• Title/Summary/Keyword: 연쇄관계

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An estimation method for stochastic reaction model (확률적 방법에 기반한 화학 반응 모형의 모수 추정 방법)

  • Choi, Boseung
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.4
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    • pp.813-826
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    • 2015
  • This research deals with an estimation method for kinetic reaction model. The kinetic reaction model is a model to explain spread or changing process based on interaction between species on the Biochemical area. This model can be applied to a model for disease spreading as well as a model for system Biology. In the search, we assumed that the spread of species is stochastic and we construct the reaction model based on stochastic movement. We utilized Gillespie algorithm in order to construct likelihood function. We introduced a Bayesian estimation method using Markov chain Monte Carlo methods that produces more stable results. We applied the Bayesian estimation method to the Lotka-Volterra model and gene transcription model and had more stable estimation results.

조류를 이용한 유기성 폐수 처리 시스템과 물벼룩 성장 조건

  • Jo, Jae-Hun;Kim, Jun-Hwi;Lee, Jeong-Seop;Yun, Seong-Myeong;Kim, Si-Uk
    • 한국생물공학회:학술대회논문집
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    • 2001.11a
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    • pp.568-571
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    • 2001
  • Food wastewater eluted from the three-stage methane fermentation system developed in this lab showed high concentrations of TCOD, BOD, T-N and T-P. Because the effluent of biological filter chamber (BFC) still had high concentration of nitrogen and organic material, the effluent was treated with algal periphyton system using algae. The removal rates of COD, T-N and T-P wer 96, 98 and 91%, respectively, in this system. The grown algae could digested byy waterfleas using the ecological food chain system. Food wastewater is better than algal culture medium for growth of waterflea, Moima Macrocopa. During 12days, the individual of waterflea increased to 180 in the food wastewater containing a T-N concentration of 150 mg/ ${\ell}$.

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A Linkage Study of Chromosome 5 D5S39(p105-153Ra), D5S76(p105-599Ha), and $D_2$, $D_3$ Receptor Gene($DRD_2$, $DRD_3$) in Schizophrenics in Korean Pedigree (한국인 정신분열병 가계의 염색체 5번 D5S39(p105-153Ra), D5S76(p105-599Ha) 및 도파민 $D_2$, $D_3$ 수용체 유전자좌간의 연관관계 연구)

  • Oh, Kang-Seob;Kim, Young-Tae;Lee, Min-Soo
    • Korean Journal of Biological Psychiatry
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    • v.1 no.1
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    • pp.67-78
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    • 1994
  • The author examined the relationship of two markers, D5S39(p105-153Ra), D5S76(p105-599Ha) of chromosome 5 and $D_2$, $D_3$ receptor genes in a Korean schizophrenic pedigree using polymerase chain reaction(PCR). The results were as follows : 1) On D5S39 locus, 5 different alleles(224/226 bp : 4 cases, 218/226 bp : 3 cases, 222/226 bp : 3 cases, 218/230 bp : 1 case, 222/224 bp : 1 case) were produced. 2) On D5S76 locus, 5 different alleles(102/112 bp : 4 cases, 94/112 bp : 3 cases, 108/112 bp 3 cases, 94/94 bp : 1 case, 102/108 bp 1 case) were produced. 3) On $D_2$ receptor gene, 3 different alleles($A_1A_2$ : 8 cases, $A_1A_1$ : 2 cases, $A_2A_2$ : cases) were produced. 4) On $D_3$ receptor gene, 2 different alleles(1/2 : 7 cases, 1/1 : 5 cases) were produced. The author had not find any specific alleles on all four loci in all pedigree nor any specific alleles in the schizophrenic patients. Though the author has not found absolute relationship between the four loci and the onset of schizophrenia, there still remains the possibilities if the more detailed and elaborated pedigree studies are done.

