• Title/Summary/Keyword: 연속추적

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Measuring in vivo Rate of Bone Collagen Synthesis in Growing Rats (성장기 흰쥐의 골조직 Collagen 생성속도 측정)

  • 김유경
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.8
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    • pp.1390-1393
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    • 2003
  • Measuring in vivo rate of bone collagen synthesis has so far been technically difficult and often subject to quite large errors. In the present study, bone collagen synthesis rate was measured using a precursor-product method, based on the exchange of $^2$$H_2O$ into amino acids. Mass isotopomer abundance in hydroxyproline from bone collagen was analyzed by gas chromatography/mass spectrometry. The $^2$$H_2O$ labeling protocol consisted of an initial intraperitoneal injection of 99.9% $^2$$H_2O$, to achieve approximately 2.5% body water enrichment followed by administration of 4% $^2$$H_2O$ in drinking water for 9 weeks. Body $^2$$H_2O$ enrichments were stable at 2.7 ∼ 3.0% over labeling Period. In growing rats, the fractional synthesis rate ( $k_{s}$) of bone collagen was 0.066 $\pm$ 0.049 w $k^{-1}$ . The unique features of stable $^2$$H_2O$ pools and label incorporation allowed the precursor-product approach to be used for measuring bone collagen synthesis rate..

결체조직질병(結締組織疾病)에 병발(倂發)된 간질성폐병변(間質性肺病變)에 대(對)한 활혈화어법(活血化瘀法)의 치료효과(治燎效果) 연구(硏究)

  • 장항홍
    • Journal of Haehwa Medicine
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    • v.5 no.2
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    • pp.497-497
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    • 1997
  • 간질성폐질변(間質性肺疾變)은 결체조직질병(結締組織疾病)의 상견(常見)되는 병발증(倂發證)이지만, 지금까지는 이상적(理想的)인 치료법(治療法)이 없었다. 본(本) 연구(硏究)는 본병(本病)의 병리기전(病理機轉)이 중의(中醫)에서의 "어혈(瘀血)"증(證) 상호(相互) 유사(類似)한 것으로부터 시작(始作)하여, 중의(中醫)의 "활혈화어법(活血化瘀法)"과 결합(結合)하여 치료(治療)하면서 환자(患者)의 폐기능(肺氣能) 검사결과(檢査結果)의 변화(變化)를 추적(追跡)해, 그 치료효과(治療效果)에 대(對)한 평가(評價)를 내리는 작업(作業)으로 이루어졌다. 먼저 풍습과(風濕科)에 의뢰(依賴)하여 결체조직질병(結締組織疾病)에 간질성폐병(間質性肺病)이 병발(倂發)한 환자(患者)를 선별(選別)한 후(後)에, 서의치료(西醫治療) 통(通)해서 그 원발성(原發性) 질병(疾病)이 은정(隱靜)한 상태(狀態)에까지 이르도록 한 후(後), 필요(必要)한 최저량(最低量)의 서의약(西醫藥)만을 유지(維持)케 하였다. 환자(患者)의 의사(意舍)에 따라서 두 개의 조(組)로 나누어, 실험군(實驗群)은 중의(中醫)에서 회진(會診)하고, Raynaud 증후군(症候群)의 유무(有無)에 따라서, 당귀사역탕(當歸四逆湯) 혹(或)은 혈부축어탕(血府逐瘀湯)을 농축분제(濃縮粉劑)로 투여(投與)하며 연속(連續)하여 6개월간(個月間) 치료(治療)하였다. 대조군(對照群)의 경우(境遇)에는 중의(中醫)가 회진(會診)하지 않았다. 14개월(個月)동안 모두 실험군(實驗群) 23례(例)와 대조군(對照群) 16례(例)를 대상(對象)으로 연구(硏究)를 하였는데, 모두 여성환자(女性患者)였다. 압축성폐용량(壓軸性肺用量)(FVC), 폐총용량(肺總用量)(TCL), carbon monoxide에 대(對)한 폐(肺)의 확산능력(擴散能力)(DLCO), 그리고 폐포공기량(肺泡空氣量)(VA)에 대(對) DCLO의 비(比)를 지표(指標)로 삼아, 폐기능(肺氣能)의 손상정도(損傷程度)에 따라서 box plot으로 분석(分析)하고, 폐기능(肺氣能)의 손상(損傷)을 측정(測定)하는 시스템을 만들었다. 실험결과(實驗結果), 실험군(實驗群)이 대조군(對照群)에 비(比)해서 치료(治療) 전(前)보다 명현(明顯)한 개선(改善)이 있었다. 폐기능(肺氣能)을 검사(檢査)한 수치(數値)들을 일반적(一般的)으로 통계처리(統計處理)한 것을 응용(應用)하고, TCL과 FVC의 모형식(模型式)을 만든 결과(結果), 실험군(實驗群)에서 FVC가 치료과정(治療過程)의 기간(其間)과 정비례(正比例)하여 향상(向上)되고, 또한 치료효과(治療效果)가 명현(明顯)하게 나타나기 시작(始作)하는 시기(時期)가 중의(中醫) 치료과정(治療過程)을 거친 실험군(實驗群)의 제(第)12개(個)에서 DLCO와 DLCO/VA의 향상(向上)이 나타나는 시기(時期)와 거의 일치(一致)하는 것을 발견(發見)하였다.

