• Title/Summary/Keyword: 오류주의

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The Mechanism of Antimutagenic Effect of Cinnamaldehyde on Chemical Mutagenesis (화학적 변이에 대한 Cinnamaldehyde의 항돌연변이)

  • 송근섭;한상배;최동성
    • The Korean Journal of Food And Nutrition
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    • v.10 no.3
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    • pp.407-413
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    • 1997
  • The antimutagenic mechanism of cinnamaldeyde on mutagenesis induced by 4-nitroquinoline-1-oxide(4-NQO) and N-metyl-N'-nitro-N-nitrosoguanidine (MNNG) was investigated in various DNA repair-deficient strains, E. coli B/r and K-12 series. Cinnamaldehyde did not show any effects not only on the $\beta$-galactosidase activities of GW1060 and GW1103(recA441) which synthesizes $\beta$-galactosidase consitutively at 41$^{\circ}C$ but also on that of GW1107[lexA51 (Def)] in which the SOS response always occur. These results suggest that cinnamaldehyde dose not change the function of RecA which positively controls the SOS response as well as not acting as the repressor like LexA. In addition, no inhibitory effect of cinnamaldehyde was observed on the growth of Trp+ revertant and the delay of viable cell growth was also not found by adding cinnamaldehyde. Despite the decrease in the number of revertants, a significant increase in survival of 4-NQO treated cells was observed in E. coli WP2s(uvrA), ZA159($\Delta$uvrB) and TK603(uvrA). But these effects disappeared in excision-proficient strain WP2(uvrA+) and lexA-deficient strains(CM561 and CM611). The enhancement of survival was not found in WP67(uvrA polA) deficient in polymerase I which ligates the gap between complementary DNA. From the above results, we assume that cinnamaldehyde might show antimutagenic effect by enhancing an error-free recombinational repair system.

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Korea's Natural Rate of Unemployment: Estimates and Assessment (한국의 자연실업률 추정)

  • Shin, Sukha
    • KDI Journal of Economic Policy
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    • v.26 no.2
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    • pp.3-62
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    • 2004
  • This paper estimates Korea's natural rate of unemployment using various estimation methods such as pure time-series methods, reduced-form methods, and structural form methods, with discussion about relative advantages and disadvantages of each estimation method. This paper also provides the confidence interval of the estimated natural rate of unemployment by the Monte Carlo integration method. Though multivariate unobserved component model exhibits better performance in many aspects than other estimation methods, awareness should be raised for a potential misspecification problem of a multivariate unobserved component model. Considering that each method has its own advantages and disadvantages, it is recommended to make an inference on the natural rate of unemployment based on common results among various methods. Korea's natural rate of unemployment was estimated to be around 3.8~4.0% on average in the period of 1979:I~1987:IV, and to decline to 2.5~2.9% in the period of 1988:I~1997:IV. During the Asian crisis, it is estimated to peak at near 4.8% and to have been on a downward trend since then.

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A Tablet PC-Based Music-Making Program for Improving Executive Function of Adolescents With Intellectual Disabilities (지적장애 청소년의 집행기능 향상을 위한 태블릿 PC 기반 음악 만들기 활동)

  • Ji, Kyeongmi
    • Journal of Music and Human Behavior
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    • v.12 no.1
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    • pp.1-21
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    • 2015
  • This study examined the effects of a tablet PC-based music-making program on the executive function of adolescents with intellectual disabilities. Four adolescents with intellectual disabilities participated in this program. Each participant received 45-minute individual sessions twice a week for a total of 16 sessions. The music-making program was designed in the sequence of planning; learning table PC operations; exploring musical elements; making rhythm, melody, and lyrics; composing loop sections; and presentation of the completed music. The Stroop test, Children's Color Trails Test, and Digit Span and Letter-Number sequencing tests were measured at pretest, midtest, and posttest in order to examine changes in executive function. The participants showed increased scores on all three tests. The participants' attention span also increased and their attempts to correct errors during tasks occurred more frequently at posttest. This study supports the effects of the technology-based program on the executive function of adolescents with intellectual disabilities and presents its expanded applicability for adolescents who show low cognitive function and limited motivation for cognitive engagement.

