• Journal of the Korea Organic Resources Recycling Association
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• v.20 no.2
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• pp.15-19
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• 2012

Wood wastes could be renewable resources by recycling as particleboard manufacturing or energy production. Particle board is the most common item of wood waste recycling and energy production from wood wastes has highlighted for energy recovery to reduce greenhouse gas generation in recent years. The aim of this study was to evaluate the environmental benefits of the processes for particle board manufacturing and energy production. The functional unit was one ton of wood wastes and the environmental impact was analyzed by life cycle assessment methodology. The result was that 112kg of carbon dioxide equivalent was produced from particle board manufacturing process and 382kg of carbon dioxide equivalent was produced from combined heat and power generation process. The concept of temporary biomass carbon storage was to applied to this study.

• Food preservation and processing industry
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• v.7 no.2
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• pp.2-2
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• 2008

발효는 인류의 역사와 함께 해 왔으며 과학 기술발전에 따라 자연 발효에서 관리하는 방법으로 급격히 변하고 있다. 발효는 미생물과 미생물이 생산한 효소의 작용으로 일어나는바 미생물 관리를 통하여 실로 다양한 제품 생산이 가능하고 역할의 범위도 지극히 넓다. 즉 원하는 최종 제품의 종류에 따라 미생물을 선택하거나 발효조건을 관리하여 목적 지향적 완제품 생산이 가능한 경우가 많다. 한국인의 식단을 이루는 기본은 각종 발효 제품을 근간으로 하는 조미료이며, 조미료에 따라 맛의 변화가 온다. 발효를 통하여 소화성의 증대, 비타민 등 새로운 미량물질의 생산, 풍미의 개선 혹은 새롭게 창조하거나 저장기간을 연장하기도 하며, 사용하는 원료와는 완전히 다른 신제품을 만들어 내기도 한다. 근래의 연구 결과들을 살펴보면 여러 기능성 물질이 발효를 통하여 생성되며 이들이 인체 내에서 긍정적 역활을 한다는 것이 밝혀지고 있다. 전통식품 중 발효식품은 가장 큰 비중을 차지하며 곡류 중심의 식단에 맛을 부여하여 먹는 즐거움을 주고 전망있는 다른 산업으로 발전 해 나갈 수 있는 특성이 있다. 발효식품은 다양한 원료를 사용 할 수 있고 원료에 따라 많은 서로 다른 제품생산이 가능하다. 우리나라에서 생산되는 주요 발효식품은 김치를 포함한 절임류, 곡물 또는 과실을 이용한 주류, 어류로 각종 젓갈을 만들 수 있으며 근래 수요가 늘고 있는 요구르트 등도 인기 있는 발효식품이다. 특히 발효식품에 관여하는 미생물들이 probiotic으로 작용하여 장내 미생물의 항산성 유지 및 유해 세균의 증식억제 등 긍정적 역할을 하며 우유 발효균으로 알려진 젖산균류 뿐만 아니라 다른 세균들도 probiotic으로 작용한다는 것이 밝혀지고 있으며, 특히 장류에 많이 관여하는 Bacillus 속 들의 긍정적 역할이 속속 알려지고 있다. 또한 발효를 통하여prebiotic도 만들어지는 것을 알 수 있다. 앞으로 발효식품의 기능성의 과학적 입증 발효의 과학적 관리, 제품의 다양화와 함께 안전성도 검토할 대상이다. 또한 심도있게 발효 관여 미생물을 탐색, 동동하고 발효기반의 이용확대, 맞춤형 특수 미생물의 탐색과 용도 확인 등 노력이 필요하다. 우리나라 전통식품 중 큰 비중을 차지하는 발효식품을 세계화하기 위해서는 건강기능성의 과학적 기반 구축과 전문 학술 활동을 통한 홍보, 현지 식품에 맞는 fusion food의 개발도 필요하다. 발효식품을 포함한 전통식품은 경제적 측면과 함께 문화적 가치가 동시에 고려되어야 하고 다문화 추세에 따라 유연성 있게 변화를 수용 할 필요도 있다. 전통 발효식품을 우리 식문화를 세계에 전파시키는 좋은 매체로 활용 할 수 있을 것이다.