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Relationship Between Mitochondrial DNA Copy Number, Metabolic Abnormalities and Hepatic Steatosis (지방간 및 대사 인자들과 말초혈액 백혈구의 사립체 DNA copy 수와의 연관성)

  • Kwon, Kil-Young;Jun, Dae-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.6
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    • pp.2093-2098
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    • 2010
  • Insulin resistance plays a central role in fatty liver, a part of the metabolic syndrome. This study examined the relationship between fatty liver, metabolic abnormalities and mitochondrial DNA [mtDNA] copy number in peripheral blood that is correlated with diabetes or metabolic markers. Fatty liver was assessed by questionnaire on alcohol consumption and abdominal ultrasonography. MtDNA copy number in peripheral leukocytes was measured by a real-time quantitative polymerase chain reaction [PCR]. Among 445 subjects, 148 subjects had hepatic steatosis and 297 were controls. mtDNA copy number was significantly lower in fatty liver group in comparison with that of normal finding group. This result is similar in both groups, alcoholic or non-alcoholic fatty liver group. MtDNA copy number was inversely correlated with alanine aminotransferase [ALT], aspartate aminotransferase [AST], gamma-glutamyltransferase [$\gamma$-GTP], body mass index [BMI], waist circumference, diastolic blood pressure, and free fatty acid. MtDNA copy number in peripheral leukocytes was associated with fatty liver and insulin resistance related factors.

Fundamental Study for RAPD-PR Analysis in the Silkworm, Bombyx mori (누에 RAPD-PCR 분석을 위한 기초연구)

  • 황재삼;이진성
    • Journal of Sericultural and Entomological Science
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    • v.38 no.1
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    • pp.7-12
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    • 1996
  • Reproducible the random amplified polymorphic DNAs(RAPDs) patterns were obtained in the two silkworm strains(J111, Galwon) by adjusting concentration optimized of Taq DNA polymerase(one unit), dNTP(200$\mu$M), MgCl2(1.5mM) and template DNA(30ng). In addition, anealing temperature ranging 35$^{\circ}C$ to 42$^{\circ}C$ by the adjusted condition was investigated and fixed at 35$^{\circ}C$ in this study. Variation among individuals and between male and female of Jam 113 strain was not authorized. DNA polymorhpisms among silkworms were authorized by five RAPD markers using OPM04 random primer. Using the primer showing polymorhpims between parents(J111, Galwon) in thirty three individuals, RAPD-PCR for F2 analysis was performed and segregated 3 : 1 in the F2 population. Consequently, RAPDs detected in the parents were obtained as genetic markers, which can be used for construction of genetic map for this industrially particular insect, silkworm Bombyx mori

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Result of Surgical Treatment for Infective Endocarditis (심내막염 환자의 수술적 치료성적)

  • Choe, Sun-Ho;Yang, Hyeon-Ung;Lee, Sam-Yun
    • Journal of Chest Surgery
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    • v.29 no.2
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    • pp.157-163
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    • 1996
  • Between January 1986 and June 1994, 23 patients underwent surgical intervention for infective endocarditis at Wonkwang University Hospital. There were 13 male and 5 female, ran ing in age from 13 to 67(mean 43.7 $\pm$ 5.8) years. 21 had native valve endocarditis and 2 had prosthetic valve endocardits. The most common causative organism was streptococci in 9 patients, and the others were staphylococci in 7 patients and unknown in 7 patients. The infection was in the mitral valve in 10 patients, the aortic valve in 6 patients, the aortic and mitral In 5 patients, 2 in tricuspid. Surgical indications for surgery were intractable congestive heart failure, giant growing vegetation and severe valvular insufficiency. There were 3 perioperative death (13%) and no late death. The main causes of death were cerebral embolism in 2 due to recurrent endocarditis and low cardiac output in 1. By NYHA functional classification, all patients were in class III or IV preoperatively, and all patients were improved postoperatively with HYHA functional classification in class I or II. In conclussion, early operative intervention is life-salving in patients with persistent or progres ive congestive heart failure, irrespective of the activity of the infectious process or the duration of antibiotic therapy.