Reconstruction of body contour with digital camera image (Digital Camera의 영상을 이용한 신체 단면도 제작)

  • Kwon, KT;Kim, CM;Kang, TY;Park, CS;Song, HK
    • The Journal of Korean Society for Radiation Therapy
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    • v.15 no.1
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    • pp.53-60
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    • 2003
  • I. Purpose It is essential to have the correct body contour information for the calculation of dose distribution. The role of CT images in the radiation oncology field has been increased. But there still exists a method to use cast or lead wire for the body contour drawing. This traditional method has drawbacks such as in accurate and time consuming procedure. This study has been designed to overcome this problem. II. Materials and Methods A digital camera is attached to a pole which stands on the opposite side of the gantry. Positional information was acquired from an image of the phantom which is specially designed for this study and located on the isocenter level of the simulator Laser line on the patients skin or on the phantom surface was digitized and reconstructed as the contour. Verification of usefulness this technique has been done with various shape of phantoms and a patients chest III. Results and Conclusions Contours from the traditional method with the cast or lead wire and the digital image method showed good agreement within experimetal error range. This technique showed more efficiente in time and convenience. For irregular shaped contour, like H&N region, special care are needed. The results suggest that more study is needed. To use of the another photogrammatory techinique with two camera system may be better for the actual clinical application

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Studies of the Efficiency of Wearable Input Interface (웨어러블 입력장치의 인터페이스 효율성에 관한 연구)

  • Lee, Seun-Young;Hong, Ji-Young;Chae, Haeng-Suk;Han, Kwang-Hee
    • Science of Emotion and Sensibility
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    • v.10 no.4
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    • pp.583-601
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    • 2007
  • The desktop interface is not suitable for the environment in which mobile devices are used commonly with moving, because much attention should be paid for it. And the miniaturizing of mobile devices increases the workload for using them, makes the operation speeds lower and makes more errors. So the study of appropriate level of the input interface for this changing environment is needed. In the aspect of mobile devices. input style and the complexity of the menu hierarchy, this study will look for the way to decrease the workload when doing some primary tasks and using mobile devices simultaneously with moving. The input style was classified into gesture input style, button input style, and pointing input style. The accuracy and speed were measured when doing dual tasks, including a menu searching task and a figure memory task, through one input style of three. By Changing the level of menu hierarchy in the menu searching task, the accuracy of task execution was examined. These Experiments were done in standing state and moving state. In both state the pointing input style was the highest in the accuracy of task execution but the slowest in the speed. In contrast, the gesture input style was not high in the accuracy but the fastest in the speed. This fact shows that the gesture input style is suitable for the condition needed for speedy processing rather than accurate execution when moving.

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Text integration processing based on connectives in Aphasics (실어증 환자의 접속사 정보처리에 관한 연구)

