• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.5 no.2
• /
• pp.174-180
• /
• 2002

Purpose: Ursodeoxycholic acid (UDCA) is known to decrease hepatic injury by promoting the biliary secretion of retained toxic endogenous bile acids in hepatobiliary diseases complicated by total parenteral nutrition (TPN). However, most studies have focused on treatment for complications after TPN. We investigated the preventive role of early administration of UDCA in TPN-induced hepatobiliary complications by a randomized, double-blind, placebo-controlled trial. Methods: Between May 2000 and May 2002, thirteen patients, who were given TPN more than 10 days in the hospital, were assigned randomly to two groups. One was the case group (7 patients) who were given UDCA simultaneously with TPN regimen, and the other, the control group (6 patients) who were given placebo. Their age ranged from 1 day to 13 years. They were affected with diseases impossible for enteral nutrition, such as prematurity, cerebral palsy, chronic diarrhea, anorexia nervosa, pancreatitis, and cyclic vomiting. The duration of TPN ranged from 10 to 70 days. Hematologic parameters including liver function test were measured at regular intervals, and the duration, composition, administration rate, total calorie of TPN were recorded. The serum levels of total bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase were compared between groups after cessation of the study. Results: The autoregressive coefficient of the control group was 0.4419 (p=0.0651) in bilirubin, -0.0431 (p=0.7923) in AST, 0.2398 (p=0.2416) in ALT, and 0.2459 (p=0.1922) in alkaline phosphatase by mixed procedure model when the parameters were referred to the case group. Conclusion: The serum level of total bilirubin did not increase in comparison with that of the control group, but statistically insignificant, when both TPN and UDCA were administered simultaneously from the beginning.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2007.05a
• /
• pp.1038-1042
• /
• 2007

수변완충지대는 수역과 육역의 경계에 위치하면서 하도를 따라 선형으로 길게 연속적으로 이어지는 공간으로서 토양, 동식물 등 생태시스템을 이루는 자연공간이다. 수변완충지대의 기능은 일반적으로 수질정화, 생태통로 및 서식처, 강턱의 안정, 토양침식 방지, 경관 개선 등이며 하천의 일부로서 사회적 경제적으로 높은 가치를 지니고 있다. 특히 최근에는 비점오염 저감과 하천 생태서식처 조성분야에서의 적용이 활발히 검토되고 있다. 선진국에서는 1980년대 이후부터 수변완충지대의 중요성을 인식하고 환경 생태 치수 측면에서 효율적 조성 및 복원 방법에 관한 연구와 적용이 본격적으로 시작되었고 가이드라인이 제시되었다. 이 분야에서 기술적 정책적으로 가장 앞선 나라로 평가되고 있는 미국의 경우 정부에서는 농무부(USDA)를 비롯하여 환경처(EPA), 내무부(USDI), 공병단(US ARMY)의 관련 산하기관, 각 주정부의 담당부서에서 수변완충지대의 보전과 조성에 관련된 여러 가지 정책과 기준을 제시하고 있다. 이들 가이드라인에서는 수변완충지대가 필요로 하는 기능별 최소 폭, 식생 종별 구성, 식생배열 등을 제시하며 그 기준은 조성 목적이나 기능, 대상 지역별로 차이를 보인다. 기능별 최소 폭은 수질정화를 목적으로 하는 경우 $4m{\sim}61m$이상, 생태서식처 조성을 목적으로 하는 경우는 $30m{\sim}1,000m$ 이상을 권장하고 있다. 식생 종은 수변완충지대 폭을 상 중 하단부로 나누어 초본, 관목, 교목류로 식재하고 강우유출수의 유입부에서 초본을 통한 부유고형물 등을 여과하고, 목본류의 뿌리와 토양을 통해 질소, 인 등 영양물질을 저감하는 구조를 제시하고 있다. 미국의 경우는 이러한 가이드라인을 실제로 현장에 적용하고 있으며 조성효과가 정성적으로 검증되었고 정량적인 관계 도출을 위한 연구가 지속적으로 진행되고 있다. 국내의 경우 수질개선 및 생태서식처 조성, 하천환경을 개선하기 위한 관련 정책이 꾸준히 제시되고 있다. 한 예로 정부에서는 수변구역을 지정 고시하여 상수원으로 유입되는 비점오염물질을 저감하고 생태서식처를 조성함으로써 양질의 상수원과 건전한 생태계를 확보하기 위한 제도를 시행 중이다. 수변 구역의 범위는 한강수변구역의 경우 약 $500{\sim}1,000m$로 설정되어 있으나 아직까지는 관리적 성격이 강하며, 향후에는 구체적인 조성방안이 요구된다. 본 연구에서는 한강 수변구역 내에 미국의 가이드라인에서 제시하는 수변완충지대의 물리적 조건과 국내 지역 토착식생을 적용하여 시험완충지대를 조성하였고, 실험조건 하에서 그 효과를 정량적으로 분석 검증한 결과와 외국사례를 분석하여 국내여건에 맞는 수변완충지대 조성 가이드라인(안)을 제시하였다.

