• Child Health Nursing Research
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• v.19 no.1
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• pp.21-28
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• 2013

Purpose: This study was done to provide basic data for developing nursing interventions to enhance quality of life of pediatric patients with cancer (children and adolescents) by examining the quality of life and related factors. Methods: Participants were 134; 67 pediatric patients and 67 parents. The PedsQL$^{TM}$ 3.0 Cancer Module was employed to measure quality of life in the participants. The related factors included general and clinical characteristics of the participants. Results: Mean score for quality of life in the patients was 75.07, and mean score for patient quality of life as perceived by their parents was 64.40. Among the quality of life subscales, treatment anxiety had the highest score whereas nausea had the lowest score. Mean score in adolescent patients (13-18 years of age) was 71.62, lower than the 78.04 for child patients (8-12 years of age). Regarding general and clinical characteristics of the participants, there were no significant differences in the scores. Conclusion: The results indicate that there is difference in perception of quality of life between patients and their parents, and between children and adolescents and these differences should be taken into account when planning and providing nursing care.

• Korean Journal of Health Psychology
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• v.16 no.3
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• pp.483-500
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• 2011

Since the introductionof modern therapies, more children with cancer have survived their illness. As a result, an interest in the degree of adjustment achieved by cancer survivors has increased. In this study, quality of life and behavior problemsof child and adolescent cancer survivors were compared with those of healthy controls. Also, the patternsof the discrepancy between parent-report and self-report were compared. Childhood cancer survivors aged 8-18 and their mothers were participated in the study. Parent and self report versions of PedQL were administered to assess the quality of life. K-CBCL and K-YSR were further completed to assess internalizing and externalizing behavior problem. Results suggested that cancer survivors generally showed lower quality of life in physical and social domains and more internalizing behavior problem than healthy control group. However, the results were affected by the domain, age group, and informant. The pattern of discrepancy between parent and self report was similar. All parents reported higher levelsof quality of life and lower levels of behavior problems compared to the self reports of their siblings. In assessing internalizing problem behaviors, cancer survivor group showed greater discrepancy than the healthy control group.The implications, limitations, and directions for future research were also discussed.

• Journal of dental hygiene science
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• v.14 no.3
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• pp.269-275
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• 2014

Recently, there are lots methodologies to improve the quality of research in medical and public health fields. One of them is to checking a process of research with a reporting guideline before reporting paper. Especially, reporting guideline for randomized controlled trials (RCTs) is the consolidated standards of reporting trials (CONSORT). Therefore, this review describes the latest version of the CONSORT statement, CONSORT 2010, including intent, background, and contents of this. The CONSORT statement comprises a checklist of essential items that should be included in reports of RCTs and a diagram for documenting the flow of participants through a trial. This report guideline aims at providing guidance to authors about how to improve the reporting of their trials. As consulting the CONSORT, authors could be strictly reported about research methods and results. From this review, we expect to elevate the quality of such research about dental hygiene and to establish the foundation for evidence-based dental hygiene.

• Korean Journal of Animal Reproduction
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• v.19 no.4
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• pp.271-281
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• 1996

1960년대에 본격적인 연구가 시도된 난세포질내 정자직접주입법(Intracytoplasmic Sperm Injection ; ICSI)은 1976년에는 Uehara 등에 의한 hamster의 연구에서 최초로 전핵의 형성에까지 성공하였다. 이후 계속된 연구를 통하여 여러 동물종에서 이 방법에 의한 난자의 수정 및 배발달에 성공하여, 1988년에 토끼, 1991년에 소, 1995년에는 생쥐에서 산자의 생산에 성공하였다. 한편, 사람에 있어서는 1988년 Lanzendorf 등에 의해 최초로 사람난자가 난세포질내 정자직접주입법에 의해 수정에 성공한 것이 보고되었으며, 1992년에는 Palermo 등에 의해 이 방법에 의해 수정된 수정란 이식을 통한 임신 및 성공적인 분만이 보고되었다. 난세포질내 정자직접주입법에 있어서는 정자의 운동성 및 첨체반응 등의 유무가 수정에 관여하는 중요한 요인이 아닌 것으로 알려지고 있으며, 성숙한 정자가 아닌 정소상체(미부-두부)정자 혹은 정소내의 미성숙정자를 사용하여 난세포질내 정자직접주입법을 시행하여도 수정 및 임신이 가능한 것으로 보고되었다. 또한 정자세포(spematid)나 원형정자세포(round spermatid)를 수정과 배발달이 관찰되었으며 사람에 있어서는 분만까지 성공하였다. 현재까지 이 난세포질내 정자직접주입법은 학술적으로는 난자-정자가 결합하는 기전을 밝히는 연구에 이용되어 왔으며, 임상적으로는 시험관아기시술에 있어서 정자의 기능, 수 등이 문제가 되어 수정이 어려운 남성불임환자에게 적용하여 좋은 성과를 거두어 왔다. 향후 이 기술은 유전자진단이나 남성불임환자의 처치에 폭넓게 사용될 것으로 기대된다.

