• Title/Summary/Keyword: 양성우

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Relationship Between IFN${\gamma}$ Production, Antibody and Hormone Levels in Naturally Neospora caninum-infected Pregnant Dairy Cows (Neospora caninum에 자연 감염된 임신우에서 IFN${\gamma}$, 항체 및 호르몬 수준의 상관관계)

  • Son, Jeong-Hoon;Park, Bae-Keun;Son, Hwa-Young;Jung, Ju-Young;Park, Sang-Joon;Kim, Tae-Hwan;Cho, Sung-Whan;Ryu, Si-Yun
    • Journal of Veterinary Clinics
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    • v.27 no.6
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    • pp.640-646
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    • 2010
  • Neosporosis is a widespread parasitic disease caused by Neospora caninum, an intracellular protozoan parasite. It causes economic losses due to reproductive failure. The potential relationship between pregnancy outcomes and levels of IFN${\gamma}$, hormones, and antibodies in naturally N. caninum-infected cows was examined in the blood samples collected every 2 or 4 weeks in 26 pregnant cows from 4 different farms. The mean S/P value of seropositive nonaborting animals (n = 14) reached peak levels 15 weeks prior to parturition, and declined thereafter to parturition. The S/P value 13 weeks prior to abortion in seropositive aborting cows (n=3) remained at high levels, and abortions occurred at 20 (142 days), 26 (185 days), and 28 weeks (199 days) after artificial insemination. IFN${\gamma}$ levels in the seropositive non-aborting group varied by individuals and gestational periods; IFN${\gamma}$ levels stayed at elevated levels or increased abruptly close to abortion in seropositive aborting cows. IFN${\gamma}$ level patterns in the seronegative group (n = 9) were similar to the seropositive non-aborting group, although IFN${\gamma}$ amounts were lower than the seropositive group. The mean progesterone levels in the seropositive non-aborting and seronegative groups decreased markedly 7 weeks prior to parturition. The mean progesterone levels 5 and 7 weeks prior to abortion were lower than the other groups 5 and 7 weeks prior to parturition. The mean 17${\beta}$-estradiol levels in the seropositive aborting cows increased close to abortion; the produced amounts were lower than those of seropositive non-aborting and seronegative groups close to parturition. These results suggested that lower levels of progesterone and ${\beta}$-estradiol in Neospora-infected cows may lead to increases in IFN${\gamma}$ production and in turn may result in abortion.

Seroepizootiological Study on Bovine Leucosis in Korea (한국(韓國)에서의 소백혈병(白血病)의 혈청역학적(血淸疫學的) 연구(硏究))

  • Jun, Moo-Hyung;Chung, Un-Ik;Lee, Chang-Ku;Baig, Soon-Yong;Lim, Chang-Hyeong
    • Korean Journal of Veterinary Research
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    • v.22 no.2
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    • pp.175-185
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    • 1982
  • Since bovine lymphosarcoma causes considerable economic loss to the dairy industry, seroepidemiological survey on bovine leucosis virus (BLV) was carried out for the dairy herds throughout the country to observe the epidemiological situation of the disease by using immunodiffusion test. Attempts were simultaneously made to detect bovine leucosis virus in the lymphocytes from BLV antibody-positive cattle by means of fluorescent antibody techniques, syncytium assay and electron microscopy. In immunodiffusion test for BLV antibody in 2003 heads of dairy cattle selected randomly from 164 herds, the prevalence of positive reactors by regions were 37.8% in Central, 27.2% in Honam (Southwest), 28.0% in Youngnam (Southeast) and 25.2% in Youngdong (East coast)and averaging 29.7%. By provinces, Chungcheong appeared the highest prevalence of BLV antibody carriers (41.8%), while Jeonbug revealed the lowest incidence rate (24.4%). When the results of serological studies were analyzed by age groups and the sizes of herds, the number of reactors increased gradually with the advance in the age of cattle and the herd size. The highest rate of BLV carriers was found in the ages between 6 and 8 years, and in the size of herds with 20 to 50 heads. One hundred and seventeen breeding bulls from the central regions were tested for BLV antibody. Four out of 70 bulls (5.7%) of Korean cattle and 14 out of 39 bulls (35.9%) of Holstein were reactive for BLV antigens. Of 164 dairy herds examined, 17 herds (10.4%) have no BLV antibody-positive cattle, while 42 herds (25.6%) were included in the range of 20 to 40% of the positive rate and 10 herds (6.1%) in the range of over 80% of the rate. When the lymphocytes from the BLV antibody carrying cattle were cultured in the presence of phytohemagglutinin and stained with FITC-conjugated sheep anti-BLV serum, 8 out of 11 cases (72.7%) of BLV positive cattle revealed specific fluorescence for BLV in the lymphocytes. In syncytium assay of the peripheral lymphocytes of the cattle, 5 out of 7 (71.4%) lymphocytes from BLV antibody carriers induced syncytia in the indicators of bovine embryonic splenic cells. The cultured lymphocytes were examined with an electron microscope to detect the BLV particles. Two out of 6 specimens (33.3%) from the reactors showed the typical type C virus with the size of 90 to 110 nm around microvilli and in intracytoplasmic vacuoles.

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Clustering For Detecting Ethereum-Based Scam Coins (클러스터링을 이용한 이더리움 기반 스캠 코인 탐지 연구)

  • Bae, Yujin;Hwang, Yuna;Kang, Myungseok;Lee, Seungwoo;Kim, Sungsu;Choi, Yunam;Kim, Hyunmin;Kim, Kyung-gon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2021.11a
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    • pp.247-250
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    • 2021
  • 최근 스캠 코인에 의한 피해 사례가 증가함에 따라 대부분의 가상자산 거래소가 상장된 가상자산에 대해 자체적 신뢰도 평가를 수행하고 있으나, 관련 법·제도적 체계의 부재로 인해 여전히 위험이 존재한다. 스캠 코인 여부를 판단하는 기존 서비스는 불명확한 스캠 코인 판별 기준으로 인해 충분히 신뢰하기 어려우며, 지도 학습에 필요한 라벨링 된 데이터셋이 충분하지 않아 관련 연구 또한 한계를 가진다. 본 논문은 클러스터링을 통해 스캠 코인 여부를 판단하는 것을 목표로 한다. 스캠 코인과 정상적인 가상자산을 구분하는 과정에서 유의미한 데이터를 수집하여 클러스터링을 수행하고, 스캠 코인 여부가 라벨링 된 테스트셋을 구성하여 클러스터링 결과를 평가한다. 이를 통해 본 논문이 제시하는 이더리움 기반 토큰에 대한 클러스터링 결과를 기반으로 추후 통일된 스캠 코인 판단 기준을 세울 수 있음을 제안한다.

정보보호 인력양성 방안에 관한 연구

  • 이형우;이민섭
    • Review of KIISC
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    • v.13 no.2
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    • pp.70-80
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    • 2003
  • 본 연구에서는 대학 및 정보보호 관련 교육기관을 중심으로 활발히 진행되고 있는 정보보호 인력양성 과정 및 체계를 살펴보고 정보보호 산업 현황을 분석하여 정보보호 인력 양성 방안을 살펴보았다. 우선 정보보호 인력의 기준 및 조건을 검토하고 정보보호 인력이 갖추어야 하는 전공 지식 분야를 분류하였다. 특히 정보보호 교육기관에서의 정보보호 관련 전공 및 유사전공을 통해서 수행되는 인력양성 방안을 기초로 산업계에서 필요로 하는 정보보호 인력양성 방안을 고찰해본다.