• Journal of Nutrition and Health
• /
• v.26 no.6
• /
• pp.793-803
• /
• 1993

This study was designed to measure viscosity, osmolality and in vitro flow rates via nasogastric tubes for 6 types of commercially available and 9 hospital-blenderized enteral solutions and to examine the effect of viscosity and osmolaility of enteral formula on the flow rates in gravity drip administration. Each solution was infused through 18, 16, 14, 12 French sizes of silicone rubber tube. Flow rates were measured six times at $25^{\circ}C$ using formula bags and drip sets hung at a uniform height on a intravenous drip stand with tube uniformly positioned in collecting container. Viscosity ranged widely from 16.0 to 195.5 cps with mean, 64.61$\pm$64.42 for hospital-blenderized formula while mean viscosity of commercial formula was 7.60$\pm$4.84 cps. Mean osmolality of commercial formula and hospital-blenderized formula were 370$\pm$100.80, 540.33$\pm$89.37 mOsm/kg respectively. There was negative relationship between viscosity of formula and flow rates through tubes but no significant relationship between flow rates and osmolalty. Some of hospital-blenderized formula was too viscous to be infused througth tube with gravity drip administration and the recipe of formula requires to be modiifed. On the other hand, commercial formula with the low viscosity flows too rapidly with large bore size tubes. Smaller size of tube must be selected for hyperosmolar solution to decrease possible side effects associated with tube feeding. Two kinds of regression equations for flow rates obtained according to viscosity and tube sizes were also presented for the purpose of practical uses. In conclusion, this study emphasizes that viscosity of fomula, osmolality, patient's tolerance and comfort, caloric density should be considered in the selection of tubes for gravify drip administration.

• Journal of Nutrition and Health
• /
• v.25 no.7
• /
• pp.668-683
• /
• 1992

To evaluate the current practices of the tube feeding and the status of tube feeding patient 76 adult in-patients at 6 hospitals located in Seoul and Chung-buk province were examined through reviewing patient charts observing patients and interviewing patients nurses dietitians patients' family or care-givers. The results were as follows : 1) An average age of the patients was 54.5 years with 41% over 60 years old. Patients with decreased mental status dysphagia esophageal obstruction and respiratory problem were fed by tubes. 2) The range of duration of tube feeding is between 4 days and 6 years. Most patients were received formula through nasogastric tube(89.5%) while 7.9% of gastrostomy and 2.6% of jejunostomy. Administration method for formula were bolus feeding regardless of the route of formula delivery. 3) Mean total calories received for men were 1590 kcal and 1450 kcal for female. Mean volume per meal was 282m, l and mean frequency of feeding was 5.68 while mean feeding interval 3$\frac{1}{4}$ hours and mean rate of infusion 68.4ml/min. All patients received hospital-blenderi-zed formula as the major source of nutrition. Home-blenderized formula and commercial formula as a supplement were used 35%, 13.2% respectively. 4) Thirty-eight percent of patients was hypoalbuminemia and 61% was at the moderate level of deficiency in hemoglobin. 5) Complications associated with tube feeding were diarrhea (22.4%) constipation(21.1%) vomiting(11.8%) and so on. 6) Serum albumin levels of patients who have complications associated with tube feeding were significantly lower than those of patients without complications In planning a tube feeding regimen the type of a formula must be integrated with both a delivery system and a protocol for administering the tube feeding. the multidisciplinary effort required to deliver enteral therapy is essential to improve current practices used at hospitals.