• Korean Chemical Engineering Research
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• v.53 no.3
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• pp.339-349
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• 2015

In this work, DAY (Dealuminated Y-type) zeolites were prepared to be used as easily regenerable and thermally stable adsorbent substituting activated carbon. NaY zeolites were transformed into DAY zeolites through ion exchange, calcination, steaming, and acid leaching. Calcination temperature and time, and steaming time were changed to increase the Si/Al ratio and maintain crystallinity. Adsorption of VOCs were done for prepared DAY, commercial NaY and Hisiv 1000 in air with relative humidity of 50%. The DAY zeolite prepared by calcination at $520^{\circ}C$ for 4 hrs and steaming for 7 hrs had a same structure and a Si/Al ratio of 80.4. Its adsorption capacity for water vapor was 10% of NaY, indicating its hydrophobicity. Its adsorption capacity for MEK was 0.8 times of Hisiv 1000, that for toluene 1.6 times, and that for EA 1.3 times.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2017.05a
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• pp.433-439
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• 2017

This research investigates the manufacturing process and characteristics analysis of $BKNO_3$ (Boron Potassium Nitrate) as pyrotechnic are commonly found in the aerospace, defense, and automotive industries. A solid pyrotechnic mixture is composed of an oxidizing agent, fuel, and binder. Precipitation process was used to uniformly mix the raw material. Through the analysis of the material characteristics and thermal response is designed optimum ratio by NASA CEA program. It was compared by performing the evaluation of these size/shape/sensitivity/calorimetry characteristics.

• Journal of Convergence for Information Technology
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• v.12 no.1
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• pp.144-152
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• 2022

The Spartina anglica is recognized as a highly invasive plant and active eradication methods are required. In this study, we aimed to determine the physiologic activities of Spartina anglica extracts as a cosmetic ingredient. Antioxidant properties were investigated by different chemical methods including radical quenching (DPPH and ABTS), reducing power(FRAP) assay and aerial part of S. anglica(SAA) extract presented the strongest antioxidant activities. The significant cytotoxicity was not observed up to a concentration of 0.5 mg/mL in RAW264.7 cells and NHDF cells. The anti-inflammatory activity of S. anglica belowground(SAB) extract had strong effects on cell-based systems, including LPS-induced NO and cytokines(TNF-a and IL-6) production in RAW264.7 cells. Collagen synthesis and skin hydration gene expression of S. anglica extract showed the highest anti-wrinkle and moisturizing effect in NHDF cells. Results presented in this study tend to show that the ethanol extracts of S. anglica could be exploited as useful-bio-resource for bioactive substances in functional cosmetics.

• Korean Chemical Engineering Research
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• v.54 no.2
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• pp.278-283
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• 2016

In this study, we have for the first time applied fractional precipitation with hydrophilic polymer in order to decrease the particle size of the anticancer agent paclitaxel from plant cell cultures. When compared with the case where no hydrophilic polymer was employed, the addition of hydrophilic polymer in fractional precipitation resulted in a decrease in the size of the paclitaxel precipitate. Among the polymers used, HPMC 2910 was the most effective for inhibition of precipitate growth. A polymer concentration of 0.2% (w/v) obtained the smallest particle size. The particle size was reduced by ~35% compared to control. In addition, the precipitate size was inversely correlated with the absolute value of the zeta potential.

• 월간산업보건
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• s.42
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• pp.25-28
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• 1991

산업현장에서는 대단히 많은 화학물질이 원료, 기타 용도로 이용되고 있으며, 근로자는 항상 폭로 내지는 중독의 위험을 받고 있다. 따라서 그 관리를 함에 있어서는 산업에서 쓰이는 화학물질의 종류와 양, 사용공정, 근로자의 폭로 상황에서부터 폐기에 이르기까지 모든것을 파악함과 동시에 그 작업환경관리, 작업관리 및 건강관리에 관해서 법규나 실제를 상세하게 알아둘 필요가 있다. 1. 관리는 기본적으로 법규에 의거하여 실시되는데, 여기에는 최소한의 규칙이 있으며, 실제 관리에 있어서는 임기응변의 최대한 노력이 필요하다. 2. 환경관리를 하는데는 기본적으로 허용농도가 이용되며, 국제적으로는 생물학적 한계치가 제창되어 응용되고 있다. 3. 법규 또는 독성에 의거하여 특정 화학물질, 기타 각종 호칭이 쓰이고 있으며 이러한 단어는 어떤내용을 지니고 있기 때문에 충분하게 정립해 둘 필요가 있다. 4. 화학물질에 의한 중독예는 해마다 감소되고 있는데 반하여 때로 대참사를 일으키는 수도 많아서 예전부터 화학물질에 의한 급성중독에서부터 만성장기폭로로 인한 영향에 대해 관심을 모으고 있다. 특히 직업성암에 대한 문제가 대두되고 있다. 5. 사고성 대량방출이나 산소 결핍증에는 구조자나 제3자에 대한 이차성 피해가 발생되기 쉬우므로 이 점에 주의를 요한다. 6. 일반환경으로의 방출로 인해 주민에게 미치는 영향도 주의해야 한다. 7. 근로자는 화학물질의 위험성에 대하여 잘 알지 못하거나 습관적인 취급으로 인해 주의가 산만해지기 때문에 충분한 보건교육이 있어야 한다. 8. 화학물질에 의한 건강장해예방의 기본은 발생억제, 격리, 제거(배기), 체내 침입방지, 장해예방(건강진단, 생활 등)이다.