  • Kim, Soo-Jeong;Moon, Young-Sun;Kim, Mi-Ra;Kim, Yoo-Jeong;Nam, Ki-Chun
    • Annual Conference on Human and Language Technology
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    • 1999.10e
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    • pp.441-446
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    • 1999
  • 본 연구는 접속사를 통한 텍스트 통합 과정이 논리적 추론 종류에 따라 다른 정보처리 과정 혹은 다른 종류의 단원적 구조(modular structure in language processing)에 의해 처리되는지를 조사하기 위해 실시되었다. 또한, 접속사를 통한 추론 과정이 실어증의 증상 종류에 따라 다른 종류의 언어정보처리 손상이 있는지를 평가하기 위해 실시되었다. 실험에 참가한 환자는 이해성 실어증환자(Wernicke aphasic), 전반성 실어증 환자(Global aphasic), 표현성 실어증 환자(Broca aphasic) 등이었다. en 종류의 과제를 이용하였다. 한 과제는 앞 뒤 문장을 논리적 관계성을 표현하는 접속사를 채워 넣는 과제였고 다른 과제는 접속사가 포함된 텍스트가 옳은지를 판단하는 정오 판단 과제였다. 실험재료 문장에 사용된 접속사는 추가적인 정보를 제공하는 '그리고'와 대등 관계를 나타내는 '그러나' 및 인과 관계를 표현하는 '그래서' 였다. 이 세 종류의 접속사는 각기 다른 논리적 관계성을 나타낸다. 실험 결과는 실어증 환자가 전반적으로 채워 넣기 과제에서 보다는 정오 판단 과제에서 더 많은 실수를 보였으며, 표현성 실어증 환자보다는 이해성 실어증 환자가 더 많은 오류를 보였다. 또한, 세 종류의 접속사 중에 '그리고'가 표함된 텍스트에서 더 많은 실수를 보였다. 이 연구에서 나타난 흥미 있는 결과는 표현성 실어증 환자는 '그러나' 접속사가 포함된 텍스트에서의 수행이 '그래서'가 포함된 경우에서보다 좋은 반면에 전반성 실어증 환자는 '그래서'를 포함하는 텍스트에서의 수행이 '그러나'를 포함하는 텍스트에서의 수행이 더 우수해서 이중해리(double dissociation)가 나타난다는 사실이다. 이 결과는 선후 문장이 어떤 종류의 논리적 관계성을 지니는가에 따라 다른 종류의 정보처리가 진행된다는 것을 암시하는 결과이다.>$\textrm{cm}^2$.。C로 비교적 양호한 초전박막의 전기적 특성을 나타내었다.(Mg+Fe)비를 갖고 전자에 비해 Al이 풍부한 환경에서 생성되었으며, 따라서 활석과 연관되지 않은 녹니석은 생성시 광체와 인접한 화강아질 편마암에 의해 주로영향을 받았을 것으로 생각된다. 녹니석의 이러한 2가지 화학조성상의 경향은 녹니석과 공존하는 운모류나 각섬석류들의 화학분석결과와도 잘 일치한다. 이러한 결과는 이 지역의 활석 광상이 초염기성암 기원의 사문암이 열수변질작용을 받아 생성되었음을 명확하게 지시하며, 따라서 활석 광석내에 존재하는 녹니석은 활석의 근원 광물로서 녹니석편암 및 녹니석 편마암 매의 녹니석이 활석화되고 남은 잔존광물이 아니라, 주변암에 의해 성분상의 영향을 받은 열수와 사문암과의 변질교대작용에 의한 활석화과정 중에 주로 생성된 것으로 추정된다. 이러한 결과는 연구지역의 활석광상이 초염기성암의 사문암화 작용과 활석화 작용의 두 가지 변질작용에 의해 형성되어졌음을 알려준다.농도 증가 없이 폐 조직에 약 50배 정도의 고농도 cisplatin을 투여할 수 있었으며, 또한 분리 폐 관류 시 cisplatin에 의한 직접적 폐 독성은 발견되지 않았다이 낮았으나 통계학적 의의는 없었다[10.0%(4/40) : 8.2%(20/244), p>0.05]. 결론: 비디오흉강경술에서 재발을 낮추기 위해 수술시 폐야 전체를 관찰하여 존재하는 폐기포를 놓치지 않는 것이 중요하며, 폐기포를 확인하지 못한 경우와 이차성 자연기흉에 대해서는 흉막유착술에 더 세심한 주의가 필요하다는 것을 확인하였다. 비디오흉강경수술은 통증이 적고, 입원기간이 짧고, 사회로의 복귀가 빠르며, 고위험군에 적용할 수 있고, 무엇보다도 미용상의 이점이 크다는 면에서 자연기흉에 대해 유용한 치료방법임에는 틀림이 없으나 개흉술에 비해 재발율이 높고 비용이 비싸다는 문제가 제기되고 있는 만큼

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Is Ethics An Enemy of Developing Science and Technology? (윤리는 과학기술발전의 적(敵)인가?)

  • Lee Cho-Sik
    • Journal of Science and Technology Studies
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    • v.1 no.2 s.2
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    • pp.291-309
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    • 2001
  • Let us critique the common notion that ethical examination retards the development of science and technology. First, I shall reformulate such a notion in the following statements: 'To survive the competitive society, we must develop science and technology before others do. It will cost too much time to examine ethically the influence of developing science and technology. Therefore, we cannot but suspend the ethical matters until we have developed science and technology.' I will then show that even if we reconstruct the above argument in a deductively valid form, the second premise is not necessarily true and that we cannot accept the conclusion because the meaning of 'competing for better lives', in the first premise, is diverse. Especially if we are to take into account all the areas of ethics and base them upon the autonomous ethics of democratic societies, it cannot be concluded that ethics is an enemy of developing science and technology. In addition, I will argue that our moral considerations must be based upon autonomous ethics in order to make the development of science and technology contribute to enhancing the desirable science culture. In the midst of making the above argument, it is proposed that the title of the 1aw of bio-ethics be changed, for it has a mistaken implication that acting against ethics results in legal punishments.