• Journal of the Korean Dietetic Association
• /
• v.21 no.1
• /
• pp.11-24
• /
• 2015

This study investigated the general status of tube feeding for intensive care unit (ICU) inpatients and evaluated the consequent nutritional status of patients. This study was approved by the Institutional Review Board (IRB) of a general hospital located in Daegu metropolitan city. The subjects of this study were 80 adult patients who had been admitted to the ICU of a hospital, received fed tube feeding, and then been discharged. The differences in nutrition screening indicators, including percentage ideal body weight (PIBW), serum albumin, hemoglobin, total lymphocyte count, and total cholesterol, before and after tube feeding according to body mass index (BMI) or nutrient feeding levels were investigated. The ratios of actually provided amounts to calorie and protein requirements of patients were $72.8{\pm}15.8%$ and $72.6{\pm}19.8%$, respectively. The change in PIBW before and after tube feeding was significantly different among the BMI groups (P<0.01). The change in hemoglobin concentration before and after tube feeding was also significantly different among the BMI groups (P<0.01). When subjects were divided into three groups (<60%, 60~79%, ${\geq}80%$) according to the ratio of actually provided calories to required calories, there was no significant difference in nutrition screening indicators before and after tube feeding. When the subjects were divided into three groups (<60%, 60~79%, ${\geq}80%$) according to the ratio of actually provided protein to required protein, serum albumin concentration showed a significant difference among the groups before and after tube feeding (P<0.05). Therefore, an intensive nutrition intervention program would be needed for the nutritional improvement of ICU inpatients receiving tube feeding.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2018.05a
• /
• pp.357-357
• /
• 2018

기후변화의 영향으로 기온과 강수량의 증가가 나타나고 있으며, 이러한 변화는 수문 순환 및 강우-유출의 변화로 인해 하천의 수질에도 영향을 미치게 된다. 수질 오염원 중 배출원의 형태가 명확하지 않은 비점오염원은 강우의 유출과 함께 발생하는 특징을 띤다. 비점오염원은 지표면에 존재하던 오염 물질이 지표면에서 유출이 발생함에 따라 하천으로 유입되는 오염물이다. 이에 따라 강우량에 비례하는 특성을 띠며 점 오염원과 달리 변동 폭이 크다. 대표적인 비점오염물로 알려진 질소, 인과 같은 영양물질은 하천으로 유입 시 부영양화를 야기하는 물질로 우리나라와 같이 계절별 강수량의 차이가 큰 환경에서 비점오염물의 지속적인 관리는 필수적이라 할 수 있다. 비점오염원은 오염원을 특정할 수 없기 때문에 하천으로의 유입을 최소화하는 최적관리기법(Best Management Practices)을 통해 관리한다. 국내외에서 가장 널리 이용되는 비점오염원 최적관리기법은 식생형 시설로, 나지에 식물체를 파종함으로써 토양의 유실을 방지하여 비점오염물의 하천 유입을 저감시키고, 자연경관으로써 기능한다. 미래 수자원의 효과적인 이용을 위해서는 기후변화에 따른 수문 변화, 그로 인한 수질 변화 특성을 파악하는 것은 매우 중요하다. 이에 본 연구에서는 기후변화 시나리오를 통해 기온, 강수, 습도와 같은 기후 조건의 변화를 고려하여 예측되는 비점오염물의 유출 저감 대책의 영향을 분석하고자 한다. 이 때, 기후변화 시나리오는 그 자체로 불확실성을 포함하는 자료이기 때문에 특정 시나리오를 분석하기 보다는 기후변화 진행 정도에 따른 비점오염물 유출을 산정하고 저감 대책의 영향을 분석한다. 연구를 수행하기 위해 장기간의 강우-유출 특성의 모의가 가능하고 저감 대책을 제공하는 SWAT 모형을 이용한다. SWAT 모형에서는 여러 최적관리기법을 제공하는데, 가장 널리 이용되는 것이 식생형 시설인 것에 기초하여 적용할 저감 대책으로 계단식 산비탈(Terracing)을 선정하였다. 저감 대책의 적용으로 비점오염물질이 적게는 약 30%에서 많게는 60%까지 변화하며 매우 효율적으로 저감되는 것이 확인되었다. 저감 시설의 적용을 통해 총 량 뿐만 아니라 시간에 따른 비점오염물 유출의 변동성 또한 감소시킬 수 있음이 확인되었다.

