• Title/Summary/Keyword: 양성적

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Endoscopic Therapy for Pancreatic Benign Neoplasms (췌장 양성 종양의 내시경적 치료)

  • Hwang, Jun Seong;Ko, Sung Woo
    • Journal of Digestive Cancer Research
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    • v.9 no.1
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    • pp.25-32
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    • 2021
  • Since Endoscopic ultrasound (EUS) was introduced in the 1980s, EUS has evolved from a diagnostic tool to a therapeutic modality for patients with pancreatic neoplasms. Traditionally, treatment policy of pancreatic benign neoplasms (PBN) has been a dichotomous approach to observation or surgery. However, EUS guided treatment provides an alternative option with minimally invasiveness for patients with PBN. This review aimed to provide the role of EUS guided treatment for PBN.

How Reliable is Sputum PCR Test in the Diagnosis of Pulmonary Tuberculosis When Sputum Smear is Negative? (객담 결핵균 도말검사가 음성일때 중합효소연쇄반응검사와 진단적 신뢰도에 관한 연구)

  • Baek, Seung-Hoon;Lee, Jae-Myung;Kang, Min-Jong;Son, Jee-Woong;Lee, Seung-Joon;Kim, Dong-Gyu;Lee, Myung-Goo;Hyun, In-Gyu;Jung, Ki-Suck;Lee, Kyung-Wha;Joe, Hyun-Chan
    • Tuberculosis and Respiratory Diseases
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    • v.50 no.2
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    • pp.222-228
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    • 2001
  • Backgrounds : Recent technological developments have introduced a new method to identifying M. tuberculosis complex DNA in clinical samples directly. The direct amplification test (DAT) is approved for identifying M. tuberculosis complex in respiratory specimens that are smear-positive for acid-fast bacilli (AFB). When there is a discrepancy between the AFB smear and DAT, no information on their clinical utility is currently available. In this study, the diagnostic reliability of DAT was investigated in suspected pulmonary tuberculosis patients whose sputum AFB smear was negative. Methods : From June 1, 1998 through May 30, 1999, 909 patients with presumed active pulmonary tuberculosis were enrolled. A sputum AFB stain, culture, DAT and/or biopsy were performed. Using the criteria of clinical tuberculosis or confirmed tuberculosis, the positive predictive value of DAT in diagnosing pulmonary tuberculosis was investigated. Results : The positive predictive value of DAT was 82.1% by the clinically active tuberculosis criteria. However, it decreased to 61.5% when diagnosis was restricted to only to culture positive or biopsy proven cases. The false positive rate of DAT was 18.0%. Conclusion : The DAT is a valuable diagnostic method in suspected patients whose sputum AFB is was negative.

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Dynamic Efficiency Analysis of Korean HRD Programs using Data Envelopment Analysis (DEA 방법론 활용을 통한 국가 HRD사업에 대한 동태적 효율성 분석)

  • Lee, Jung-Mann
    • Journal of Digital Convergence
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    • v.10 no.2
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    • pp.63-71
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    • 2012
  • This paper investigates efficiency analysis to IT HRD programs in the dynamic perspective. First, empirical result shows that government fund of IT research center is significantly associated with SCI thesis and the more trial goods and SW development is connected with the more patent and technology transfer. Second, ITRC program has been operated efficiently since 2000. Finally, dynamic efficiency analysis implicates that ITRC program is more efficient than other IT SoC program and foreign student support program. The reason why ITRC program is more efficient is generated not from the effect of imitation by catch-up strategy to developed HRD programs, but new operation system introducing and utilizing HRD performance system.