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A Study on Estimation of a Beat Spectrum in a FMCW Radar (FMCW 레이다에서의 비트 스펙트럼 추정에 관한 연구)

  • Lee, Jong-Gil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.12
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    • pp.2511-2517
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    • 2009
  • Recently, a FMCW radar is used for the various purposes in the short range detection and tracking of targets. The main advantages of a FMCWradar are the comparative simplicity of implementation and the low peak power transmission characterizing the very low probability of signal interception. Since it uses the frequency modulated continuous wave for transmission and demodulation, the received beat frequency represents the range and Doppler information of targets. Detection and extraction of useful information from targets are performed in this beat frequency domain. Therefore, the resolution and accuracy in the estimation of a beat spectrum are very important. However, using the conventional FFT estimation method, the high resolution spectrum estimation with a low sidelobe level is not possible if the acquisition time is very short in receiving target echoes. This kind of problems deteriorates the detection performance of adjacent targets having the large magnitude differences in return echoes and also degrades the reliability of the extracted information. Therefore, in this paper, the model parameter estimation methods such as autoregressive and eigenvector spectrum estimation are applied to mitigate these problems. Also, simulation results are compared and analyzed for further improvement.

An Efficient Technique for Processing Frequent Updates in the R-tree (R-트리에서 빈번한 변경 질의 처리를 위한 효율적인 기법)

  • 권동섭;이상준;이석호
    • Journal of KIISE:Databases
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    • v.31 no.3
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    • pp.261-273
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    • 2004
  • Advances in information and communication technologies have been creating new classes of applications in the area of databases. For example, in moving object databases, which track positions of a lot of objects, or stream databases, which process data streams from a lot of sensors, data Processed in such database systems are usually changed very rapidly and continuously. However, traditional database systems have a problem in processing these rapidly and continuously changing data because they suppose that a data item stored in the database remains constant until It is explicitly modified. The problem becomes more serious in the R-tree, which is a typical index structure for multidimensional data, because modifying data in the R-tree can generate cascading node splits or merges. To process frequent updates more efficiently, we propose a novel update technique for the R-tree, which we call the leaf-update technique. If a new value of a data item lies within the leaf MBR that the data item belongs, the leaf-update technique changes the leaf node only, not whole of the tree. Using this leaf-update manner and the leaf-access hash table for direct access to leaf nodes, the proposed technique can reduce update cost greatly. In addition, the leaf-update technique can be adopted in diverse variants of the R-tree and various applications that use the R-tree since it is based on the R-tree and it guarantees the correctness of the R-tree. In this paper, we prove the effectiveness of the leaf-update techniques theoretically and present experimental results that show that our technique outperforms traditional one.