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The Risk Assessment and Prediction for the Mixed Deterioration in Cable Bridges Using a Stochastic Bayesian Modeling (확률론적 베이지언 모델링에 의한 케이블 교량의 복합열화 리스크 평가 및 예측시스템)

  • Cho, Tae Jun;Lee, Jeong Bae;Kim, Seong Soo
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.16 no.5
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    • pp.29-39
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    • 2012
  • The main objective is to predict the future degradation and maintenance budget for a suspension bridge system. Bayesian inference is applied to find the posterior probability density function of the source parameters (damage indices and serviceability), given ten years of maintenance data. The posterior distribution of the parameters is sampled using a Markov chain Monte Carlo method. The simulated risk prediction for decreased serviceability conditions are posterior distributions based on prior distribution and likelihood of data updated from annual maintenance tasks. Compared with conventional linear prediction model, the proposed quadratic model provides highly improved convergence and closeness to measured data in terms of serviceability, risky factors, and maintenance budget for bridge components, which allows forecasting a future performance and financial management of complex infrastructures based on the proposed quadratic stochastic regression model.

BACTERIOLOGICAL STUDIES ON MARKET SEA FOODS 2. Sanitary Indicative Bacteria in Slices of Raw Fish (시판 수산식품에 대한 세균학적 연구 2. 생선회의 위생지표 세균에 관하여)

  • CHANG Dong-Suck;CHOE Wi-Kyung
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.6 no.3_4
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    • pp.92-96
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    • 1973
  • This examination was carried out to evaluate the sanitary quality of slices of raw fish being served in the restaurants. Twenty five kinds of slices of raw fish collected from various restaurants in Busan Korea were examined during the period from March to May in 1971. As the evaluation factors of sanitary quality, the contents of sanitary indicative bacteria such as coliform group, fecal coliform, feral streptococci and enterococci and plate counts were determined. The results obtained are as in below: 1. The numbers of fecal streptococci and enterococci MPN were much greater than those of coliform group and fecal coliform. 2. The median value of coliform group MPN was 3,300 per 100 grams of the sample examined and those of enterococci was 5,400. The median value of plate counts was $1.8\times10^5$ per gram. 3. Fifty-two percent of the samples examined were exceeded fecal coliform MPN 930 per 100 grams. 4. As a sanitary indicative bacteria fecal coliform MPN was more reasonable than enterococci 5. The grade of restaurants was not correlated with the bacterial quality of the foods served. 6. No correlation between the numbers of sanitary indicative bacteria ana plate counts was observed.

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The Service Industry Growth and the Productivity: Evidence from 13 OECD Countries (서비스 산업의 성장과 생산성 - OECD 13국을 대상으로 -)

  • Kim, Soo-Eun;Hwang, Yun-Seop
    • International Commerce and Information Review
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    • v.14 no.2
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    • pp.271-293
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    • 2012
  • As service industry became more important, many of studies have been done on the role of service. Such studies has been researched focusing on the relationship between the service intensity in the economy and a country's productivity. Baumal(1967) suggested that service growth in economy would bring about decrease in productivity. However, the economy of developed countries encounter with the productivity growth as their economy grows, which phenomenon called Baumol's paradox. Oulton (1999, 2001) find out the reason of Baumol's paradox in a forward and backward chain effects. So, this paper is aimed at verifying the theory of Oulton (1999, 2001) for 13 OECD countries using panel data analysis. We find out that the intermediate knowledge-intensive service inputs cause a multifactor productivity growth.

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Analysis of the Degraded Performance and Restoration Plan of Lfieline Systems Considering Interdependency in the Post-disaster (라이프라인 시스템 상호의존성을 고려한 기능 저하 평가 및 복구계획 분석)

  • Lee, Seulbi;Park, Moonseo;Lee, Hyun-Soo;Hwang, Sungjoo
    • Korean Journal of Construction Engineering and Management
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    • v.15 no.4
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    • pp.139-149
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    • 2014
  • Lifeline service disruptions can have significant impacts on local community in the aftermath natural disaster. Although effective restoration strategies with accurate damage assessment are required, the internal complexity of lifeline networks and their interdependency makes the understanding restoration process of lifeline systems a difficult issue. Additionally, the limitations of previous research relating the influence assessment of lifeline to community disaster resilience, highlight the need for understanding of lifeline networks. Therefore, this paper presents an agent-based model to discover emergent behavior and evaluate the interdependency and resiliency in lifeline networks. This research will provide basic guideline of resource allocation in order to mitigate cascading failures of the post disaster restoration processes.