• Korean Journal of Plant Resources
• /
• v.27 no.1
• /
• pp.80-88
• /
• 2014

This study was carried out to understand the effect of sowing date on growth characteristics, flower duration of a total of 6 domestic rapeseed cultivars, "Sunmang", "Tammiyuchae", "Tamlayuchae", "Naehanyuchae", "Yongsanyuchae" and "Hallayuchae" with different sowing dates (25 Sept., 5 Oct., 15 Oct., 25 Oct., 5 Nov.) in Muan, Jeollanamdo, Republic of Korea. The results obtained were summarized as the follows: The number of seedling stand after overwintering was decreased in all 6 cultivars. It changed little until 5 Oct., and then showed continuously largely decrease as the sowing date being delayed. As the sowing date was being delayed, plant height was decreased while Silique length and thousand seed weight were increased. Seed yield in all 6 cultivars decreased almost linearly with late sowing date. In correlation analysis between the delaying sowing date and growth characteristics, it was inversely correlated with plant height ($r=-0.769^{**}$), No. of branches/plant ($r=-0.760^{**}$), No. of siliqua/panicle ($r=-0.631^{**}$) and seed yield ($r=-0.946^{**}$), while showed a positive correlation with silique length (r=0.635), seed diameter ($r=0.629^{**}$) and thousand grain weight ($r=0.422^*$). No. of seeds/silique and seed set percentage were not significantly correlated with the delaying sowing date. The flower duration was long in order of Sunmang, Tammiyuchae, Yongsanyuchae, Naehanyuchae, Hallayuchae and Tamlayuchae. Varietal variation of flowering date was larger with early sowing date than with delaying sowing date. The range of flower duration across all cultivars was from 1 day of Tamlayuchae to 14 days of Sunmang according to the sowing date, and the end flowering date was able to be extended from 2 to 9 days, compared to normal date of end flowering.

• Ecology and Resilient Infrastructure
• /
• v.3 no.3
• /
• pp.207-211
• /
• 2016

This study focuses on the categorization of the phenomenon of vegetative recruitment on riparian channels, so called, the phenomenon from "white river" to "green river", and proposes for the corresponding research direction. According to the literature review and research outputs obtained from the authors' previous research performed in Korea within a limited scope, the necessary and sufficient conditions for the recruitment and retrogression of riparian vegetation may be the mechanical disturbance (riverbed tractive stress), soil moisture (groundwater level, topography, composition of riverbed material, precipitation etc.), period of submergence, extreme weather, and nutrient inflow. In this study, two categories, one for the reduction in spring flood due to the change in spring precipitation pattern in unregulated rivers and the other for the increase in nutrient inflow into streams, both of which were partially proved, have been added in the categorization of the vegetative recruitment and retrogression on the riparian channels. In order to scientifically investigate further the phenomenon of the riparian vegetative recruitment and retrogression and develop the working riparian vegetative models, it is necessary to conduct a systematic nationwide survey on the "white to green" rivers, establishment of the categorization of the vegetation recruitment and retrogression based on the proof of those hypotheses and detailed categorization, development of the working mathematical models for the dynamic riparian vegetative recruitment and retrogression, and adaptive management for the river changes.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.44 no.8
• /
• pp.1200-1205
• /
• 2015