양성전분을 이용한 신문용지의 품질개선 및 생산성 향상

  • Lee, Hak-Rae;Ryu, Hun;Ham, Chung-Hyeon;Choi, Cheol-Hui;Jo, Seok-Cheol
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 1999.04a
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    • pp.33-33
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    • 1999
  • 고지 사용율을 증가시킴으로써 원가 절감을 모색하고 있는 국내 신문용지 생산업체에서 는 보류도와 탈수성 저하에 따른 생산성 악화가 발생하고 있을 뿐 아니라 제품의 강도 및 인쇄적성 저하라는 문제를 극복하는 것이 매우 중요한 과제로 대두되고 있다. 또 신문용지 생산공정의 수질이 악화됨에 따라서 사용되는 화학첨가제의 효능이 크게 감소하는 문제를 지니고 있다. 적합한 양성전분과 이러한 문제를 종합적으로 해결하기 위한 방안으로 신문용지 생산에 이의 적용기술을 모색하였다. 전기전도도가 4000 $\mu\textrm{s}$/cm인 신문용지 지료를 이용하여 DS 0.03인 저치환 양성 전분의 보류도 증가효과를 평가한 결과 양성전분을 사용하지 않은 경우에 비하여 보류도 증가율이 6 6%로 낮게 나타났으나, DS 0.06인 전분은 보류도 증가율이 21%로 향상효과가 높게 나타났 다. 또 양성전분의 치환도가 증가할수록 인장지수, 내부결합강도, 표면강도 향상 효과도 증 가되는 결과를 얻을 수 있었다. 가교 처리를 실시한 치환도 0.08 및 0.1의 습식양성전분의 경우에는 미세분 보류도, 여수도, 탁도 등에 큰 효과를 나타내지 않았다. 경우 보류도가 각 확인하였으며,이 건식방법으로 제조된 치환도 0.08 빛 0.15인 양성 전분을 0.5% 첨가할 각 16%, 21% 증가되어 적은 첨가량에서도 보류향상 효과가 높다는 것을 러한 효과는 여수도 및 양이온 요구량 측정을 통하여 재확인되었다. 저치환 양성전분의 성능을 개선시키기 위한 방법으로서 비이온성 천연고분자를 활용하 는 방안을 검토한 결과 비이온성 천연고분자를 병용함에 따라 보류도 증가율이 탁월하게 개 선되었으며, 인장지수, 내부결합강도, 표면강도 등에서도 같은 효과를 얻을 수 있었다.

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A Rapid Method for Monitoring of Gram-positive Bacteria in Wastewater Treatment Systems (폐수처리시스템에서의 그람 양성 세균 모니터링 방법)

  • Nam, Ji-Hyun;Bae, Woo-Keun;Lee, Dong-Hun
    • Korean Journal of Microbiology
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    • v.47 no.1
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    • pp.50-55
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    • 2011
  • A simple and rapid method was developed for monitoring of Gram-positive bacteria in the wastewater treatment system. Culture suspensions of 4 Gram-positive and 4 Gram-negative strains were filtrated and stained with a polyethersulfone membrane filter and Toluidine Blue-O. To establish quantitative color image analysis, the intensity value of RGB (red-green-blue) color of a scanned filter image was analyzed with a photographic program. Red and green color values of Gram-positive bacteria were higher than those of Gram-negative bacteria. This method was applied to the activated sludge mixed with the Gram-positive bacteria. Although evaluation was difficult due to the irregular size and shape of flocs, the population of Gram-positive bacteria in the activated sludge could be monitored with floc dispersion technique. The more amounts of Gram-positive bacteria in the activated sludge led to the increase of red and green color values. This method provides a rapid and quantitative measurement of Gram-positive bacteria within the wastewater treatment systems.

Derivation of Creative SW HRD Policy Using Analytic Hierarchy Process (계층분석을 활용한 창의적 SW인재양성 정책방향 도출)

  • Lee, Jung Mann;Rim, Myung Hwan
    • Journal of Digital Convergence
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    • v.11 no.10
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    • pp.95-102
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    • 2013
  • The paradigm of SW industry has been rapidly changing into mobile and cloud technology environment. Research model based on PEST-SWOT analysis was employed to derive internal and external factors connected with PEST factors through analyzing the current status and problems of SW HRD system in Korea. Survey was conducted by 20 experts who are involved in SW companies, university, and R&D research institute using AHP(Analytic Hierarchy Process) model. The empirical result showed that SW fusion HRD, creativity-oriented university education in the field of software, global education and exchange, and revitalization of SW venture ecosystem are derived as policy visions of SW HRD for smart industry ecosystem. Another findings are that SW fusion HRD, revitalization of SW venture ecosystem, Job Creation through revitalization of SW start-up, Creation of coexistence between SW large enterprises and SMEs, creativity-oriented university education in the field of software, and global education and exchange are presented in order in terms of the importance of policy priority.

