure on other countries. Financial sanctions favored by the United States are said to have increased the effectiveness of sanctions by upgrading the pressure of sanctions to the next level. Nevertheless, financial sanctions have a side that underestimates the cost. This problem is found in the signs that the backlash from not only countries subject to financial sanctions but also many countries with interests in these countries is leading to a tendency to de-dollarization. This study will try to see how likely this de-dollarization trend is to offset the effectiveness of financial sanctions.

• Information Systems Review
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• v.13 no.3
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• pp.27-46
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• 2011

Many business managers claim that treasury management is their leading concern. Managing cash flows is the center of treasury management. However, in reality, companies has experienced the difficulty in monitoring and controling this flow initiated by business transactions. To resolve this problem, Webcash Inc. developed an innovative systems called Branch Solution. Branch Solution stands in between banking systems and a company's ERP system to connect them. This system provides the company with an ability to control the financial flow in accordance with the physical flow of materials. Due to this solution many companies accomplish a high efficiency and visibility in their cash management. This study analyses a treasury management case from the perspective of supply-chain processes integration.

• Journal of Digital Contents Society
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• v.14 no.4
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• pp.481-491
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• 2013

This paper is introducing on a strategy of storytelling which is utilized as a core skill in developing cultural contents. The proposed storytelling method consists of three steps(planning, production, editing). The method of storytelling strategy is based on rhetoric metaphors and classifies rhetoric metaphors into three kinds of image metaphor, image personification and image simile. This thesis produced and studied 3 visual-image contents including 1 metaphor, 1 personification and 1 simile. As a result, visual-image contents can be a resonable method of the communicational act of visual-image contents with a rhetoric expression. This result will contribute to recognize the possibility of expressing visual-image contents by various figure. Recently, there are a lot of concernments on the expression by creative visual-image contents, but a theoretical study on creative idea for visual-image contents is insufficient. So, in the future, this thesis will be used for basic materials to express a creative visual-image contents, and also contribute to offering basic theories for visual-image contents study and teaching.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.302-308
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• 2020

This study investigated when TV drama producers choose famous actor/actress based on 288 TV dramas aired in Korea from January 2014 to December 2017. We considered the length of drama, measured by the number of episodes, as a major determinant for choosing famous actor/actress, as well as the existence of originals, use of independent producing agents, and producers' fame as interacting factors between length of drama and choosing famous actor/actress. We detected that drama length had a significant effect while original dramas had an interacting effect. We interpret this result as the effect of mismanagement of drama producing. While a famous actor/actress has the potential to provide economic gains to drama producers, drama producers should be careful in choosing him/her since his/her drama guarantee should be high. This is why producers should choose a famous actor/actress when the length of the drama is short and should prefer an original drama.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2017.04a
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• pp.43-43
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• 2017

종자산업은 농작물 생산에 중요한 역할을 끼치는 좌우하는 요소 중에 하나로, 우량종자의 확보는 농작물 수급에 중요한 역할을 하는 농업부문의 원천산업이다. 오이 녹반 모자이크 바이러스(CGMMV)는 박과류에 가장 많은 피해를 끼치는 바이러스로 종자전염을 방지하고, 우량종자의 공급을 위해서는 감염종자와 비 감염종자의 판별은 필수적이다. 이에 본 연구에서는 초분광 영상 시스템을 이용하여 수박종자의 CGMMV의 감염 및 비 감염종자를 판별할 수 있는 기술을 개발하고자 하였다. 본 연구에서 사용된 바이러스 감염 종자는 CGMMV 바이러스 감염 수박종자를 사용하였으며, 생산된 종자를 초분광 영상 시스템을 통해 스크린 후, RNA를 추출하여 PCR분석법으로 바이러스의 감염유무를 확인하였으며, 이후 바이러스의 감염유무와 획득된 스펙트럼을 비교 분석하여 판별모델을 개발하고 이를 선별 시스템에 적용하였다. 모델개발에 사용된 초분광 영상 기술은 초분광 SWIR(Shortwave infraed : 1000-2500nm)영상 기술이 다. 획득된 초분광 SWIR 영상을 분석한 결과 바이러스 감염 종자가 유의미한 정확도로 판별이 되는 것으로 나타났다. 초분광 SWIR 영상기술이 바이러스 감염종자와 비감염종자를 비파괴적으로 선별하는데 효과적으로 적용이 가능할 것으로 판단된다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.6
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• pp.1387-1394
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• 2015

Recently, there is a growing interest in technical standardization all over industry, it is very important for survival in the global market to secure standard patent in almost all of company. Technology in construction industry is essential for quality of people's life and have large impact on national economy development. However, there is lack of investment and low interest in technical standardization in construction industry in comparison with another industries. Therefore this study aims at developing strategies for activating the standardization in construcion technology. Specially, this study carries market analysis and case study for domestic construction R&D Cases. Then, a structured survey and analysis is performed for standardization in construcion technology market to suggest alternative to secure national competitiveness.