• Journal of the Korea Convergence Society
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• v.13 no.1
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• pp.101-107
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• 2022

Tertomotide is a peptide vaccine developed for anti-cancer therapy. Since it has been found to ameliorate inflammatory symptoms in animal studies and clinical test, we investigated anti-inflammation activity of the tertomotide and the mechanism of action in monocyte in order to assess if tertomotide may serve as an anti-inflammatory agent by checking inflammatory cytokines and related signaling pathway following tertomotide treatment. We found that tertomotide reduced the level of pro-inflammatory cytokines such as TNF-α, IL-1β, IL-8 in LPS- or PMA-stimulated monocyte cell line and suppressed NF-κB signaling including the activation of ERK1/2 and P38 MAPK following TNF-α treatment. These results may correlate to the beneficial findings in animal studies, implicating that tertomotide may act as a potential anti-inflammatory agent. This study is an exemplary case for convergence that a computationally designed peptide for immunological purpose exerting unexpected biological activity may elicit novel anti-inflammatory drug.

• Environmental and Resource Economics Review
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• v.13 no.1
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• pp.83-117
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• 2004

This study investigates the spatial distributions of the ambient levels of air pollutants ($SO_2$, $NO_2$, $O_3$, CO, and PM) in Seoul metropolitan area using the data obtained by the air pollution observation stations. This study estimated a non-parametric kernel density function and two types of inequality indices, Gini and Entropy. Our estimation results show that the degree of inequality in spatial distribution of air pollution, in general, tends to be stable or slightly decreasing for the period of 1990~2001. In addition, we found that there are significant dynamics of air pollution levels in terms of spatial ranking.

• KSBB Journal
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• v.4 no.2
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• pp.177-184
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• 1989

In separating mycelia from antibiotic fermentation broths, high permeate flux was obtained by cross-flow filtration using modified regenerated cellulose membrane. The flux was increased most effectively by increasing the flow rate. There existed a critical mycelium density (about 20% PMV) at which the highest flux was observed. In a batchwise concentration of the fermentation broth, the system suffered from a severe fouling problem, which was relieved drastically by applying diafiltration technique, although it increased the permeate volume. A combined concentration/diafiltration process was ideal in keeping relatively high flux together with a high product recovery yield. The best result was obtained by starting diafiltration after concentrating the broth to 20% PMV. By doing so, a 98% product recovery yield was achieved in the shortest time while keeping the permeate volume at a minimum level.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.22 no.2
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• pp.95-100
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• 2010

In this study we predicted some of the negative effects on the ocean ecosystem and water quality, caused by a coastal reclamation project in semi-closed bay that makes it extremely difficult to be purified by natural process. In order to predict change of water quality triggered by coastal reclamation, the 3D hydrodynamic model and material cycle model are used. And we suggested new ecological park, an artificial beach and eco-friendly revetments on the reclamation area to mitigate the environmental impacts affecting this area using the numerical simulation results and observation data.

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2012.04a
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• pp.488-491
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• 2012

우리나라는 1960년대부터 실시된 조림 정책을 통해 산림이 점차 울창해지고 있어 산림 내 연소물질이 증가되어 산불 피해 강도가 점차 높아지고 있다. 산불방지에 대한 예방차원으로 피해를 저감시키거나 위험을 완화시키는 대표적인 임업적 기술을 적용하는 방법으로 방화림 조성과 방화선 구축을 들 수 있다. 방화림 조성은 산림내 연소물질 관리 또는 수종을 갱신하여 산불확산으로부터 화재강도를 낮추어 산림의 산불위험성을 낮추는 방법이다. 대표적인 기술로는 간벌과 가지치기, 하예작업, 활엽수림 조성 등의 방법이 있다. 방화선 구축작업을 임내 연료물질을 완전히 제거하여 산불이 확산되지 않도록 구축하는 작업이다. 이에 본 연구에서는 일본과 중국의 산불 방화림 조성과 방화선 구축 사례를 조사 분석하여 국내 적용 가능한 기술을 선별하고자 하였다. 그 결과, 산불에 강한 수종을 선발하였고 산불에 강한 숲 조성 방법 및 방화선 구축 방법 등을 도출하였다. 이에 본 연구 결과를 토대로 산림내 주요사찰, 기간시설 및 군사시설 등과 같은 주요시설물이 산불로부터 안전하게 보호되고 피해를 최소화하는데 도움이 될 것으로 사료된다.

