• The Journal of the Korean bone and joint tumor society
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• v.9 no.1
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• pp.101-104
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• 2003

Folope et al(1999) reported soft tissue giant cell tumor which was similar to malignant giant cell tumor in clinical, pathologic, and immunohistological aspect but represented low malignancy. We reported a 30-year-old female suffered from pain and palpable mass on the anterolateral aspect of the right knee for one year. Excisional biopsy from the lesion revealed some giant cells and polymorphous cells containing eosinophilic cytoplasm and vacuolated nucleus. Histopathologic findings of the lesion were consistent with soft tissue giant cell tumor of low malignant potential. Hereby, we report a case of soft tissue giant cell tumor of low malignant potential with a review of the literature.

• Journal of Chest Surgery
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• v.40 no.7 s.276
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• pp.526-528
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• 2007

A giant cell tumor of bone is a benign bone tumor, but has very high local recurrence rate and, very rarely metastasizes to the lung or a distant area. We report a case of a 29-year-old male patient presenting with a metastatic giant cell tumor of the soft tissue of the chest wall, who underwent a total resection of the radius for recurrence of the giant cell tumor. The tumor was not related to any bony structure of the thorax. We resected the tumor with a wide surgical margin. No evidence of malignancy was seen in the frozen and permanent pathological report.

• 대한족부족관절학회:학술대회논문집
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• 2008.11a
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• pp.9-10
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• 2008

• Journal of Convergence for Information Technology
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• v.11 no.12
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• pp.176-181
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• 2021

This study was conducted to confirm the effect of vibration on muscle activity in IASTM. The subjects were 20 healthy adults. The intervention applied in this study was IASTM applied to the biceps brachii muscle. In the case of the experimental group, unlike the control group, the vibration function was turned on when IASTM was applied. The interventions for each group were applied, and the muscle activity of the biceps brachii muscle was measured before and after the intervention. All measured values were calculated as %MVIC values, dependent t test and independent t test were performed and analyzed for comparisons. As a result of this study, only in the control group, the muscle activity of the biceps brachii muscle after the intervention was significantly decreased compared to before the intervention. When vibration is applied together with IASTM, the relaxation effect is reduced, which is considered to be inappropriate for treatment.

• The Journal of the Korean bone and joint tumor society
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• v.14 no.2
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• pp.119-124
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• 2008

Purpose: To present our experience with soft tissue reconstruction using anterolateral thigh free flap after resection of soft tissue sarcoma. Materials and Methods: Between January of 2003 and June of 2007, we treated 7 patients with soft tissue reconstruction using anterolateral thigh free flap after wide resection for soft tissue sarcoma. We retrospectively analyzed type and size of tumors, resection margin, size of defect after resection, time of operation, flap survival and complication. Results: The type of sarcoma was 3 synovial sarcoma, 2 malignant fibrous histiocytoma, 1 leimyosarcoma and 1 fibrosarcoma. The size of tumor varied from $3{\times}5\;cm$ to $7{\times}8\;cm$. The resection margins of tumors were negative in all cases. The size of soft tissue defect after resection varied from $6{\times}8\;cm$ to $15{\times}10\;cm$. The mean time of operation was 3.6 hours. All flaps were survived. Conclusion: Anterolateral thigh free flap appear to be ideal for reconstruction after wide resection of soft tissue sarcoma.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1993.05a
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• pp.99-99
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• 1993

Radiography of nasopharynx are routinely performed for nasopharyngeal soft tissue changes. Although CT scan is widely performed nowadays, the value of lateral neck radiograph is still important to detect the masses in the nasopharynx. The purpose of this study was to establish the constitution of the normal dimension of the nasopharyngeal soft tissue on the lateral neck radiograph and make a parameter of the nasopharyngeal soft tissue hypertrophy. We have made various measurements of the thickness of the nasopharyngeal soft tissue on the lateral skull films in 214 Korean adults (109 males and 104 females). We found that the diameter of the nasopharyngeal soft tissue was decreased by age and the value of males were always greater than that of females and the thickness of the roof was always less than the posterior wall.

• The Journal of the Korean bone and joint tumor society
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• v.13 no.2
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• pp.135-141
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• 2007

Nodular faciitis is generally considered to be benign proliferation of fibroblasts and myoblasts, and it measures dimension up to 3cm. The characteristics such as rapid growth, abundant cellularity, and mitotic activity occasionally cause these lesions to mimic sarcoma. The authors experienced two cases of nodular fasciitis of the thigh, which were unusually large with dimension of more than 5cm. All of these two cases mimicked sarcoma and one of two cases, which initially mimicked sarcoma clinically and histologically in our hospital, was finally diagnosed as nodular fasciitis after requesting external consultation to several experienced pathologists. All of two cases had no evidence of recurrence at 2 years postoperatively. The lesions of unusually large dimension such as in our cases must be included in the differential diagnosis of soft tissue sarcoma. So we report two cases of nodular fasciitis of the thigh with a review of the current literature.