Effcient Neural Network Architecture for Fat Target Detection and Recognition (목표물의 고속 탐지 및 인식을 위한 효율적인 신경망 구조)

  • Weon, Yong-Kwan;Baek, Yong-Chang;Lee, Jeong-Su
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.10
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    • pp.2461-2469
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    • 1997
  • Target detection and recognition problems, in which neural networks are widely used, require translation invariant and real-time processing in addition to the requirements that general pattern recognition problems need. This paper presents a novel architecture that meets the requirements and explains effective methodology to train the network. The proposed neural network is an architectural extension of the shared-weight neural network that is composed of the feature extraction stage followed by the pattern recognition stage. Its feature extraction stage performs correlational operation on the input with a weight kernel, and the entire neural network can be considered a nonlinear correlation filter. Therefore, the output of the proposed neural network is correlational plane with peak values at the location of the target. The architecture of this neural network is suitable for implementing with parallel or distributed computers, and this fact allows the application to the problems which require realtime processing. Net training methodology to overcome the problem caused by unbalance of the number of targets and non-targets is also introduced. To verify the performance, the proposed network is applied to detection and recognition problem of a specific automobile driving around in a parking lot. The results show no false alarms and fast processing enough to track a target that moves as fast as about 190 km per hour.

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임진강대 석류석의 성장과 다변형작용의 시간적-공간적 관계

  • 김윤섭;조문섭;안진호
    • Proceedings of the Mineralogical Society of Korea Conference
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    • 2003.05a
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    • pp.51-51
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    • 2003
  • 임진강대의 변성이질암은 전형적인 바로비안형 변성분대를 보이며, 남쪽으로 갈수록 변성도가 증가하여 석류석$\longrightarrow$십자석$\longrightarrow$남정석 대를 정의한다. 우리는 반상변정의 성장과 여러번에 걸친 광역변형작용의 연관성을 밝히기 위해 광물의 반응관계와 성장순서 그리고 미구조(microstructure)를 -특히 석류석에 대해서- 연구하였다. 임진강대는 크게 세 번에 걸쳐 변형작용을 받은 것으로 해석된다: (1) 지각 두께의 증가에 수반된 압축변형작용 (D$_{n-1}$), (2) 주 엽리(Sn)를 만든 변형작용(Dn), 그리고 (3) 연성전단작용에 수반된 신장변형작용(D$_{n+1}$ ). 석류석대의 석류석 반상변정에서는 약간 휘어진 포유물 궤적(inclusion trail)이 주 엽리면에 대해 연속적이며, 이는 Dn과 동시기에 반상변정이 생성되었음을 지시한다. 이러한 석류석은 녹니석과 백운모로 구성된 주 엽리를 치환하면서 자라기 때문에, 녹니석+백운모+석영=석류석+흑운모+$H_2O$의 반응에 의해 만들어진 것으로 해석된다. 석류석 자형변정(idioblast)이 주 엽리를 자르면서 성장하기도 하는데, 이는 Dn 이후에도 석류석이 후구조(post-tectonic) 광물로 성장했음을 지시한다. 또한, 이러한 석류석은 흑운모를 치환하기 때문에, 동구조(syn-tectonic) 석류석의 생성반응에서와는 달리 흑운모가 반응물임을 알 수 있다. 한편, 십자석대의 석류석은 포유물 궤적에 의해 정의되는 S$_{n-1}$면이 주 엽리면과 사각을 이루며 단속적이기 때문에, D$_{n-1}$과 Dn 사이에 자란 것으로 해석된다. 이와는 대조적으로 십자석은 주 엽리를 치환하면서 자라고 있어서 Dn과 동시기 혹은 Dn 이후에 자랐을 것으로 해석된다..의 환경문제를 발생하지 않으며, 공정액에 첨가제를 투입하지 않으므로 순환형 친환경공정으로 각광받을 수 있다. 본 연구에서는 고온, 고농도의 NaOH 수용액의 처리에 적합한 막소재와 발생될 수 있는 제반 문제점 등을 파악하였고, 장기간의 실험을 거쳐 최적 투과 압력(Trans membrane pressue), 세정 조건 및 주기, 막재질에 있어서 보강하여야 할 Point, 최적 운전 조건들을 토출해 내었고, 향후 실제 Plant에 적용할 계획이다.는 양적으로 다른 두 가지의 유사한 마그마가 수반된 것으로 추정된다. 것으로 추정된다.를 사용하지 않음으로써 효과적이고 만족할 만한 심근보호 효과를 보였다.를 보였다.4주까지에서는 비교적 폐포는 정상적 구조를 유지하면서 부분적으로 소폐동맥 중막의 비후와 간질에 호산구 침윤의 소견이 특징적으로 관찰되었다. 결론: 분리 폐 관류는 정맥주입 방법에 비해 고농도의 cisplatin 투여로 인한 다른 장기에서의 농도 증가 없이 폐 조직에 약 50배 정도의 고농도 cisplatin을 투여할 수 있었으며, 또한 분리 폐 관류 시 cisplatin에 의한 직접적 폐 독성은 발견되지 않았다이 낮았으나 통계학적 의의는 없었다[10.0%(4/40) : 8.2%(20/244), p>0.05]. 결론: 비디오흉강경술에서 재발을 낮추기 위해 수술시 폐야 전체를 관찰하여 존재하는 폐기포를 놓치지 않는 것이 중요하며, 폐기포를 확인하지 못한 경우와 이차성 자연기흉에 대해서는 흉막유착술에 더 세심한 주의가 필요하다는 것을 확인하였다. 비디오흉강경수술은 통증이 적고, 입원기간이 짧고, 사회로의 복귀가 빠르며, 고위험군에 적용할 수 있고, 무엇보다도 미용상의 이점이 크다는 면에서 자연기흉에 대해 유용한 치료방법임에는 틀림이 없으나 개흉술에 비해 재발율이 높고 비용이 비싸다는 문제가 제기되고 있는 만큼 더 세심한 주의와 장기 추적관찰이 필요하리라 사료된다.전 도부타민 심초음파는 관상동맥우회로술 후