A Case Study of Human Resource Nurturing Achievements through Industry-University Cooperation (산학협력을 통한 인력양성 성과도출 사례 연구)

  • Han, JungSoo
    • Journal of Internet of Things and Convergence
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    • v.8 no.5
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    • pp.41-46
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    • 2022
  • This study analyzed the results and implications of the industry-university cooperation human resource nurturing process based on the I-O model for the Motion Graphics major and the Global Hotelier major in Baek seok University. In this study, based on the analysis of the human resources training performance through industry-university cooperation in the motion graphics and hotelier fields for 5 years, what kind of efforts were made for successful human resource training, and the level of performance was analyzed and improvement points were suggested. In this study, four strategies were set for successful industry-university-tailored human resource nurturing: student-industry matching through industry participation in education, industry-university integrated education, education quality advancement, and customized education infrastructure construction. As a result of the analysis, customized human resource training should first be developed through industry demand survey and a mirror-type practice room should be built to fit the corporate environment. Second, it was found that it is possible to be individual only if there is an active participation of industry experts throughout the curriculum such as subjects and non-subjects.

Detection of Antibody to Hepatitis C Virus in Psychiatric Inpatients (정신과(精神科) 입원(入院) 환자(患者)의 C형(型) 간염(肝炎) 항체(抗體) 양성솔(陽性率))

  • Cheon, Jin-Sook;Han, Ho-Sung
    • Korean Journal of Biological Psychiatry
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    • v.2 no.1
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    • pp.100-106
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    • 1995
  • Antibodies to hepatitis C drew attention because of high morbidity to chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV was known to be transmitted by transfusion, sexual behavior and parenteral drug use. However, some kind of autoimmune mechanism was suggested to be involved in the genesis of HCV-induced liver diseases. We hypothesized the prevalence of having anti-HCV might be higher in psychiatric patients rather than general population because of the characteristic route of transmission. Using Abbott HCV BA kit, anti-HCV was detected in the sera of 113 psychiatric inpatients from early December in 1992 to late May in 1994. The Positivity of anti-HCY was significantly(P<0.05) higher among psychiatric inpatients(10.6%) than in healthy controls(3.0%). There were no disease specificity among psychiatric inpatients who had anti-HCV, though alcoholics tended to have more anti-HCV. We couldn't find any significant correlation of anti-HCV with age, seasons of birth, lymphocytes (%) and liver function.

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Influence of Environmental Living Standards on Helicobacter pylori Infection in Korean Elementary School Children (서울 지역 초등학생의 생활환경과 Helicobacter pylori 양성률)

  • Kim, Je-Woo;Kim, Hyo-Shin;Chung, Ki-Sup
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.4 no.1
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    • pp.10-17
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    • 2001
  • Purpose: We measured anti-H. pylori IgG in Korean elementary school children living in Shinchon area of Seoul, Korea to evaluate the influence of environmental living standards on H. pylori infection. Methods: IgG antibodies to H. pylori were measured in plasma using a commercial ELISA kit (GAP IgG Helicobacter pylori, Bio-Rad Laboratories Inc., Hercules, CA, USA). Information on environmental status such as place of birth, parental income, type of housing, number of persons in the household, parents' occupation, family history of peptic ulcer disease and gastric cancer was obtained. Statistical analysis was done by Chi-square and logistic regression test using SPSS $7.0^{TM}$ for Windows. Results: Study subjects consisted of 571 children, and the age distribution ranged from 6.0 to 13.6 years with a mean of $9.6{\pm}1.8$ years. Male-to-female ratio was 1.1:1. The seropositive rates of H. pylori infection ranged from 10.4% in children aged 6 years to 30.9% in 12 year-old group, overall 16.8%. The prevalence of H. pylori infection progressively increased with age, but there was no significant difference in seropositive rates among children in different age groups (p=0.06). Seropositive rates of anti-H. pylori IgG on the basis of gender, place of birth, parental income, type of housing, parents' occupation, family history of peptic ulcer disease and gastric cancer showed no statistically significant difference. Interestingly, however, seropositive rate of anti-H. pylori IgG showed statistical significance in relation to number of persons in the household (p=0.003; Odds ratio 1.50 by logistic regression test). Conclusion: These results suggest that number of persons in the household is the most important factor among environmental living standards, and that risk of H. pylori infection increases by increment of 1.5 times as the number of persons in the household increases by one.

