• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.1
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• pp.145-154
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• 2006

A man visited the Dept. of Oriental Medical Ophthalmology & Otolaryngology & Dermatology Hospital, Dong-eui University with the dermatitis exfoliativa by drug eruption. He was suffering from the whole body itching, rubefaction, edema, scale and the feeling a chill. The drug eruption's cause assumed antibiotics. We treated a patient with Oriental Medicines(the herbal medicine of internal use and external use), aroma oils and acupuncture. After four days or so, the itching, rubefaction, edema of the skin was recovered remarkably. After one weeks or so, the scale of the skin disease was improved remarkably, we think that these are good cases to treat with Oriental Medicine, Yeongyopaedog-san. We suggest that Oriental Herb medicines have an effect with the dermatitis exfoliativa and the drug eruption.

• The Journal of Korean Medicine
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• v.34 no.3
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• pp.86-95
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• 2013

Objectives: Sprague-Dawley rats were fed with high fat diet, and atherogenic changes were seen in the aorta. However, when Sprague-Dawley rats were fed with a high fat diet and administered Youngyopaedoc-san together, these atherogenic changes were rarely seen. This study was aimed to find the inflammatory marker level changes in Sprague-Dawley rats with Youngyopaedoc-san-related anti-atherogenic effect. Methods: The extract from Youngyopaedoc-san was made by the pharmacy department of Kyung-hee Oriental Medical Hospital. The animals were divided into five groups: normal diet, high fat diet, high fat diet with Youngyopaedoc-san, high fat diet with Vytorin, and high fat diet with Youngyopaedoc-san and Vytorin. A light microscopic image of a cross section taken from the aorta of the Sprague-Dawley rat was analyzed. We compared inflammatory marker levels among the five groups. Results: The complex of Youngyopaedoc-san and Vytorin has more anti-atherogenic effects in the aorta of Sprague-Dawley rats fed with high fat diet than Vytorin alone. Youngyopaedoc-san has inhibitory effect on the increase of IFN-${\gamma}$ and IL-2 levels. The difference on eosinophil levels of each group was statistically significant, but the eosinophil level of each group was within normal limits, so the difference on eosinophil levels was not clinically significant. Conclusions: Youngyopaedoc-san-related anti-atherogenic effect could be a result of inhibitory mechanism on IFN-${\gamma}$ and IL-2.