• Journal of the Korean Institute of Gas
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• v.21 no.3
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• pp.9-16
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• 2017

Toxic release is one of the most interested area in evaluating consequence to the vicinity of industry facilities handling hazardous materials. Chloric acid production facility is selected and toxic release is evaluated to assess the risk impacted to its off-site. Accident scenarios were listed using process safety information. The scenarios having effect to the off-site were selected and assessed further according to guideline provided by Korea government. Worst case and alternative scenarios including other interested scenarios were evaluated using ALOHA. Each evaluated scenario was assessed further considering countermeasures. The results showed that the facility handling chloric acid is safe enough and needed no further protections at the moment.

• Journal of Life Science
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• v.20 no.6
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• pp.870-876
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• 2010

The purpose of this study was to examine the effect of kinesio taping on muscle strength and changes of muscle fatigue and damage. 10 male subjects participated in 1-RM and isometric cybex muscle strength tests with and without taping application. Muscle strength (bench press, leg press) and extension (knee, shoulder) strength were significantly increased after taping, but there was no significant difference in flexion (knee, shoulder) strength. The concentration of fatigue factors (ammonia, phosphorous), muscle damage index substances (CK, LDH), IGF-I and creatinine were reduced after taping, but there were no significant differences.

• Electrical & Electronic Materials
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• v.9 no.6
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• pp.551-557
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• 1996

To decrease the hysteresis of electric field induced strain, $Y_{2}$ $O_{3}$ dopant of which amount is 0-0.8wt% was added to the (P $b_{0.73}$B $a_{0.27}$)(Z $r_{0}$ 75/ $Ti_{0.25}$) $O_{3}$ ceramics. Electromechanical coupling coefficients of the specimen with 0.1 Wt% $Y_{2}$ $O_{3}$ were $k_{p}$=26.9% and $k_{31}$ =20.4%, which exhibited the maximum value at the constant bias electric field of 10 kV/cm. At the same $Y_{2}$ $O_{3}$ addition amount, electric field piezoelectric constant ( $d_{3l}$) and strain(.DELTA.l/l) showed the maximum values of 139.6*10$^{-12}$ [C/N] and 126*10$^{-6}$ .DELTA. l/l respectively at 10 kV/cm electric field. And the hysteresis of strain showed the minimum value of 17.5%. So, we propose that it is possible to apply PBZT system with $Y_{2}$ $O_{3}$ dopant to the electrostrictive actuator.r.r.

• Journal of the Korean Institute of Gas
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• v.21 no.4
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• pp.6-15
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• 2017

Process safety management(PSM) system was implemented in Korea since 1996. It helps reduce and prevent the occurrence of chemical accidents. There has been no review on the feasibility of the threshold quantities of the existing 21 species and the newly added toxic substances such as hydrogen bromide in the PSM system. The threshold quantities of the target toxic substances(25 species) of PSM were compared with domestic and foreign PSM systems similar to those of Korea. Also, we proposed the toxic harmfulness and hazard equation consisted of inhalation toxicity, NFPA index and others. According to this equation, high risk, medium risk and low risk are classified and reflected in the adjustment of threshold quantities. From the above research, It is expected to help to reduce confusion and burden of the workplaces due to the difference from other PSM system and improve in the threshold quantities.

• Fire Science and Engineering
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• v.14 no.2
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• pp.33-38
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• 2000

Flux, essentially used in soldering process of PCB (Printed Circuit Board) in electronics industry, contains IPA (Isopropyl alcohol) and methanol, which are highly inflammable and explosive. Hazard Chemical Controlling Law classified methanol as toxic material and Environmental Law classified methanol as VOC (Volatile Organic Compound). So there have been pressing needs of developing substitutes for the existing Flux. New solvent which is non-flammable and main component is DCP having same specific character of the existing Flux. It's been combirated with proper composition ratio adding stabilizer. As a result, it relieved working Environment Allowance thickness 200 ppm to 470 ppm, chance of not been soldered 0.083% to 0%, spread 85% to 87%, power saving resistance 1.0$\times$$10^{12}$$\Omega$ to 6.9$\times$$10^{12}$$\Omega$, which means a lot better than the existing Flux. Therefore, Flux confirmed the chance of improving productivity, safety, environment safety and quality. Also, Flux got a satisfied result after product quality test and product reliability test.