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Effect of Lumbar Epidural Nerve Block using the Transforamimnal Approach and the Interlaminar Approach on Magnetic Resonance Imaging Findings (추간공 접근법과 추궁간판 접근법을 사용한 요부 경막외 신경차단술이 자기공명영상 소견에 미치는 영향)

  • Hwang, Byeong-Mun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.8
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    • pp.317-323
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    • 2017
  • This study was conducted to investigate the differences in magnetic resonance imaging (MRI) findings after lumbar epidural nerve block using the transforaminal approach and the interlaminar approach in patients with low back pain. This study was an observational analysis study of abnormal findings of MRI after epidural nerve block. This study included 78 patients who underwent MRI at approximately 24 h after lumbar epidural nerve block at a pain clinic of a university hospital between January 2007 and December 2016. Among patients who received epidural nerve block, 36 used the interlaminar approach and 42 used the transforaminal approach. The incidence of patients with abnormal changes in MRI findings was higher among patients using the interlaminar approach (53%) than those using the transforaminal approach (7%). Abnormal MRI findings included epidural air or fluid, needle tracks, and soft tissue changes, with epidural air being the most frequent abnormal finding (72%). We recommend use of the transforaminal approach to reduce the possibility of misreading or difficulty in interpretation of images of patients who underwent MRI at approximately 24 h after lumbar epidural nerve block. Practitioners should consider the possibility of abnormal findings such as epidural air on MRI in cases of epidural nerve block using the interlaminar approach.

Water-Level Fluctuation due to Groundwater-Surface Water Interaction in Coastal Aquifers (해안대수층에서 지하수-지표수 상호작용에 의한 지하수위 변화)

  • Kim Kue-Young;Lee Cheol-Woo;Kim Yongje;Kim Taehee;Woo Nam-Chil
    • Journal of Soil and Groundwater Environment
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    • v.9 no.4
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    • pp.32-41
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    • 2004
  • Analysis of water-level fluctuation due to goundwater-surface water interaction in coastal aquifers is carried out by numerical modeling. The conceptual model used in this study has a stream boundary and a tidal boundary that forms a right angle and the stream partially penetrates the aquifer. We analyzed the effect of each boundary and the simultaneous effect of the two boundary conditions. The area of influence caused by the stream boundary increased during the simulation, while the influence zone of the coastal boundary was relatively constant. The groundwater level near the zone where two boundaries meet may rise by the action of combined effect of the two boundaries or may not change by cancelling the effect of each boundary. Thereafter, care must be taken when hydraulic parameters are estimated using sinusoidal oscillations of hydraulic head in coastal aquifers. Sensitivity analysis is employed to develop insight into the controls on groundwater level fluctuations. In this study our analyses focused on the effect of conductance and the stream width to the aquifer nearby.

How Science-Engineering Graduates Become so Powerful Elites in China? (중국의 이공계 강세 현상에 대한 고찰)

  • ;Bak Hee-Je
    • Journal of Science and Technology Studies
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    • v.4 no.2 s.8
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    • pp.1-32
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    • 2004
  • Korean scientific community has recently argued that, in order to attract talented young people to the science and engineering fields, more ranking positions in the governmental office should be filled in by science and engineering majors. In this context, a special attention has been paid to the Chinese case where science and engineering majors have taken the highest places in Chinese political hierarchy. This paper examines historical and social background of the salience of science and engineering fields in modem China. A closer examination shows that the salience of science and engineering fields was resulted by the distinct historical experiences of China-the socialist reform of higher education system and Cultural Revolution. The former shaped the social conviction that humanities and social sciences are less useful than science and engineering fields. The latter even spread the idea that majoring in humanities or social sciences run the risk of political oppressions. Thus, the salience of science and engineering in China is a social phenomenon reflecting an academic hierarchy forced by the radical politics of modem China. Also, the higher proportion of science and engineering majors in the raking governmental officers has been resulted by a unique Chinese political system, in particular the personnel management system of the Chinese Communist Party that emphasizes practical experiences after college graduation. The comparison of the social position of science and engineering majors in China and Korea without taking account of such historical and social background may therefore mislead our understanding of the cause of and counterplan to the decreasing popularity of science and engineering fields in Korean universities.

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