Medical foods are enteral nutrition for patients, but they cause maladaptation symptoms like diarrhea. Although the cause of diarrhea remains unknown, some studies have indicated that the cause of diarrhea is fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP). This is a consideration for medical foods since they are easily fermented by intestinal bacterial. In this study, we estimated the FODMAP contents of commercial medical foods and carbohydrate ingredients. We measured the concentrations of FODMAP in 13 types of different medical foods and five types of carbohydrate ingredients by using high performance liquid chromatography with an evaporative light scattering detector (HPLC-ELSD). The limits of detection of FODMAP were fructose, 0.002; lactose, 0.010; raffinose, 0.003; stachyose, 0.032; 1-kestose, 0.005; nystose, 0.012; and 1-fructofuranosylnystose, 0.003 mg/kg. Limits of quantitation of FODMAP were fructose, 0.008; lactose, 0.033; raffinose, 0.009; stachyose, 0.107; 1-kestose, 0.015; nystose, 0.042; and 1-fructofuranosylnystose, 0.011 mg/kg, respectively. Concentration of FODMAP ranged from 0.428~2.968 g/200 mL. Concentrations of carbohydrate ingredients in FODMAP were chicory fiber, 278.423; soy fiber, 27.467; indigestible maltodextrin, 52.384; maltodextrin (DE10~15), 32.973; and maltodextrin (DE15~20), 50.043 g/kg. Contents of carbohydrates were 19.0~41.0 g/200 mL in commercial medical foods. We expected a correlation between contents of carbohydrates and FODMAP, as carbohydrates included FODMAP. However, we detected a low correlation (r=0.55). Since most commercial medical foods have a similar carbohydrate ingredients and nutritional values, the difference between products was determined by FODMAP contents of carbohydrate ingredients. In this study, we analyzed FODMAP contents of commercial medical foods and carbohydrate ingredients. These results are expected to be utilized as basic data for product development and minimizing maladaptation of medical foods.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2006.05a
• /
• pp.1073-1077
• /
• 2006

급속한 산업화로 인한 오염물질의 증가와 생물서식처의 감소는 수자원과 생태계를 위협하고 있다. 국내의 경우 수자원의 질을 개선하기 위해 '90년대 초부터 하수처리시설 등의 저감시설을 대폭 확충하였으나 현재까지 팔당호 등 주요상수원이 목표수질에 못 미치고 있으며 그 원인은 유입오염물질의 $22{\sim}37%$를 차지하는 비점오염원으로 지목되고 있다. 또한 생태.경관적 가치가 높은 수변지역은 각종 개발로 생물서식처가 급속도로 감소하여 종 다양성 보전 측면에서 대책마련이 시급한 실정이다. 이와 유사한 상황에 직면한 선진외국에서는 '하천회랑(river corridor)' 또는 '토양 및 생태시스템을 포함하는 수역과 육역의 점이(漸移)지대'를 의미하는 이른바 '수변완충지대(Riparian Buffer Zones)'의 오염정화 및 생태조성 효과 등의 연구를 통해 효율적 조성방안을 제시하고 있으며 다양한 형태로 현장에 적용하고 있다. RBZs의 일반적인 기능으로는, 유사나 오염물질의 여과 및 차단(필터링 효과), 영양염류의 저감, 하천변 식생을 통한 수자원의 정화 및 강턱의 안정화, 홍수로 인한 하천침식의 방지, 수변 생물 서식처 제공, 수변 그늘 제공에 의한 수온상승 방지, 심미 교육 위락 공간 제공 등이다. 본 연구에서는 외국의 RBZs(Riparian Buffer Zones)가이드라인을 참고하여 국내실정에 맞는 파일럿 규모의 시험완충지를 설계 및 조성하였다. 시험완충지는 남한강 연안에 초본류, 갈대류, 관목류, 자연식생, 혼합식생 등 5가지 'dry biotope'형태로 설치하여 1년간 계절별로 운영하였다. 또한 실험의 정량화와 다양한 조건변화를 위해 차수막, 위어, 유량.농도 조절장치, 라이시미터 등 보조시설을 설치하였고, 정기적인 모니터링을 실시하였다. 조사결과 외국사례를 살펴보면 RBZs의 적정 폭은 수질정화기능의 경우 $15{\sim}30m$, 생태서식처 기능은 최소 90m이상으로 제시되며, 시험완충지의 수질정화효과는 SS, T-N, T-P, TOC의 평균저감율이 각각 50%이상으로 나타났다. 식생모니터링 결과, 환삼덩굴 등 우점종의 잠식속도는 약 15일이며 갈대와 갯버들의 경우 우기시 인공목책호안과 동일한 침식방지 효과를 보이는 것으로 관찰되어 식생의 주기적인 모니터링과 지역 특성에 적합한 우점종 선정이 매우 중요한 것으로 판단된다.