• KSBB Journal
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• v.23 no.4
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• pp.303-310
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• 2008

Bovine blood, cell, tissue, and organ are used as raw materials for manufacturing biologics such as biopharmaceuticals, tissue-engineered products, and cell therapy. Manufacturing processes for the biologics have the risk of viral contamination. Therefore viral validation is essential in ensuring the safety of the products. Bovine parainfluenza virus type 3 (BPIV3) is one of the common bovine pathogens and has widely been known as a contaminant of biologics. In order to establish the validation system for the BPIV3 safety of biologics, a real-time RT-PCR method was developed for quantitative detection of BPIV3 contamination in raw materials, manufacturing processes, and final products. Specific primers for amplification of BPIV3 RNA was selected, and BPIV3 RNA was quantified by use of SYBR Green I. The sensitivity of the assay was calculated to be 2.8 $TCID_{50}/mL$. The real-time RT-PCR method was validated to be reproducible and very specific to BPIV3. The established real-time RT-PCR assay was successfully applied to the validation of Chinese hamster ovary (CHO) cell artificially infected with BPIV3. BPIV3 RNA could be quantified in CHO cell as well as culture supernatant. Also the real-time RT-PCR assay could detect 7.8 $TCID_{50}/mL$ of BPIV3 artificially contaminated in bovine collagen. The overall results indicated that this rapid, specific, sensitive, and robust assay can be reliably used for quantitative detection of BPIV3 contamination during the manufacture of biologics.

• Korean Journal of Microbiology
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• v.44 no.1
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• pp.14-21
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• 2008

Bovine blood, cell, tissue, and organ are used as raw materials for manufacturing biopharmaceuticals, tissue engineered products, and cell therapy. Manufacturing processes for the biologicals using bovine materials have the risk of viral contamination. Therefore viral validation is, essential in ensuring the safety of the products. Bovine herpesvirus type 1 (BHV-1) is the most common bovine pathogen found in bovine blood, cell, tissue, and organ. In order to establish the validation system for the BHV-1 safety of the products, a real-time PCR method was developed for quantitative detection of BHV-1 in raw materials, manufacturing processes, and final products as well as BHV-1 clearance validation. Specific primers for amplification of BHV-1 DNA was selected, and BHV-1 DNA was quantified by use of SYBR Green I. The sensitivity of the assay was calculated to be $2\;TCID_{50}/ml$. The real-time PCR method was validated to be reproducible and very specific to BHV-1. The established real-time PCR assay was successfully applied to the validation of Chinese hamster ovary (CHO) cell artificially infected with BHV-1. BHV-1 DNA could be quantified in CHO cell as well as culture supernatant. Also the real-time PCR assay could detect $10\;TCID_{50}/ml$ of BHV-1 artificially contaminated in bovine collagen. The overall results indicated that this rapid, specific, sensitive, and robust assay can be reliably used for quantitative detection of BHV-1 contamination during the manufacture of biologics.

• KSBB Journal
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• v.23 no.1
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• pp.1-7
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• 2008

The world demand of ethanol as an alternative fuel for gasoline is increasing rapidly because of high oil price and global climate change. Most of ethanol is currently produced from corn grain or sugars in sugarcane and sugar beet. Because these sources compete with foods and animal feed and are not expected to be enough for future demand of ethanol. Thus, cellulosic ethanol from agricultural residues or wood has to be commercialized in near future. Typical cellulosic ethanol production consists of pretreatment, enzyme hydrolysis, fermentation and product separation. This paper reviews the principles and status of each step and discusses issues for cellulosic ethanol production.