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Environmental Fate Tracking of Manure-borne NH3-N in Paddy Field Based on a Fugacity Model (Fugacity 모델에 기초한 논토양에서의 액비살포에 따른 암모니아성 질소 거동추적)

  • Kim, Mi-Sug;Kwak, Dong-Heui
    • Journal of Korean Society on Water Environment
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    • v.35 no.3
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    • pp.224-233
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    • 2019
  • Nitrogen components in liquid manure can reduce safety and quality of environment harmfully. To minimize the environmental risks of manure, understanding fate of manure in environment is necessary. This study aimed at investigating applicability of a simplified Level III fugacity model for simulating $NH_3-N$ component to analyze environmental fate and transport of $NH_3-N$ in liquid manure and to provide basis for improving management of N in the liquid manure system and for minimizing the environmental impacts of N. The model simulation conducted for four environmental compartments (air, water, soil, and rice plants) during rice-cropping to trace $NH_3-N$ component and provided applicability of the Level III fugacity model in studying the environmental fate of $NH_3-N$ in manure. Most of $NH_3-N$ was found in water body and in rice plants depending upon the physicochemical properties and proper removal processes. For more precise model results, the model is needed to modify with the detailed removal processes in each compartment and to collect proper and accurate information for input parameters. Further study should be about simulations of various N-typed fertilizers to compare with the liquid manure based on a modified and relatively simplified Level III fugacity model.

A Study of the Generational Cleavage in Welfare Attitudes: Differentiating Cohort Effect from Age Effect and Finding Its Factors (복지태도의 세대 간 균열 연구: 연령효과와 분리된 코호트 효과와 그 요인의 분석)

  • Jo, Nam Kyoung
    • 한국사회정책
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    • v.24 no.2
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    • pp.245-275
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    • 2017
  • It is attempted here to explain change in welfare attitudes for two decades in 10 countries with the cohort effect, especially differences in societal values between generations. It was found that for the last 20 years pro-welfare attitudes of the public has been strengthened, on which the generation has impact, more by the cohort effect than by the age effect, and that the Millennials/Y-generation are the strongest supporters for the state welfare. Value-differences between cohorts, as a background factor for the cohort effect on welfare attitudes, are clear but show a kind of linear trend from the older to the younger cohorts. As for the cohort effect on welfare attitudes, it is expected, at least for the short-term future, in the direction toward supporting the expansion of the state welfare. Korean welfare attitudes show an exceptional pattern - preferring income inequality as incentives, and at the same time, the expansion of governmental welfare responsibility, which echoes recent arguments of contradictoriness and non-class-orientedness of Korean welfare attitudes. Especially, Korean Millennials/Y-G shows this contradictory welfare attitudes the most strongly, which is unique between 10 countries in this study, implying their fierce competition is being internalized. It is expected that the contradictoriness of Korean welfare attitudes may limit its possibility to back up welfare expansion in Korea.