• The Journal of the Korean bone and joint tumor society
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• v.14 no.2
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• pp.106-118
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• 2008

Purpose: Disturbed cell cycle regulatory proteins are key events underlying the development and/or progression of human malignancies. The aim of this study is to evaluate the protein expression status involved in G1/S cell cycle in human soft tissue sarcoma. Materials and Methods: We simultaneously evaluated the expression of Cyclin D1, Cyclin E, CDK4, CDK2, p16, p27, Rb, E2F1, p53 and Ki-67 by immunohistochemistry in 43 cases of soft tissue sarcoma Results: The Cyclin D1, Cyclin E, CDK4, CDK2, E2F1, and p53 were expressed in 25 (58.1%), 18 (41.9%), 13 (30.2%), 33 (76.7%), 20 (46.5%), and 18 cases (41.9%). The p16, p27, and Rb expressions were decreased in 26 (60.5%), 22 (51.2%) and 19 cases (44.2%). All of the cases showed alterations of more than one out of the above proteins. The increased Cyclin E expression and Ki-67 labeling index (LI) were significantly associated with histologic grade. The Cyclin E and E2F-1 expressions were increased in relapsed cases and the CDK4 expression was increased in cases of metastasis. Conclusion: Alterations of G1/S cell cycle regulatory proteins may play an important role in the tumoriogensis of soft tissue sarcomas. Our results suggest that increased expressions of Cyclin E, E2F1, and CDK4 were associated with tumor relapse or metastasis and could be considered as parameters of prognosis of soft tissue sarcoma.

• The Journal of the Korean bone and joint tumor society
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• v.9 no.1
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• pp.69-76
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• 2003

Purpose: This study was designed to provide the data base for the diagnosis and treatment of the foot tumor by investigation of the clinical and pathological characteristics and distribution of the foot tumor. Materials and Methods: 142 foot tumors of 141 patients were studied. All patients were diagnosed with surgical biopsy. We investigated clinical and pathological characteristics and epidemiologic distribution of the foot tumor by reviewing the medical records and imaging materials. The location of the tumors were classified with zone of Kirby et al. Results: 75 patients were female and 66 were male. The average age of the patients was 33.2 years old. Benign soft tissue tumors were the most as 68 cases, and followed by 57 benign bone tumors, 12 malignant soft tissue tumors and 5 malignant bone tumors. Ganglia were the most in benign soft tissue tumors as 36 cases, subungual exostoses in benign bone tumors as 18, squamous cell carcinomas in malignant soft tissue tumors as 7, and metastatic lung cancers in malignant bone tumors as 2. The rate of pain complaints was the highest in malignant bone tumors, the duration of symptom was longest in benign soft tissue tumors, and the size of the tumor was the biggest in malignant bone tumors. Neurological symptoms were found in only 3 benign soft tissue tumors. For the zonal distribution, zone 5 was the most in 59 cases and zone 4 was the least as 10. The most numbers of the benign bone tumors located in zone 5, of benign soft tissue tumors in zone 1, of malignant bone tumors in zone 1 and 2, and of malignant soft tissue tumors in zone 5. The methods of surgical treatment included intralesional or marginal resection, curettage with or without bone graft, toe amputation, below knee amputation and limb salvage. Conclusion: The tumors of the foot were rare and various, and mostly benign (88%), but we can do proper treatment of those tumors without excluding malignant tumors by considering the age of patients, pain, duration of symptom, size of the tumors, and zonal distribution.

• Journal of Yeungnam Medical Science
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• v.14 no.1
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• pp.227-236
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• 1997

발꿈치는 신체의 다른부위에 비하여 엄청난 하중을 지탱하고 있으며, 주행시에는 막대한 전단력을 받으므로 그 재건에 있어서 어려운 점이 있다. 그 동안 발꿈치의 연부조직 결손을 재건하기 위한 많은 방법들이 개발되어 왔지만, 비교적 큰 발꿈치의 연부조직 결손을 재건하는 것은 아직도 쉬운 일이 아니다. 이처럼 큰 결손의 재건에는 주로 유리 피판술을 이용한 재건술을 사용하는데, 그 중에서도 광배근, 복직근, 대퇴박근 등의 근육을 이용하는 방법이 최근에 많이 이용되고 있다. 이와 같은 유리 근 피판에 피부이식을 이용하는 발꿈치 재건술은 표재성 감각기능을 재건하지 못하는 것이 단점으로 지적되고 있으나, 보행 또는 주행시 발꿈치에 가해지는 압력과 전단력을 효과적으로 견디어 낼 뿐아니라, 외관상으로도 정상에 가까운 발꿈치를 재건할 수가 있어서 좋은 방법으로 인정되고 있다. 특히, 대퇴박근은 피판을 비교적 쉽게 채취할 수 있고, 공여부에 기능적인 장애나 심한 변형을 남기지 않아서 좋은 방법이라 생각된다. 다만 크기가 비교적 작아서, 발등이나 족관절 상부에까지 이르는 광범위한 연부조직 결손에서는 사용할 수 없는 점이 아쉽다. 저자는 비교적 가늘고 긴, 대퇴박근의 형태적 특징을 최대한 이용하여, 결손부의 다양한 형태 및 크기에 따라 대퇴박근을 말발굽형, 나선형, S-자형 등으로 적절히 형상화하여 발꿈치 결손을 효과적으로 재건하는 방법을 고안하였다. 또한, 공여부에 긴 선상 반흔이 남는 것을 피하기 위하여 두 개의 작은 절개를 통해서 대퇴박근을 채취하였다. 이 방법을 이용하여 영남대학교 의과대학 성형외과학 교실에서는 1993년 이후부터 7명의 비교적 큰 발꿈치의 연부조직 결손 환자를 대상으로 유리 대퇴박근 피판술을 이용한 재건술로 성공적인 결과를 얻을 수 있었다.