• Quality Improvement in Health Care
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• v.12 no.2
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• pp.35-40
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• 2006

체계적 고찰은 명확히 정의된 문헌검색에 기반하고, 결정된 기준(criteria)을 이용하여 선택된 문헌의 질을 평가하며, 타당성이 입증된 방법으로 분석을 시행하는 리뷰의 한 형태이다. 체계적 고찰은 (1)답을 얻고자 하는 질문을 공식화 하고 이에 대한 프로토콜을 작성하고, (2)해당 질문에 대한 일차 연구를 찾아서 포함시키고 (3)자료의 질을 평가하고, (4)자료를 추출하여 뽑고, (5)자료를 분석하며, (6)결과를 해석하고 보고서를 작성하는 순서로 이루어진다 하지만 체계적 고찰 혹은 메타분석이 모든 문제에 대한 해결책은 아니다. 메타분석이 수행되었다고 하더라도 질이 나쁜 연구가 포함되거나 질 문제를 무시한 경우, 이질성에 대해 적절한 주의를 기울이지 못할 때, 무차별적인 자료 병합으로 결론이 정확하지 않은 경우, 출판 비뚤림, 시간 지체 비뚤림, 이중 출판 비뚤림, 언어 비뚤림, 결과 보고 비뚤림과 같은 보고 비뚤림이 문제가 되는 경우에는 메타분석 혹은 체계적 고찰이 잘못된 결론으로 도달하도록 할 수 있다. 따라서 올바른 방법론에 기초한 체계적 고찰만이 현존하는 모든 근거를 결합하여 올바른 결론으로 이끌 수 있다.

• The Journal of Small Business Innovation
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• v.19 no.1
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• pp.59-84
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• 2016

Using an international setting, this study investigates the relation between cash holdings and financial reporting quality, measured by accruals quality. Empirical results show that the balance of cash holdings is positively related to the opacity of financial reporting in non-U.S. international markets. The relation becomes stronger as the strength of investor protection increases, implying that precautionary motives, instead of agency motives, drive the increase of cash holdings of opaque firms. In addition, the positive relation is stronger for discretionary accruals quality. The decomposition of the aspects of investor protection shows that public enforcement through regulation authorities is the main driver of the positive relation between cash holdings and the opacity of financial reporting.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.158-167
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• 2016

This study was conducted to evaluate the quality of meta-analysis of social work in South Korea using the Assessment of Multiple Systematic Review (AMSTAR). Electronic databases including the Korean Studies Information Service System (KISS), DBpia, and RISS4U were searched for 'meta-analysis', 'social work', and 'social welfare' from 2000 to December 2015, and 42 meta-analysis studies were included. Data were analyzed using descriptive statistics, t-tests, and ANOVA. The mean score for AMSTAR evaluation was $4.766{\pm}1.66$, while 19 studies (45.2%) were classified at the low-quality level, and 22 (52.4%) were at the moderate-quality level. The scores of quality assessment were analyzed by publication year, participants, number of studies included, number of DB, reporting study quality, extraction diagram and topics. The findings indicated that the following changes should be implemented to improve the quality and reliability of meta-analysis results in social work research: 1) common reporting guidelines should be provided for the social work field, 2) quality analyses of each study should be conducted to achieve a high level of evidence of effectiveness of social work interventions, 3) the characteristics of the included studies should be provided, and 4) a consensus and procedure based on at least two independent data extractors should be reported.