Zhuzi Learning, Yangming Learning, and Formation of "Gukhak": Genealogy of Subjectivity and Silsim (주자학과 양명학, 그리고 '국학'의 형성 - 주체성과 실심(實心)의 계보학 -)

  • Kim, Woo-hyung
    • The Journal of Korean Philosophical History
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    • no.58
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    • pp.307-336
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    • 2018
  • This paper traces the historical genealogy of the subjectivity and the silsim (實心, true mind) that appear in Jeong In-Bo's "gukhak" (國學, the national learning) thought and illuminates its characteristics. In the modern East Asian history of thought, the beginning of the emergence of subjectivity and the silsim as the main philosophical topic comes from the Neo-Confucianism of Song Dynasty in China. Cheng Yi is the first thinker to emphasize subjectivity and consciousness. Zhu Xi and Wang Yang-ming inherit the Neo-Confucian thought based on Cheng Yi's principle of subjectivity, but only show difference in methodology. In the Chosun Dynasty, Jeong Je-Doo and his School were one example of the Neo-Confucian spirit of subjectivity and the silsim. Although Jeong In-Bo (鄭寅普) belongs to Jeong Je-Doo's school of Ganghwa in the school curriculum, he has only used it methodologically since he believed that Yangming's learning is more effective in the awareness and practice of the silsim. Especially noteworthy is that the principle of subjectivity led Jeong In-Bo to follow the frame of Zhu Xi's moral theory. Jeong's claim that selfish desire (jasasim 自私心) should be controlled by a conscious mind (silsim) being aware of the right and 'ought to do' corresponds to Zhu Xi's view that the moral mind (dosim 道心) should be selected in the conflict situation between sensual desire (insim 人心) and moral consciousness so that the insim should be supervised by the dosim. Such ethics is a position to emphasize the inner motive and the sense of duty of conduct, and there is no fundamental difference in Zhu Xi and Wang Yang-ming. At least on this point, it is necessary to look at modern and contemporary Korean studies from the perspective of continuity, not discontinuity from Confucian tradition.

Behavioral responses and tolerance limits of wild goldeye rockfish Sebastes thompsoni to high temperature exposure (고 수온 노출에 따른 자연산 불볼락 Sebastes thompsoni의 행동반응 및 내성 한계)

  • Sung-Jin Yoon;Jin-Hyeok Park
    • Korean Journal of Environmental Biology
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    • v.40 no.3
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    • pp.247-254
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    • 2022
  • To investigate the tolerance limit and critical thermal maximum (CTM), behavioral responses of wild goldeye rockfish Sebastes thompsoni according to exposure to high water temperature were observed using a continuous behavior tracking system. As a result, behavioral index (BI) of S. thompsoni in each temperature (20.0, 25.0, and 30.0℃) showed a significant difference (p<0.05) when compared with the value measured in a stable condition of 15.0℃. The activity level of S. thompsoni exposed to 25.0℃ decreased sharply after 20 hours. Their rest time at the bottom of experiment chamber increased, and their normal swimming and metabolic activities were disturbed. In addition, at a high water temperature of 30.0℃, S. thompsoni reached the limit of resistance and showed a sub-lethal reaction of swimming behavior, with energy consumption in the body increased and all test organisms died. In conclusion, the eco-physiological response of S. thompsoni to water temperature varied greatly depending on the fluctuation range of the exposed temperature and the exposure time. In addition, the tolerance limit of S. thompsoni to high water temperature was predicted to be 25.0-30.0℃. The maximum critical thermal that had a great influence on the survival of this species was found to be around 30.0℃.