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Prediction of Regional Metastasis by the Expression of Lymphangiogenic Factors in Micropapillary Thyroid Carcinoma (미세갑상선유두상암종에서 림프관 생성인자 확인을 통한 림프절 전이의 예측)

  • Lee, Sung-Bu;Choi, Seung-Ho;Nam, Soon-Yuhl;Cho, Kyung-Ja;Kim, Sang-Yoon
    • Korean Journal of Head & Neck Oncology
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    • v.27 no.1
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    • pp.32-37
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    • 2011
  • 서 론 : 미세갑상선유두상암종 환자에서 불필요한 예방적 중앙 림프절절제술을 피하기 위해서 림프절 전이를 수술 전에 예측하는 수단이 필요하다. 림프관 생성 및 성장의 조절에 VEGF-C/D, VEGFR-3 pathway, podoplain이 관여된다는 사실이 밝혀져 있다. 림프관 생성 및 성장과 관련된 인자인 VEGF-C/D, podoplanin에 대한 면역조직화학염색과 반정량적 분석을 통해 미세갑상선유두상암종에서 림프절전이와의 관련성을 확인하고자 하였다. 대상 및 방법 : 2006년 9월부터 2008년 6월까지 본원에서 미세갑상선유두상암종으로 진단받고 1인 술자에 의해 갑상선 전 절제술 및 예방적 중앙 림프절절제술을 받은 104명의 환자 중 중앙 림프절 전이가 있었던 환자와 없었던 환자를 각각 25명씩 무작위로 선별하여 종양부위에 면역화학염색을 실시하여 림프관생성인자의 발현 정도를 비교하였다. 결 과 : 대상군 50예 중 VEGF-C/D는 50예(100%) 모두 발현이 되었고 podoplanin은 33예(66%)에서 발현이 되었다. 그 중 VEGF-C는 10예(20%)에서 약한 양성, 37예(74%)에서 중등도 양성, 3예(6%)에서 강한 양성소견을 보였고 VEGF-D는 9예(18%)에서 약한 양성, 37예(74%)에서 중등도 양성, 4예(8%)에서 강한 양성소견을 보였다. 중앙 림프절 전이 음성 환자 군과 양성 환자 군으로 분류하였을 때 VEGF-C/D의 발현율의 차이는 p-value가 각각 0.48, 1.00으로 통계적으로 유의한 차이를 보이지 않았다. 50예 전체를 대상으로 하여 종양의 개수, 최대크기, 검출된 전체 림프절의 수, 양성 림프절의 수, 주변조직 침범여부에 따른 VEGF-C/D의 발현도 통계적으로 유의한 차이를 보이지 않았다. Podoplanin의 경우 염색 여부에 따라 양성군과 음성군으로 나누어 분석하였을 때 종양의 개수, 최대크기, 검출된 림프절의 수, 양성 림프절의 수, 주변조직 침범여부도 통계적으로 유의한 차이를 보이지 않았다. 결 론 : VEGF-C/D는 대상군 전체(100%)에서 발현이 되었고 podoplanin은 66%에서 발현이 되었다. 림프관 생성인자로 알려진 VEGF-C/D및 podoplanin이 미세갑상선유두상암종에서 많이 발현이 되는 것으로 보아 위 인자들이 림프절 전이를 일으키는 인자 중 하나로 생각된다. 하지만 미세갑상선유두상암종에서 중앙 림프절 전이를 예측할 수 있는 인자로 부적합 한 것으로 생각되며 향후 더 많은 증례를 통해 관련성 여부에 대한 연구가 필요하고 또 다른 인자의 관련성에 대해서 연구가 필요하겠다.