• Korean Journal of Animal Reproduction
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• v.19 no.3
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• pp.205-216
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• 1995

Microtubules와 micrfilaments는 포유동물 난자이 주요한 세포 구조물들로, 이들은 난자의 성숙, 수정 및 배발달시 핵질의 이동과 세포질 분열에 직접 관여하는 것으로 알려져 왔다. 난자내 세포구조물의 정확한 움직임은 정상적인 배 발달을 위해 필수적이다. Microtubules는 $\alpha$, $\beta$- bubulin이 서로 연결되어 이루어져 있으며, 수정시 웅성.자성전핵 움직임과 세포분열시, 유사 및 감수분열시 그 역할을 한다. 생쥐를 제외한 대부분의 동물에서 microbubules의 역할은 수정시 정자가 centrosome을 난자내로 이전하여 sperm aster를 형성함으로써 시작된다고 보고되고 있다. 따라서 정자의 도움없이 배발달이 일어나는 단위발생시 microbubules의 형성은 연구들 사이에 흥미로운 연구대상이 되고 있다. 한편 microfilaments는 세포분열시 세포질을 분할하는 기계적인 역할을 하는 것으로 알려져 있으며, 최근 생쥐 난자에서는 정자의 난자내 융합과 웅성 및 자성 전핵의 이동에 관여한다고 보고되고 있다. 포유동물 난자의 체외성숙, 체외수정을 유도할 때 여러 가지 비정상적인 핵움직임과 세포분열이 관찰되어지고, 낮은 배발달율이 보고되고 있는데, 최근 연구자들은 세포구조물, 즉 microtubules와 microfilaments의 비정상적인 역할에서 기인한다고 보고 있다. 따라서 포유동물 난자의 성숙.수정 및 단위발생시 세포구조물의 움직임과 역할 및 상호관계에 대한 정확한 이해는 체외수정율 및 배발달 향상에 중요한 기초자료로 이용되리라고 본다.

• The Journal of Korean Academy of Sensory Integration
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• v.21 no.2
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• pp.45-57
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• 2023

Objective : The purpose of this study was to investigate the concurrent validity of the self- and proxy-report versions of the KIDSCREEN-10 quality of life questionnaire. Methods : A total of nine children and nine parents were selected to represent a cohort registered for a school-based wellness program. Two versions of the KIDSCREEN-10 questionnaire (self- and proxy reports) were administered to the children and their parents. The Rasch rating scale model was applied to determine the dimensionality and item difficulty of the two versions of the questionnaire. Moreover, the item-person matching map and Spearman's rho were compared to confirm the concurrent validity of the two versions. Results : All items, except four items (i.e., autonomy, home life, concentration/learning, and peers/social support), fit the Rasch rating scale model of the children's self-report version of the questionnaire. With regard to the parent's proxy-report version, two items misfit the model. While the items of the self- and proxy-report versions showed similar item difficulties, the parents had a tendency to be more severe in their ratings than the children. The correlation between the two versions was relatively low (Spearman's rho = .533, p > .05). The scatterplots between the two versions showed differences in the item difficulties of the physical and psychological well-being and self-perception items. Conclusion : These findings suggest that the three identified items should be taken into consideration when measuring children's health-related quality of life using the KIDSCREEN-10 questionnaire.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.3 no.2
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• pp.157-161
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• 1993

결정화 유리에서의 결정질 양의 측정, 혹은 소결체에서의 잔류 유리량을 측정할 때 유용한 방법을 찾아내기 위하여 현재까지 보고되어 있는 방법중에서 XRD를 이용한 Ohlberg의 방법과 Wakelin등의 방법을 이용하여 코디어라이트 조성의 유리와 α-코디어라이트의 혼합물에 대하여 결정질 양을 측정하였다. Ohlberg의 방법은 한 각도에서 측정하는 경우, 약 4∼5%의 오차를, 4각도에서 측정하여 평균한 경우에는 2∼3%의 오차를 보였으며, Wakelin등의 방법은 실험 양이 많았지만 2∼3%의 오차를 보였다.